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List of works by Keun Il Kim

A lignan induces lysosomal dependent degradation of FoxM1 protein to suppress β-catenin nuclear translocation

scientific article published on 05 April 2017

A method for assaying deubiquitinating enzymes

scientific article published on July 20, 1998

A novel adipokine CTRP1 stimulates aldosterone production

scientific article

Adipocyte culture medium stimulates production of macrophage inhibitory cytokine 1 in MDA-MB-231 cells.

scientific article published on 27 December 2007

Adiponectin is a negative regulator of NK cell cytotoxicity.

scientific article

Adiponectin-activated AMPK stimulates dephosphorylation of AKT through protein phosphatase 2A activation.

scientific article published on 14 April 2009

Anti-cancerous effect of cis-khellactone from Angelica amurensis through the induction of three programmed cell deaths.

scientific article published on 30 March 2018

Ascorbate (vitamin C) induces cell death through the apoptosis-inducing factor in human breast cancer cells

scientific article published on October 2007

Bcl3-dependent stabilization of CtBP1 is crucial for the inhibition of apoptosis and tumor progression in breast cancer

scientific article published on August 26, 2010

Bone morphogenetic protein-4 induced by NDRG2 expression inhibits MMP-9 activity in breast cancer cells.

scientific article

Carabrol suppresses LPS-induced nitric oxide synthase expression by inactivation of p38 and JNK via inhibition of I-kappaBalpha degradation in RAW 264.7 cells

scientific article published on 22 December 2009

DNA damage-induced RORα is crucial for p53 stabilization and increased apoptosis

scientific article

Dephosphorylation of CCAAT/enhancer-binding protein β by protein phosphatase 2A containing B56δ is required at the early time of adipogenesis.

scientific article published on 23 August 2014

Distinct regulatory effect of the p34SEI-1 oncoprotein on cancer metastasis in HER2/neu-positive and -negative cells.

scientific article published on 28 April 2014

EZH2 generates a methyl degron that is recognized by the DCAF1/DDB1/CUL4 E3 ubiquitin ligase complex

scientific article

Elevated Response to Type I IFN Enhances RANKL-Mediated Osteoclastogenesis in Usp18-Knockout Mice.

scientific article published on 25 March 2016

Elevation of intracellular cyclic AMP inhibits NF-kappaB-mediated thymosin beta4 expression in melanoma cells

scientific article published on 03 June 2009

Emerging roles of orphan nuclear receptors in cancer

scientific article

Endothelial to Mesenchymal Transition in Pulmonary Vascular Diseases

scientific article published on 21 December 2020

Enhanced antibacterial potential in UBP43-deficient mice against Salmonella typhimurium infection by up-regulating type I IFN signaling

scientific article published in July 2005

Enhanced antitumor activity of vitamin C via p53 in cancer cells.

scientific article

Epigenetic Control of Autophagy: Nuclear Events Gain More Attention

scientific article published on March 2017

Epigenetic and transcriptional regulation of autophagy

scientific article published on 3 August 2016

Epigenetic regulation of the potential tumor suppressor gene, hLHX6.1, in human cervical cancer

scientific article published on 14 January 2011

Expression of human NDRG2 by myeloid dendritic cells inhibits down-regulation of activated leukocyte cell adhesion molecule (ALCAM) and contributes to maintenance of T cell stimulatory activity.

scientific article

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

article by Daniel J Klionsky et al published January 2021 in Autophagy

High-throughput immunoblotting. Ubiquitiin-like protein ISG15 modifies key regulators of signal transduction

scientific article

IK-guided PP2A suppresses Aurora B activity in the interphase of tumor cells

scientific article

ISG15 modification of filamin B negatively regulates the type I interferon-induced JNK signalling pathway

scientific article

ISG15 modification of ubiquitin E2 Ubc13 disrupts its ability to form thioester bond with ubiquitin

scientific article

ISG15, not just another ubiquitin-like protein

scientific article

Identification of the KAI1 metastasis suppressor gene as a hypoxia target gene.

scientific article

Increase in CIP2A expression is associated with doxorubicin resistance.

scientific article published on 18 January 2011

Increased expression of the F(1)F(o) ATP synthase in response to iron in heart mitochondria

scientific article

Inhibition of LSD1 phosphorylation alleviates colitis symptoms induced by dextran sulfate sodium

scientific article published on 22 April 2020

Inhibition of autophagy sensitizes lignan-induced endoplasmic reticulum stress-mediated cell death

scientific article published on 21 March 2020

Inhibitory role of TRIP-Br1 oncoprotein in hypoxia-induced apoptosis in breast cancer cell lines.

scientific article published on 24 March 2016

Integrated analysis of transcriptomes of cancer cell lines and patient samples reveals STK11/LKB1-driven regulation of cAMP phosphodiesterase-4D.

scientific article published on 13 August 2014

Interferon-inducible ubiquitin E2, Ubc8, is a conjugating enzyme for protein ISGylation

scientific article

Klotho inhibits the capacity of cell migration and invasion in cervical cancer

scientific article

Microarray analysis reveals that Type I interferon strongly increases the expression of immune-response related genes in Ubp43 (Usp18) deficient macrophages

scientific article published on 28 February 2007

Mitosis-specific phosphorylation of Mis18α by Aurora B kinase enhances kinetochore recruitment of polo-like kinase 1.

scientific article published on 27 November 2017

Negative regulation of hypoxic responses via induced Reptin methylation.

scientific article

Nuclear receptors and coregulators in inflammation and cancer

scientific article published on 22 April 2008

Nutrient/serum starvation derived TRIP-Br3 down-regulation accelerates apoptosis by destabilizing XIAP.

scientific article published on April 2015

Oncogenic function of p34SEI-1 via NEDD4‑1‑mediated PTEN ubiquitination/degradation and activation of the PI3K/AKT pathway

scientific article published on 20 August 2013

Optimization and biological evaluation of 2-aminobenzothiazole derivatives as Aurora B kinase inhibitors

scientific article published on 6 April 2017

PKCα-LSD1-NF-κB-Signaling Cascade Is Crucial for Epigenetic Control of the Inflammatory Response

scientific article

Pontin-deficiency causes senescence in fibroblast cells and epidermal keratinocytes but induces apoptosis in cancer cells

scientific article published on 14 May 2020

Protein ISGylation modulates the JAK-STAT signaling pathway

scientific article

Purification and Characterization of Protease Ci, a Cytoplasmic Metalloendoprotease in Escherichia coli

scientific article published in 1995

RORalpha attenuates Wnt/beta-catenin signaling by PKCalpha-dependent phosphorylation in colon cancer

scientific article

RORα controls hepatic lipid homeostasis via negative regulation of PPARγ transcriptional network.

scientific article

RORα2 requires LSD1 to enhance tumor progression in breast cancer.

scientific article published on 20 September 2017

Regulation of HIF-1α stability by lysine methylation

scientific article published on 14 March 2016

Regulation of mIκBNS stability through PEST-mediated degradation by proteasome.

scientific article published on 6 January 2014

Role of ISG15 protease UBP43 (USP18) in innate immunity to viral infection.

scientific article

Roles of Mis18α in epigenetic regulation of centromeric chromatin and CENP-A loading

scientific journal article

Roles of sumoylation of a reptin chromatin-remodelling complex in cancer metastasis

scientific article

SIAH1-induced p34SEI-1 polyubiquitination/degradation mediates p53 preferential vitamin C cytotoxicity.

scientific article published on 13 January 2015

SK-126, a synthetic compound, regulates the production of inflammatory cytokines induced by LPS in antigen-presenting cells

scientific article published on 4 November 2007

SOCS1 induced by NDRG2 expression negatively regulates STAT3 activation in breast cancer cells.

scientific article published on 14 September 2007

SUMO-specific protease SUSP4 positively regulates p53 by promoting Mdm2 self-ubiquitination

scientific article published on 5 November 2006

SUMOylation code in cancer development and metastasis.

scientific article published on December 2006

SUMOylation of RORalpha potentiates transcriptional activation function.

scientific article published on 28 November 2008

SUMOylation of pontin chromatin-remodeling complex reveals a signal integration code in prostate cancer cells

scientific article published on 26 December 2007

Serum starvation induces G1 arrest through suppression of Skp2-CDK2 and CDK4 in SK-OV-3 cells

scientific article published on February 2008

Skin-Specific Deletion of Mis18α Impedes Proliferation and Stratification of Epidermal Keratinocytes

scientific article

Small ubiquitin-like modifiers in cellular malignancy and metastasis

scientific article published on January 2009

TRIP-Br1 oncoprotein inhibits autophagy, apoptosis, and necroptosis under nutrient/serum-deprived condition.

scientific article published on 21 August 2015

The anti-aging gene KLOTHO is a novel target for epigenetic silencing in human cervical carcinoma

scientific article

The mitochondrial pathway and reactive oxygen species are critical contributors to interferon-α/β-mediated apoptosis in Ubp43-deficient hematopoietic cells.

scientific article

The role of ADCYAP1, adenylate cyclase activating polypeptide 1, as a methylation biomarker for the early detection of cervical cancer

scientific article published in January 2011

Tumor necrosis factor-alpha and interleukin-1beta increases CTRP1 expression in adipose tissue.

scientific article

UBP43 (USP18) specifically removes ISG15 from conjugated proteins

scientific article

UBP43 is a novel regulator of interferon signaling independent of its ISG15 isopeptidase activity

scientific article

ULK1 O-GlcNAcylation Is Crucial for Activating VPS34 via ATG14L during Autophagy Initiation

scientific article published on 01 December 2018

Ube1L and protein ISGylation are not essential for alpha/beta interferon signaling

scientific article

Versatile protein tag, SUMO: its enzymology and biological function

scientific article

βTrCP-mediated ubiquitylation regulates protein stability of Mis18β in a cell cycle-dependent manner.

scientific article published on 21 November 2013