List of works - Facundo D Batista

A generalized HIV vaccine design strategy for priming of broadly neutralizing antibody responses

scientific article published on 31 October 2019

A switch from canonical to noncanonical autophagy shapes B cell responses.

scientific article published on February 2017

A talin-dependent LFA-1 focal zone is formed by rapidly migrating T lymphocytes.

scientific article

Antibody production relies on the tRNA inosine wobble modification to meet biased codon demand

scientific article published on 11 January 2024

B cell receptor-mediated uptake of CD1d-restricted antigen augments antibody responses by recruiting invariant NKT cell help in vivo

scholarly article

B cell recognition of membrane-bound antigen: an exquisite way of sensing ligands

scientific article

B-cell activation by membrane-bound antigens is facilitated by the interaction of VLA-4 with VCAM-1

scientific article

CD169(+) macrophages present lipid antigens to mediate early activation of iNKT cells in lymph nodes

scientific article

CD19 is essential for B cell activation by promoting B cell receptor–antigen microcluster formation in response to membrane-bound ligand

scientific article published on 02 December 2007

Cdc42 is a key regulator of B cell differentiation and is required for antiviral humoral immunity.

scientific article

Correction: Novel in vitro booster vaccination to rapidly generate antigen-specific human monoclonal antibodies

scientific article published on 21 August 2017

Daughter B cells are not created equal: Asymmetric segregation of antigen during B cell division ⬇️

scientific article published on June 15, 2012

Dock8 mutations cripple B cell immunological synapses, germinal centers and long-lived antibody production.

scientific article

Dynamic cortical actin remodeling by ERM proteins controls BCR microcluster organization and integrity ⬇️

scientific article published on April 11, 2011

Dynamic reorganisation of intermediate filaments coordinates early B-cell activation

scientific article published on 20 August 2018

Dynamics of the actin cytoskeleton mediates receptor cross talk: An emerging concept in tuning receptor signaling

scientific article

Early events in B cell activation

scientific article

Early events of B cell activation by antigen

scientific article published on 24 March 2009

Generation and iterative affinity maturation of antibodies in vitro using hypermutating B-cell lines

scientific article published on 15 October 2002

Host response. Inflammation-induced disruption of SCS macrophages impairs B cell responses to secondary infection.

scientific article published on February 2015

Induction of metabolic quiescence defines the transitional to follicular B cell switch

scientific article published on 22 October 2019

Interaction of CD22 with alpha2,6-linked sialoglycoconjugates: innate recognition of self to dampen B cell autoreactivity?

scientific article published on February 2002

Mechanistic insight into lymphocyte activation through quantitative imaging and theoretical modelling

scientific article published on 30 July 2007

Microsignalosomes: spatially resolved receptor signalling

scientific article published on October 2009

Multiplexed CRISPR/CAS9-mediated engineering of pre-clinical mouse models bearing native human B cell receptors

scientific article published on 01 December 2020

Nanoscale organization and dynamics of the siglec CD22 cooperate with the cytoskeleton in restraining BCR signalling.

scientific article published on 15 December 2015

Nck-mediated recruitment of BCAP to the BCR regulates the PI(3)K-Akt pathway in B cells

scientific article

Neutrophils--the unexpected helpers of B-cell activation

scientific article published on February 2012

New insights into the early molecular events underlying B cell activation

scientific article published on May 2008

Novel in vitro booster vaccination to rapidly generate antigen-specific human monoclonal antibodies

scientific article

One-step CRISPR/Cas9 method for the rapid generation of human antibody heavy chain knock-in mice

scientific article published on 07 August 2018

Organisation and dynamics of antigen receptors: implications for lymphocyte signalling

scientific article published on 29 April 2010

Phospholipase C-gamma2 and Vav cooperate within signaling microclusters to propagate B cell spreading in response to membrane-bound antigen

scientific article published on 24 March 2008

RIF1 is essential for 53BP1-dependent nonhomologous end joining and suppression of DNA double-strand break resection.

scientific article

Regulation of integrin activation through the B-cell receptor

scientific article published in July 2008

Retrospective. Michael Neuberger (1953-2013).

scientific article

Synthetic iNKT cell-agonists as vaccine adjuvants--finding the balance

scientific article published on 12 May 2010

The Actin and Tetraspanin Networks Organize Receptor Nanoclusters to Regulate B Cell Receptor-Mediated Signaling

article

The B-cell antigen receptor signals through a preformed transducer module of SLP65 and CIN85 ⬇️

scientific article published on August 5, 2011

The Cytoskeleton Coordinates the Early Events of B-cell Activation ⬇️

scientific article published on February 1, 2011

The Dok-3/Grb2 adaptor module promotes inducible association of the lipid phosphatase SHIP with the BCR in a coreceptor-independent manner

scientific article published on 23 August 2016

The Dok-3/Grb2 protein signal module attenuates Lyn kinase-dependent activation of Syk kinase in B cell antigen receptor microclusters

scientific article published on 5 December 2012

The Small Rho GTPase TC10 Modulates B Cell Immune Responses.

scientific article

The adaptor protein CIN85 assembles intracellular signaling clusters for B cell activation

scientific article

The length of lipids bound to human CD1d molecules modulates the affinity of NKT cell TCR and the threshold of NKT cell activation

scientific article published on 7 May 2007

The location of splenic NKT cells favours their rapid activation by blood-borne antigen

scientific article

The membrane skeleton controls diffusion dynamics and signaling through the B cell receptor

scientific article

The rap GTPases regulate B cell morphology, immune-synapse formation, and signaling by particulate B cell receptor ligands.

scientific article

The role of integrins and coreceptors in refining thresholds for B-cell responses

scientific article published on August 2007

The who, how and where of antigen presentation to B cells

scientific article

Tuning of in vivo cognate B-T cell interactions by Intersectin 2 is required for effective anti-viral B cell immunity.

scientific article published on 16 January 2018

Visualizing a role for the actin cytoskeleton in the regulation of B-cell activation

scientific article published on September 2010

Visualizing the molecular and cellular events underlying the initiation of B-cell activation

scientific article published on January 2009

Wiskott-Aldrich Syndrome Interacting Protein Deficiency Uncovers the Role of the Co-receptor CD19 as a Generic Hub for PI3 Kinase Signaling in B Cells.

scientific article published on 5 October 2015

Wiskott-Aldrich syndrome protein deficiency in B cells results in impaired peripheral homeostasis

scientific article published on 07 August 2008

List of works by Facundo D Batista

A generalized HIV vaccine design strategy for priming of broadly neutralizing antibody responses

A switch from canonical to noncanonical autophagy shapes B cell responses.

A talin-dependent LFA-1 focal zone is formed by rapidly migrating T lymphocytes.

Antibody production relies on the tRNA inosine wobble modification to meet biased codon demand

B cell receptor-mediated uptake of CD1d-restricted antigen augments antibody responses by recruiting invariant NKT cell help in vivo

B cell recognition of membrane-bound antigen: an exquisite way of sensing ligands

B-cell activation by membrane-bound antigens is facilitated by the interaction of VLA-4 with VCAM-1

CD169(+) macrophages present lipid antigens to mediate early activation of iNKT cells in lymph nodes

CD19 is essential for B cell activation by promoting B cell receptor–antigen microcluster formation in response to membrane-bound ligand

Cdc42 is a key regulator of B cell differentiation and is required for antiviral humoral immunity.

Correction: Novel in vitro booster vaccination to rapidly generate antigen-specific human monoclonal antibodies

Daughter B cells are not created equal: Asymmetric segregation of antigen during B cell division ⬇️

Dock8 mutations cripple B cell immunological synapses, germinal centers and long-lived antibody production.

Dynamic cortical actin remodeling by ERM proteins controls BCR microcluster organization and integrity ⬇️

Dynamic reorganisation of intermediate filaments coordinates early B-cell activation

Dynamics of the actin cytoskeleton mediates receptor cross talk: An emerging concept in tuning receptor signaling

Early events in B cell activation

Early events of B cell activation by antigen

Generation and iterative affinity maturation of antibodies in vitro using hypermutating B-cell lines

Host response. Inflammation-induced disruption of SCS macrophages impairs B cell responses to secondary infection.

Induction of metabolic quiescence defines the transitional to follicular B cell switch

Interaction of CD22 with alpha2,6-linked sialoglycoconjugates: innate recognition of self to dampen B cell autoreactivity?

Mechanistic insight into lymphocyte activation through quantitative imaging and theoretical modelling

Microsignalosomes: spatially resolved receptor signalling

Multiplexed CRISPR/CAS9-mediated engineering of pre-clinical mouse models bearing native human B cell receptors

Nanoscale organization and dynamics of the siglec CD22 cooperate with the cytoskeleton in restraining BCR signalling.

Nck-mediated recruitment of BCAP to the BCR regulates the PI(3)K-Akt pathway in B cells

Neutrophils--the unexpected helpers of B-cell activation

New insights into the early molecular events underlying B cell activation

Novel in vitro booster vaccination to rapidly generate antigen-specific human monoclonal antibodies

One-step CRISPR/Cas9 method for the rapid generation of human antibody heavy chain knock-in mice

Organisation and dynamics of antigen receptors: implications for lymphocyte signalling

Phospholipase C-gamma2 and Vav cooperate within signaling microclusters to propagate B cell spreading in response to membrane-bound antigen

RIF1 is essential for 53BP1-dependent nonhomologous end joining and suppression of DNA double-strand break resection.

Regulation of integrin activation through the B-cell receptor

Retrospective. Michael Neuberger (1953-2013).

Synthetic iNKT cell-agonists as vaccine adjuvants--finding the balance

The Actin and Tetraspanin Networks Organize Receptor Nanoclusters to Regulate B Cell Receptor-Mediated Signaling

The B-cell antigen receptor signals through a preformed transducer module of SLP65 and CIN85 ⬇️

The Cytoskeleton Coordinates the Early Events of B-cell Activation ⬇️

The Dok-3/Grb2 adaptor module promotes inducible association of the lipid phosphatase SHIP with the BCR in a coreceptor-independent manner

The Dok-3/Grb2 protein signal module attenuates Lyn kinase-dependent activation of Syk kinase in B cell antigen receptor microclusters

The Small Rho GTPase TC10 Modulates B Cell Immune Responses.

The adaptor protein CIN85 assembles intracellular signaling clusters for B cell activation

The length of lipids bound to human CD1d molecules modulates the affinity of NKT cell TCR and the threshold of NKT cell activation

The location of splenic NKT cells favours their rapid activation by blood-borne antigen

The membrane skeleton controls diffusion dynamics and signaling through the B cell receptor

The rap GTPases regulate B cell morphology, immune-synapse formation, and signaling by particulate B cell receptor ligands.

The role of integrins and coreceptors in refining thresholds for B-cell responses

The who, how and where of antigen presentation to B cells

Tuning of in vivo cognate B-T cell interactions by Intersectin 2 is required for effective anti-viral B cell immunity.

Visualizing a role for the actin cytoskeleton in the regulation of B-cell activation

Visualizing the molecular and cellular events underlying the initiation of B-cell activation

Wiskott-Aldrich Syndrome Interacting Protein Deficiency Uncovers the Role of the Co-receptor CD19 as a Generic Hub for PI3 Kinase Signaling in B Cells.

Wiskott-Aldrich syndrome protein deficiency in B cells results in impaired peripheral homeostasis