Search filters

List of works by Aladar A Szalay

A novel genetically modified oncolytic vaccinia virus in experimental models is effective against a wide range of human cancers

scientific article published on 19 January 2012

A novel oncolytic viral therapy and imaging technique for gastric cancer using a genetically engineered vaccinia virus carrying the human sodium iodide symporter

scientific article published on 02 January 2014

A novel recombinant vaccinia virus expressing the human norepinephrine transporter retains oncolytic potential and facilitates deep-tissue imaging.

scientific article published on 25 February 2009

A novel vaccinia virus with dual oncolytic and anti-angiogenic therapeutic effects against triple-negative breast cancer

scientific article

An oncolytic vaccinia virus expressing the human sodium iodine symporter prolongs survival and facilitates SPECT/CT imaging in an orthotopic model of malignant pleural mesothelioma ⬇️

scientific article published on July 23, 2013

Anti-VEGF single-chain antibody GLAF-1 encoded by oncolytic vaccinia virus significantly enhances antitumor therapy

scientific article

Antigen profiling analysis of vaccinia virus injected canine tumors: oncolytic virus efficiency predicted by boolean models

scientific article

Bacterial delivery of functional messenger RNA to mammalian cells

scientific article

Bacterial glucuronidase as general marker for oncolytic virotherapy or other biological therapies ⬇️

scientific article published on October 11, 2011

Biotherapeutic approaches to target cancer stem cells

scientific article published on January 2013

Characterization and evaluation of a new oncolytic Vaccinia Virus strain LIVP6.1.1 for canine cancer therapy ⬇️

scientific article published on October 23, 2012

Characterization of metastasis formation and virotherapy in the human C33A cervical cancer model

scientific article

Cloning and functional study of porcine parotid hormone, a novel proline-rich protein

scientific article published in April 2005

Colonization of experimental murine breast tumours by Escherichia coli K-12 significantly alters the tumour microenvironment

scientific article published on 17 January 2008

Colonization of xenograft tumors by oncolytic vaccinia virus (VACV) results in enhanced tumor killing due to the involvement of myeloid cells

scientific article

Combination immunotherapy with oncolytic vaccinia virus and checkpoint inhibitor following local tumor irradiation

scientific article

Combination of fractionated irradiation with anti‐VEGF expressing vaccinia virus therapy enhances tumor control by simultaneous radiosensitization of tumor associated endothelium ⬇️

scientific article published on August 5, 2013

Combination treatment with oncolytic Vaccinia virus and cyclophosphamide results in synergistic antitumor effects in human lung adenocarcinoma bearing mice

scientific article

Correlates between host and viral transcriptional program associated with different oncolytic vaccinia virus isolates

scientific article

Delivery of oncolytic vaccinia virus by matched allogeneic stem cells overcomes critical innate and adaptive immune barriers

Doxycycline Inducible Melanogenic Vaccinia Virus as Theranostic Anti-Cancer Agent

scientific article published on 15 June 2015

Drug-Encoded Biomarkers for Monitoring Biological Therapies

scientific article

Effective Oncolytic Vaccinia Therapy for Human Sarcomas ⬇️

scientific article published on December 14, 2011

Efficient colonization and therapy of human hepatocellular carcinoma (HCC) using the oncolytic vaccinia virus strain GLV-1h68

scientific article (publication date: 2011)

Enterobacterial tumor colonization in mice depends on bacterial metabolism and macrophages but is independent of chemotaxis and motility

scientific article published on 23 May 2010

Eradication of solid human breast tumors in nude mice with an intravenously injected light-emitting oncolytic vaccinia virus

scientific article

Erratum to: A novel vaccinia virus with dual oncolytic and anti-angiogenic therapeutic effects against triple-negative breast cancer

scientific article

Escherichia coli Nissle 1917 facilitates tumor detection by positron emission tomography and optical imaging

scientific article

Establishment and characterization of conditions required for tumor colonization by intravenously delivered bacteria

scientific article published on June 2008

Evaluation of a new recombinant oncolytic vaccinia virus strain GLV-5b451 for feline mammary carcinoma therapy

scientific article

Expression of anti-VEGF antibody together with anti-EGFR or anti-FAP enhances tumor regression as a result of vaccinia virotherapy

scientific article published on 18 March 2015

Functional hyper-IL-6 from vaccinia virus-colonized tumors triggers platelet formation and helps to alleviate toxicity of mitomycin C enhanced virus therapy

scientific article

Gene therapy using therapeutic and diagnostic recombinant oncolytic vaccinia virus GLV-1h153 for management of colorectal peritoneal carcinomatosis

scientific article

Growth inhibition of different human colorectal cancer xenografts after a single intravenous injection of oncolytic vaccinia virus GLV-1h68 ⬇️

scientific article published on March 26, 2013

Highlights of the society for immunotherapy of cancer (SITC) 27th annual meeting

scientific article published on 29 May 2013

Humanized Mice with Subcutaneous Human Solid Tumors for Immune Response Analysis of Vaccinia Virus-Mediated Oncolysis

scientific article published on 21 March 2017

Imaging a Genetically Engineered Oncolytic Vaccinia Virus (GLV-1h99) Using a Human Norepinephrine Transporter Reporter Gene

scientific article

Imaging characteristics, tissue distribution, and spread of a novel oncolytic vaccinia virus carrying the human sodium iodide symporter

scientific article published in 2012

Imaging of intratumoral inflammation during oncolytic virotherapy of tumors by 19F-magnetic resonance imaging (MRI)

scientific article published on 18 February 2013

Imaging of light emission from the expression of luciferases in living cells and organisms: a review

scientific article

Inducible gene expression in tumors colonized by modified oncolytic vaccinia virus strains

scientific article

Insertion of the human sodium iodide symporter to facilitate deep tissue imaging does not alter oncolytic or replication capability of a novel vaccinia virus

scientific article

Interaction and assembly of murine pre-replicative complex proteins in yeast and mouse cells

scientific article

Intratumoral INF-γ triggers an antiviral state in GL261 tumor cells: a major hurdle to overcome for oncolytic vaccinia virus therapy of cancer

scientific article published on 24 June 2015

Isolated limb perfusion with melphalan, tumour necrosis factor-alpha and oncolytic vaccinia virus improves tumour targeting and prolongs survival in a rat model of advanced extremity sarcoma.

scientific article

Magnetic resonance imaging of tumors colonized with bacterial ferritin-expressing Escherichia coli

scientific article (publication date: 2011)

Microglia and astrocytes attenuate the replication of the oncolytic vaccinia virus LIVP 1.1.1 in murine GL261 gliomas by acting as vaccinia virus traps

scientific article published on 7 July 2015

Molecular network, pathway, and functional analysis of time-dependent gene changes associated with pancreatic cancer susceptibility to oncolytic vaccinia virotherapy

scientific article

Myristoylation negative msbB-mutants of probiotic E. coli Nissle 1917 retain tumor specific colonization properties but show less side effects in immunocompetent mice.

scientific article

Novel oncolytic agent GLV-1h68 is effective against malignant pleural mesothelioma

scientific article

Novel therapy for anaplastic thyroid carcinoma cells using an oncolytic vaccinia virus carrying the human sodium iodide symporter

scientific article

Oncolytic gene therapy with recombinant vaccinia strain GLV-2b372 efficiently kills hepatocellular carcinoma

scientific article published on 3 June 2015

Oncolytic immunotherapy using recombinant vaccinia virus GLV-1h68 kills sorafenib-resistant hepatocellular carcinoma efficiently

scientific article

Oncolytic vaccinia therapy of squamous cell carcinoma

scientific article published on 06 July 2009

Oncolytic vaccinia virotherapy of anaplastic thyroid cancer in vivo

scientific article published on 12 August 2008

Oncolytic vaccinia virus GLV-1h68 strain shows enhanced replication in human breast cancer stem-like cells in comparison to breast cancer cells.

scientific article

Oncolytic vaccinia virus therapy of salivary gland carcinoma

scientific article published on February 2013

Oncolytic virotherapy in veterinary medicine: current status and future prospects for canine patients.

scientific article

Oncolytic virotherapy of canine and feline cancer

scientific article

Oncolytic viruses

scientific article published in 2012

Optical detection and virotherapy of live metastatic tumor cells in body fluids with vaccinia strains

scientific article published in 2013

Optical imaging: bacteria, viruses, and mammalian cells encoding light-emitting proteins reveal the locations of primary tumors and metastases in animals

scientific article

PEG-pHPMAm-based polymeric micelles loaded with doxorubicin-prodrugs in combination antitumor therapy with oncolytic vaccinia viruses.

scientific article

Permissivity of the NCI-60 cancer cell lines to oncolytic Vaccinia Virus GLV-1h68

scientific article

Phase I Trial of Intravenous Oncolytic Vaccinia Virus (GL-ONC1) with Cisplatin and Radiotherapy in Patients with Locoregionally Advanced Head and Neck Carcinoma

scientific article published on 5 July 2017

Preclinical Testing Oncolytic Vaccinia Virus Strain GLV-5b451 Expressing an Anti-VEGF Single-Chain Antibody for Canine Cancer Therapy

scientific article published on 20 July 2015

Preclinical evaluation of oncolytic vaccinia virus for therapy of canine soft tissue sarcoma

scientific article (publication date: 2012)

Preferential Colonization of Metastases by Oncolytic Vaccinia Virus Strain GLV-1h68 in a Human PC-3 Prostate Cancer Model in Nude Mice ⬇️

scientific article published on September 25, 2012

Preferential Replication of Systemically Delivered Oncolytic Vaccinia Virus in Focally Irradiated Glioma Xenografts ⬇️

scientific article published on February 29, 2012

Prodrug converting enzyme gene delivery by L. monocytogenes

scientific article

Real-Time Imaging of Tumors Using Replication-Competent Light-Emitting Microorganisms ⬇️

scientific article published on January 1, 2012

Real-time intraoperative detection of melanoma lymph node metastases using recombinant vaccinia virus GLV-1h68 in an immunocompetent animal model

scientific article published on February 2009

Recombinant vaccinia virus GLV-1h68 is a promising oncolytic vector in the treatment of cholangiocarcinoma

scientific article published on 20 November 2015

Regression of human pancreatic tumor xenografts in mice after a single systemic injection of recombinant vaccinia virus GLV-1h68.

scientific article published on January 2009

Regression of human prostate tumors and metastases in nude mice following treatment with the recombinant oncolytic vaccinia virus GLV-1h68.

scientific article

Replication efficiency of oncolytic vaccinia virus in cell cultures prognosticates the virulence and antitumor efficacy in mice ⬇️

scientific article published on September 27, 2011

Signatures associated with rejection or recurrence in HER-2/neu-positive mammary tumors

scientific article published on April 2008

Significant Growth Inhibition of Canine Mammary Carcinoma Xenografts following Treatment with Oncolytic Vaccinia Virus GLV-1h68.

scientific article

Silk-elastin-like protein polymer matrix for intraoperative delivery of an oncolytic vaccinia virus

scientific article published on 22 September 2014

Single-agent combinatorial cancer therapy ⬇️

scientific article published on May 10, 2013

Systemic treatment of xenografts with vaccinia virus GLV-1h68 reveals the immunologic facet of oncolytic therapy

scientific article published on 7 July 2009

Targeting hematologic malignancies with oncolytic vaccinia virus constructs

scientific article published on 7 November 2013

The highly attenuated oncolytic recombinant vaccinia virus GLV-1h68: comparative genomic features and the contribution of F14.5L inactivation

scientific article published on 22 August 2009

The immunologic aspects of poxvirus oncolytic therapy

scientific article

The ratio of ADSCs to HSC-progenitors in adipose tissue derived SVF may provide the key to predict the outcome of stem-cell therapy

scientific article published on 7 February 2018

Treatment of anaplastic thyroid carcinoma in vitro with a mutant vaccinia virus.

scientific article published on 5 November 2007

Treatment of malignant effusion by oncolytic virotherapy in an experimental subcutaneous xenograft model of lung cancer

scientific article published on May 2013

Tumor-specific colonization, tissue distribution, and gene induction by probiotic Escherichia coli Nissle 1917 in live mice

scientific article published on 19 April 2007

Vaccinia Virus-mediated Expression of Human Erythropoietin in Tumors Enhances Virotherapy and Alleviates Cancer-related Anemia in Mice ⬇️

scientific article published on June 14, 2013

Vaccinia virus GLV-1h153 in combination with 131I shows increased efficiency in treating triple-negative breast cancer

scientific article

Vaccinia virus GLV-1h153 is a novel agent for detection and effective local control of positive surgical margins for breast cancer ⬇️

scientific article published on March 18, 2013

Vaccinia virus GLV-1h153 is effective in treating and preventing metastatic triple-negative breast cancer.

scientific article published on September 2012

Vaccinia virus GLV-1h237 carrying a Walker A motif mutation of mouse Cdc6 protein enhances human breast tumor therapy in mouse xenografts

scientific article published on 18 January 2011

Vaccinia virus expressing bone morphogenetic protein-4 in novel glioblastoma orthotopic models facilitates enhanced tumor regression and long-term survival

scientific article published on 24 June 2013

Vaccinia virus-mediated intra-tumoral expression of matrix metalloproteinase 9 enhances oncolysis of PC-3 xenograft tumors ⬇️

scientific article published on August 23, 2012

Vaccinia virus-mediated melanin production allows MR and optoacoustic deep tissue imaging and laser-induced thermotherapy of cancer

scientific article

Viral-mediated oncolysis is the most critical factor in the late-phase of the tumor regression process upon vaccinia virus infection ⬇️

scientific article published on February 14, 2011

Virotherapy of canine tumors with oncolytic vaccinia virus GLV-1h109 expressing an anti-VEGF single-chain antibody ⬇️

scientific article published on October 16, 2012

Visualization of molecular and cellular events with green fluorescent proteins in developing embryos: a review.

scientific article

Visualization of tumors and metastases in live animals with bacteria and vaccinia virus encoding light-emitting proteins

scientific article

Paulina is supported by:

About Paulina

Help