List of works - Francesco Tisato

A novel copper complex induces paraptosis in colon cancer cells via the activation of ER stress signalling

scientific article

Advances in copper complexes as anticancer agents

scientific article published on 08 October 2013

An 86Y-labeled mirror-image oligonucleotide: influence of Y-DOTA isomers on the biodistribution in rats

scientific article

Asymmetrical nitrido tc-99m heterocomplexes as potential imaging agents for benzodiazepine receptors

scientific article published in November 2003

Attentive Monitoring of Multiple Video Streams Driven by a Bayesian Foraging Strategy. ⬇️

scientific article published on 8 May 2015

Avidin-biotin system: a small library of cysteine biotinylated derivatives designed for the [99mTc(N)(PNP)]2+ metal fragment.

scientific article

Cancer cell death induced by phosphine gold(I) compounds targeting thioredoxin reductase

scientific article

Characterisation via electrospray ionisation multistage mass spectrometry of three related series of nitrido technetium complexes containing phosphinothiolate and dithiocarbamate ligands

scientific article published in January 2005

Characterization of the designer drug deschloroketamine (2-methylamino-2-phenylcyclohexanone) by gas chromatography/mass spectrometry, liquid chromatography/high-resolution mass spectrometry, multistage mass spectrometry, and nuclear magnetic resona

scientific article

Chelated hydrazido(3-)rhenium(V) complexes: on the way to the nitrido-M(V) core (M = Tc, Re).

scientific article published in March 2002

Chemistry of the strong electrophilic metal fragment [(99)Tc(N)(PXP)](2+) (PXP = diphosphine ligand). A novel tool for the selective labeling of small molecules.

scientific article published in September 2002

Contribution of electrospray mass spectrometry for the characterization, design, and development of nitrido technetium and rhenium heterocomplexes as potential radiopharmaceuticals.

scientific article published in September 2004

Coordinative unsaturated CuI entities are crucial intermediates governing cell internalization of copper. A combined experimental ESI-MS and DFT study

scientific article published on 28 October 2019

Copper complexes as anticancer agents

scientific article published on February 2009

Copper in diseases and treatments, and copper-based anticancer strategies.

scientific article published on July 2010

Copper(I) complexes with phosphines P(p-OCH3-Ph)2CH2OH and P(p-OCH3-Ph)2CH2SarGly. Synthesis, multimodal DNA interactions, and prooxidative and in vitro antiproliferative activity

scientific article published on 15 November 2019

Cu(i) and Ag(i) complex formation with the hydrophilic phosphine 1,3,5-triaza-7-phosphadamantane in different ionic media. How to estimate the effect of a complexing medium.

scientific article published on 11 January 2017

Cytotoxicity in human cancer cells and mitochondrial dysfunction induced by a series of new copper(I) complexes containing tris(2-cyanoethyl)phosphines.

scientific article published on 22 June 2010

Electrospray ionization in the study of the interactions between cytotoxic phosphino Cu(I) complexes and selected amino acids and GlyGlyHis peptide model

scientific article published in January 2016

Electrospray ionization mass spectrometry in the structural characterization of a mixed nitrido-Tc heterocomplex of interest for myocardial imaging

scientific article published on 01 January 2003

Electrospray ionization multi-stage mass spectrometric study of the interaction products of the cytotoxic complex [Cu(thp)₄][PF₆] with methionine-rich model peptides.

scientific article published in February 2015

Electrospray ionization study of tricarbonyl fac-[Re(CO)3 (PO)(X)]-type complexes: influence of ancillary co-ligands in the release of carbon monoxide

scientific article published on 01 August 2018

Electrospray mass spectrometry of a series of mixed nitrido 99gTc- heterocomplexes conjugated with bioactive molecules.

scientific article published in January 2004

Evidence of noncovalent complexes in some natural extracts: Ceylon tea and mate extracts

scientific article published on 29 October 2019

From symmetrical to asymmetrical nitrido phosphino-thiol complexes: a new class of neutral mixed-ligand (99m)Tc compounds as potential brain imaging agents

scientific article published in March 2006

In vitro and in vivo anticancer activity of copper(I) complexes with homoscorpionate tridentate tris(pyrazolyl)borate and auxiliary monodentate phosphine ligands.

scientific article published on 15 May 2014

In vitro antitumor activity of the water soluble copper(I) complexes bearing the tris(hydroxymethyl)phosphine ligand.

scientific article published on 6 February 2008

In vitro antitumour activity of water soluble Cu(I), Ag(I) and Au(I) complexes supported by hydrophilic alkyl phosphine ligands.

scientific article published on 5 November 2010

Insights into the cytotoxic activity of the phosphane copper(I) complex [Cu(thp)4][PF6].

scientific article published on 8 July 2016

Insights into the failure of the potential, neutral myocardial imaging agent TcN-NOET: physicochemical identification of by-products and degradation species

scientific article published on 01 December 2011

Interaction products of cytotoxic Cu(I) complexes with different solvent mixtures: an electrospray ionization mass spectrometry and density functional theory study

scientific article published on 2 November 2016

Methylselenol formed by spontaneous methylation of selenide is a superior selenium substrate to the thioredoxin and glutaredoxin systems

scientific article published in 2012

Mixed-ligand rhenium-188 complexes with tetradentate/monodentate NS3/P ('4 + 1') coordination: relation of structure with antioxidation stability

scientific article published in May 2005

Neutral and charged phosphine/scorpionate copper(I) complexes: effects of ligand assembly on their antiproliferative activity.

scientific article published on 23 November 2012

New approach to the chemistry of technetium(V) and rhenium(V) phenylimido complexes: novel [M(NPh)PNP]3+ metal fragments (M = Tc, Re; PNP = aminodiphosphine) suitable for the synthesis of stable mixed-ligand compounds

scientific article published in June 2005

New copper(I) phosphane complexes of dihydridobis(3-nitro-1,2,4-triazolyl)borate ligand showing cytotoxic activity.

scientific article published on 4 January 2006

New insights in Au-NHCs complexes as anticancer agents.

scientific article published on 31 January 2018

Novel mixed-ligand copper(I) complexes: role of diimine ligands on cytotoxicity and genotoxicity

scientific article published on 10 September 2013

Novel rhenium(V) oxo complexes containing bis(pyrazol-1-yl)acetate and bis(pyrazol-1-yl) sulfonate as tripodal N,N,O-heteroscorpionate ligands

scientific article published in May 2005

Phthalates and heavy metals as endocrine disruptors in food: A study on pre-packed coffee products

scientific article published on 17 May 2017

Rhenium(I) Tricarbonyl Complexes with (2-Hydroxyphenyl)diphenylphosphine as PO Bidentate Ligand

scientific article

Syntheses and reactivity of 'sulfur rich' Re(iii) and Tc(iii) complexes containing trithioperoxybenzoate, dithiobenzoate and dithiocarbamate ligands.

scientific article published on 19 July 2005

Synthesis and Characterization of Nitrido Tc(V) and Re(V) Complexes with Ferrocenedithiocarboxylate {FcCS(2) = [Fe(C(5)H(4)CS(2))(C(5)H(5))](-)}

scientific article published in August 1997

Synthesis and structural characterization of copper(I) complexes bearing N-methyl-1,3,5-triaza-7-phosphaadamantane (mPTA): cytotoxic activity evaluation of a series of water soluble Cu(I) derivatives containing PTA, PTAH and mPTA ligands

scientific article published on 13 September 2009

Synthesis of a Novel Class of Trigonal Bipyramidal Nitrido Tc(V) Complexes with Phosphino-Thiol Ligands. Crystal Structure of [(99g)Tc(N)(L(1))(2)] [L(1) = 2-(Diphenylphosphino)ethanethiolato] and [(99g)Tc(N)(L(5))(2)] [L(5) = 2-(Ditolylphosphino)pr

scientific article published on 01 October 1999

Synthesis, characterization, and biological evaluation of neutral nitrido technetium(V) mixed ligand complexes containing dithiolates and aminodiphosphines. A novel system for linking technetium to biomolecules

scientific article

Synthesis, characterization, and biological evaluation of technetium(III) complexes with tridentate/bidentate S,E,S/P,S coordination (E = O, N(CH(3)), S): a novel approach to robust technetium chelates suitable for linking the metal to biomolecules

scientific article published in January 2003

Synthesis, characterization, and in vitro antitumor properties of tris(hydroxymethyl)phosphine copper(I) complexes containing the new bis(1,2,4-triazol-1-yl)acetate ligand

scientific article published on December 2006

Synthesis, in vitro and in vivo characterization of (64)Cu(I) complexes derived from hydrophilic tris(hydroxymethyl)phosphane and 1,3,5-triaza-7-phosphaadamantane ligands.

scientific article published on 27 November 2007

Technetium and rhenium in five-coordinate symmetrical and dissymmetrical nitrido complexes with alkyl phosphino-thiol ligands. Synthesis and structural characterization.

scientific article

The crucial role of the diphosphine heteroatom X in the stereochemistry and stabilization of the substitution-inert [M(N)(PXP)]2+ metal fragments (M = Tc, Re; PXP = diphosphine ligand)

scientific article published on 01 December 2004

The relationship between electrospray ionization behavior and cytotoxic activity of [M(I)(P)4](+)-type complexes (M = Cu, Ag and Au; P = tertiary phosphine).

scientific article published on September 2013

The relationship between the electrospray ionization behaviour and biological activity of some phosphino Cu(I) complexes

scientific article published on 01 June 2010

Therapeutic potential of the phosphino Cu(I) complex (HydroCuP) in the treatment of solid tumors.

scientific article published on 24 October 2017

List of works by Francesco Tisato

A novel copper complex induces paraptosis in colon cancer cells via the activation of ER stress signalling

Advances in copper complexes as anticancer agents

An 86Y-labeled mirror-image oligonucleotide: influence of Y-DOTA isomers on the biodistribution in rats

Asymmetrical nitrido tc-99m heterocomplexes as potential imaging agents for benzodiazepine receptors

Attentive Monitoring of Multiple Video Streams Driven by a Bayesian Foraging Strategy. ⬇️

Avidin-biotin system: a small library of cysteine biotinylated derivatives designed for the [99mTc(N)(PNP)]2+ metal fragment.

Cancer cell death induced by phosphine gold(I) compounds targeting thioredoxin reductase

Characterisation via electrospray ionisation multistage mass spectrometry of three related series of nitrido technetium complexes containing phosphinothiolate and dithiocarbamate ligands

Characterization of the designer drug deschloroketamine (2-methylamino-2-phenylcyclohexanone) by gas chromatography/mass spectrometry, liquid chromatography/high-resolution mass spectrometry, multistage mass spectrometry, and nuclear magnetic resona

Chelated hydrazido(3-)rhenium(V) complexes: on the way to the nitrido-M(V) core (M = Tc, Re).

Chemistry of the strong electrophilic metal fragment [(99)Tc(N)(PXP)](2+) (PXP = diphosphine ligand). A novel tool for the selective labeling of small molecules.

Contribution of electrospray mass spectrometry for the characterization, design, and development of nitrido technetium and rhenium heterocomplexes as potential radiopharmaceuticals.

Coordinative unsaturated CuI entities are crucial intermediates governing cell internalization of copper. A combined experimental ESI-MS and DFT study

Copper complexes as anticancer agents

Copper in diseases and treatments, and copper-based anticancer strategies.

Copper(I) complexes with phosphines P(p-OCH3-Ph)2CH2OH and P(p-OCH3-Ph)2CH2SarGly. Synthesis, multimodal DNA interactions, and prooxidative and in vitro antiproliferative activity

Cu(i) and Ag(i) complex formation with the hydrophilic phosphine 1,3,5-triaza-7-phosphadamantane in different ionic media. How to estimate the effect of a complexing medium.

Cytotoxicity in human cancer cells and mitochondrial dysfunction induced by a series of new copper(I) complexes containing tris(2-cyanoethyl)phosphines.

Electrospray ionization in the study of the interactions between cytotoxic phosphino Cu(I) complexes and selected amino acids and GlyGlyHis peptide model

Electrospray ionization mass spectrometry in the structural characterization of a mixed nitrido-Tc heterocomplex of interest for myocardial imaging

Electrospray ionization multi-stage mass spectrometric study of the interaction products of the cytotoxic complex [Cu(thp)₄][PF₆] with methionine-rich model peptides.

Electrospray ionization study of tricarbonyl fac-[Re(CO)3 (PO)(X)]-type complexes: influence of ancillary co-ligands in the release of carbon monoxide

Electrospray mass spectrometry of a series of mixed nitrido 99gTc- heterocomplexes conjugated with bioactive molecules.

Evidence of noncovalent complexes in some natural extracts: Ceylon tea and mate extracts

From symmetrical to asymmetrical nitrido phosphino-thiol complexes: a new class of neutral mixed-ligand (99m)Tc compounds as potential brain imaging agents

In vitro and in vivo anticancer activity of copper(I) complexes with homoscorpionate tridentate tris(pyrazolyl)borate and auxiliary monodentate phosphine ligands.

In vitro antitumor activity of the water soluble copper(I) complexes bearing the tris(hydroxymethyl)phosphine ligand.

In vitro antitumour activity of water soluble Cu(I), Ag(I) and Au(I) complexes supported by hydrophilic alkyl phosphine ligands.

Insights into the cytotoxic activity of the phosphane copper(I) complex [Cu(thp)4][PF6].

Insights into the failure of the potential, neutral myocardial imaging agent TcN-NOET: physicochemical identification of by-products and degradation species

Interaction products of cytotoxic Cu(I) complexes with different solvent mixtures: an electrospray ionization mass spectrometry and density functional theory study

Methylselenol formed by spontaneous methylation of selenide is a superior selenium substrate to the thioredoxin and glutaredoxin systems

Mixed-ligand rhenium-188 complexes with tetradentate/monodentate NS3/P ('4 + 1') coordination: relation of structure with antioxidation stability

Neutral and charged phosphine/scorpionate copper(I) complexes: effects of ligand assembly on their antiproliferative activity.

New approach to the chemistry of technetium(V) and rhenium(V) phenylimido complexes: novel [M(NPh)PNP]3+ metal fragments (M = Tc, Re; PNP = aminodiphosphine) suitable for the synthesis of stable mixed-ligand compounds

New copper(I) phosphane complexes of dihydridobis(3-nitro-1,2,4-triazolyl)borate ligand showing cytotoxic activity.

New insights in Au-NHCs complexes as anticancer agents.

Novel mixed-ligand copper(I) complexes: role of diimine ligands on cytotoxicity and genotoxicity

Novel rhenium(V) oxo complexes containing bis(pyrazol-1-yl)acetate and bis(pyrazol-1-yl) sulfonate as tripodal N,N,O-heteroscorpionate ligands

Phthalates and heavy metals as endocrine disruptors in food: A study on pre-packed coffee products

Rhenium(I) Tricarbonyl Complexes with (2-Hydroxyphenyl)diphenylphosphine as PO Bidentate Ligand

Syntheses and reactivity of 'sulfur rich' Re(iii) and Tc(iii) complexes containing trithioperoxybenzoate, dithiobenzoate and dithiocarbamate ligands.

Synthesis and Characterization of Nitrido Tc(V) and Re(V) Complexes with Ferrocenedithiocarboxylate {FcCS(2) = [Fe(C(5)H(4)CS(2))(C(5)H(5))](-)}

Synthesis and structural characterization of copper(I) complexes bearing N-methyl-1,3,5-triaza-7-phosphaadamantane (mPTA): cytotoxic activity evaluation of a series of water soluble Cu(I) derivatives containing PTA, PTAH and mPTA ligands

Synthesis of a Novel Class of Trigonal Bipyramidal Nitrido Tc(V) Complexes with Phosphino-Thiol Ligands. Crystal Structure of [(99g)Tc(N)(L(1))(2)] [L(1) = 2-(Diphenylphosphino)ethanethiolato] and [(99g)Tc(N)(L(5))(2)] [L(5) = 2-(Ditolylphosphino)pr

Synthesis, characterization, and biological evaluation of neutral nitrido technetium(V) mixed ligand complexes containing dithiolates and aminodiphosphines. A novel system for linking technetium to biomolecules

Synthesis, characterization, and biological evaluation of technetium(III) complexes with tridentate/bidentate S,E,S/P,S coordination (E = O, N(CH(3)), S): a novel approach to robust technetium chelates suitable for linking the metal to biomolecules

Synthesis, characterization, and in vitro antitumor properties of tris(hydroxymethyl)phosphine copper(I) complexes containing the new bis(1,2,4-triazol-1-yl)acetate ligand

Synthesis, in vitro and in vivo characterization of (64)Cu(I) complexes derived from hydrophilic tris(hydroxymethyl)phosphane and 1,3,5-triaza-7-phosphaadamantane ligands.

Technetium and rhenium in five-coordinate symmetrical and dissymmetrical nitrido complexes with alkyl phosphino-thiol ligands. Synthesis and structural characterization.

The crucial role of the diphosphine heteroatom X in the stereochemistry and stabilization of the substitution-inert [M(N)(PXP)]2+ metal fragments (M = Tc, Re; PXP = diphosphine ligand)

The relationship between electrospray ionization behavior and cytotoxic activity of [M(I)(P)4](+)-type complexes (M = Cu, Ag and Au; P = tertiary phosphine).

The relationship between the electrospray ionization behaviour and biological activity of some phosphino Cu(I) complexes

Therapeutic potential of the phosphino Cu(I) complex (HydroCuP) in the treatment of solid tumors.

Thermodynamic stability and structure in aqueous solution of the [Cu(PTA)] complex (PTA = aminophosphine‑1,3,5‑triaza‑7‑phosphaadamantane)

Thermodynamic stability and structure in aqueous solution of the [Cu(PTA)] complex (PTA = aminophosphine‑1,3,5‑triaza‑7‑phosphaadamantane)