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List of works by Janet L Stein

1alpha,25-dihydroxy vitamin D(3) induces nuclear matrix association of the 1alpha,25-dihydroxy vitamin D(3) receptor in osteoblasts independently of its ability to bind DNA

scientific article

1alpha,25-dihydroxy vitamin D3-enhanced expression of the osteocalcin gene involves increased promoter occupancy of basal transcription regulators and gradual recruitment of the 1alpha,25-dihydroxy vitamin D3 receptor-SRC-1 coactivator complex

scientific journal article

A RUNX2-HDAC1 co-repressor complex regulates rRNA gene expression by modulating UBF acetylation

scientific article

A Runx2 threshold for the cleidocranial dysplasia phenotype

scientific article

A functional N-terminal domain in C/EBPβ-LAP* is required for interacting with SWI/SNF and to repress Ric-8B gene transcription in osteoblasts

scientific article

A germline point mutation in Runx1 uncouples its role in definitive hematopoiesis from differentiation

scientific article published on 30 June 2013

A microRNA signature for a BMP2-induced osteoblast lineage commitment program

scientific article

A network connecting Runx2, SATB2, and the miR-23a~27a~24-2 cluster regulates the osteoblast differentiation program

scientific article

A program of microRNAs controls osteogenic lineage progression by targeting transcription factor Runx2

scientific journal article

Activation of the bone-related Runx2/Cbfa1 promoter in mesenchymal condensations and developing chondrocytes of the axial skeleton

scientific article published in June 2002

Alterations in intranuclear localization of Runx2 affect biological activity

scientific article published on December 2006

Altered Runx1 subnuclear targeting enhances myeloid cell proliferation and blocks differentiation by activating a miR-24/MKP-7/MAPK network

scientific article

Altered chromatin modifications in AML1/RUNX1 breakpoint regions involved in (8;21) translocation.

scientific article published in February 2009

An architectural genetic and epigenetic perspective

scientific article published on 24 December 2010

An architectural perspective of cell-cycle control at the G1/S phase cell-cycle transition.

scientific article published on December 2006

An architectural perspective of vitamin D responsiveness.

scientific article published on 8 January 2007

Analysis of in vivo gene expression using epitope-tagged proteins

scientific article published on 01 January 2004

Antagonizing miR-218-5p attenuates Wnt signaling and reduces metastatic bone disease of triple negative breast cancer cells

scientific article published on 12 October 2016

Architectural epigenetics: mitotic retention of mammalian transcriptional regulatory information

scientific article

Architectural genetic and epigenetic control of regulatory networks: compartmentalizing machinery for transcription and chromatin remodeling in nuclear microenvironments

scientific article

BMP2 commitment to the osteogenic lineage involves activation of Runx2 by DLX3 and a homeodomain transcriptional network.

scientific article published on 23 October 2006

Biological functions of miR-29b contribute to positive regulation of osteoblast differentiation

scientific article published on 02 April 2009

Bone-specific transcription factor Runx2 interacts with the 1alpha,25-dihydroxyvitamin D3 receptor to up-regulate rat osteocalcin gene expression in osteoblastic cells

scientific journal article

Bookmarking target genes in mitosis: a shared epigenetic trait of phenotypic transcription factors and oncogenes?

scientific article published on 09 January 2014

Bookmarking the genome: maintenance of epigenetic information.

scientific article

Brg1, the ATPase subunit of the SWI/SNF chromatin remodeling complex, is required for myeloid differentiation to granulocytes

scientific article published on January 2006

C/EBPβ binds the P1 promoter of the Runx2 gene and up-regulates Runx2 transcription in osteoblastic cells

scientific article published on November 2011

CBFβ and the leukemogenic fusion protein CBFβ-SMMHC associate with mitotic chromosomes to epigenetically regulate ribosomal genes

scientific article

CCAAT/enhancer-binding proteins (C/EBP) beta and delta activate osteocalcin gene transcription and synergize with Runx2 at the C/EBP element to regulate bone-specific expression.

scientific article published on 19 October 2001

CDK inhibitors selectively diminish cell cycle controlled activation of the histone H4 gene promoter by p220NPAT and HiNF-P

scientific article

Canonical WNT Signaling Promotes Osteogenesis by Directly StimulatingRunx2Gene Expression

scientific article published in Journal of Biological Chemistry

Cell cycle dependent phosphorylation and subnuclear organization of the histone gene regulator p220(NPAT) in human embryonic stem cells.

scientific article published on October 2007

Cell cycle related modulations in Runx2 protein levels are independent of lymphocyte enhancer-binding factor 1 (Lef1) in proliferating osteoblasts

scientific article published on 21 September 2007

Cell growth regulatory role of Runx2 during proliferative expansion of preosteoblasts ⬇️

scientific article published on September 1, 2003

Chromatin dynamics regulate mesenchymal stem cell lineage specification and differentiation to osteogenesis

scientific article published on 8 January 2017

Chromatin immunoprecipitation

scientific article published on 01 January 2004

Chromatin immunoprecipitation assays: application of ChIP-on-chip for defining dynamic transcriptional mechanisms in bone cells.

scientific article

Chromatin interaction analysis reveals changes in small chromosome and telomere clustering between epithelial and breast cancer cells

scientific article

Chromatin remodeling and transcriptional activity of the bone-specific osteocalcin gene require CCAAT/enhancer-binding protein beta-dependent recruitment of SWI/SNF activity

scientific article

Chromatin remodeling by SWI/SNF results in nucleosome mobilization to preferential positions in the rat osteocalcin gene promoter

scientific article published on February 2007

Co-stimulation of the bone-related Runx2 P1 promoter in mesenchymal cells by SP1 and ETS transcription factors at polymorphic purine-rich DNA sequences (Y-repeats)

scientific article

Combinatorial organization of the transcriptional regulatory machinery in biological control and cancer

scientific article

Control of mesenchymal lineage progression by microRNAs targeting skeletal gene regulators Trps1 and Runx2.

scientific article

Coordinate control and selective expression of the full complement of replication-dependent histone H4 genes in normal and cancer cells

scientific article published on 29 August 2005

Core binding factor β (CBFβ) is retained in the midbody during cytokinesis

scientific article

Cyclin D2 and the CDK substrate p220(NPAT) are required for self-renewal of human embryonic stem cells

scientific article

Definitive hematopoiesis requires Runx1 C-terminal-mediated subnuclear targeting and transactivation.

scientific article

Dicer inactivation in osteoprogenitor cells compromises fetal survival and bone formation, while excision in differentiated osteoblasts increases bone mass in the adult mouse

scientific article

Differential gene expression analysis using paraffin-embedded tissues after laser microdissection

scientific article published in December 2003

Dlx3 transcriptional regulation of osteoblast differentiation: temporal recruitment of Msx2, Dlx3, and Dlx5 homeodomain proteins to chromatin of the osteocalcin gene.

scientific article published on October 2004

Ectopic runx2 expression in mammary epithelial cells disrupts formation of normal acini structure: implications for breast cancer progression

scientific article published on 18 August 2009

Epigenetic Control of the Bone-master Runx2 Gene during Osteoblast-lineage Commitment by the Histone Demethylase JARID1B/KDM5B.

scientific article published on 9 October 2015

Epigenetic control of cell cycle-dependent histone gene expression is a principal component of the abbreviated pluripotent cell cycle.

scientific article

Epigenetic mechanisms in leukemia

scientific article published on 24 May 2012

Epigenetic regulation of early osteogenesis and mineralized tissue formation by a HOXA10-PBX1-associated complex

scientific article

Epithelial-to-mesenchymal transition and cancer stem cells contribute to breast cancer heterogeneity

scientific article published on 03 July 2018

Establishment of histone gene regulation and cell cycle checkpoint control in human embryonic stem cells

scientific article published in February 2007

Ethyl acetate and n-butanol fraction of Cissus quadrangularis promotes the mineralization potential of murine pre-osteoblast cell line MC3T3-E1 (sub-clone 4)

scientific article published on 15 November 2018

Expression of Runx2 transcription factor in non-skeletal tissues, sperm and brain

scientific article

Ezh2-dependent H3K27me3 modification dynamically regulates vitamin D3-dependent epigenetic control of CYP24A1 gene expression in osteoblastic cells

scientific article published on 07 January 2020

Fidelity of histone gene regulation is obligatory for genome replication and stability

scientific article

Forced expression of the interferon regulatory factor 2 oncoprotein causes polyploidy and cell death in FDC-P1 myeloid hematopoietic progenitor cells

scientific article

Four novel RUNX2 mutations including a splice donor site result in the cleidocranial dysplasia phenotype.

scientific article published in April 2006

Functional architecture of the nucleus: organizing the regulatory machinery for gene expression, replication and repair.

scientific article published on November 2003

Functional characterization of a human histone gene cluster duplication

scientific article

Functional coupling of transcription factor HiNF-P and histone H4 gene expression during pre- and post-natal mouse development.

scientific article

Gene profiling of cell cycle progression through S-phase reveals sequential expression of genes required for DNA replication and nucleosome assembly

scientific article

Genetic ablation of the CDP/Cux protein C terminus results in hair cycle defects and reduced male fertility

scientific journal article

Genetic and epigenetic regulation in nuclear microenvironments for biological control in cancer

scientific article published on August 2008

Genome-wide co-occupancy of AML1-ETO and N-CoR defines the t(8;21) AML signature in leukemic cells

scientific article published on 17 April 2015

Genomic occupancy of HLH, AP1 and Runx2 motifs within a nuclease sensitive site of the Runx2 gene

scientific article published on February 2013

Genomic occupancy of Runx2 with global expression profiling identifies a novel dimension to control of osteoblastogenesis.

scientific article published on 21 March 2014

Genomic promoter occupancy of runt-related transcription factor RUNX2 in Osteosarcoma cells identifies genes involved in cell adhesion and motility

scientific article published on 9 December 2011

HOXA10 controls osteoblastogenesis by directly activating bone regulatory and phenotypic genes.

scientific article published on 26 February 2007

HiNF-P directly links the cyclin E/CDK2/p220NPAT pathway to histone H4 gene regulation at the G1/S phase cell cycle transition.

scientific article

HiNF-P is a bifunctional regulator of cell cycle controlled histone H4 gene transcription

scientific article

High-resolution molecular validation of self-renewal and spontaneous differentiation in clinical-grade adipose-tissue derived human mesenchymal stem cells.

scientific article

Higher order genomic organization and regulatory compartmentalization for cell cycle control at the G1/S-phase transition

scientific article published on 10 May 2018

Histone acetylation in vivo at the osteocalcin locus is functionally linked to vitamin D-dependent, bone tissue-specific transcription

scientific article

Human embryonic stem cells are pre-mitotically committed to self-renewal and acquire a lengthened G1 phase upon lineage programming

scientific article

Identification of novel protein/DNA interactions within the promoter of the bone-related transcription factor Runx2/Cbfa1.

scientific article published on January 2002

Identification of tRNA-derived small RNA (tsRNA) responsive to the tumor suppressor, RUNX1, in breast cancer

scientific article published on 10 January 2020

Identifying Nuclear Matrix-Attached DNA Across the Genome

scientific article published on 14 September 2016

Immunofluorescence analysis using epitope-tagged proteins: in vitro system

scientific article published on 01 January 2004

Impaired cell cycle regulation of the osteoblast-related heterodimeric transcription factor Runx2-Cbfbeta in osteosarcoma cells

scientific article

Impaired intranuclear trafficking of Runx2 (AML3/CBFA1) transcription factors in breast cancer cells inhibits osteolysis in vivo.

scientific article

In situ immunofluorescence analysis: analyzing RNA synthesis by 5-bromouridine-5'-triphosphate labeling

scientific article

In situ immunofluorescence analysis: immunofluorescence microscopy

scientific article published on 01 January 2004

In situ nuclear organization of regulatory machinery

scientific article published on 01 January 2008

Integration of Runx and Smad regulatory signals at transcriptionally active subnuclear sites

scientific article

Interaction of the 1alpha,25-dihydroxyvitamin D3 receptor at the distal promoter region of the bone-specific osteocalcin gene requires nucleosomal remodelling

scientific journal article

Intranuclear Trafficking: Organization and Assembly of Regulatory Machinery for Combinatorial Biological Control

scientific article (publication date: 23 July 2004)

Intranuclear and higher-order chromatin organization of the major histone gene cluster in breast cancer.

scientific article

Intranuclear organization of RUNX transcriptional regulatory machinery in biological control of skeletogenesis and cancer

scientific article

Intranuclear trafficking of transcription factors: Requirements for vitamin D-mediated biological control of gene expression.

scientific article

Intricate gene regulatory networks of helix-loop-helix (HLH) proteins support regulation of bone-tissue related genes during osteoblast differentiation

scientific article published on October 2008

Live cell imaging of the cancer-related transcription factor RUNX2 during mitotic progression

scientific article

Maintenance of open chromatin and selective genomic occupancy at the cell cycle-regulated histone H4 promoter during differentiation of HL-60 promyelocytic leukemia cells

scientific article

Maternal expression and early induction of histone gene transcription factor Hinfp sustains development in pre-implantation embryos

scientific article

MicroRNA control of bone formation and homeostasis

scientific article published on 31 January 2012

MicroRNA-34c inversely couples the biological functions of the runt-related transcription factor RUNX2 and the tumor suppressor p53 in osteosarcoma

scientific article published on 29 May 2013

MicroRNAs 221 and 222 bypass quiescence and compromise cell survival

scientific article

Microtubule-dependent nuclear-cytoplasmic shuttling of Runx2.

scientific article published on February 2006

Mitotic bookmarking of genes: a novel dimension to epigenetic control.

scientific article

Mitotic control of RUNX2 phosphorylation by both CDK1/cyclin B kinase and PP1/PP2A phosphatase in osteoblastic cells

scientific article published on April 2007

Mitotic occupancy and lineage-specific transcriptional control of rRNA genes by Runx2.

scientific article

Mitotic partitioning and selective reorganization of tissue-specific transcription factors in progeny cells

scientific journal article

Mitotic retention of gene expression patterns by the cell fate-determining transcription factor Runx2.

scholarly article

Mll-COMPASS complexes mediate H3K4me3 enrichment and transcription of the osteoblast master gene Runx2/p57 in osteoblasts

scientific article published on 07 September 2018

Molecular switches involving homeodomain proteins, HOXA10 and RUNX2 regulate osteoblastogenesis

scientific article published on 14 August 2008

Multiple levels of epigenetic control for bone biology and pathology

scientific article

Multiple subnuclear targeting signals of the leukemia-related AML1/ETO and ETO repressor proteins

scientific article

Networks and hubs for the transcriptional control of osteoblastogenesis.

scientific article published on June 2006

Nkx3.2-mediated repression of Runx2 promotes chondrogenic differentiation

scientific journal article

Nuclear microenvironments in biological control and cancer.

scientific article published on June 2007

Nuclear microenvironments support assembly and organization of the transcriptional regulatory machinery for cell proliferation and differentiation

scientific article published on February 2004

Nuclear microenvironments support physiological control of gene expression

scientific article published in January 2003

Nucleosome organization and targeting of SWI/SNF chromatin-remodeling complexes: contributions of the DNA sequence

scientific article published on August 2007

Oncogenic cooperation between PI3K/Akt signaling and transcription factor Runx2 promotes the invasive properties of metastatic breast cancer cells

scientific article published on August 2013

Organization of transcriptional regulatory machinery in nuclear microenvironments: implications for biological control and cancer

scientific article published on 23 March 2007

Organization of transcriptional regulatory machinery in osteoclast nuclei: compartmentalization of Runx1.

scientific article published in September 2005

Organization, integration, and assembly of genetic and epigenetic regulatory machinery in nuclear microenvironments: implications for biological control in cancer

scientific article published on February 2009

Overlapping expression of Runx1(Cbfa2) and Runx2(Cbfa1) transcription factors supports cooperative induction of skeletal development

scientific journal article

Pbx1 represses osteoblastogenesis by blocking Hoxa10-mediated recruitment of chromatin remodeling factors

scientific article

Phenotype discovery by gene expression profiling: mapping of biological processes linked to BMP-2-mediated osteoblast differentiation

scientific article

Phenotypic transcription factors epigenetically mediate cell growth control.

scholarly article

Phosphorylation at serine 208 of the 1alpha,25-dihydroxy Vitamin D3 receptor modulates the interaction with transcriptional coactivators

scientific article published on March 2007

Point mutation in AML1 disrupts subnuclear targeting, prevents myeloid differentiation, and effects a transformation-like phenotype.

scientific article

Primary mouse embryonic fibroblasts: A model of mesenchymal cartilage formation

article

Prostate cancer regulatory networks

scientific article

Protein-deoxyribonucleic acid interactions linked to gene expression: DNase I digestion.

scientific article published on January 2004

Protein-deoxyribonucleic acid interactions linked to gene expression: electrophoretic mobility shift assay

scientific article published on 01 January 2004

Protein-deoxyribonucleic acid interactions linked to gene expression: ligation-mediated polymerase chain reaction

scientific article published on 01 January 2004

Quantitative signature for architectural organization of regulatory factors using intranuclear informatics.

scientific article published on 14 September 2004

RUNX1 and RUNX2 transcription factors function in opposing roles to regulate breast cancer stem cells

scientific article published on 17 March 2020

RUNX1 contributes to higher-order chromatin organization and gene regulation in breast cancer cells.

scientific article published on 8 August 2016

RUNX1-dependent mechanisms in biological control and dysregulation in cancer

scientific article published on 04 December 2018

Real-time detection of breast cancer at the cellular level

scientific article published on 26 October 2018

Reconstitution of Runx2/Cbfa1-null cells identifies a requirement for BMP2 signaling through a Runx2 functional domain during osteoblast differentiation

scientific article published on February 2007

Recruitment and subnuclear distribution of the regulatory machinery during 1alpha,25-dihydroxy vitamin D3-mediated transcriptional upregulation in osteoblasts

scientific article

Reduced CpG methylation is associated with transcriptional activation of the bone-specific rat osteocalcin gene in osteoblasts

scientific article

Regulation of osteogenesis by long noncoding RNAs: An epigenetic mechanism contributing to bone formation

scientific article published on 01 December 2018

Regulation of the bone-specific osteocalcin gene by p300 requires Runx2/Cbfa1 and the vitamin D3 receptor but not p300 intrinsic histone acetyltransferase activity

scientific journal article

Regulatory controls for osteoblast growth and differentiation: role of Runx/Cbfa/AML factors

scientific article

Reprogramming the pluripotent cell cycle: restoration of an abbreviated G1 phase in human induced pluripotent stem (iPS) cells

scientific article

Ribonucleoprotein immunoprecipitation (RNP-IP): a direct in vivo analysis of microRNA-targets

scientific article published in July 2010

Runx1 Activities in Superficial Zone Chondrocytes, Osteoarthritic Chondrocyte Clones and Response to Mechanical Loading

scientific article published on February 2015

Runx1 is associated with breast cancer progression in MMTV-PyMT transgenic mice and its depletion in vitro inhibits migration and invasion

scientific article published on October 2015

Runx2 control of organization, assembly and activity of the regulatory machinery for skeletal gene expression

scientific article published on May 2004

Runx2 deficiency and defective subnuclear targeting bypass senescence to promote immortalization and tumorigenic potential.

scholarly article

Runx2 protein expression utilizes the Runx2 P1 promoter to establish osteoprogenitor cell number for normal bone formation

scientific article

Runx2 regulates G protein-coupled signaling pathways to control growth of osteoblast progenitors

scientific article

Runx2 transcriptional activation of Indian Hedgehog and a downstream bone metastatic pathway in breast cancer cells

scientific article published on October 2008

Runx2/Cbfa1 functions: diverse regulation of gene transcription by chromatin remodeling and co-regulatory protein interactions

scientific article

SMARCA4 regulates gene expression and higher-order chromatin structure in proliferating mammary epithelial cells

scientific article published on 19 July 2016

SWI/SNF chromatin remodeling complex is obligatory for BMP2-induced, Runx2-dependent skeletal gene expression that controls osteoblast differentiation

scientific journal article

SWI/SNF-independent nuclease hypersensitivity and an increased level of histone acetylation at the P1 promoter accompany active transcription of the bone master gene Runx2.

scientific article published on August 2009

Self-renewal of human embryonic stem cells is supported by a shortened G1 cell cycle phase

scientific article published on December 2006

Smad function and intranuclear targeting share a Runx2 motif required for osteogenic lineage induction and BMP2 responsive transcription.

scientific article

Specific residues of RUNX2 are obligatory for formation of BMP2-induced RUNX2-SMAD complex to promote osteoblast differentiation.

scientific article published on 26 August 2008

Staged assembly of histone gene expression machinery at subnuclear foci in the abbreviated cell cycle of human embryonic stem cells

scholarly article

Structural coupling of Smad and Runx2 for execution of the BMP2 osteogenic signal.

scientific article

Subnuclear domain proteins in cancer cells support the functions of RUNX2 in the DNA damage response

scientific article

Subnuclear localization and intranuclear trafficking of transcription factors

scientific article published on January 2010

Subnuclear targeting of Runx1 is required for synergistic activation of the myeloid specific M-CSF receptor promoter by PU.1.

scientific article published on November 2005

Subnuclear targeting of the Runx3 tumor suppressor and its epigenetic association with mitotic chromosomes.

scientific article

Suppression of Breast Cancer Stem Cells and Tumor Growth by the RUNX1 Transcription Factor

scientific article published on 06 August 2018

Survival responses of human embryonic stem cells to DNA damage

scientific article

Switches in histone modifications epigenetically control vitamin D3-dependent transcriptional upregulation of the CYP24A1 gene in osteoblastic cells

scientific article published on 23 December 2019

Targeting of Runx2 by miR-135 and miR-203 Impairs Progression of Breast Cancer and Metastatic Bone Disease

scientific article

The 1alpha,25-dihydroxy Vitamin D3 receptor preferentially recruits the coactivator SRC-1 during up-regulation of the osteocalcin gene

scientific article

The BRG1 chromatin remodeling enzyme links cancer cell metabolism and proliferation

scientific article

The HiNF-P/p220NPAT cell cycle signaling pathway controls nonhistone target genes

scientific article

The Notch-responsive transcription factor Hes-1 attenuates osteocalcin promoter activity in osteoblastic cells

scientific journal article

The Runx2 osteogenic transcription factor regulates matrix metalloproteinase 9 in bone metastatic cancer cells and controls cell invasion

scientific article

The Runx2 transcription factor plays a key role in the 1alpha,25-dihydroxy Vitamin D3-dependent upregulation of the rat osteocalcin (OC) gene expression in osteoblastic cells

scientific article published in May 2004

The SWI/SNF ATPases Are Required for Triple Negative Breast Cancer Cell Proliferation

scientific article

The architectural organization of human stem cell cycle regulatory machinery

scientific journal article

The bone-related Zn finger transcription factor Osterix promotes proliferation of mesenchymal cells

scientific article

The bone-specific expression of Runx2 oscillates during the cell cycle to support a G1-related antiproliferative function in osteoblasts

scientific article

The cancer-related Runx2 protein enhances cell growth and responses to androgen and TGFbeta in prostate cancer cells.

scientific article

The classic receptor for 1alpha,25-dihydroxy vitamin D3 is required for non-genomic actions of 1alpha,25-dihydroxy vitamin D3 in osteosarcoma cells

scientific article published on 01 November 2006

The cleidocranial dysplasia-related R131G mutation in the Runt-related transcription factor RUNX2 disrupts binding to DNA but not CBF-beta

scientific article

The dynamic architectural and epigenetic nuclear landscape: developing the genomic almanac of biology and disease.

scientific article published on June 2014

The dynamic organization of gene-regulatory machinery in nuclear microenvironments

scientific article

The gene for aromatase, a rate-limiting enzyme for local estrogen biosynthesis, is a downstream target gene of Runx2 in skeletal tissues

scientific article

The histone deacetylase inhibitor, vorinostat, reduces tumor growth at the metastatic bone site and associated osteolysis, but promotes normal bone loss

scientific article

The histone gene activator HINFP is a nonredundant cyclin E/CDK2 effector during early embryonic cell cycles

scientific journal article

The histone gene cell cycle regulator HiNF-P is a unique zinc finger transcription factor with a novel conserved auxiliary DNA-binding motif

scientific article

The histone gene transcription factor HiNF-P stabilizes its cell cycle regulatory co-activator p220NPAT.

scientific article published on December 2006

The human SWI/SNF complex associates with RUNX1 to control transcription of hematopoietic target genes

scientific article

The interactome of the histone gene regulatory factor HiNF-P suggests novel cell cycle related roles in transcriptional control and RNA processing

scientific article

The leukemogenic t(8;21) fusion protein AML1-ETO controls rRNA genes and associates with nucleolar-organizing regions at mitotic chromosomes.

scientific article

The osteogenic transcription factor Runx2 regulates components of the fibroblast growth factor/proteoglycan signaling axis in osteoblasts

scientific article

The osteogenic transcription factor runx2 controls genes involved in sterol/steroid metabolism, including CYP11A1 in osteoblasts

scientific article published on 02 April 2009

The subnuclear organization of histone gene regulatory proteins and 3' end processing factors of normal somatic and embryonic stem cells is compromised in selected human cancer cell types

scientific article

The tumor suppressor interferon regulatory factor 1 interferes with SP1 activation to repress the human CDK2 promoter

scientific article published on 5 May 2003

The vitamin D response element in the distal osteocalcin promoter contributes to chromatin organization of the proximal regulatory domain

scientific article

Transcription factor-mediated epigenetic regulation of cell growth and phenotype for biological control and cancer

scientific article

Transcription-factor-mediated epigenetic control of cell fate and lineage commitment

scientific article published on February 2009

Transcriptional activation of the histone nuclear factor P (HiNF-P) gene by HiNF-P and its cyclin E/CDK2 responsive co-factor p220NPAT defines a novel autoregulatory loop at the G1/S phase transition

scientific article

Transcriptional corepressor TLE1 functions with Runx2 in epigenetic repression of ribosomal RNA genes

scientific article

Tyrosine phosphorylation controls Runx2-mediated subnuclear targeting of YAP to repress transcription

scientific article published on 12 February 2004

Vitamin D control of gene expression: temporal and spatial parameters for organization of the regulatory machinery

scientific article published on January 2008

hsa-mir-30c promotes the invasive phenotype of metastatic breast cancer cells by targeting NOV/CCN3.

scientific article

miR-218 directs a Wnt signaling circuit to promote differentiation of osteoblasts and osteomimicry of metastatic cancer cells

scientific article

microRNA-mediated survivin control of pluripotency

scientific article

p53 checkpoint ablation exacerbates the phenotype of Hinfp dependent histone H4 deficiency

scientific article

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