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List of works by Janet L Stein

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Canonical WNT Signaling Promotes Osteogenesis by Directly StimulatingRunx2Gene Expression

scientific article published in Journal of Biological Chemistry
Biological functions of miR-29b contribute to positive regulation of osteoblast differentiation

scientific article published on 02 April 2009
A microRNA signature for a BMP2-induced osteoblast lineage commitment program

scientific article
Networks and hubs for the transcriptional control of osteoblastogenesis.

scientific article published on June 2006
Self-renewal of human embryonic stem cells is supported by a shortened G1 cell cycle phase

scientific article published on December 2006
Regulatory controls for osteoblast growth and differentiation: role of Runx/Cbfa/AML factors

scientific article
MicroRNA control of bone formation and homeostasis

scientific article published on 31 January 2012
A program of microRNAs controls osteogenic lineage progression by targeting transcription factor Runx2

scientific journal article
Tyrosine phosphorylation controls Runx2-mediated subnuclear targeting of YAP to repress transcription

scientific article published on 12 February 2004
Runx2 control of organization, assembly and activity of the regulatory machinery for skeletal gene expression

scientific article published on May 2004
A network connecting Runx2, SATB2, and the miR-23a~27a~24-2 cluster regulates the osteoblast differentiation program

scientific article
MicroRNAs 221 and 222 bypass quiescence and compromise cell survival

scientific article
The Runx2 osteogenic transcription factor regulates matrix metalloproteinase 9 in bone metastatic cancer cells and controls cell invasion

scientific article
Mitotic occupancy and lineage-specific transcriptional control of rRNA genes by Runx2.

scientific article
Dlx3 transcriptional regulation of osteoblast differentiation: temporal recruitment of Msx2, Dlx3, and Dlx5 homeodomain proteins to chromatin of the osteocalcin gene.

scientific article published on October 2004
miR-218 directs a Wnt signaling circuit to promote differentiation of osteoblasts and osteomimicry of metastatic cancer cells

scientific article
The bone-specific expression of Runx2 oscillates during the cell cycle to support a G1-related antiproliferative function in osteoblasts

scientific article
CCAAT/enhancer-binding proteins (C/EBP) beta and delta activate osteocalcin gene transcription and synergize with Runx2 at the C/EBP element to regulate bone-specific expression.

scientific article published on 19 October 2001
Cell growth regulatory role of Runx2 during proliferative expansion of preosteoblasts

scientific article published on September 1, 2003
BMP2 commitment to the osteogenic lineage involves activation of Runx2 by DLX3 and a homeodomain transcriptional network.

scientific article published on 23 October 2006
Runx2 transcriptional activation of Indian Hedgehog and a downstream bone metastatic pathway in breast cancer cells

scientific article published on October 2008
Structural coupling of Smad and Runx2 for execution of the BMP2 osteogenic signal.

scientific article
Impaired intranuclear trafficking of Runx2 (AML3/CBFA1) transcription factors in breast cancer cells inhibits osteolysis in vivo.

scientific article
Regulation of the bone-specific osteocalcin gene by p300 requires Runx2/Cbfa1 and the vitamin D3 receptor but not p300 intrinsic histone acetyltransferase activity

scientific journal article
Nuclear microenvironments in biological control and cancer.

scientific article published on June 2007
Mitotic retention of gene expression patterns by the cell fate-determining transcription factor Runx2.

scholarly article
Integration of Runx and Smad regulatory signals at transcriptionally active subnuclear sites

scientific article
Dicer inactivation in osteoprogenitor cells compromises fetal survival and bone formation, while excision in differentiated osteoblasts increases bone mass in the adult mouse

scientific article
Survival responses of human embryonic stem cells to DNA damage

scientific article
Mitotic bookmarking of genes: a novel dimension to epigenetic control.

scientific article
HOXA10 controls osteoblastogenesis by directly activating bone regulatory and phenotypic genes.

scientific article published on 26 February 2007
Targeting of Runx2 by miR-135 and miR-203 Impairs Progression of Breast Cancer and Metastatic Bone Disease

scientific article
High-resolution molecular validation of self-renewal and spontaneous differentiation in clinical-grade adipose-tissue derived human mesenchymal stem cells.

scientific article
Phenotype discovery by gene expression profiling: mapping of biological processes linked to BMP-2-mediated osteoblast differentiation

scientific article
Runx2 regulates G protein-coupled signaling pathways to control growth of osteoblast progenitors

scientific article
Smad function and intranuclear targeting share a Runx2 motif required for osteogenic lineage induction and BMP2 responsive transcription.

scientific article
Chromatin interaction analysis reveals changes in small chromosome and telomere clustering between epithelial and breast cancer cells

scientific article
HiNF-P directly links the cyclin E/CDK2/p220NPAT pathway to histone H4 gene regulation at the G1/S phase cell cycle transition.

scientific article
Altered Runx1 subnuclear targeting enhances myeloid cell proliferation and blocks differentiation by activating a miR-24/MKP-7/MAPK network

scientific article
Control of mesenchymal lineage progression by microRNAs targeting skeletal gene regulators Trps1 and Runx2.

scientific article
Functional architecture of the nucleus: organizing the regulatory machinery for gene expression, replication and repair.

scientific article published on November 2003
Phenotypic transcription factors epigenetically mediate cell growth control.

scholarly article
Runx2 deficiency and defective subnuclear targeting bypass senescence to promote immortalization and tumorigenic potential.

scholarly article
The dynamic organization of gene-regulatory machinery in nuclear microenvironments

scientific article
A Runx2 threshold for the cleidocranial dysplasia phenotype

scientific article
Overlapping expression of Runx1(Cbfa2) and Runx2(Cbfa1) transcription factors supports cooperative induction of skeletal development

scientific journal article
Establishment of histone gene regulation and cell cycle checkpoint control in human embryonic stem cells

scientific article published in February 2007
Ectopic runx2 expression in mammary epithelial cells disrupts formation of normal acini structure: implications for breast cancer progression

scientific article published on 18 August 2009
Bone-specific transcription factor Runx2 interacts with the 1alpha,25-dihydroxyvitamin D3 receptor to up-regulate rat osteocalcin gene expression in osteoblastic cells

scientific journal article
Staged assembly of histone gene expression machinery at subnuclear foci in the abbreviated cell cycle of human embryonic stem cells

scholarly article

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