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List of works by Vera P Krymskaya

Abnormal growth of smooth muscle-like cells in lymphangioleiomyomatosis: Role for tumor suppressor TSC2

scientific article

Airway smooth muscle cells enhance C3a-induced mast cell degranulation following cell-cell contact.

scientific article

An RGS4-mediated phenotypic switch of bronchial smooth muscle cells promotes fixed airway obstruction in asthma

scientific article

Assays for in vitro monitoring of human airway smooth muscle (ASM) and human pulmonary arterial vascular smooth muscle (VSM) cell migration

scientific article published on January 2006

Cross-talk between tuberin, calmodulin, and estrogen signaling pathways

scientific article published on 25 April 2005

Cyclic AMP-mobilizing agents and glucocorticoids modulate human smooth muscle cell migration

scientific article published on 31 January 2003

DHEA-S inhibits human neutrophil and human airway smooth muscle migration ⬇️

scientific article published on July 3, 2012

Differential effects of formoterol on thrombin- and PDGF-induced proliferation of human pulmonary arterial vascular smooth muscle cells

scientific article published on 27 November 2012

Doxycycline reduces the migration of tuberous sclerosis complex-2 null cells - effects on RhoA-GTPase and focal adhesion kinase

scientific article

Folliculin controls lung alveolar enlargement and epithelial cell survival through E-cadherin, LKB1, and AMPK.

scientific article

Folliculin, the product of the Birt-Hogg-Dube tumor suppressor gene, interacts with the adherens junction protein p0071 to regulate cell-cell adhesion

scientific article

Idiopathic multicentric Castleman's disease: a systematic literature review

scientific article published on 17 March 2016

Interferon beta augments tuberous sclerosis complex 2 (TSC2)-dependent inhibition of TSC2-null ELT3 and human lymphangioleiomyomatosis-derived cell proliferation

scientific article

Interferons modulate mitogen-induced protein synthesis in airway smooth muscle

scientific article

International, evidence-based consensus diagnostic criteria for HHV-8-negative/idiopathic multicentric Castleman disease

scientific article

International, evidence-based consensus treatment guidelines for idiopathic multicentric Castleman disease

scientific article published on 04 September 2018

Lymphangioleiomyomatosis: A Monogenic Model of Malignancy

scientific article published on January 2017

Mammalian target of rapamycin complex 2 (mTORC2) coordinates pulmonary artery smooth muscle cell metabolism, proliferation, and survival in pulmonary arterial hypertension

scientific article

Modulation of cell migration and invasiveness by tumor suppressor TSC2 in lymphangioleiomyomatosis

scientific article published on 30 December 2005

PI3K/mTORC1 activation in hamartoma syndromes: therapeutic prospects

scientific article published on 06 February 2009

Pharmacological targeting of VEGFR signaling with axitinib inhibits Tsc2-null lesion growth in the mouse model of lymphangioleiomyomatosis

scientific article

Phosphatidylinositol 3-kinase but not tuberin is required for PDGF-induced cell migration

scientific article published on April 2002

Phosphodiesterases regulate airway smooth muscle function in health and disease

scientific article published on January 2007

Prevention of alveolar destruction and airspace enlargement in a mouse model of pulmonary lymphangioleiomyomatosis (LAM)

scientific article

Pulmonary lymphangioleiomyomatosis (LAM): progress and current challenges

scientific article published on February 2008

Rapamycin Prevents Seizures After Depletion of STRADA in a Rare Neurodevelopmental Disorder ⬇️

scientific article published on April 24, 2013

Rapamycin-independent IGF2 expression in Tsc2-null mouse embryo fibroblasts and human lymphangioleiomyomatosis cells.

scientific article published on 14 May 2018

Signal transducer and activator of transcription 3 is required for abnormal proliferation and survival of TSC2-deficient cells: relevance to pulmonary lymphangioleiomyomatosis.

scientific article published on 13 July 2009

Smooth muscle-like cells in pulmonary lymphangioleiomyomatosis

scientific article published on January 2008

Statins in lymphangioleiomyomatosis. Simvastatin and atorvastatin induce differential effects on tuberous sclerosis complex 2-null cell growth and signaling

scientific article

Surfactant dysfunction and lung inflammation in the female mouse model of lymphangioleiomyomatosis

scientific article

TSC2 modulates actin cytoskeleton and focal adhesion through TSC1-binding domain and the Rac1 GTPase

scientific journal article

TSC2 modulates cell adhesion and migration via integrin-α1β1 ⬇️

scientific article published on August 24, 2012

Targeted approaches toward understanding and treating pulmonary lymphangioleiomyomatosis (LAM)

scientific article published on 27 November 2012

Targeting the phosphatidylinositol 3-kinase pathway in airway smooth muscle: rationale and promise

scientific article published on January 2007

The PP2A-associated protein alpha4 plays a critical role in the regulation of cell spreading and migration

scientific article published on 10 August 2007

Therapeutic Strategies for Treatment of Pulmonary Lymphangioleiomyomatosis (LAM)

scientific article

Treatment option(s) for pulmonary lymphangioleiomyomatosis: progress and current challenges

scientific article published in May 2012

Tuberin regulates p70 S6 kinase activation and ribosomal protein S6 phosphorylation. A role for the TSC2 tumor suppressor gene in pulmonary lymphangioleiomyomatosis (LAM)

scientific journal article

Tumor suppressors TSC1 and TSC2 differentially modulate actin cytoskeleton and motility of mouse embryonic fibroblasts

scientific article

Tumour suppressors hamartin and tuberin: intracellular signalling

scientific article

Urokinase-type plasminogen activator (uPA) is critical for progression of tuberous sclerosis complex 2 (TSC2)-deficient tumors.

scientific article published on 27 September 2017

Wild type mesenchymal cells contribute to the lung pathology of lymphangioleiomyomatosis

scientific article published on 15 May 2015

mTOR is required for pulmonary arterial vascular smooth muscle cell proliferation under chronic hypoxia ⬇️

scientific article published on March 2, 2011

mTORC1 activation in lung mesenchyme drives sex- and age-dependent pulmonary structure and function decline

scientific article published on 06 November 2020

mTORC2 Is Required for Proliferation and Survival of TSC2-Null Cells ⬇️

scientific article published on April 11, 2011

β2-Adrenergic Receptor Agonists Modulate Human Airway Smooth Muscle Cell Migration via Vasodilator-Stimulated Phosphoprotein ⬇️

scientific article published on January 1, 2012

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