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List of works by Robert L Martuza

142 Genetic and Nongenetic Determinants of Cellular Architecture in IDH1-Mutant Oligodendrogliomas and Astrocytomas Using Single-Cell Transcriptome Analysis

scientific article published on August 2016

24-year-old woman with an internal auditory canal mass. Hybrid peripheral nerve sheath tumor with schwannoma/perineurioma components

scientific article published in May 2013

A new patient-derived orthotopic malignant meningioma model treated with oncolytic herpes simplex virus.

scientific article published on 6 March 2016

A novel oncolytic herpes simplex virus that synergizes with phosphoinositide 3-kinase/Akt pathway inhibitors to target glioblastoma stem cells. ⬇️

scientific article

AI-21HIF-1A TARGETING IN AN ORTHOTOPIC XENOGRAFT MODEL THAT RECAPITULATES THE HYPOXIC MICROENVIRONMENT OF GLIOBLASTOMA.

scientific article

An aberrant transcription factor network essential for Wnt signaling and stem cell maintenance in glioblastoma.

scientific article published on 23 May 2013

Anesthesia for Suboccipital Craniotomy in a Patient with Lymphangioleiomyomatosis: A Case Report ⬇️

scientific article published on July 29, 2012

Angiogenic response caused by oncolytic herpes simplex virus-induced reduced thrombospondin expression can be prevented by specific viral mutations or by administering a thrombospondin-derived peptide

scientific article published on January 2007

Antiangiogenesis in neurofibromatosis 1.

scientific article

Assessment of therapeutic efficacy and fate of engineered human mesenchymal stem cells for cancer therapy

scholarly article

Bevacizumab with angiostatin-armed oHSV increases antiangiogenesis and decreases bevacizumab-induced invasion in U87 glioma.

scientific article published on 13 September 2011

Blockade of transforming growth factor-β signaling enhances oncolytic herpes simplex virus efficacy in patient-derived recurrent glioblastoma models

scientific article published on 12 August 2017

Brain Tumor Therapy Using Genetically Engineered Replication-Competent Virus

article

CT changes of an intracranial granulocytic sarcoma on short-term follow-up.

scientific article published in January 2003

Circulating growth factor levels are associated with tumorigenesis in neurofibromatosis type 1.

scientific article published in September 2004

Combination immunotherapy for tumors via sequential intratumoral injections of oncolytic herpes simplex virus 1 and immature dendritic cells

scientific article published on December 2008

Combination of oncolytic herpes simplex viruses armed with angiostatin and IL-12 enhances antitumor efficacy in human glioblastoma models.

scientific article published on June 2013

Combinatorial effects of VEGFR kinase inhibitor axitinib and oncolytic virotherapy in mouse and human glioblastoma stem-like cell models.

scientific article published on 29 March 2018

Curing glioblastoma: oncolytic HSV-IL12 and checkpoint blockade

scientific article published on July 2017

Depletion of peripheral macrophages and brain microglia increases brain tumor titers of oncolytic viruses

scientific article

Differential modulation of malignant peripheral nerve sheath tumor growth by omega-3 and omega-6 fatty acids.

scientific article published on March 2005

Distinguishing inflammation from tumor and peritumoral edema by myeloperoxidase magnetic resonance imaging.

scientific article

Dominant-negative fibroblast growth factor receptor expression enhances antitumoral potency of oncolytic herpes simplex virus in neural tumors.

scientific article published on November 2006

Effect of chemotherapy-induced DNA repair on oncolytic herpes simplex viral replication.

scientific article published on January 2006

Effect of γ34.5 Deletions on Oncolytic Herpes Simplex Virus Activity in Brain Tumors ⬇️

scientific article published on February 15, 2012

Effective treatment of tumors with strong beta-catenin/T-cell factor activity by transcriptionally targeted oncolytic herpes simplex virus vector

scientific article published in October 2006

Enhanced antitumor efficacy of low-dose Etoposide with oncolytic herpes simplex virus in human glioblastoma stem cell xenografts

scientific article published on 5 October 2011

Experimental Therapy for Malignant Brain Tumors Using Genetically Engineered Herpes Simplex Virus Type 1

article published in 1996

Expression of FMS-like tyrosine kinase 3 ligand by oncolytic herpes simplex virus type I prolongs survival in mice bearing established syngeneic intracranial malignant glioma

scientific article published on September 2012

Flip-Flop HSV-BAC: bacterial artificial chromosome based system for rapid generation of recombinant herpes simplex virus vectors using two independent site-specific recombinases

scientific article

Genetic determinants of hearing loss associated with vestibular schwannomas

scientific article published in August 2009

Genetically distinct glioma stem-like cell xenografts established from paired glioblastoma samples harvested before and after molecularly targeted therapy

scientific article published in Scientific Reports

Glioblastoma Hypoxia Promotes Oncolytic HSV Replication in vitro and in vivo

Herpes simplex virus Us3(-) mutant as oncolytic strategy and synergizes with phosphatidylinositol 3-kinase-Akt targeting molecular therapeutics.

scientific article

Histopathological prognostic factors of recurrence following definitive therapy for atypical and malignant meningiomas.

scientific article published on 16 June 2017

Human glioblastoma-derived cancer stem cells: establishment of invasive glioma models and treatment with oncolytic herpes simplex virus vectors

scientific article published on 07 April 2009

Hypoxia enhances the replication of oncolytic herpes simplex virus

scientific article

Identification of diagnostic serum protein profiles of glioblastoma patients

scientific article

Identification of the ENT1 antagonists dipyridamole and dilazep as amplifiers of oncolytic herpes simplex virus-1 replication

scientific article

Imaging and extent of surgical resection predict risk of meningioma recurrence better than WHO histopathological grade

scientific article published on 22 November 2015

Long-term recurrence rates of atypical meningiomas after gross total resection with or without postoperative adjuvant radiation

scientific article published on January 2009

MNGO-05IMAGING AND EXTENT OF SURGICAL RESECTION PREDICT RISK OF MENINGIOMA RECURRENCE BETTER THAN WHO HISTOPATHOLOGICAL GRADE.

scientific article

MNGO-16ESTABLISHMENT OF A PATIENT - DERIVED ORTHOTOPIC MALIGNANT MENINGIOMA MODEL FOR THE DEVELOPMENT OF TARGETED THERAPY.

scientific article

Macrophage Polarization Contributes to Glioblastoma Eradication by Combination Immunovirotherapy and Immune Checkpoint Blockade

scientific article published on August 2017

Maintenance of primary tumor phenotype and genotype in glioblastoma stem cells.

scientific article published on 7 November 2011

Multifaceted oncolytic virus therapy for glioblastoma in an immunocompetent cancer stem cell model

scientific article published on 10 June 2013

Multimechanistic tumor targeted oncolytic virus overcomes resistance in brain tumors

scientific article published on 28 August 2012

New frontiers in translational research in neuro-oncology and the blood-brain barrier: report of the tenth annual Blood-Brain Barrier Disruption Consortium Meeting

scientific article

Oncolytic HSV armed with platelet factor 4, an antiangiogenic agent, shows enhanced efficacy.

scientific article published on 10 October 2006

Oncolytic Herpes Simplex Virus Counteracts the Hypoxia-Induced Modulation of Glioblastoma Stem-Like Cells ⬇️

scientific article published on March 21, 2012

Oncolytic Herpes Simplex Virus and PI3K Inhibitor BKM120 Synergize to Promote Killing of Prostate Cancer Stem-like Cells

Oncolytic herpes simplex virus immunovirotherapy in combination with immune checkpoint blockade to treat glioblastoma

scientific article published on 01 July 2018

Oncolytic herpes simplex virus mutants exhibit enhanced replication in glioma cells evading temozolomide chemotherapy through deoxyribonucleic acid repair.

scientific article published on January 2006

Oncolytic herpes simplex virus therapy for peripheral nerve tumors.

scientific article published on 15 June 2007

Oncolytic herpes simplex virus vector g47delta in combination with androgen ablation for the treatment of human prostate adenocarcinoma

scientific article published on November 2005

Oncolytic viral therapies - the clinical experience

scientific article

Oncolytic virus-mediated manipulation of DNA damage responses: synergy with chemotherapy in killing glioblastoma stem cells.

scientific article published on 15 December 2011

Postoperative imaging of vestibular schwannomas

scientific article published on September 2012

Proton beam radiosurgery for vestibular schwannoma: tumor control and cranial nerve toxicity

scientific article published in September 2003

Psychosurgery: past, present, and future

scientific article

RESTRICTION OF γ34.5-DELETED ONCOLYTIC HERPES SIMPLEX VIRUS REPLICATION IN GLIOBLASTOMA STEM-LIKE CELLS.

scientific article

Rad51 Degradation: Role in Oncolytic Virus-Poly(ADP-Ribose) Polymerase Inhibitor Combination Therapy in Glioblastoma

scientific article published on March 2017

Ras signaling influences permissiveness of malignant peripheral nerve sheath tumor cells to oncolytic herpes

scientific article

Reconstructing and reprogramming the tumor-propagating potential of glioblastoma stem-like cells

scientific article published on 10 April 2014

STEM-22LARGE-SCALE SINGLE-CELL RNA-seq REVEALS A DEVELOPMENTAL CELLULAR HIERARCHY IN HUMAN OLIGODENDROGLIOMA.

scientific article

Single agent efficacy of the VEGFR kinase inhibitor axitinib in preclinical models of glioblastoma

scientific article published on 12 September 2014

Single-cell RNA-seq highlights intratumoral heterogeneity in primary glioblastoma

scientific article

Single-cell RNA-seq supports a developmental hierarchy in human oligodendroglioma

scientific article published on 2 November 2016

Somatic mitochondrial DNA mutations in neurofibromatosis type 1-associated tumors

scientific article published on 01 August 2004

Stereotactic radiotherapy for vestibular schwannomas: favorable outcome with minimal toxicity

scientific article published on 01 July 2005

Systemic oncolytic herpes virus therapy of poorly immunogenic prostate cancer metastatic to lung

scientific article published on May 2006

Systemic therapy of spontaneous prostate cancer in transgenic mice with oncolytic herpes simplex viruses

scientific article published in October 2007

Targeting Hypoxia-Inducible Factor 1α in a New Orthotopic Model of Glioblastoma Recapitulating the Hypoxic Tumor Microenvironment

scientific article published on July 2015

The added value of concurrently administered temozolomide versus adjuvant temozolomide alone in newly diagnosed glioblastoma

scientific article published on 30 January 2008

Therapeutic Efficacy of G207 in a Novel Peripheral Nerve Sheath Tumor Model

Transient fasting enhances replication of oncolytic herpes simplex virus in glioblastoma

scientific article published on 15 January 2016

Treatment of Schwannomas with an Oncolytic Recombinant Herpes Simplex Virus in Murine Models of Neurofibromatosis Type 2

Treatment of orthotopic malignant peripheral nerve sheath tumors with oncolytic herpes simplex virus.

scientific article

Treatment of schwannomas with an oncolytic recombinant herpes simplex virus in murine models of neurofibromatosis type 2.

scientific article

Trichostatin A and oncolytic HSV combination therapy shows enhanced antitumoral and antiangiogenic effects

scientific article published on April 2008

Triple gene-deleted oncolytic herpes simplex virus vector double-armed with interleukin 18 and soluble B7-1 constructed by bacterial artificial chromosome-mediated system

scientific article

Vestibular schwannoma

scientific article published in October 2006

Vestibular schwannoma: suboccipital approach

scientific article published in January 2014

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