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List of works by Yumiko Saga

Activation of Notch1 signaling in cardiogenic mesoderm induces abnormal heart morphogenesis in mouse

scientific article

Analysis of Ripply1/2-deficient mouse embryos reveals a mechanism underlying the rostro-caudal patterning within a somite

scientific journal article

Appropriate suppression of Notch signaling by Mesp factors is essential for stripe pattern formation leading to segment boundary formation

scientific article published on 9 January 2007

Assessment of quantitative dual-parameter flow cytometric analysis for the evaluation of testicular toxicity using cyclophosphamide- and ethinylestradiol-treated rats

scientific article

Characterization of size-fractionated cDNA libraries generated by the in vitro recombination-assisted method

scientific article (publication date: 30 April 2002)

Cooperative Mesp activity is required for normal somitogenesis along the anterior-posterior axis

scientific article

Dead end1 is an essential partner of NANOS2 for selective binding of target RNAs in male germ cell development

scientific article

Development of humanized steroid and xenobiotic receptor mouse by homologous knock-in of the human steroid and xenobiotic receptor ligand binding domain sequence ⬇️

scientific article published on January 1, 2012

Differential contributions of Mesp1 and Mesp2 to the epithelialization and rostro-caudal patterning of somites

scientific article published in February 2005

ELAVL2-directed RNA regulatory network drives the formation of quiescent primordial follicles

scientific article published on 28 October 2019

Ectopic retinoic acid signaling affects outflow tract cushion development through suppression of the myocardial Tbx2-Tgfβ2 pathway ⬇️

scientific article published on January 1, 2012

Feedback loops comprising Dll1, Dll3 and Mesp2, and differential involvement of Psen1 are essential for rostrocaudal patterning of somites

scientific article published in September 2003

Functional importance of evolutionally conserved Tbx6 binding sites in the presomitic mesoderm-specific enhancer of Mesp2.

scientific article published in November 2008

Genetic and structural analysis of the in vivo functional redundancy between murine NANOS2 and NANOS3

scientific article published on 16 November 2020

Hesr1 and Hesr2 regulate atrioventricular boundary formation in the developing heart through the repression of Tbx2

scientific article

Hesr1 knockout mice exhibit behavioral alterations through the dopaminergic nervous system

scientific article published in November 2006

Hesr2 Knockout Mice Develop Aortic Valve Disease With Advancing Age ⬇️

scientific article published on January 3, 2013

Hypomorphic Mesp allele distinguishes establishment of rostrocaudal polarity and segment border formation in somitogenesis.

scientific article published in May 2002

Identification of Epha4 enhancer required for segmental expression and the regulation by Mesp2.

scientific article

Identification of presomitic mesoderm (PSM)-specific Mesp1 enhancer and generation of a PSM-specific Mesp1/Mesp2-null mouse using BAC-based rescue technology

scientific article published on 5 February 2008

Implication of nanos2-3'UTR in the expression and function of nanos2.

scientific article published on 6 May 2006

Lfng regulates the synchronized oscillation of the mouse segmentation clock via trans-repression of Notch signalling

scientific journal article

Mastermind-like 1 (MamL1) and mastermind-like 3 (MamL3) are essential for Notch signaling in vivo ⬇️

scientific article published on December 1, 2011

Mesp1-nonexpressing cells contribute to the ventricular cardiac conduction system

scientific article published in February 2006

Mouse Nkd1, a Wnt antagonist, exhibits oscillatory gene expression in the PSM under the control of Notch signaling

scientific article published in December 2004

Mutant analyses reveal different functions of fgfr1 in medaka and zebrafish despite conserved ligand-receptor relationships

scientific article published on 23 December 2006

NANOS2 interacts with the CCR4-NOT deadenylation complex and leads to suppression of specific RNAs

scientific journal article

NANOS3 suppresses premature spermatogonial differentiation to expand progenitors and fine-tunes spermatogenesis in mice

scientific article published on 08 April 2022

NEDD4 controls spermatogonial stem cell homeostasis and stress response by regulating messenger ribonucleoprotein complexes

scientific article

Nanos3 maintains the germ cell lineage in the mouse by suppressing both Bax-dependent and -independent apoptotic pathways

scientific journal article

Notch signaling is required for the maintenance of enteric neural crest progenitors

scientific article published on 2 October 2008

Phenotypic analysis of a novel chordin mutant in medaka

scientific article published on 01 August 2007

Prediction of the coding sequences of mouse homologues of FLJ genes: the complete nucleotide sequences of 110 mouse FLJ-homologous cDnas identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries

scientific article published in April 2004

Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libra

scientific article

Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated librar

scientific article

Ripply2 recruits proteasome complex for Tbx6 degradation to define segment border during murine somitogenesis.

scientific article published on 15 May 2018

Spatiotemporal disorder in the axial skeleton development of the Mesp2-null mouse: a model of spondylocostal dysostosis and spondylothoracic dysostosis

scientific article published on 11 December 2012

Tbx6-mediated Notch signaling controls somite-specific Mesp2 expression

scholarly article

The Mesp2 transcription factor establishes segmental borders by suppressing Notch activity

scientific journal article

The auxin-inducible degron 2 technology provides sharp degradation control in yeast, mammalian cells, and mice

scientific article published on 11 November 2020

The establishment of rotational polarity in the airway and ependymal cilia: analysis with a novel cilium motility mutant mouse

scientific article

The negative regulation of Mesp2 by mouse Ripply2 is required to establish the rostro-caudal patterning within a somite

scientific article published on 14 March 2007

The oscillation of Notch activation, but not its boundary, is required for somite border formation and rostral-caudal patterning within a somite

scientific article published on 24 March 2010

The protocadherin papc is involved in the organization of the epithelium along the segmental border during mouse somitogenesis

scientific journal article

The repression of Notch signaling occurs via the destabilization of mastermind-like 1 by Mesp2 and is essential for somitogenesis ⬇️

scientific article published on November 23, 2010

Transcription factors Mesp2 and Paraxis have critical roles in axial musculoskeletal formation

scientific article published in June 2007

Transgenic analysis of the medaka mesp-b enhancer in somitogenesis

scientific article published on 01 April 2006

Wnt signaling maintains the notochord fate for progenitor cells and supports the posterior extension of the notochord.

scientific article published on 29 August 2009

nanos1: a mouse nanos gene expressed in the central nervous system is dispensable for normal development

scientific article published in June 2003

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