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List of works by Shuo-Chien Ling

Cell-autonomous requirement of TDP-43, an ALS/FTD signature protein, for oligodendrocyte survival and myelination

article published in the Proceedings of the National Academy of Sciences of the United States of America

Characterization of Granular Particles Isolated from Postsynaptic Densities ⬇️

scientific article published on October 1, 1998

Deregulated expression of a longevity gene, Klotho, in the C9orf72 deletion mice with impaired synaptic plasticity and adult hippocampal neurogenesis

scientific article published on 04 September 2020

Dysfunction in nonsense-mediated decay, protein homeostasis, mitochondrial function, and brain connectivity in ALS-FUS mice with cognitive deficits

scientific article published on 06 January 2021

Elevated FUS levels by overriding its autoregulation produce gain-of-toxicity properties that disrupt protein and RNA homeostasis

scientific article published on 23 June 2019

Fused in Sarcoma (FUS) Protein Lacking Nuclear Localization Signal (NLS) and Major RNA Binding Motifs Triggers Proteinopathy and Severe Motor Phenotype in Transgenic Mice ⬇️

scientific article published on July 18, 2013

Loss of TDP-43 in astrocytes leads to motor deficits by triggering A1-like reactive phenotype and triglial dysfunction

scientific article published on 30 October 2020

Ooplasmic flow cooperates with transport and anchorage in Drosophila oocyte posterior determination.

scientific article

Overriding FUS autoregulation in mice triggers gain-of-toxic dysfunctions in RNA metabolism and autophagy-lysosome axis

article

Synaptic Paths to Neurodegeneration: The Emerging Role of TDP-43 and FUS in Synaptic Functions.

scientific article

The ALS-FTD-linked gene product, C9orf72, regulates neuronal morphogenesis via autophagy

article

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