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List of works by Randall J Basaraba

2-aminoimidazoles collapse mycobacterial proton motive force and block the electron transport chain

scientific article published in Scientific Reports

2-aminoimidazoles potentiate ß-lactam antimicrobial activity against Mycobacterium tuberculosis by reducing ß-lactamase secretion and increasing cell envelope permeability.

scientific article

A Toll-Like Receptor-2-Directed Fusion Protein Vaccine against Tuberculosis.

scientific article

A Toll-like receptor-2-directed fusion protein vaccine against tuberculosis

scientific article published on July 2007

A model of type 2 diabetes in the guinea pig using sequential diet-induced glucose intolerance and streptozotocin treatment

scientific article published on 12 January 2017

A mouse model of pulmonary Mycobacteroides abscessus infection

scientific article published on 28 February 2020

A mutant of Mycobacterium tuberculosis lacking the 19-kDa lipoprotein Rv3763 is highly attenuated in vivo but retains potent vaccinogenic properties

scientific article published on 13 August 2007

Actin enhances the haemolytic activity of Escherichia coli ⬇️

scientific article published on July 1, 1998

Actin polymerization enhances Pasteurella haemolytica leukotoxicity

scientific article published on 01 February 1999

Activities of TMC207, rifampin, and pyrazinamide against Mycobacterium tuberculosis infection in guinea pigs

scientific article

Alternative BCG delivery strategies improve protection against Mycobacterium tuberculosis in non-human primates: Protection associated with mycobacterial antigen-specific CD4 effector memory T-cell populations ⬇️

scientific article published on 08 October 2016

An Ovarian Teratoma in a Cat ⬇️

scientific article published on 01 March 1998

An aerosol challenge model of tuberculosis in Mauritian cynomolgus macaques ⬇️

scientific article

Analogue synthesis reveals decoupling of antibiofilm and β-lactam potentiation activities of a lead 2-aminoimidazole adjuvant against Mycobacterium smegmatis.

scientific article published on 16 April 2018

Animal model of Mycobacterium abscessus lung infection

scientific article

Antitumor activity of novel tricyclic pyrone analogs in murine leukemia cells in vitro

scientific article published on 01 July 1997

Assessment of necropsy findings in sled dogs that died during Iditarod Trail sled dog races: 23 cases (1994-2006)

scientific article published on 01 February 2008

Azithromycin blocks autophagy and may predispose cystic fibrosis patients to mycobacterial infection.

scientific article

Beijing sublineages of Mycobacterium tuberculosis differ in pathogenicity in the guinea pig.

scientific article

Bilateral Horner's syndrome secondary to metastatic squamous cell carcinoma in a horse

scientific article published on 01 November 1996

Cell-to-cell contact not soluble factors mediate suppression of lymphocyte proliferation by bovine parainfluenza virus type 3.

scientific article

Cigarette smoke increases susceptibility to tuberculosis--evidence from in vivo and in vitro models

scientific article published on 28 February 2011

Clinical strains of Mycobacterium tuberculosis display a wide range of virulence in guinea pigs

scientific article

Comparison of serologic and protective responses induced by two Pasteurella vaccines ⬇️

scientific article published on July 1, 1998

Copper resistance is essential for virulence of Mycobacterium tuberculosis

scientific article

Copper-boosting compounds: a novel concept for antimycobacterial drug discovery

scientific article published on 17 December 2012

Correction: Mycobacterium tuberculosis Universal Stress Protein Rv2623 Regulates Bacillary Growth by ATP-Binding: Requirement for Establishing Chronic Persistent Infection

scientific article published on 16 September 2009

Cyclin-Dependent Kinases 8 and 19 Regulate Host Cell Metabolism during Dengue Virus Serotype 2 Infection

scientific article published on 17 June 2020

Decreased survival of guinea pigs infected with Mycobacterium tuberculosis after multiple BCG vaccinations

scientific article published on 24 August 2005

Defined tuberculosis vaccine, Mtb72F/AS02A, evidence of protection in cynomolgus monkeys

scholarly article

Defining a research agenda to address the converging epidemics of tuberculosis and diabetes. Part 1: Epidemiology and clinical management

scientific article

Defining a research agenda to address the converging epidemics of tuberculosis and diabetes. Part 2: Underlying biological mechanisms

scientific article

Determination of lesion volume by MRI and stereology in a macaque model of tuberculosis.

scientific article

Dietary retinol inhibits inflammatory responses of rats treated with monocrotaline

scientific article published on 01 July 1999

Disseminated disease severity as a measure of virulence of Mycobacterium tuberculosis in the guinea pig model

scientific article published on 05 March 2008

Drug treatment combined with BCG vaccination reduces disease reactivation in guinea pigs infected with Mycobacterium tuberculosis

scientific article published on 11 January 2012

Early lesions following aerosol infection of rhesus macaques (Macaca mulatta) with Mycobacterium tuberculosis strain H37RV.

scientific article

Effect of furosemide on pulmonary blood flow distribution in resting and exercising horses

scientific article published on 01 June 1999

Enhanced priming of adaptive immunity by a proapoptotic mutant of Mycobacterium tuberculosis

scientific article published in August 2007

Establishment of an aerosol challenge model of tuberculosis in rhesus macaques and an evaluation of endpoints for vaccine testing

scientific article

Evaluation of a mouse model of necrotic granuloma formation using C3HeB/FeJ mice for testing of drugs against Mycobacterium tuberculosis

scientific article

Evaluation of standard chemotherapy in the guinea pig model of tuberculosis

scientific article

Evidence for Oxidative Stress and Defective Antioxidant Response in Guinea Pigs with Tuberculosis ⬇️

scientific article published on October 18, 2011

Experimental tuberculosis: the role of comparative pathology in the discovery of improved tuberculosis treatment strategies

scientific article published on August 2008

Expression of antimicrobial drug tolerance by attached communities of Mycobacterium tuberculosis

scientific article

Factors associated with severe granulomatous pneumonia in Mycobacterium tuberculosis-infected mice vaccinated therapeutically with hsp65 DNA.

scientific article

Flexible low-cost system for small animal aerosol inhalation exposure to drugs, proteins, inflammatory agents, and infectious agents

scientific article

Florid pulmonary inflammatory responses in mice vaccinated with Antigen-85 pulsed dendritic cells and challenged by aerosol with Mycobacterium tuberculosis

scientific article published in November 2002

Functional drug screening reveals anticonvulsants as enhancers of mTOR-independent autophagic killing of Mycobacterium tuberculosis through inositol depletion.

scientific article

GM-CSF knockout mice for preclinical testing of agents with antimicrobial activity against Mycobacterium abscessus.

scientific article published on 11 November 2013

Globoid cell-like leukodystrophy in a domestic longhaired cat.

scientific article

Hepatotoxicity of stanozolol in cats

scientific article published on 01 September 2000

High mobility group box 1 acts as an adjuvant for tuberculosis subunit vaccines

scientific article published on May 2014

Host-directed therapy targeting the Mycobacterium tuberculosis granuloma: a review

scientific article published on 28 October 2015

Human IL-32 expression protects mice against a hypervirulent strain of Mycobacterium tuberculosis

scientific article published on 27 March 2015

Hyperpolarized krypton-83 as a contrast agent for magnetic resonance imaging

scientific article

Immune Responses of HIV-1 Tat Transgenic Mice to Mycobacterium Tuberculosis W-Beijing SA161.

scientific article

Immune response to Mycobacterium tuberculosis and identification of molecular markers of disease.

scientific article published on 11 September 2008

Immunopathogenesis of pulmonary granulomas in the guinea pig after infection with Mycobacterium tuberculosis

scientific article

Impaired capillary hemodynamics in skeletal muscle of rats in chronic heart failure

scientific article published on 01 August 1999

In vivo adaptation of the Wayne model of latent tuberculosis

scientific article published on 5 February 2007

Increased Foxp3 expression in guinea pigs infected with W-Beijing strains of M. tuberculosis

scientific article

Increased expression of host iron-binding proteins precedes iron accumulation and calcification of primary lung lesions in experimental tuberculosis in the guinea pig

scientific article

Increased neutrophil influx but no impairment of protective immunity to tuberculosis in mice lacking the CD44 molecule

scientific article

Increased severity of tuberculosis in Guinea pigs with type 2 diabetes: a model of diabetes-tuberculosis comorbidity

scientific article

Infectious Bovine Rhinotracheitis, Parainfluenza-3, and Respiratory Coronavirus ⬇️

scientific article published on November 1, 1997

Influence of Mycobacterium bovis BCG vaccination on cellular immune response of guinea pigs challenged with Mycobacterium tuberculosis

scientific article published on 28 May 2008

Influence of endurance exercise on serum concentrations of iron and acute phase proteins in racing sled dogs ⬇️

scientific article published on 01 November 2011

Inhibition and breaking of advanced glycation end-products (AGEs) with bis-2-aminoimidazole derivatives

scientific article published on January 2015

Interleukin-10 production by lung macrophages in CBA xid mutant mice infected with Mycobacterium tuberculosis

scientific article published on 01 June 2005

Interstitial nephritis in cats inoculated with Crandell Rees feline kidney cell lysates

scientific article

Investigation of the induction of antibodies against Crandell-Rees feline kidney cell lysates and feline renal cell lysates after parenteral administration of vaccines against feline viral rhinotracheitis, calicivirus, and panleukopenia in cats

scientific article

Limited tuberculosis progression in guinea pigs naturally exposed to human multidrug resistant strains

abstract published in 2009

Localized immunosuppressive environment in the foreign body response to implanted biomaterials

scientific article published on 15 June 2009

Location of Intra- and Extracellular M. tuberculosis Populations in Lungs of Mice and Guinea Pigs during Disease Progression and after Drug Treatment ⬇️

scientific article published on March 21, 2011

Location of persisting mycobacteria in a Guinea pig model of tuberculosis revealed by r207910.

scientific article

Lymphadenitis as a major element of disease in the guinea pig model of tuberculosis

scientific article published on 10 February 2006

Magnetic resonance imaging of pulmonary lesions in guinea pigs infected with Mycobacterium tuberculosis

scientific article published on October 2004

Mast cell tumors in three ferrets.

scientific article

Maxillary lymphosarcoma in a cow.

scientific article

Memory T lymphocytes generated by Mycobacterium bovis BCG vaccination reside within a CD4 CD44lo CD62 ligand(hi) population

scientific article

Metabolic Profiling of Lung Granuloma in Mycobacterium tuberculosis Infected Guinea Pigs: Ex vivo 1H Magic Angle Spinning NMR Studies ⬇️

scientific article published on July 26, 2011

Metabolomic signatures in guinea pigs infected with epidemic-associated W-Beijing strains of Mycobacterium tuberculosis

scientific article published on 30 August 2012

Metformin enhances anti-mycobacterial responses by educating CD8+ T-cell immunometabolic circuits

scientific article published on 16 October 2020

Metformin enhances protection in guinea pigs chronically infected with Mycobacterium tuberculosis

scientific article published on 01 October 2020

Metronidazole lacks antibacterial activity in guinea pigs infected with Mycobacterium tuberculosis

scientific article published on 11 August 2008

Microhemorrhage is an early event in the pulmonary fibrotic disease of PECAM-1 deficient FVB/n mice

scientific article published on 24 June 2014

Minimal redistribution of pulmonary blood flow with exercise in racehorses

scientific article published on 01 September 1996

Mucosal expression of aquaporin 5 and epithelial barrier proteins in chronic rhinosinusitis with and without nasal polyps.

scientific article published on 7 December 2013

Multimodality topical therapy for refractory chronic rhinosinusitis: Our experience in thirteen patients with and twelve patients without nasal polyps ⬇️

scientific article published on June 1, 2013

Multiple M. tuberculosis phenotypes in mouse and guinea pig lung tissue revealed by a dual-staining approach

scientific article published in 2010

Mycobacteria lacking the RD1 region do not induce necrosis in the lungs of mice lacking interferon-gamma.

scientific article published in October 2006

Mycobacterial Biofilms: Revisiting Tuberculosis Bacilli in Extracellular Necrotizing Lesions

scientific article published in June 2017

Mycobacterium bovis BCG-mediated protection against W-Beijing strains of Mycobacterium tuberculosis is diminished concomitant with the emergence of regulatory T cells

scientific article

Mycobacterium tuberculosis Lsr2 is a global transcriptional regulator required for adaptation to changing oxygen levels and virulence

scientific journal article

Mycobacterium tuberculosis pellicles express unique proteins recognized by the host humoral response

scientific article

Mycobacterium tuberculosis universal stress protein Rv2623 regulates bacillary growth by ATP-Binding: requirement for establishing chronic persistent infection

scientific article

Natural infection of guinea pigs exposed to patients with highly drug-resistant tuberculosis ⬇️

scientific article published on April 7, 2011

Non-clinical efficacy and safety of HyVac4:IC31 vaccine administered in a BCG prime-boost regimen

article published in 2010

Non-diabetic hyperglycemia exacerbates disease severity in Mycobacterium tuberculosis infected guinea pigs

scientific article

Norepinephrine stimulates in vitro growth but does not increase pathogenicity of Salmonella choleraesuis in an in vivo model

scientific article published on January 1999

Opposing biological functions of tryptophan catabolizing enzymes during intracellular infection

scientific article published on 11 October 2011

Oral therapy using nanoparticle-encapsulated antituberculosis drugs in guinea pigs infected with Mycobacterium tuberculosis

scientific article

Pathology of Tuberculosis: How the Pathology of Human Tuberculosis Informs and Directs Animal Models

scientific article published on June 2017

Phosphatidylinositol di-mannoside and derivates modulate the immune response to and efficacy of a tuberculosis protein vaccine against Mycobacterium bovis infection.

scientific article

Post-exposure vaccination against Mycobacterium tuberculosis

scientific article

Presence of multiple lesion types with vastly different microenvironments in C3HeB/FeJ mice following aerosol infection with Mycobacterium tuberculosis.

scientific article published on 30 March 2015

Pulmonary lymphatics are primary sites of Mycobacterium tuberculosis infection in guinea pigs infected by aerosol

scientific article

Pulmonary necrosis resulting from DNA vaccination against tuberculosis

scientific article

Reply to Schroecksnadel, et al

scientific article published in 2012

Reversal of Mycobacterium tuberculosis phenotypic drug resistance by 2-aminoimidazole-based small molecules

scientific article

Role for matrix metalloproteinase 9 in granuloma formation during pulmonary Mycobacterium tuberculosis infection

scientific article

Role of chemokine ligand 2 in the protective response to early murine pulmonary tuberculosis

scientific article

Salmonella Shedding in Racing Sled Dogs ⬇️

scientific article published on October 1, 1997

Second generation 2-aminoimidazole based advanced glycation end product inhibitors and breakers

scientific article published on 29 June 2015

Suppression of lymphocyte proliferation by parainfluenza virus type 3-infected bovine alveolar macrophages

scientific article

The Discovery of 2-Aminobenzimidazoles That Sensitize Mycobacterium smegmatis and M. tuberculosis to β-Lactam Antibiotics in a Pattern Distinct from β-Lactamase Inhibitors.

scientific article

The cellular immune response to Mycobacterium tuberculosis infection in the guinea pig.

scientific article published in August 2007

The formation of the granuloma in tuberculosis infection

scientific article

The hypervirulent Mycobacterium tuberculosis strain HN878 induces a potent TH1 response followed by rapid down-regulation

scientific article published on 01 July 2007

The principal sigma factor sigA mediates enhanced growth of Mycobacterium tuberculosis in vivo

scientific journal article

The protective effect of the Mycobacterium bovis BCG vaccine is increased by coadministration with the Mycobacterium tuberculosis 72-kilodalton fusion polyprotein Mtb72F in M. tuberculosis-infected guinea pigs

scientific article

Therapeutic vaccination against relevant high virulence clinical isolates of Mycobacterium tuberculosis

scientific article published on 07 September 2013

Toll-like receptor-induced arginase 1 in macrophages thwarts effective immunity against intracellular pathogens

scientific article

Topical Gel Therapy for Sinonasal Polyposis in Samter's Triad: Preliminary Report ⬇️

scientific article published on 01 November 2012

Topical therapy for refractory rhinosinusitis caused by methicillin-resistant Staphylococcus aureus: First report in a prospective series

scientific article published on 6 February 2018

Toxicosis in cattle from concurrent feeding of monensin and dried distiller's grains contaminated with macrolide antibiotics

scientific article published on 01 January 1999

Tricyclic pyrone analogs: a new class of microtubule-disrupting anticancer drugs effective against murine leukemia cells in vitro ⬇️

scientific article published on February 1, 1998

Truncated gamma-glutamyl carboxylase in rambouillet sheep.

scientific article

Uptake and Accumulation of Oxidized Low-Density Lipoprotein during Mycobacterium tuberculosis Infection in Guinea Pigs ⬇️

scientific article published on March 30, 2012

Use of specific rRNA oligonucleotide probes for microscopic detection of Mycobacterium tuberculosis in culture and tissue specimens

scientific article

Vaccination of guinea pigs using mce operon mutants of Mycobacterium tuberculosis ⬇️

scientific article published on April 22, 2011

Vaccines displaying mycobacterial proteins on biopolyester beads stimulate cellular immunity and induce protection against tuberculosis

scientific article published on 9 November 2011

What is your diagnosis? Cortical lysis, medullary sclerosis, and periosteal bony proliferation of the distal portion of the metacarpus

scientific article published on 01 March 2003

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