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List of works by Linda A Fothergill-Gilmore

A new family of covalent inhibitors block nucleotide binding to the active site of pyruvate kinase.

scientific article

Allosteric Mechanism of Pyruvate Kinase from Leishmania mexicana Uses a Rock and Lock Model

scientific article

An allostatic mechanism for M2 pyruvate kinase as an amino-acid sensor.

scientific article published on 31 May 2018

An improved strategy for the crystallization ofLeishmania mexicanapyruvate kinase

scientific article

Crystal structures of Leishmania mexicana phosphoglycerate mutase suggest a one-metal mechanism and a new enzyme subclass

scientific article

Design, synthesis and trypanocidal activity of lead compounds based on inhibitors of parasite glycolysis

scientific article

Expression, purification, crystallization and preliminary crystallographic analysis of Leishmania mexicana phosphoglycerate mutase

scientific article published on 27 June 2003

Identification of ML251, a Potent Inhibitor of T. brucei and T. cruzi Phosphofructokinase

scientific article

Phosphoglycerate mutase from Trypanosoma brucei is hyperactivated by cobalt in vitro, but not in vivo

scientific article published on 13 October 2011

Pyruvate kinases have an intrinsic and conserved decarboxylase activity

scientific article

Structures of pyruvate kinases display evolutionarily divergent allosteric strategies

scientific article

The Trypanocidal Drug Suramin and Other Trypan Blue Mimetics Are Inhibitors of Pyruvate Kinases and Bind to the Adenosine Site

scientific article

The crystal structure of ATP-bound phosphofructokinase from Trypanosoma brucei reveals conformational transitions different from those of other phosphofructokinases

scientific article

The first crystal structure of phosphofructokinase from a eukaryote: Trypanosoma brucei

scientific article

`In crystallo' substrate binding triggers major domain movements and reveals magnesium as a co-activator of Trypanosoma brucei pyruvate kinase

scientific article

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