List of works - Ratnesh Lal

A novel role for connexin hemichannel in oxidative stress and smoking-induced cell injury

scientific article

All-d-Enantiomer of β-Amyloid Peptide Forms Ion Channels in Lipid Bilayers

scientific article

Alzheimer's disease: which type of amyloid-preventing drug agents to employ?

scientific article

Alzheimer's β-Amyloid All-D-Enantiomers and Native All-L-Enantiomers Exhibit Similar Pore Structures in Lipid Bilayers: Atomic Force Microscopy

Amyloid β Ion Channels in a Membrane Comprising Brain Total Lipid Extracts

scientific article

Antimicrobial properties of amyloid peptides

scientific article published on 29 November 2011

Antimicrobial protegrin-1 forms amyloid-like fibrils with rapid kinetics suggesting a functional link

scientific article

Antimicrobial protegrin-1 forms ion channels: molecular dynamic simulation, atomic force microscopy, and electrical conductance studies

scientific article

Atomic force microscopy and MD simulations reveal pore-like structures of all-D-enantiomer of Alzheimer's β-amyloid peptide: relevance to the ion channel mechanism of AD pathology

scientific article

Atomic force microscopy imaging and electrical recording of lipid bilayers supported over microfabricated silicon chip nanopores: lab-on-a-chip system for lipid membranes and ion channels

scientific article published in January 2007

Cisplatin nanoliposomes for cancer therapy: AFM and fluorescence imaging of cisplatin encapsulation, stability, cellular uptake, and toxicity

scientific article published on September 2006

Computational Methods for Structural and Functional Studies of Alzheimer's Amyloid Ion Channels.

scientific article

DNA Hydrogel with Aptamer-Toehold-Based Recognition, Cloaking, and Decloaking of Circulating Tumor Cells for Live Cell Analysis.

scientific article published on 3 August 2017

DNA Nanotweezers and Graphene Transistor Enable Label-Free Genotyping

scientific article published on 09 July 2018

DNA Zippers and Regenerative Nano-Gates

DNA zipper-based tweezers

scientific article published on 15 September 2011

Disordered amyloidogenic peptides may insert into the membrane and assemble into common cyclic structural motifs

scientific article

Effects of point substitutions on the structure of toxic Alzheimer's β-amyloid channels: atomic force microscopy and molecular dynamics simulations

scientific article published on 28 March 2012

Familial Alzheimer's disease Osaka mutant (ΔE22) β-barrels suggest an explanation for the different Aβ1-40/42 preferred conformational states observed by experiment

scientific article

Generating Cyan Fluorescence with De Novo Tripeptides: An In Vitro Mutation Study on the Role of Single Amino Acid Residues and Their Sequence

scientific article published on 29 July 2019

Gold-Embedded Hollow Silica Nanogolf Balls for Imaging and Photothermal Therapy

scientific article published on 28 July 2017

Graphite-Templated Amyloid Nanostructures Formed by a Potential Pentapeptide Inhibitor for Alzheimer's Disease: A Combined Study of Real-Time Atomic Force Microscopy and Molecular Dynamics Simulations

scientific article published on 12 June 2017

Heme Oxygenase-1 at the Nexus of Endothelial Cell Fate Decision Under Oxidative Stress

scientific article published on 14 September 2021

High performance, LED powered, waveguide based total internal reflection microscopy

scientific article

Hollow Disc and Sphere-Shaped Particles from Red Blood Cell Templates

Integrated sensors and BioMEMS for in vitro high throughput biomarkers and drug discovery

Ion Channel Formation by Tau Protein: Implications for Alzheimer's Disease and Tauopathies

scientific article

K3 fragment of amyloidogenic beta(2)-microglobulin forms ion channels: implication for dialysis related amyloidosis

scientific article published on October 2009

Lipid-Encapsulated Silica Nanobowls as an Efficient and Versatile DNA Delivery System

scientific article published on 24 November 2020

Magnetic targeting of nanoparticles across the intact blood-brain barrier

scientific article published on 10 October 2012

Measuring localized redox enzyme electron transfer in a live cell with conducting atomic force microscopy

scientific article

Mechanisms for the Insertion of Toxic, Fibril-like β-Amyloid Oligomers into the Membrane

scientific article

Misfolded amyloid ion channels present mobile beta-sheet subunits in contrast to conventional ion channels

scientific article published on December 2009

Modeling Alzheimer's Ion Channel Structures in Lipid Bilayers Formed by D- and L-Enantiomers of Beta-Amyloid (1-42) Peptide

Modeling Ion-Permeable β-Amyloid (Aβ) Barrels in the Lipid Bilayer

Modeling Variants of Alzheimer's Ion Channels in the Lipid Bilayer formed by an Aggregation-Intermediate β-Hairpin and E22Δ Mutant

Models of toxic beta-sheet channels of protegrin-1 suggest a common subunit organization motif shared with toxic alzheimer beta-amyloid ion channels

scientific article published on 15 August 2008

Multidimensional Atomic Force Microscopy: A Versatile Novel Technology for Nanopharmacology Research ⬇️

scientific article published on October 19, 2010

Multidimensional atomic force microscopy for drug discovery: a versatile tool for defining targets, designing therapeutics and monitoring their efficacy

scientific article published on 26 April 2009

Mutant SOD1 forms ion channel: implications for ALS pathophysiology

scientific article

Nanobiotechnology for neurodegenerative and protein-misfolding diseases

Nanomechanics of hemichannel conformations: connexin flexibility underlying channel opening and closing

scientific article

New structures help the modeling of toxic amyloidbeta ion channels

scientific article published on 07 January 2008

Oligomerization of the microtubule-associated protein tau is mediated by its N-terminal sequences: implications for normal and pathological tau action

scientific article published on 8 March 2016

Piezoresistive cantilever based nanoflow and viscosity sensor for microchannels

scientific article

Polymorphism of amyloid β peptide in different environments: implications for membrane insertion and pore formation

scientific article

Potential role of atomic force microscopy in systems biology

scientific article

Probing structural features of Alzheimer's amyloid-β pores in bilayers using site-specific amino acid substitutions

scientific article published on 12 January 2012

Regulation of the micromechanical properties of pulmonary endothelium by S1P and thrombin: role of cortactin

scientific article published on 11 April 2008

Scope of atomic force microscopy in the advancement of nanomedicine

scientific article published on October 2010

Small molecule NPT-440-1 inhibits ionic flux through Aβ1-42 pores: Implications for Alzheimer's disease therapeutics

scientific article published on 19 June 2016

Structural convergence among diverse, toxic beta-sheet ion channels

scientific article

Structure and permeability of ion-channels by integrated AFM and waveguide TIRF microscopy

scientific article published on 21 March 2014

Structure–Function Studies of Amyloid Pores in Alzheimer’s Disease as a Case Example of Neurodegenerative Diseases

Sub-nanowatt microfluidic single-cell calorimetry

scientific article published on 12 June 2020

The diphenylpyrazole compound anle138b blocks Aβ channels and rescues disease phenotypes in a mouse model for amyloid pathology.

scientific article published on 5 December 2017

Transmembrane β-Barrel Topology Model for Alzheimer's β-Amyloid (Aβ) Ion Channels

article published in 2011

Truncated beta-amyloid peptide channels provide an alternative mechanism for Alzheimer's Disease and Down syndrome

scientific article

Tunable and Regenerative DNA Zipper Based Spring

article

β-Barrel topology of Alzheimer's β-amyloid ion channels

scientific article

List of works by Ratnesh Lal

A novel role for connexin hemichannel in oxidative stress and smoking-induced cell injury

All-d-Enantiomer of β-Amyloid Peptide Forms Ion Channels in Lipid Bilayers

Alzheimer's disease: which type of amyloid-preventing drug agents to employ?

Alzheimer's β-Amyloid All-D-Enantiomers and Native All-L-Enantiomers Exhibit Similar Pore Structures in Lipid Bilayers: Atomic Force Microscopy

Amyloid β Ion Channels in a Membrane Comprising Brain Total Lipid Extracts

Antimicrobial properties of amyloid peptides

Antimicrobial protegrin-1 forms amyloid-like fibrils with rapid kinetics suggesting a functional link

Antimicrobial protegrin-1 forms ion channels: molecular dynamic simulation, atomic force microscopy, and electrical conductance studies

Atomic force microscopy and MD simulations reveal pore-like structures of all-D-enantiomer of Alzheimer's β-amyloid peptide: relevance to the ion channel mechanism of AD pathology

Atomic force microscopy imaging and electrical recording of lipid bilayers supported over microfabricated silicon chip nanopores: lab-on-a-chip system for lipid membranes and ion channels

Cisplatin nanoliposomes for cancer therapy: AFM and fluorescence imaging of cisplatin encapsulation, stability, cellular uptake, and toxicity

Computational Methods for Structural and Functional Studies of Alzheimer's Amyloid Ion Channels.

DNA Hydrogel with Aptamer-Toehold-Based Recognition, Cloaking, and Decloaking of Circulating Tumor Cells for Live Cell Analysis.

DNA Nanotweezers and Graphene Transistor Enable Label-Free Genotyping

DNA Zippers and Regenerative Nano-Gates

DNA zipper-based tweezers

Disordered amyloidogenic peptides may insert into the membrane and assemble into common cyclic structural motifs

Effects of point substitutions on the structure of toxic Alzheimer's β-amyloid channels: atomic force microscopy and molecular dynamics simulations

Familial Alzheimer's disease Osaka mutant (ΔE22) β-barrels suggest an explanation for the different Aβ1-40/42 preferred conformational states observed by experiment

Generating Cyan Fluorescence with De Novo Tripeptides: An In Vitro Mutation Study on the Role of Single Amino Acid Residues and Their Sequence

Gold-Embedded Hollow Silica Nanogolf Balls for Imaging and Photothermal Therapy

Graphite-Templated Amyloid Nanostructures Formed by a Potential Pentapeptide Inhibitor for Alzheimer's Disease: A Combined Study of Real-Time Atomic Force Microscopy and Molecular Dynamics Simulations

Heme Oxygenase-1 at the Nexus of Endothelial Cell Fate Decision Under Oxidative Stress

High performance, LED powered, waveguide based total internal reflection microscopy

Hollow Disc and Sphere-Shaped Particles from Red Blood Cell Templates

Integrated sensors and BioMEMS for in vitro high throughput biomarkers and drug discovery

Ion Channel Formation by Tau Protein: Implications for Alzheimer's Disease and Tauopathies

K3 fragment of amyloidogenic beta(2)-microglobulin forms ion channels: implication for dialysis related amyloidosis

Lipid-Encapsulated Silica Nanobowls as an Efficient and Versatile DNA Delivery System

Magnetic targeting of nanoparticles across the intact blood-brain barrier

Measuring localized redox enzyme electron transfer in a live cell with conducting atomic force microscopy

Mechanisms for the Insertion of Toxic, Fibril-like β-Amyloid Oligomers into the Membrane

Misfolded amyloid ion channels present mobile beta-sheet subunits in contrast to conventional ion channels

Modeling Alzheimer's Ion Channel Structures in Lipid Bilayers Formed by D- and L-Enantiomers of Beta-Amyloid (1-42) Peptide

Modeling Ion-Permeable β-Amyloid (Aβ) Barrels in the Lipid Bilayer

Modeling Variants of Alzheimer's Ion Channels in the Lipid Bilayer formed by an Aggregation-Intermediate β-Hairpin and E22Δ Mutant

Models of toxic beta-sheet channels of protegrin-1 suggest a common subunit organization motif shared with toxic alzheimer beta-amyloid ion channels

Multidimensional Atomic Force Microscopy: A Versatile Novel Technology for Nanopharmacology Research ⬇️

Multidimensional atomic force microscopy for drug discovery: a versatile tool for defining targets, designing therapeutics and monitoring their efficacy

Mutant SOD1 forms ion channel: implications for ALS pathophysiology

Nanobiotechnology for neurodegenerative and protein-misfolding diseases

Nanomechanics of hemichannel conformations: connexin flexibility underlying channel opening and closing

New structures help the modeling of toxic amyloidbeta ion channels

Oligomerization of the microtubule-associated protein tau is mediated by its N-terminal sequences: implications for normal and pathological tau action

Piezoresistive cantilever based nanoflow and viscosity sensor for microchannels

Polymorphism of amyloid β peptide in different environments: implications for membrane insertion and pore formation

Potential role of atomic force microscopy in systems biology

Probing structural features of Alzheimer's amyloid-β pores in bilayers using site-specific amino acid substitutions

Regulation of the micromechanical properties of pulmonary endothelium by S1P and thrombin: role of cortactin

Scope of atomic force microscopy in the advancement of nanomedicine

Small molecule NPT-440-1 inhibits ionic flux through Aβ1-42 pores: Implications for Alzheimer's disease therapeutics

Structural convergence among diverse, toxic beta-sheet ion channels

Structure and permeability of ion-channels by integrated AFM and waveguide TIRF microscopy

Structure–Function Studies of Amyloid Pores in Alzheimer’s Disease as a Case Example of Neurodegenerative Diseases

Sub-nanowatt microfluidic single-cell calorimetry

The diphenylpyrazole compound anle138b blocks Aβ channels and rescues disease phenotypes in a mouse model for amyloid pathology.

Transmembrane β-Barrel Topology Model for Alzheimer's β-Amyloid (Aβ) Ion Channels

Truncated beta-amyloid peptide channels provide an alternative mechanism for Alzheimer's Disease and Down syndrome

Tunable and Regenerative DNA Zipper Based Spring

β-Barrel topology of Alzheimer's β-amyloid ion channels