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List of works by Derek C Radisky

93rd Annual Meeting of the American Association for Cancer Research, San Francisco, CA, USA, 6-10 April 2002

scientific article

A Soft Microenvironment Protects from Failure of Midbody Abscission and Multinucleation Downstream of the EMT-Promoting Transcription Factor Snail

scientific article published on 26 February 2018

Activation of PI3K/Akt/mTOR signaling in the tumor stroma drives endocrine therapy-dependent breast tumor regression

scientific article

Alterations in the Immune Cell Composition in Premalignant Breast Tissue that Precede Breast Cancer Development

scientific article published on 26 January 2017

Association between mammographic breast density and histologic features of benign breast disease

scientific article published on 19 December 2017

Association between mammographic density and age-related lobular involution of the breast.

scientific article

Benign Breast Disease and the Risk of Subsequent Breast Cancer in African American Women ⬇️

scientific article published on October 19, 2012

Bioinformatics and DNA-extraction strategies to reliably detect genetic variants from FFPE breast tissue samples

scientific article published on 02 September 2019

Breast Cancer Risk and Progressive Histology in Serial Benign Biopsies

scientific article

Breast Cancer Risk and Use of Non-steroidal Anti-inflammatory Agents After a Benign Breast Biopsy

scientific article published on 27 July 2020

Breast cancer risk by the extent and type of atypical hyperplasia

scientific article published on 28 June 2016

CD56+ immune cell infiltration and MICA are decreased in breast lobules with fibrocystic changes.

scientific article published in November 2017

Cancer. Respect thy neighbor!

scientific article published in February 2004

Change in cell shape is required for matrix metalloproteinase-induced epithelial-mesenchymal transition of mammary epithelial cells

scientific article

Clinical characteristics of breast cancers in African-American women with benign breast disease: a comparison to the surveillance, epidemiology, and end results program

scientific article

Clinicopathologic features of breast cancers that develop in women with previous benign breast disease.

scientific article published on 29 October 2015

Combinatorial protein engineering of proteolytically resistant mesotrypsin inhibitors as candidates for cancer therapy

scientific article

Complex fibroadenoma and breast cancer risk: a Mayo Clinic Benign Breast Disease Cohort Study

scientific article

Cytotoxic T cell depletion with increasing epithelial abnormality in women with benign breast disease

scientific article published on 13 January 2020

Delivering the message: epimorphin and mammary epithelial morphogenesis

scientific article

EGFR as a prognostic biomarker and therapeutic target in ovarian cancer: evaluation of patient cohort and literature review

scientific article

ERβ expression and breast cancer risk prediction for women with atypias

scientific article

Effective Targeting of Estrogen Receptor-Negative Breast Cancers with the Protein Kinase D Inhibitor CRT0066101.

scientific article published on 7 April 2015

Enhanced antitumor immunity via endocrine therapy prevents mammary tumor relapse and increases immune checkpoint blockade sensitivity

scientific article published on 02 December 2020

Epimorphin Is a Novel Regulator of the Progesterone Receptor Isoform-A ⬇️

scientific article published on July 18, 2013

Epimorphin acts to induce hair follicle anagen in C57BL/6 mice

scientific article published in November 2003

Epithelial-mesenchymal transition: general principles and pathological relevance with special emphasis on the role of matrix metalloproteinases

scientific article published on February 2012

Estrogen receptor expression in atypical hyperplasia: lack of association with breast cancer

scientific article

Evaluation of 2 breast cancer risk models in a benign breast disease cohort

scientific article published on 22 June 2018

Extent of atypical hyperplasia stratifies breast cancer risk in 2 independent cohorts of women

scientific article published on 28 June 2016

Extracellular localization of epimorphin/syntaxin-2.

scientific article published on October 2007

Fibrosis and cancer: do myofibroblasts come also from epithelial cells via EMT?

scientific article

Flat epithelial atypia and risk of breast cancer: A Mayo cohort study

scientific article published on 13 January 2015

Gene signature model for breast cancer risk prediction for women with sclerosing adenosis.

scientific article published on 23 July 2015

Histologic findings in normal breast tissues: comparison to reduction mammaplasty and benign breast disease tissues

scientific article published on September 2011

Homology with vesicle fusion mediator syntaxin-1a predicts determinants of epimorphin/syntaxin-2 function in mammary epithelial morphogenesis

scientific article published on 07 January 2009

Hyaline fibrous involution of breast lobules: a histologic finding associated with germline BRCA mutation

scientific article published on 17 April 2019

Identifying the Stroma as a Critical Player in Radiation-Induced Mammary Tumor Development ⬇️

scientific article published on May 17, 2011

Immune Responses and Risk of Triple Negative Breast Cancer: Implications for Higher Rates among African American women

scientific article published on 04 August 2020

Immune cell quantitation in normal breast tissue lobules with and without lobulitis.

scientific article published on 05 March 2014

Immune promotion of epithelial-mesenchymal transition and generation of breast cancer stem cells.

scientific article

Immune-induced epithelial to mesenchymal transition in vivo generates breast cancer stem cells

scientific article

Involvement of hnRNP A1 in the matrix metalloprotease-3-dependent regulation of Rac1 pre-mRNA splicing.

scientific article published on July 2012

Ki-67 expression in sclerosing adenosis and adjacent normal breast terminal ductal lobular units: a nested case-control study from the Mayo Benign Breast Disease Cohort

scientific article published on 12 April 2015

Laminin and biomimetic extracellular elasticity enhance functional differentiation in mammary epithelia

scientific article published on 09 October 2008

Lobular involution: localized phenomenon or field effect?

scientific article

MYC Is a Crucial Mediator of TGFβ-Induced Invasion in Basal Breast Cancer

scientific article published on 13 April 2016

MYC suppresses cancer metastasis by direct transcriptional silencing of αv and β3 integrin subunits

scientific article

Macrophagic "crown-like structures" are associated with an increased risk of breast cancer in benign breast disease

scientific article published on 22 November 2017

Malignant mammary cells acquire independence from extracellular context for regulation of estrogen receptor alpha

scientific article published on January 2004

Mammary involution and breast cancer risk: transgenic models and clinical studies

scientific article published on 30 April 2009

Mammographic breast density and risk of breast cancer in women with atypical hyperplasia: an observational cohort study from the Mayo Clinic Benign Breast Disease (BBD) cohort

scientific article

Matrix Metalloproteinase-10 (MMP-10) Interaction with Tissue Inhibitors of Metalloproteinases TIMP-1 and TIMP-2: BINDING STUDIES AND CRYSTAL STRUCTURE

scientific article

Matrix metalloproteinase-induced genomic instability

scientific article

Mechanism of Akt1 inhibition of breast cancer cell invasion reveals a protumorigenic role for TSC2.

scholarly article

Mechanisms of disease: epithelial-mesenchymal transition--does cellular plasticity fuel neoplastic progression?

scientific article

Mesotrypsin promotes malignant growth of breast cancer cells through shedding of CD109

scientific article

Microenvironmental Influences that Drive Progression from Benign Breast Disease to Invasive Breast Cancer ⬇️

scientific article published on December 16, 2010

Model for Predicting Breast Cancer Risk in Women With Atypical Hyperplasia

scientific article published on 20 April 2018

Model for individualized prediction of breast cancer risk after a benign breast biopsy

scientific article

NF-kappaB links oestrogen receptor signalling and EMT

scientific article published on 01 April 2007

NanoString-based breast cancer risk prediction for women with sclerosing adenosis

scientific article published on 10 August 2017

Natural history of age-related lobular involution and impact on breast cancer risk

scientific article published on 4 February 2016

Non-classical export of epimorphin and its adhesion to alphav-integrin in regulation of epithelial morphogenesis

scientific article published on 29 May 2007

Novel breast tissue feature strongly associated with risk of breast cancer

scientific article published on 05 October 2009

PRSS3/Mesotrypsin Is a Therapeutic Target for Metastatic Prostate Cancer ⬇️

scientific article published on December 1, 2012

Polarity and proliferation are controlled by distinct signaling pathways downstream of PI3-kinase in breast epithelial tumor cells

scientific article

Postlactational involution biomarkers plasminogen and phospho-STAT3 are linked with active age-related lobular involution.

scientific article published on 27 July 2017

Proliferation and polarity in breast cancer: untying the Gordian knot

scientific article

Protein kinase D1 drives pancreatic acinar cell reprogramming and progression to intraepithelial neoplasia

scientific article

Pseudoangiomatous stromal hyperplasia and breast cancer risk

scientific article

ROS-induced epithelial-mesenchymal transition in mammary epithelial cells is mediated by NF-kB-dependent activation of Snail

scientific article

Regulation of epithelial-mesenchymal transition in breast cancer cells by cell contact and adhesion

scientific article published on 9 February 2015

Regulation of mechanical stress by mammary epithelial tissue structure controls breast cancer cell invasion ⬇️

scientific article published on April 1, 2013

Sclerosing adenosis and risk of breast cancer.

scientific article published on 08 February 2014

Serine protease inhibitor Kazal type 1 (SPINK1) drives proliferation and anoikis resistance in a subset of ovarian cancers

scientific article published on 30 September 2015

Single proteins might have dual but related functions in intracellular and extracellular microenvironments

scientific article published on 04 February 2009

Snail1, Snail2, and E47 promote mammary epithelial branching morphogenesis ⬇️

scientific article published on May 24, 2011

TGFβ/TNFα-Mediated Epithelial–Mesenchymal Transition Generates Breast Cancer Stem Cells with a Claudin-Low Phenotype ⬇️

scientific article published on May 9, 2011

The 19-amino acid insertion in the tumor-associated splice isoform Rac1b confers specific binding to p120 catenin

scientific article

The Microbiome of Aseptically Collected Human Breast Tissue in Benign and Malignant Disease

scientific article published on 03 August 2016

The P 2 ′ residue is a key determinant of mesotrypsin specificity: engineering a high-affinity inhibitor with anticancer activity

scientific article

The organizing principle: microenvironmental influences in the normal and malignant breast

scientific article

Therapeutic Potential of Matrix Metalloproteinase Inhibition in Breast Cancer

scientific article published on 6 June 2017

Tissue Stiffness and Hypoxia Modulate the Integrin-Linked Kinase ILK to Control Breast Cancer Stem-like Cells

scientific article published on 8 August 2016

Tissue composition of mammographically dense and non-dense breast tissue ⬇️

scientific article published on August 30, 2011

Tumor cell-derived MMP3 orchestrates Rac1b and tissue alterations that promote pancreatic adenocarcinoma

scientific article

Tumor cell-produced matrix metalloproteinase 9 (MMP-9) drives malignant progression and metastasis of basal-like triple negative breast cancer

scientific article

Understanding the premalignant potential of atypical hyperplasia through its natural history: a longitudinal cohort study

scientific article

p16(INK4a) expression and breast cancer risk in women with atypical hyperplasia

scientific article published on 15 September 2011

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