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List of works by David J. Pinato

A novel and validated prognostic index in hepatocellular carcinoma: the inflammation based index (IBI).

scientific article published on 23 June 2012

A novel, externally validated inflammation-based prognostic algorithm in hepatocellular carcinoma: the prognostic nutritional index (PNI)

scientific article published on 20 March 2012

A pilot randomized, placebo controlled, double blind phase I trial of the novel SIRT1 activator SRT2104 in elderly volunteers

scientific article

Acceleration of interstitial lung disease induced by raltitrexed

scientific article published on 19 November 2019

Advanced age influences the dynamic changes in circulating C-reactive protein following injury.

scientific article published on 28 March 2013

Alterations of choline phospholipid metabolism in endometrial cancer are caused by choline kinase alpha overexpression and a hyperactivated deacylation pathway

scientific article published on 29 September 2014

An expression signature of the angiogenic response in gastrointestinal neuroendocrine tumours: correlation with tumour phenotype and survival outcomes

scientific article

An inflammation based score can optimize the selection of patients with advanced cancer considered for early phase clinical trials

scientific article published on 07 January 2014

An inflammation-based prognostic index predicts survival advantage after transarterial chemoembolization in hepatocellular carcinoma

scientific article published on 30 January 2012

An unexpected cause of pulmonary cannonball lesion

scientific article published on 01 February 2014

Antibiotic Treatment and Immune Checkpoint Inhibitor Therapy in Patients With Cancer-Reply

scientific article published on 20 February 2020

Antibiotic therapy and outcome from immune-checkpoint inhibitors

scientific article published on 06 November 2019

Antibiotic-induced Dysbiosis as a Putative Actionable Driver of Cancer Immunity in Renal Cell Carcinoma

scientific article published on 23 May 2020

Applicability of Routine Targeted Next-generation Sequencing to Estimate Tumor Mutational Burden (TMB) in Patients Treated With Immune Checkpoint Inhibitor Therapy

scientific article published on 01 February 2020

Artemisia: a divine dart against cancer?

scientific article published on July 2015

Association of Prior Antibiotic Treatment With Survival and Response to Immune Checkpoint Inhibitor Therapy in Patients With Cancer

scientific article published on 12 September 2019

Biliary Tract Cancers: Molecular Heterogeneity and New Treatment Options

scientific article published on 13 November 2020

Blood Epstein-Barr virus DNA does not predict outcome in advanced HIV-associated Hodgkin lymphoma.

scientific article

Breaking Kuhn's paradigm in advanced hepatocellular carcinoma.

scientific article published on 8 December 2017

CD24: a potential new marker in differentiating malignant mesothelioma from pulmonary adenocarcinoma

scientific article published on 19 October 2012

Cancer-related inflammation: an emerging prognostic domain in metastatic castration-resistant prostate carcinoma

scientific article published on 3 July 2014

Capsaicin 8% patch for treprostinil subcutaneous infusion site pain in pulmonary hypertension patients

scientific article

Challenges and Opportunities in the Clinical Development of STING Agonists for Cancer Immunotherapy

scientific article published on 16 October 2020

Challenges and opportunities in the clinical development of immune checkpoint inhibitors for hepatocellular carcinoma

article

Circulating-free tumour DNA and the promise of disease phenotyping in hepatocellular carcinoma

scientific article published on 14 May 2018

Clinical implications of heterogeneity in PD-L1 immunohistochemical detection in hepatocellular carcinoma: the Blueprint-HCC study

scientific article published on 07 May 2019

Clinical portrait of the SARS-CoV-2 epidemic in European cancer patients

scientific article published on 31 July 2020

Clinical, ethical and financial implications of incidental imaging findings: experience from a phase I trial in healthy elderly volunteers.

scientific article

Combined PD-1/VEGFR blockade: a new era of treatment for hepatocellular cancer

scientific article published on 16 December 2020

Combined sequential use of HAP and ART scores to predict survival outcome and treatment failure following chemoembolization in hepatocellular carcinoma: a multi-center comparative study

scientific article published on 26 May 2016

Concomitant medications and immune checkpoint inhibitor therapy for cancer: causation or association?

scientific article published on 23 June 2020

Corrigendum to "A novel and validated prognostic index in hepatocellular carcinoma: The Inflammation Based Index (IBI)"

scientific article published on 16 June 2016

Developing an objective marker to optimize patient selection and predict survival benefit in early-phase cancer trials.

scientific article published on 8 October 2013

Dynamic changes of the inflammation-based index predict mortality following chemoembolisation for hepatocellular carcinoma: a prospective study

article

Editorial: a step forward in refining prognostication for patients with HIV-associated hepatocellular carcinoma-Authors' reply.

scientific article

Editorial: dynamic changes of the inflammation-based index predict mortality following chemoembolisation for hepatocellular carcinoma--authors' reply

scientific article published on 01 June 2015

Effect of concomitant medications with immune-modulatory properties on the outcomes of patients with advanced cancer treated with immune checkpoint inhibitors: development and validation of a novel prognostic index

scientific article published on 16 November 2020

Evaluation of the red cell distribution width as a biomarker of early mortality in hepatocellular carcinoma.

scientific article published on 19 March 2015

Evolution of HIV-Associated Lymphoma Over 3 Decades

scientific article

Evolving concepts in the management of drug resistant ovarian cancer: dose dense chemotherapy and the reversal of clinical platinum resistance

scientific article published on 16 May 2012

First-in-human study of CH5132799, an oral class I PI3K inhibitor, studying toxicity, pharmacokinetics, and pharmacodynamics, in patients with metastatic cancer

scientific article

Functional immune characterization of HIV-associated non-small-cell lung cancer

scientific article published on 01 June 2018

Gender-related distribution of the interleukin-1 beta and interleukin-1 receptor antagonist gene polymorphisms in patients with end-stage liver disease

scientific article published on 01 August 2010

Gene of the month: Axl.

scientific article published on 7 March 2016

Hepatitis B virus and lymphomagenesis: novel insights into an occult relationship

scientific article published on 12 October 2011

Hepatocellular carcinoma: an evolving challenge in viral hepatitis and HIV co-infection.

scientific article published on 24 January 2017

Histological Subtypes and Response to PD-1/PD-L1 Blockade in Advanced Urothelial Cancer: A Retrospective Study

scientific article published on 23 January 2020

Identification of mutations in circulating cell-free tumour DNA as a biomarker in hepatocellular carcinoma

scientific article published on 04 June 2019

Imatinib induced pyoderma gangrenosum

scientific article published on 01 July 2013

Immune Checkpoint Inhibitor Therapy in Patients With Preexisting Inflammatory Bowel Disease

scientific article published on 04 December 2019

Immune-based therapies for hepatocellular carcinoma

scientific article published on 10 March 2020

Immunohistochemical markers of the hypoxic response can identify malignancy in phaeochromocytomas and paragangliomas and optimize the detection of tumours with VHL germline mutations

scientific article published on 20 December 2012

Immunotherapy in Hepatocellular Cancer Patients with Mild to Severe Liver Dysfunction: Adjunctive Role of the ALBI Grade

scientific article published on 10 July 2020

Impact of age on sorafenib outcomes in hepatocellular carcinoma: an international cohort study

scientific article published on 19 October 2020

Impact of corticosteroid therapy on the outcomes of hepatocellular carcinoma treated with immune checkpoint inhibitor therapy

scientific article published on 01 October 2020

Impact of performance status on treatment outcomes: A real-world study of advanced urothelial cancer treated with immune checkpoint inhibitors

scientific article published on 12 December 2019

Inflammation as a validated prognostic determinant in carcinoma of unknown primary site

scientific article published on 29 October 2013

Inflammation-based prognostic indices in malignant pleural mesothelioma

scientific article published in March 2012

Influence of HIV Infection on the Natural History of Hepatocellular Carcinoma: Results From a Global Multicohort Study

scientific article published on 18 December 2018

Integrated analysis of concomitant medications and oncological outcomes from PD-1/PD-L1 checkpoint inhibitors in clinical practice

scientific article published on 01 November 2020

Integrated analysis of multiple receptor tyrosine kinases identifies Axl as a therapeutic target and mediator of resistance to sorafenib in hepatocellular carcinoma

scientific article published on 15 February 2019

Integration of the cancer-related inflammatory response as a stratifying biomarker of survival in hepatocellular carcinoma treated with sorafenib

scientific article

Interleukin-6 polymorphisms and gender: relationship with the occurrence of hepatocellular carcinoma in patients with end-stage liver disease

scientific article published on 20 November 2009

Intra-tumoral heterogeneity in the expression of programmed-death (PD) ligands in isogeneic primary and metastatic lung cancer: Implications for immunotherapy

scientific article published on 22 July 2016

Isogeneic comparison of primary and metastatic lung cancer identifies CX3CR1 as a molecular determinant of site-specific metastatic diffusion

scientific article published on 17 May 2012

MTL-CEBPA, a small activating RNA therapeutic up-regulating C/EBP-α, in patients with advanced liver cancer: a first-in-human, multi-centre, open-label, phase I trial

scientific article published on 01 May 2020

Management of Hepatocellular Cancer in the time of SARS-CoV-2

scientific article published on 16 May 2020

Matrix stiffness modulates the activity of MMP-9 and TIMP-1 in hepatic stellate cells to perpetuate fibrosis

scientific article published on 13 May 2019

Melatonin: resetting the clock of cancer progression?

scientific article published on 23 December 2015

Monitoring response to transarterial chemoembolization in hepatocellular carcinoma using 18F-Fluorothymidine Positron Emission Tomography

scientific article published on 08 June 2020

NASH limits anti-tumour surveillance in immunotherapy-treated HCC

scientific article published on 24 March 2021

Neoplastic infiltration of the sphenoid wing: a rare manifestation of metastatic colorectal cancer

scientific article published on 01 December 2011

On-target sorafenib toxicity predicts improved survival in hepatocellular carcinoma: a multi-centre, prospective study.

scientific article

PD-L1 expressing granulomatous reaction as an on-target mechanism of steroid-refractory immune hepatotoxicity

scientific article published on 01 May 2019

PD-L1.

scientific article published on 2 November 2017

Peptide receptor radionuclide therapy for metastatic paragangliomas.

scientific article published on 8 April 2016

Perspectives on the neoadjuvant use of immunotherapy in hepatocellular carcinoma

scientific article published on 28 December 2020

Post-registration experience of nivolumab in advanced hepatocellular carcinoma: an international study

scientific article published on 01 August 2020

Prediction of Survival Among Patients Receiving Transarterial Chemoembolization for Hepatocellular Carcinoma: A Response-Based Approach

scientific article published on 07 November 2019

Preliminary qualification of a novel, hypoxic-based radiologic signature for trans-arterial chemoembolization in hepatocellular carcinoma

scientific article published on 20 February 2018

Presenting Features and Early Mortality from SARS-CoV-2 Infection in Cancer Patients during the Initial Stage of the COVID-19 Pandemic in Europe

scientific article published on 08 July 2020

Prevalence and impact of COVID-19 sequelae on treatment and survival of patients with cancer who recovered from SARS-CoV-2 infection: evidence from the OnCovid retrospective, multicentre registry study

journal article from 'The Lancet Oncology' published in 2021

Prognostic performance of inflammation-based prognostic indices in primary operable non-small cell lung cancer

scientific article published on 25 March 2014

Prognostic sub-classification of intermediate-stage hepatocellular carcinoma: a multicenter cohort study with propensity score analysis

scientific article published on 06 September 2016

Programmed cell death ligands expression drives immune tolerogenesis across the diverse subtypes of neuroendocrine tumours

scientific article published on 25 February 2020

Programmed cell death ligands expression in phaeochromocytomas and paragangliomas: Relationship with the hypoxic response, immune evasion and malignant behavior

scientific article published on 4 August 2017

Programmed death ligand 1 (PD-L1) expression influences the immune-tolerogenic microenvironment in antiretroviral therapy-refractory Kaposi's sarcoma: A pilot study

scientific article published on 7 April 2017

Qualification of tumour mutational burden by targeted next-generation sequencing as a biomarker in hepatocellular carcinoma

scientific article published on 23 October 2020

Recent advances in HIV-associated Kaposi sarcoma

scientific article published on 26 June 2019

Regression of Paraneoplastic Rash after Lung Cancer Chemotherapy

scientific article published on 14 October 2017

Relapse of HHV8-positive multicentric Castleman disease following rituximab-based therapy in HIV-positive patients.

scientific article published on 31 January 2017

Reliability and Reproducibility of the Edmondson Grading of Hepatocellular Carcinoma Using Paired Core Biopsy and Surgical Resection Specimens

scientific article published on December 1, 2010

Reply to: 'Validating the ALBI grade: Its current and future use in HCC prognostication'.

scientific article published on 24 November 2016

Retinoic Acid Receptor-β Is Downregulated in Hepatocellular Carcinoma and Cirrhosis and Its Expression Inhibits Myosin-Driven Activation and Durotaxis in Hepatic Stellate Cells

scientific article published on 17 December 2018

Review article: delivering precision oncology in intermediate-stage liver cancer

scientific article

Shifting paradigms in the systemic management of hepatocellular carcinoma

scientific article published on 01 October 2020

Stereotactic Body Radiation Therapy as an Alternative Treatment for Patients with Hepatocellular Carcinoma Compared to Sorafenib: A Propensity Score Analysis

scientific article published on 12 July 2018

Systemic Inflammatory Response Is a Prognostic Marker in HIV-Infected Patients with Hepatocellular Carcinoma.

scientific article published on 16 September 2017

TAMing resistance to multi-targeted kinase inhibitors through Axl and Met inhibition.

scientific article

The ALBI grade provides objective hepatic reserve estimation across each BCLC stage of hepatocellular carcinoma.

scientific article published on 24 September 2016

The Kings Score refines prognostic prediction in hepatocellular carcinoma: a novel application.

scientific article published on 4 April 2015

The albumin-bilirubin grade improves hepatic reserve estimation post-sorafenib failure: implications for drug development.

scientific article published on 24 January 2017

The albumin-bilirubin grade uncovers the prognostic relationship between hepatic reserve and immune dysfunction in HIV-associated hepatocellular carcinoma.

scientific article

The expression of Axl receptor tyrosine kinase influences the tumour phenotype and clinical outcome of patients with malignant pleural mesothelioma

scientific article published on January 29, 2013

The systemic inflammatory response as a source of biomarkers and therapeutic targets in hepatocellular carcinoma

scientific article published on 18 September 2019

Therapeutic hierarchy in hepatocellular carcinoma: A dispute of evidence versus practice

scientific article published on 01 September 2019

Tissue biomarkers of prognostic significance in hepatocellular carcinoma

scientific article

Treatment Stage Migration Maximizes Survival Outcomes in Patients with Hepatocellular Carcinoma Treated with Sorafenib: An Observational Study

scientific article published on 16 September 2017

Upregulation of C/EBPα Inhibits Suppressive Activity of Myeloid Cells and Potentiates Antitumor Response in Mice and Patients with Cancer

scientific article published on 18 August 2021

Validation of the hepatoma arterial embolization prognostic score in European and Asian populations and proposed modification

scientific article published on 18 December 2014