List of works - Arthur Kaser

A key role for Pre-B cell colony-enhancing factor in experimental hepatitis

scientific article

A role for oncostatin M in inflammatory bowel disease

scientific article published on May 2017

ATG16L1 Crohn's disease risk stresses the endoplasmic reticulum of Paneth cells

scientific article

ATG16L1 orchestrates interleukin-22 signaling in the intestinal epithelium via cGAS-STING

scientific article published on 25 September 2018

Adaptive immunity in inflammatory bowel disease: state of the art.

scientific article published on July 2008

Adiponectin and JNK: metabolic/inflammatory pathways affecting gastrointestinal carcinogenesis

scientific article published in December 2009

Anti-IL-12/23 in Crohn's disease: bench and bedside

scientific article

Anti-inflammatory effects of excessive weight loss: potent suppression of adipose interleukin 6 and tumour necrosis factor alpha expression

scientific article published on 21 July 2010

Anti-inflammatory effects of hepatocyte growth factor: induction of interleukin-1 receptor antagonist.

scientific article

Anti-tumor necrosis factor-alpha monoclonal antibody therapy in severe alcoholic hepatitis.

scientific article published in April 2003

Antitumour necrosis factor therapy in Crohn's disease

scientific article

Autophagy, Microbial Sensing, Endoplasmic Reticulum Stress, and Epithelial Function in Inflammatory Bowel Disease ⬇️

scientific article published on May 1, 2011

C13orf31 (FAMIN) is a central regulator of immunometabolic function

scientific journal article

CD1d-Restricted pathways in hepatocytes control local natural killer T cell homeostasis and hepatic inflammation

scientific article published on 11 September 2017

CD1d-restricted T cell pathways at the epithelial-lymphocyte-luminal interface

scientific article published on June 2004

Cd1d-dependent regulation of bacterial colonization in the intestine of mice

scientific article published on 06 April 2009

Cell biology: Stressful genetics in Crohn's disease

scientific article published on 19 February 2014

Characterization of animal models for primary sclerosing cholangitis (PSC).

scientific article published on 19 February 2014

Cholangiocytes derived from human induced pluripotent stem cells for disease modeling and drug validation

scientific article published on 13 July 2015

Clinical presentation of venous thromboembolism in inflammatory bowel disease ⬇️

scientific article published on November 3, 2012

Control of CD1d-restricted antigen presentation and inflammation by sphingomyelin

scientific article published on 21 October 2019

Controversy over NOD2, inflammation, and defensins

scientific article published on November 2010

Crohn's disease: NOD2, autophagy and ER stress converge

scientific article

Dead on Arrival: Understanding the Failure of CTLA4-Immunoglobulin Therapy in Inflammatory Bowel Disease ⬇️

scientific article published on May 21, 2012

Deciphering the Genetic Predisposition to Primary Sclerosing Cholangitis ⬇️

scientific article published on 02 May 2011

Defective ATG16L1-mediated removal of IRE1α drives Crohn's disease-like ileitis.

scientific article published on 12 January 2017

Dietary lipids fuel GPX4-restricted enteritis resembling Crohn's disease

scientific article published on 14 April 2020

ER stress transcription factor Xbp1 suppresses intestinal tumorigenesis and directs intestinal stem cells

scientific article published on 16 September 2013

Elevated systemic levels of free interleukin-18 (IL-18) in patients with Crohn's disease

scientific article published on 01 January 2005

Endoplasmic Reticulum Stress and Inflammation ⬇️

scientific article published on July 12, 2012

Endoplasmic reticulum stress and inflammatory bowel disease

scientific article published on June 1, 2011

Endoplasmic reticulum stress in the intestinal epithelium and inflammatory bowel disease

scientific article published on 23 February 2009

Endoplasmic reticulum stress: implications for inflammatory bowel disease pathogenesis

scientific article published on July 2010

Endotoxin and its binding proteins in chronic liver disease: the effect of transjugular intrahepatic portosystemic shunting

scientific article published on 01 October 2002

Epithelial IL-23R Signaling Licenses Protective IL-22 Responses in Intestinal Inflammation

scientific article

Epithelial calcineurin controls microbiota-dependent intestinal tumor development

scientific article published on 4 April 2016

Epithelial endoplasmic reticulum stress orchestrates a protective IgA response

scientific article published on 01 March 2019

Expansion and function of CD8+ T cells expressing Ly49 inhibitory receptors specific for MHC class I molecules

scientific article published in September 2004

FAMIN Is a Multifunctional Purine Enzyme Enabling the Purine Nucleotide Cycle

scientific article published on 01 February 2020

FAMIN Is a Multifunctional Purine Enzyme Enabling the Purine Nucleotide Cycle

scientific article published on 01 January 2020

Failure of interleukin 13 blockade in ulcerative colitis

scientific article published on 24 March 2015

GPR35 promotes glycolysis, proliferation, and oncogenic signaling by engaging with the sodium potassium pump

scientific article published on 01 January 2019

Generation of primary human intestinal T cell transcriptomes reveals differential expression at genetic risk loci for immune-mediated disease

scientific article

Genes and environment: how will our concepts on the pathophysiology of IBD develop in the future?

scientific article

Genome-wide association analysis in primary sclerosing cholangitis

scientific article

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

scientific article

Gut microbiome, obesity, and metabolic dysfunction ⬇️

scientific article published on June 1, 2011

Hepatitis B virus-induced lipid alterations contribute to natural killer T cell-dependent protective immunity

scientific article

How to modulate inflammatory cytokines in liver diseases

scientific article published on November 2006

IDO1+ Paneth cells promote immune escape of colorectal cancer

scientific article published on 22 May 2020

Impaired Autophagy in CD11b+ Dendritic Cells Expands CD4+ Regulatory T Cells and Limits Atherosclerosis in Mice

scientific article published on 15 October 2019

Impaired counter-regulation of interleukin-1 by the soluble IL-1 receptor type II in patients with chronic liver disease

scientific article published on 01 January 2008

Increased expression of CCL20 in human inflammatory bowel disease

scientific article published in January 2004

Inflammatory bowel disease is a risk factor for recurrent venous thromboembolism

scientific article published on 12 June 2010

Inflammatory bowel diseases: highlights from the United European Gastroenterology Week 2008

scientific article published on 01 February 2009

Innate immunity in gastrointestinal disorders: basic and therapeutic concepts.

scientific article published on 11 October 2012

Innate immunity. A Spaetzle-like role for nerve growth factor β in vertebrate immunity to Staphylococcus aureus

scientific article

Interferon-alpha controls IL-17 expression in vitro and in vivo

scientific article published on 30 August 2008

Interferon-alpha suppresses leptin levels: studies in interferon-alpha treated patients with hepatitis C virus infection and murine adipocytes.

scientific article published on April 2002

Interleukin-18 attracts plasmacytoid dendritic cells (DC2s) and promotes Th1 induction by DC2s through IL-18 receptor expression ⬇️

scientific article published on September 22, 2003

Interleukin-22 orchestrates a pathological endoplasmic reticulum stress response transcriptional programme in colonic epithelial cells

scientific article published on 02 December 2019

Intestinal epithelial cell endoplasmic reticulum stress promotes MULT1 up-regulation and NKG2D-mediated inflammation.

scientific article published on 26 July 2017

Lessons from type I interferons in ulcerative colitis

scientific article

Lipocalin 2 Protects from Inflammation and Tumorigenesis Associated with Gut Microbiota Alterations.

scientific article

Mechanisms of iron mediated regulation of the duodenal iron transporters divalent metal transporter 1 and ferroportin 1

scientific journal article

Microsomal triglyceride transfer protein regulates endogenous and exogenous antigen presentation by group 1 CD1 molecules

scientific article published on August 2008

Mode of function of biological anti-TNF agents in the treatment of inflammatory bowel diseases

scientific article published on July 2007

Monoclonal antibody specific for TIRC7 induces donor-specific anergy and prevents rejection of cardiac allografts in mice

scientific article

Natural killer T cells in mucosal homeostasis

scientific article

Neonatal Fc receptor for IgG regulates mucosal immune responses to luminal bacteria

scientific article

Neurokinin-1 receptor interacts with PrP(106-126)-induced dendritic cell migration and maturation

scientific article published on 01 January 2005

New Insights Into the Regulation of Natural-Killer Group 2 Member D (NKG2D) and NKG2D-Ligands: Endoplasmic Reticulum Stress and CEA-Related Cell Adhesion Molecule 1.

scientific article

Novel insights into autoimmune liver diseases provided by genome-wide association studies ⬇️

scientific article published on 07 August 2013

Obesity and the microbiota.

scientific article published on 25 March 2009

Overexpression of indoleamine 2,3-dioxygenase in human inflammatory bowel disease

scientific article published in October 2004

Paneth cell alertness to pathogens maintained by vitamin D receptors

scientific article published on 17 November 2020

Paneth cells and inflammation dance together in Crohn's disease

scientific article published on December 2008

Paneth cells as a site of origin for intestinal inflammation.

scientific article

Paternal chronic colitis causes epigenetic inheritance of susceptibility to colitis.

scientific article published on 19 August 2016

Pathways for the regulation of interferon-gamma-inducible genes by iron in human monocytic cells.

scientific article published in August 2003

Personalized Treatment in Inflammatory Bowel Disease: For Another Time

scientific article published on 08 September 2018

Plasma levels of interleukin-18 and interleukin-18 binding protein are elevated in patients with chronic liver disease

scientific article published on 01 November 2002

Primary deficiency of microsomal triglyceride transfer protein in human abetalipoproteinemia is associated with loss of CD1 function

scientific article

Protective mucosal immunity mediated by epithelial CD1d and IL-10.

scientific article

Recent advances in inflammatory bowel disease: mucosal immune cells in intestinal inflammation

scientific article

Regurgitation of bile acids from leaky bile ducts causes sclerosing cholangitis in Mdr2 (Abcb4) knockout mice

scientific article published in July 2004

Reversal of murine alcoholic steatohepatitis by pepducin-based functional blockade of interleukin-8 receptors

scientific article published on 8 February 2016

Role of IL-10 for induction of anemia during inflammation

scientific article published in August 2002

Role of NKT cells in the digestive system. III. Role of NKT cells in intestinal immunity

scientific article published on 23 August 2007

Role of endoplasmic reticulum stress and autophagy as interlinking pathways in the pathogenesis of inflammatory bowel disease

scientific article

Role of nuclear receptors and hepatocyte-enriched transcription factors for Ntcp repression in biliary obstruction in mouse liver

scientific article published on 7 July 2005

SHP1 phosphatase-dependent T cell inhibition by CEACAM1 adhesion molecule isoforms

scientific journal article

Seventeen in Crohn's disease: less prime than we thought?

scientific article published on 11 June 2012

Sphingosine Kinase-Dependent Migration of Immature Dendritic Cells in Response to Neurotoxic Prion Protein Fragment ⬇️

scientific article published on May 1, 2003

Suppression of interleukin-17 by type I interferons: a contributing factor in virus-induced immunosuppression?

scientific article published on March 2009

Survive an innate immune response through XBP1.

scientific article published on May 2010

The RANKL/OPG system and bone mineral density in patients with chronic liver disease

scientific article published on 5 July 2005

The biliary epithelium presents antigens to and activates natural killer T cells

scientific article

The other way round: colitis regulates regulatory T cells

scientific article published on 01 June 2004

The road to Crohn's disease

scientific article

The unfolded protein response and gastrointestinal disease ⬇️

scientific article published on April 16, 2013

The unfolded protein response and its role in intestinal homeostasis and inflammation.

scientific article

Toll-like receptor 4-mediated endoplasmic reticulum stress in intestinal crypts induces necrotizing enterocolitis.

scientific article published on 11 February 2014

Type I interferon signalling in the intestinal epithelium affects Paneth cells, microbial ecology and epithelial regeneration.

scientific article

Type I interferons and their therapeutic role in Th2-regulated inflammatory disorders

scientific article published on April 2004

Visfatin, an adipocytokine with proinflammatory and immunomodulating properties

scientific article published in February 2007

XBP1 links ER stress to intestinal inflammation and confers genetic risk for human inflammatory bowel disease

scientific article

α4β7 integrin: beyond T cell trafficking.

scientific article published on 11 December 2013

“ER Stress(ed Out)!”: Paneth Cells and Ischemia–Reperfusion Injury of the Small Intestine ⬇️

scientific article published on December 18, 2010

“Metabolic Aspects” In Inflammatory Bowel Diseases ⬇️

scientific article published on July 1, 2012

List of works by Arthur Kaser

A key role for Pre-B cell colony-enhancing factor in experimental hepatitis

A role for oncostatin M in inflammatory bowel disease

ATG16L1 Crohn's disease risk stresses the endoplasmic reticulum of Paneth cells

ATG16L1 orchestrates interleukin-22 signaling in the intestinal epithelium via cGAS-STING

Adaptive immunity in inflammatory bowel disease: state of the art.

Adiponectin and JNK: metabolic/inflammatory pathways affecting gastrointestinal carcinogenesis

Anti-IL-12/23 in Crohn's disease: bench and bedside

Anti-inflammatory effects of excessive weight loss: potent suppression of adipose interleukin 6 and tumour necrosis factor alpha expression

Anti-inflammatory effects of hepatocyte growth factor: induction of interleukin-1 receptor antagonist.

Anti-tumor necrosis factor-alpha monoclonal antibody therapy in severe alcoholic hepatitis.

Antitumour necrosis factor therapy in Crohn's disease

Autophagy, Microbial Sensing, Endoplasmic Reticulum Stress, and Epithelial Function in Inflammatory Bowel Disease ⬇️

C13orf31 (FAMIN) is a central regulator of immunometabolic function

CD1d-Restricted pathways in hepatocytes control local natural killer T cell homeostasis and hepatic inflammation

CD1d-restricted T cell pathways at the epithelial-lymphocyte-luminal interface

Cd1d-dependent regulation of bacterial colonization in the intestine of mice

Cell biology: Stressful genetics in Crohn's disease

Characterization of animal models for primary sclerosing cholangitis (PSC).

Cholangiocytes derived from human induced pluripotent stem cells for disease modeling and drug validation

Clinical presentation of venous thromboembolism in inflammatory bowel disease ⬇️

Control of CD1d-restricted antigen presentation and inflammation by sphingomyelin

Controversy over NOD2, inflammation, and defensins

Crohn's disease: NOD2, autophagy and ER stress converge

Dead on Arrival: Understanding the Failure of CTLA4-Immunoglobulin Therapy in Inflammatory Bowel Disease ⬇️

Deciphering the Genetic Predisposition to Primary Sclerosing Cholangitis ⬇️

Defective ATG16L1-mediated removal of IRE1α drives Crohn's disease-like ileitis.

Dietary lipids fuel GPX4-restricted enteritis resembling Crohn's disease

ER stress transcription factor Xbp1 suppresses intestinal tumorigenesis and directs intestinal stem cells

Elevated systemic levels of free interleukin-18 (IL-18) in patients with Crohn's disease

Endoplasmic Reticulum Stress and Inflammation ⬇️

Endoplasmic reticulum stress and inflammatory bowel disease

Endoplasmic reticulum stress in the intestinal epithelium and inflammatory bowel disease

Endoplasmic reticulum stress: implications for inflammatory bowel disease pathogenesis

Endotoxin and its binding proteins in chronic liver disease: the effect of transjugular intrahepatic portosystemic shunting

Epithelial IL-23R Signaling Licenses Protective IL-22 Responses in Intestinal Inflammation

Epithelial calcineurin controls microbiota-dependent intestinal tumor development

Epithelial endoplasmic reticulum stress orchestrates a protective IgA response

Expansion and function of CD8+ T cells expressing Ly49 inhibitory receptors specific for MHC class I molecules

FAMIN Is a Multifunctional Purine Enzyme Enabling the Purine Nucleotide Cycle

FAMIN Is a Multifunctional Purine Enzyme Enabling the Purine Nucleotide Cycle

Failure of interleukin 13 blockade in ulcerative colitis

GPR35 promotes glycolysis, proliferation, and oncogenic signaling by engaging with the sodium potassium pump

Generation of primary human intestinal T cell transcriptomes reveals differential expression at genetic risk loci for immune-mediated disease

Genes and environment: how will our concepts on the pathophysiology of IBD develop in the future?

Genome-wide association analysis in primary sclerosing cholangitis

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Gut microbiome, obesity, and metabolic dysfunction ⬇️

Hepatitis B virus-induced lipid alterations contribute to natural killer T cell-dependent protective immunity

How to modulate inflammatory cytokines in liver diseases

IDO1+ Paneth cells promote immune escape of colorectal cancer

Impaired Autophagy in CD11b+ Dendritic Cells Expands CD4+ Regulatory T Cells and Limits Atherosclerosis in Mice

Impaired counter-regulation of interleukin-1 by the soluble IL-1 receptor type II in patients with chronic liver disease

Increased expression of CCL20 in human inflammatory bowel disease

Inflammatory bowel disease is a risk factor for recurrent venous thromboembolism

Inflammatory bowel diseases: highlights from the United European Gastroenterology Week 2008

Innate immunity in gastrointestinal disorders: basic and therapeutic concepts.

Innate immunity. A Spaetzle-like role for nerve growth factor β in vertebrate immunity to Staphylococcus aureus

Interferon-alpha controls IL-17 expression in vitro and in vivo

Interferon-alpha suppresses leptin levels: studies in interferon-alpha treated patients with hepatitis C virus infection and murine adipocytes.

Interleukin-18 attracts plasmacytoid dendritic cells (DC2s) and promotes Th1 induction by DC2s through IL-18 receptor expression ⬇️

Interleukin-22 orchestrates a pathological endoplasmic reticulum stress response transcriptional programme in colonic epithelial cells

Intestinal epithelial cell endoplasmic reticulum stress promotes MULT1 up-regulation and NKG2D-mediated inflammation.

Lessons from type I interferons in ulcerative colitis

Lipocalin 2 Protects from Inflammation and Tumorigenesis Associated with Gut Microbiota Alterations.

Mechanisms of iron mediated regulation of the duodenal iron transporters divalent metal transporter 1 and ferroportin 1

Microsomal triglyceride transfer protein regulates endogenous and exogenous antigen presentation by group 1 CD1 molecules

Mode of function of biological anti-TNF agents in the treatment of inflammatory bowel diseases

Monoclonal antibody specific for TIRC7 induces donor-specific anergy and prevents rejection of cardiac allografts in mice

Natural killer T cells in mucosal homeostasis

Neonatal Fc receptor for IgG regulates mucosal immune responses to luminal bacteria

Neurokinin-1 receptor interacts with PrP(106-126)-induced dendritic cell migration and maturation

New Insights Into the Regulation of Natural-Killer Group 2 Member D (NKG2D) and NKG2D-Ligands: Endoplasmic Reticulum Stress and CEA-Related Cell Adhesion Molecule 1.

Novel insights into autoimmune liver diseases provided by genome-wide association studies ⬇️

Obesity and the microbiota.

Overexpression of indoleamine 2,3-dioxygenase in human inflammatory bowel disease

Paneth cell alertness to pathogens maintained by vitamin D receptors

Paneth cells and inflammation dance together in Crohn's disease

Paneth cells as a site of origin for intestinal inflammation.

Paternal chronic colitis causes epigenetic inheritance of susceptibility to colitis.