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List of works by Suk-Jae Chung

A novel small molecule STAT3 inhibitor SLSI-1216 suppresses proliferation and tumor growth of triple-negative breast cancer cells through apoptotic induction

scientific article published on 22 May 2020

A novel vesicular carrier, transethosome, for enhanced skin delivery of voriconazole: characterization and in vitro/in vivo evaluation

scientific article published on 17 December 2011

A strategy for reducing particulate contamination on opening glass ampoules and development of evaluation methods for its application

scientific article published on 27 June 2011

AAPE proliposomes for topical atopic dermatitis treatment

scientific article published on 04 August 2014

Air-liquid interface (ALI) culture of human bronchial epithelial cell monolayers as an in vitro model for airway drug transport studies

scientific article published on February 2007

Altered metabolism of orally administered loxoprofen in human subjects after an oral administration of loxoprofen for three consecutive days followed by a seven-day washout

scientific article

Altered pharmacokinetics of daunorubicin in rats with CCl4-induced hepatic injury

scientific article published in September 2007

Analysis of structure-activity relationships for the 'B-region' of N-(3-acyloxy-2-benzylpropyl)-N(')-[4-(methylsulfonylamino)benzyl]thiourea analogues as vanilloid receptor antagonists: discovery of an N-hydroxythiourea analogue with potent analgesi

scientific article published in May 2004

Antitumor effect of paclitaxel-loaded PEGylated immunoliposomes against human breast cancer cells

scientific article published on 9 September 2007

Application of a sample pooling method for the accelerated assessment of the rate of uptake of drugs by the brain in rats

scientific article

Bile acid-conjugated chondroitin sulfate A-based nanoparticles for tumor-targeted anticancer drug delivery.

scientific article published on 4 July 2015

Bioanalysis of alpelisib using liquid chromatography–tandem mass spectrometry and application to pharmacokinetic study

scientific article published in 2022

Carfilzomib Delivery by Quinic Acid-Conjugated Nanoparticles: Discrepancy Between Tumoral Drug Accumulation and Anticancer Efficacy in a Murine 4T1 Orthotopic Breast Cancer Model

scientific article published on 13 January 2020

Challenges for Kinetic Identification of Variability Associated with Genetic Polymorphisms of Transporters ⬇️

scientific article published on January 1, 2010

Characterization and in vitro evaluation of freeze-dried microparticles composed of granisetron-cyclodextrin complex and carboxymethylcellulose for intranasal delivery.

scientific article published on 27 August 2010

Characterization of the transport of uracil across Caco-2 and LLC-PK1 cell monolayers

scientific article published in October 2002

Chitosan microspheres as an alveolar macrophage delivery system of ofloxacin via pulmonary inhalation

scientific article published on 08 November 2012

Chitosan oligosaccharide-arachidic acid-based nanoparticles for anti-cancer drug delivery

scientific article

Clinical pharmacokinetics of oxaliplatin and 5-fluorouracil administered in combination with leucovorin in Korean patients with advanced colorectal cancer.

scientific article published on 4 January 2006

Comparison of pharmacokinetics of loxoprofen and its active metabolites after an intravenous, intramuscular, and oral administration of loxoprofen in rats: evidence for extrahepatic metabolism.

scientific article published in October 2005

Comparison of saline vs. blood replenishment after blood sampling in a rat pharmacokinetic study

scholarly article

Contribution of a significant first-pass effect of dimethyl-4,4'-dimethoxy-5,6,5',6'-dimethylene dioxybiphenyl-2,2'-dicarboxylate in the liver to its poor bioavailability in rats

scientific article published in September 2009

Contribution of ion-pair complexation with bile salts to the transport of organic cations across LLC-PK1 cell monolayers

scientific article published on April 1, 2003

Crystal structures of human NSDHL and development of its novel inhibitor with the potential to suppress EGFR activity

scientific article published on 05 March 2020

Decreased secretory transport of a quarternary ammonium, TBuMA, across LLC-PK1 cells by the anionic kidney extract

scientific article published on 15 May 2008

Determination of Belotecan in the Plasma, Bile, and Urine of Rats by High-Performance Liquid Chromatography with Fluorescence Detection and Its Application to a Pharmacokinetic Study

Determination of mequitazine in human plasma by gas-chromatography/mass spectrometry with ion-trap detector and its pharmacokinetics after oral administration to volunteers

scientific article published in October 2005

Determination of the Number of Tissue Groups of Kinetically Distinct Transit Time in Whole-Body Physiologically Based Pharmacokinetic (PBPK) Models II: Practical Application of Tissue Lumping Theories for Pharmacokinetics of Various Compounds

scientific article published in 2022

Determination of zabofloxacin in rat plasma by liquid chromatography with mass spectrometry and its application to pharmacokinetic study ⬇️

scientific article published on 09 November 2010

Development and Validation of Analytical Method for SH-1242 in the Rat and Mouse Plasma by Liquid Chromatography/Tandem Mass Spectrometry

scientific article published on 25 January 2020

Differential changes in functional activity of organic cation transporters in rats with uranyl nitrate-induced acute renal failure

scientific article published on 01 August 2012

Docetaxel microemulsion for enhanced oral bioavailability: preparation and in vitro and in vivo evaluation

scientific article published on 23 August 2009

Dose dependency in the oral bioavailability of an organic cation model, tributylmethyl ammonium (TBuMA), in rats: association with the saturation of efflux by the P-gp system on the apical membrane of the intestinal epithelium

scientific article published in December 2005

Dual CD44 and folate receptor-targeted nanoparticles for cancer diagnosis and anticancer drug delivery.

scientific article published on 16 June 2016

Effect of a new hepatoprotective agent, YH-439, on the hepatobiliary transport of organic cations (OCs): selective inhibition of sinusoidal OCs uptake without influencing glucose uptake and canalicular OCs excretion

scientific article published in March 2005

Effect of an aqueous extract of dried immature fruit of Poncirus trifoliata (L.) Raf. on intestinal transit in rodents with experimental gastrointestinal motility dysfunctions

scientific article published on 15 September 2005

Effect of excipients on the stability and transport of recombinant human epidermal growth factor (rhEGF) across CACO-2 cell monolayers ⬇️

scientific article published on April 1, 2003

Effect of fatty acids on the transdermal delivery of donepezil: in vitro and in vivo evaluation

scientific article published on 20 October 2011

Effect of ion-pair formation with bile salts on the in vitro cellular transport of berberine

scientific article

Effect of nitric oxide on the sinusoidal uptake of organic cations and anions by isolated hepatocytes

scientific article

Effect of nonylphenol ethoxylates (NPEs) on barrier functions of epithelial cell membranes: opening of tight junctions and competitive inhibition of P-gp-mediated efflux

scientific article published on September 2005

Effect of permeation enhancers on transdermal delivery of fluoxetine: in vitro and in vivo evaluation

scientific article published on 5 September 2013

Effect of probenecid on the biliary excretion of belotecan

scientific article

Effect of treatment period with LC478, a disubstituted adamantayl derivative, on P-glycoprotein inhibition: its application to increase docetaxel absorption in rats

scientific article published on 06 December 2019

Effects of 1α,25-dihydroxyvitamin D3 , the natural vitamin D receptor ligand, on the pharmacokinetics of cefdinir and cefadroxil, organic anion transporter substrates, in rat

scientific article published on 29 September 2014

Effects of Nonalcoholic Fatty Liver Disease on Hepatic CYP2B1 and in Vivo Bupropion Disposition in Rats Fed a High-Fat or Methionine/Choline-Deficient Diet.

scientific article published on 19 June 2016

Enhanced electrostatic interaction between chitosan-modified PLGA nanoparticle and tumor

scientific article

Enhanced intestinal absorption of salmon calcitonin (sCT) from proliposomes containing bile salts

scientific article published in September 2005

Enhanced intracellular accumulation of a non-nucleoside anti-cancer agent via increased uptake of its valine ester prodrug through amino acid transporters

scientific article published on 10 January 2012

Enhanced in vitro cellular uptake of P-gp substrate by poloxamer-modified liposomes (PMLs) in MDR cancer cells

scientific article

Enhanced solubility and stability of PEGylated liposomal paclitaxel: in vitro and in vivo evaluation

scientific article published on 13 February 2007

Enhancing effect of surfactants on fexofenadine.HCl transport across the human nasal epithelial cell monolayer

scientific article published on 01 September 2006

Estimation of the minimum permeability coefficient in rats for perfusion-limited tissue distribution in whole-body physiologically-based pharmacokinetics.

scientific article published on 12 February 2017

Evaluation of protein stability and in vitro permeation of lyophilized polysaccharides-based microparticles for intranasal protein delivery

scientific article published on 15 June 2011

Evidence of carrier-mediated transport in the penetration of donepezil into the rat brain

scientific article

Evidence supporting antioxidant action of adipose-derived stem cells: protection of human dermal fibroblasts from oxidative stress

scientific article published on 17 September 2007

Expression and functional activity of P-glycoprotein in passaged primary human nasal epithelial cell monolayers cultured by the air-liquid interface method for nasal drug transport study.

scientific article

Feasibility of the functional expression of the human organic anion transporting polypeptide 1B1 (OATP1B1) and its genetic variant 521T/C in the mouse liver

scientific article published on 10 September 2016

Functional consequences of genetic variations in the human organic anion transporting polypeptide 1B3 (OATP1B3) in the Korean population

scientific article

Functional impairment of P-glycoprotein by sodium nitroprusside pretreatment in mouse brain capillary endothelial cells

scientific article

Functional impairment of rat taurine transporter by activation of nitrogen oxide through superoxide

scientific article published on 13 December 2011

Functional induction of P-glycoprotein in the blood-brain barrier of streptozotocin-induced diabetic rats: evidence for the involvement of nuclear factor-kappaB, a nitrosative stress-sensitive transcription factor, in the regulation

scientific article published on 30 July 2007

Gender differences in the hepatic elimination and pharmacokinetics of lobeglitazone in rats

scientific article published on 21 April 2015

Hepatobiliary excretion of tributylmethylamonium in rats with lipopolysaccharide-induced acute inflammation

scientific article

High body clearance and low oral bioavailability of alantolactone, isolated from Inula helenium, in rats: extensive hepatic metabolism and low stability in gastrointestinal fluids

scientific article published on 10 February 2016

Hyaluronic acid derivative-based self-assembled nanoparticles for the treatment of melanoma

scientific article

Identification of genes enhanced by protein-calorie malnutrition by differential display polymerase chain reaction (expression of fibrinogen B beta chain, B cell translocation gene 1 and thyroid hormone responsive protein genes)

scientific journal article

Identification of metabolites of MDR-1339, an inhibitor of β-amyloid protein aggregation, and kinetic characterization of the major metabolites in rats.

scientific article published on 3 January 2018

Identification of the primary determining factor(s) governing the oral absorption of edaravone in rats

scientific article published on 26 July 2018

In vitro and in vivo evaluation of N,N,N-trimethylphytosphingosine-iodide (TMP) in liposomes for the treatment of angiogenesis and metastasis.

scientific article published on 27 May 2012

In vitro and in vivo evaluation of a novel nonscrotal matrix-type transdermal delivery system of testosterone

scientific article published in March 2005

In vitro and in vivo evaluation of the effect of puerarin on hepatic cytochrome p450-mediated drug metabolism

scientific article published on 07 April 2014

In vitro and in vivo metabolism of pyronaridine characterized by low-energy collision-induced dissociation mass spectrometry with electrospray ionization

scientific article published in September 2004

Inhibition of Organic Anion Transporting Polypeptide 1B1 and 1B3 by Betulinic Acid: Effects of Pre-incubation and Albumin in the Media

scientific article published on 17 February 2018

Involvement of P-glycoprotein, multidrug resistance protein 2 and breast cancer resistance protein in the transport of belotecan and topotecan in Caco-2 and MDCKII cells

scientific article published on 25 July 2008

Iodinated hyaluronic acid oligomer-based nanoassemblies for tumor-targeted drug delivery and cancer imaging.

scientific article published on 29 January 2016

Kinetic analysis about the bidirectional transport of 1-anilino-8-naphthalene sulfonate (ANS) by isolated rat hepatocytes ⬇️

scientific article published on April 1, 2003

Kinetics of the Absorption, Distribution, Metabolism, and Excretion of Lobeglitazone, a Novel Activator of Peroxisome Proliferator-Activated Receptor Gamma in Rats

scientific article

Lack of a primary physicochemical determinant in the direct transport of drugs to the brain after nasal administration in rats: potential involvement of transporters in the pathway

scientific article published on 30 September 2010

Limited role of P-glycoprotein in the intestinal absorption of cyclosporin A.

scientific article published in April 2005

Liposome formulation of paclitaxel with enhanced solubility and stability

scientific article

Liver cancer targeting of Doxorubicin with reduced distribution to the heart using hematoporphyrin-modified albumin nanoparticles in rats

scientific article published on 05 October 2011

Lung-specific delivery of paclitaxel by chitosan-modified PLGA nanoparticles via transient formation of microaggregates

scientific article

Mechanism for increased bioavailability of tacrine in fasted rats

scientific article published in May 2006

Mechanism of the reduced elimination clearance of benzylpenicillin from cerebrospinal fluid in rats with intracisternal administration of lipopolysaccharide

scientific article published in November 2002

Mechanism of the stationary canalicular excretion of tributylmethyl ammonium in rats with a CCl4-induced acute hepatic injury

scientific article published in February 2005

Metabolic interactions of magnolol with cytochrome P450 enzymes: uncompetitive inhibition of CYP1A and competitive inhibition of CYP2C

scientific article published on 02 July 2015

Multiple alterations of canalicular membrane transport activities in rats with CCl(4)-induced hepatic injury

scientific article published in April 2003

Non-vanillyl resiniferatoxin analogues as potent and metabolically stable transient receptor potential vanilloid 1 agonists

scientific article

Novel Hypoxia-Inducible Factor 1α (HIF-1α) Inhibitors for Angiogenesis-Related Ocular Diseases: Discovery of a Novel Scaffold via Ring-Truncation Strategy

scientific article published on 09 October 2018

Novel porous matrix of hyaluronic acid for the three-dimensional culture of chondrocytes

scientific article published on 20 November 2008

Oral bioavailability of new drug leads is a challenge for pharmaceutical scientists

scientific article

P-glycoprotein-mediated transport of berberine across Caco-2 cell monolayers

scientific article published in December 2002

Paracellular permeation-enhancing effect of AT1002 C-terminal amidation in nasal delivery

scientific article

Pharmacokinetic characterization of dehydroevodiamine in the rat brain

scientific article published on February 2004

Pharmacokinetic interaction between oltipraz and dimethyl-4,4‘-dimethoxy-5,6,5′,6’-dimethylene dioxybiphenyl-2,2′-dicarboxylate (DDB) after single intravenous and oral administration to rats ⬇️

scientific article published on September 1, 2003

Pharmacokinetics and first-pass elimination of metoprolol in rats: contribution of intestinal first-pass extraction to low bioavailability of metoprolol

scientific article published on 3 December 2010

Pharmacokinetics and pharmacodynamics of ketoprofen plasters

scientific article published in January 2008

Phenolic modification as an approach to improve the pharmacology of the 3-acyloxy-2-benzylpropyl homovanillic amides and thioureas, a promising class of vanilloid receptor agonists and analgesics

scientific article published on April 2002

Physiologically based pharmacokinetic modeling of SNU-0039, an anti-Alzheimer's agent, in rats

scientific article published on 25 August 2011

Physiologically-Based Pharmacokinetic Modeling for Drug-Drug Interactions of Procainamide and -Acetylprocainamide with Cimetidine, an Inhibitor of rOCT2 and rMATE1, in Rats

scientific article published on 06 March 2019

Poloxamer/cyclodextrin/chitosan-based thermoreversible gel for intranasal delivery of fexofenadine hydrochloride.

scientific article

Poly-L-arginine and dextran sulfate-based nanocomplex for epidermal growth factor receptor (EGFR) siRNA delivery: its application for head and neck cancer treatment

scientific article

Polyethylene glycol-conjugated chondroitin sulfate A derivative nanoparticles for tumor-targeted delivery of anticancer drugs

scientific article published on 18 May 2016

Porous hyaluronic acid/sodium alginate composite scaffolds for human adipose-derived stem cells delivery.

scientific article published on 29 June 2013

Preparation and evaluation of fexofenadine microemulsion for intranasal delivery

Preparation and evaluation of fexofenadine microemulsions for intranasal delivery

scientific article published on August 2010

Preparation and evaluation of paclitaxel-loaded PEGylated immunoliposome

scientific article

Preparation and evaluation of proliposomes containing salmon calcitonin

scientific article published in November 2002

Preparation and evaluation of spray-dried hyaluronic acid microspheres for intranasal delivery of fexofenadine hydrochloride

scientific article

Preparation, characterization and in vitro intestinal absorption of a dry emulsion formulation containing atorvastatin calcium.

scientific article published in January 2009

Prokinetic activity of an aqueous extract from dried immature fruit of Poncirus trifoliata (L.) Raf.

scientific article published on 26 September 2005

Proliferation and chondrogenic differentiation of human adipose-derived mesenchymal stem cells in porous hyaluronic acid scaffold

scientific article published on 30 July 2011

Pyrazole-5-carboxamides, novel inhibitors of receptor for advanced glycation end products (RAGE)

scientific article (publication date: 22 May 2014)

Quantification of CKD-501, lobeglitazone, in rat plasma using a liquid-chromatography/tandem mass spectrometry method and its applications to pharmacokinetic studies

scientific article

Quantification of EC-18, a synthetic monoacetyldiglyceride (1-palmitoyl-2-linoleoyl-3-acetyl-rac-glycerol), in rat and mouse plasma by liquid-chromatography/tandem mass spectrometry

scientific article published on 17 January 2017

Quantification of IDP-73152, a novel antibiotic, in plasma from mice, rats and humans using an ultra-high performance liquid chromatography/tandem mass spectrometry method for use in pharmacokinetic studies

scientific article published on 6 July 2017

Quantification of clotiazepam in human plasma by gas chromatography-mass spectrometry.

scientific article published on 6 March 2006

Quercetin Is a Flavonoid Breast Cancer Resistance Protein Inhibitor with an Impact on the Oral Pharmacokinetics of Sulfasalazine in Rats

scientific article published on 26 April 2020

Rapid and sensitive determination of udenafil in plasma by LC-MS/MS for intranasal pharmacokinetic study in rats

scientific article published on 01 January 2011

Reduced antidiabetic effect of metformin and down-regulation of hepatic Oct1 in rats with ethynylestradiol-induced cholestasis

scientific article

Role of the efflux transporters Abcb1 and Abcg2 in the brain distribution of olaparib in mice

scientific article published in 2022

Saturable distribution of tacrine into the striatal extracellular fluid of the rat: evidence of involvement of multiple organic cation transporters in the transport

scientific article

Saturable sinusoidal uptake is rate-determining process in hepatic elimination of docetaxel in rats

scientific article published on 02 July 2012

Simple liquid chromatography-electrospray ionization mass spectrometry method for the routine determination of salmon calcitonin in serum

scientific article

Simultaneous Determination of Artesunate and Dihydroartemisinin Concentrations in Human Plasma by High Performance Liquid Chromatography-Mass Spectrometry with Electro-Spray Ionization

article by Kyeong-Ryoon Lee et al published 12 January 2010 in Analytical Letters

Simultaneous quantification of volitinib and gefitinib in rat plasma by HPLC-MS/MS for application to a pharmacokinetic study in rats.

scientific article published on 27 July 2017

Skin permeation enhancement of diclofenac by fatty acids

scientific article published in August 2008

Small intestinal transit does not adequately represent postoperative paralytic ileus in rats

scientific article published on 01 December 2002

Smooth muscle relaxation activity of an aqueous extract of dried immature fruit of Poncirus trifoliata (PF-W) on an isolated strip of rat ileum.

scientific article published in August 2013

Specific Inhibition of the Distribution of Lobeglitazone to the Liver by Atorvastatin in Rats: Evidence for a Rat Organic Anion Transporting Polypeptide 1B2-Mediated Interaction in Hepatic Transport

scientific article

Suppression of canine ABCB1 in MDCKII cells unmasks human ABCG2-mediated efflux of olaparib

scientific article published on 05 November 2018

Synergic enhancing-effect of DEET and dodecylamine on the skin permeation of testosterone from a matrix-type transdermal delivery system.

scientific article

Testosterone-independent down-regulation of Oct2 in the kidney medulla from a uranyl nitrate-induced rat model of acute renal failure: effects on distribution of a model organic cation, tetraethylammonium

scientific article published in February 2009

The conditional stimulation of rat organic cation transporter 2, but not its human ortholog, by mesoridazine: the possibility of the involvement of the high-affinity binding site of the transporter in the stimulation.

scientific article

The effects of mixed MPEG-PLA/Pluronic copolymer micelles on the bioavailability and multidrug resistance of docetaxel

scientific article

The identification of lobeglitazone metabolites in rat liver microsomes and the kinetics of the in vivo formation of the major metabolite M1 in rats

scientific article published on 30 July 2015

The limited intestinal absorption via paracellular pathway is responsible for the low oral bioavailability of doxorubicin

scientific article published on 19 December 2012

The suppressed expression and functional activity of hepatic P-glycoprotein in rats with protein-calorie malnutrition

scientific article

Therapeutic Efficacy of ABN401, a Highly Potent and Selective MET Inhibitor, Based on Diagnostic Biomarker Test in MET-Addicted Cancer

scientific article published on 15 June 2020

Transfection of primary human nasal epithelial cells using a biodegradable poly (ester amine) based on polycaprolactone and polyethylenimine as a gene carrier

scientific article

Transport of anti-allergic drugs across the passage cultured human nasal epithelial cell monolayer

scientific article published in October 2005

Transport of gemifloxacin, a 4th generation quinolone antibiotic, in the Caco-2 and engineered MDCKII cells, and potential involvement of efflux transporters in the intestinal absorption of the drug

scientific article

Z-ligustilide and n-Butylidenephthalide Isolated from the Aerial Parts of Angelica tenuissima Inhibit Lipid Accumulation In Vitro and In Vivo

scientific article published on 28 May 2019

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