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List of works by Kah-Whye Peng

Ablation of nectin4 binding compromises CD46 usage by a hybrid vesicular stomatitis virus/measles virus

scientific article published on 11 December 2013

Adenoviral vectors expressing fusogenic membrane glycoproteins activated via matrix metalloproteinase cleavable linkers have significant antitumor potential in the gene therapy of gliomas

scientific article

Affinity thresholds for membrane fusion triggering by viral glycoproteins

scientific article

Amalgamating oncolytic viruses to enhance their safety, consolidate their killing mechanisms, and accelerate their spread

scientific article published on 11 July 2013

Antibody-targeted cell fusion

scientific article published on 15 February 2004

B-Type Natriuretic Peptide Deletion Leads to Progressive Hypertension, Associated Organ Damage, and Reduced Survival: Novel Model for Human Hypertension.

scientific article published on 11 May 2015

Biodistribution of Oncolytic Measles Virus After Intraperitoneal Administration into Ifnar™-CD46Ge Transgenic Mice ⬇️

scientific article published on November 1, 2003

Characteristics of oncolytic vesicular stomatitis virus displaying tumor-targeting ligands

scientific article published on 02 October 2013

Clinical Trials with Oncolytic Measles Virus: Current Status and Future Prospects

scientific article published on 22 February 2017

Comparative oncology evaluation of intravenous recombinant oncolytic Vesicular Stomatitis Virus therapy in spontaneous canine cancer

scientific article published on 20 November 2017

Concordant activity of transgene expression cassettes inserted into E1, E3 and E4 cloning sites in the adenovirus genome

scientific article

Controlled size and morphology of EDTMP-doped hydroxyapatite nanoparticles as model for 153Samarium-EDTMP doping

scientific article

Correction for Tesfay et al., Vesiculovirus Neutralization by Natural IgM and Complement.

scientific article published on 12 January 2015

Curative ex vivo liver-directed gene therapy in a pig model of hereditary tyrosinemia type 1.

scientific article

DARPin-targeting of measles virus: unique bispecificity, effective oncolysis, and enhanced safety

scientific article published on 5 February 2013

Designing and building oncolytic viruses

scientific article published on 31 March 2017

Dual therapy of ovarian cancer using measles viruses expressing carcinoembryonic antigen and sodium iodide symporter

scientific article published on March 2006

Early Events in Retrovirus XMRV Infection of the Wild-Derived MouseMus pahari ⬇️

scientific article published on November 17, 2010

Efficient and stable transduction of resting B lymphocytes and primary chronic lymphocyte leukemia cells using measles virus gp displaying lentiviral vectors.

scientific article

Engineered measles virus as a novel oncolytic viral therapy system for hepatocellular carcinoma

scientific article published in December 2006

Engineering oncolytic measles virus to circumvent the intracellular innate immune response

scientific article published on 16 January 2007

Enhancing cytokine-induced killer cell therapy of multiple myeloma

scientific article published on 8 February 2013

Enhancing the Oncolytic Activity of CD133-Targeted Measles Virus: Receptor Extension or Chimerism with Vesicular Stomatitis Virus Are Most Effective

scientific article published on 26 June 2017

Epidermal growth factor receptor (EGFR)-retargeted measles virus strains effectively target EGFR- or EGFRvIII expressing gliomas

scientific article published on 13 February 2007

Expression of immunomodulatory neutrophil-activating protein of Helicobacter pylori enhances the antitumor activity of oncolytic measles virus

scientific article

Faster replication and higher expression levels of viral glycoproteins give the vesicular stomatitis virus/measles virus hybrid VSV-FH a growth advantage over measles virus

scientific article published on 14 May 2014

High CD46 receptor density determines preferential killing of tumor cells by oncolytic measles virus

scientific article published on July 2004

Image-guided radiovirotherapy for multiple myeloma using a recombinant measles virus expressing the thyroidal sodium iodide symporter ⬇️

scientific article published on November 6, 2003

Immunovirotherapy with vesicular stomatitis virus and PD-L1 blockade enhances therapeutic outcome in murine acute myeloid leukemia

scientific article published on 28 December 2015

In vitro and in vivo properties of adenovirus vectors with increased affinity to CD46

scientific article

Induction of antiviral genes by the tumor microenvironment confers resistance to virotherapy

scientific article published on January 2013

Interaction of measles virus vectors with Auger electron emitting radioisotopes

scientific article published on November 2005

Intraperitoneal therapy of ovarian cancer using an engineered measles virus.

scientific article published in August 2002

Intravascularly administered RGD-displaying measles viruses bind to and infect neovessel endothelial cells in vivo

scientific article

Long-Term Infection and Vertical Transmission of a Gammaretrovirus in a Foreign Host Species ⬇️

scientific article published on January 3, 2012

Mathematical model for radial expansion and conflation of intratumoral infectious centers predicts curative oncolytic virotherapy parameters

scientific article

Mesenchymal stem cell carriers protect oncolytic measles viruses from antibody neutralization in an orthotopic ovarian cancer therapy model

scientific article

Mutations in the stalk region of the measles virus hemagglutinin inhibit syncytium formation but not virus entry

scientific article

Neuroattenuation of vesicular stomatitis virus through picornaviral internal ribosome entry sites

scientific article published on 2 January 2013

New transgenic NIS reporter rats for longitudinal tracking of fibrogenesis by high-resolution imaging

scientific article published in Scientific Reports

Non-invasive in vivo monitoring of trackable viruses expressing soluble marker peptides

scientific article published on 01 May 2002

Noninvasive 3-dimensional imaging of liver regeneration in a mouse model of hereditary tyrosinemia type 1 using the sodium iodide symporter gene

scientific article published on 12 March 2015

Oncolytic Recombinant Vesicular Stomatitis Virus (VSV) Is Nonpathogenic and Nontransmissible in Pigs, a Natural Host of VSV.

scientific article published on 17 May 2017

Oncolytic Virotherapy: A Contest between Apples and Oranges

scientific article published on 6 April 2017

Oncolytic activities of approved mumps and measles vaccines for therapy of ovarian cancer

scientific article published on 01 July 2005

Oncolytic measles and vesicular stomatitis virotherapy for endometrial cancer

scientific article

Oncolytic measles virus as a novel therapy for malignant peripheral nerve sheath tumors

scientific article

Oncolytic measles virus encoding thyroidal sodium iodide symporter for squamous cell cancer of the head and neck radiovirotherapy

scientific article published on 11 January 2012

Oncolytic measles virus expressing the sodium iodide symporter to treat drug-resistant ovarian cancer

scientific article

Oncolytic measles virus strains in the treatment of gliomas

scientific article published on 01 February 2008

Oncolytic measles virus targets high CD46 expression on multiple myeloma cells

scientific article published in June 2006

Oncolytic measles viruses displaying a single-chain antibody against CD38, a myeloma cell marker

scientific article published on 14 November 2002

Oncolytic potency of HER-2 retargeted VSV-FH hybrid viruses: the role of receptor ligand affinity

scientific article published on 5 August 2015

Oncolytic vaccinia virotherapy for endometrial cancer

scientific article published on 14 January 2014

Oncolytic virotherapy

scientific article published on 10 July 2012

Optimizing patient derived mesenchymal stem cells as virus carriers for a phase I clinical trial in ovarian cancer

scientific article published on 24 January 2013

PEGylation of vesicular stomatitis virus extends virus persistence in blood circulation of passively immunized mice

scientific article published on 16 January 2013

Perfusion Pressure Is a Critical Determinant of the Intratumoral Extravasation of Oncolytic Viruses

scientific article published on 9 December 2015

Phase I trial of intraperitoneal administration of an oncolytic measles virus strain engineered to express carcinoembryonic antigen for recurrent ovarian cancer

scientific article

Preclinical Development of Oncolytic Immunovirotherapy for Treatment of HPVPOS Cancers.

scientific article published on 5 July 2018

Preclinical safety and activity of recombinant VSV-IFN-β in an immunocompetent model of squamous cell carcinoma of the head and neck

scientific article published on February 2014

Primer on Medical Genomics Part X: Gene Therapy ⬇️

scientific article published on November 1, 2003

Prostate-specific membrane antigen retargeted measles virotherapy for the treatment of prostate cancer

scientific article

Reengineering paramyxovirus tropism

scientific article published on 01 November 2004

Remission of disseminated cancer after systemic oncolytic virotherapy

scientific article

Reporter gene imaging identifies intratumoral infection voids as a critical barrier to systemic oncolytic virus efficacy

scientific article published on 10 December 2014

Rescue and propagation of fully retargeted oncolytic measles viruses

scientific article published on 30 January 2005

Retargeted oncolytic measles strains entering via the EGFRvIII receptor maintain significant antitumor activity against gliomas with increased tumor specificity

scientific article published on December 2006

Retargeting vesicular stomatitis virus using measles virus envelope glycoproteins

scientific article

Robust Oncolytic Virotherapy Induces Tumor Lysis Syndrome and Associated Toxicities in the MPC-11 Plasmacytoma Model

scientific article published on 27 September 2016

Safety Studies in Tumor and Non-Tumor-Bearing Mice in Support of Clinical Trials Using Oncolytic VSV-IFNβ-NIS.

scientific article

Safety Study: Intraventricular Injection of a Modified Oncolytic Measles Virus into Measles-Immune, hCD46-Transgenic, IFNαRko Mice.

scientific article published on 7 September 2016

Safety studies on intrahepatic or intratumoral injection of oncolytic vesicular stomatitis virus expressing interferon-beta in rodents and nonhuman primates

scientific article published in April 2010

Safety studies on intravenous administration of oncolytic recombinant vesicular stomatitis virus in purpose-bred beagle dogs

scientific article

Safety, pharmacokinetics, metabolism and radiation dosimetry of 18F-tetrafluoroborate (18F-TFB) in healthy human subjects

scientific article published on 27 October 2017

Synergistic activity of the proteasome inhibitor PS-341 with non-myeloablative 153-Sm-EDTMP skeletally targeted radiotherapy in an orthotopic model of multiple myeloma

scientific article published on 19 January 2006

Synthesis and evaluation of 18F-hexafluorophosphate as a novel PET probe for imaging of sodium/iodide symporter in a murine C6-glioma tumor model

scientific article

Synthesis of 18F-Tetrafluoroborate via Radiofluorination of Boron Trifluoride and Evaluation in a Murine C6-Glioma Tumor Model

scientific article published on 21 April 2016

Systemic therapy of disseminated myeloma in passively immunized mice using measles virus-infected cell carriers

scientific article

Systemically delivered measles virus-infected mesenchymal stem cells can evade host immunity to inhibit liver cancer growth.

scientific article

The emerging role of oncolytic virus therapy against cancer

scientific article published in April 2018

The use of a tropism-modified measles virus in folate receptor-targeted virotherapy of ovarian cancer

scientific article published in October 2006

The utility of cells as vehicles for oncolytic virus therapies.

scientific article published on August 2008

Tumor-associated macrophages infiltrate plasmacytomas and can serve as cell carriers for oncolytic measles virotherapy of disseminated myeloma

scientific article

Use of a vaccine strain of measles virus genetically engineered to produce carcinoembryonic antigen as a novel therapeutic agent against glioblastoma multiforme ⬇️

scientific article published on May 15, 2003

Vesiculovirus neutralization by natural IgM and complement

scientific article published on 19 March 2014

Viruses as anticancer drugs

scientific article published on 18 June 2007

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