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List of works by Drew Weissman

2772. HCMV gB Ectodomain Subunit and gB mRNA Vaccines Reduce AD-3 Immunodominance and Elicit More Durable Antibody Responses Than gB/MF59 Immunization

scientific article published on 23 October 2019

A Common NLRC4 Gene Variant Associates With Inflammation and Pulmonary Function in Human Immunodeficiency Virus and Tuberculosis

scientific article published on 22 November 2019

A Multi-Targeting, Nucleoside-Modified mRNA Influenza Virus Vaccine Provides Broad Protection in Mice

scientific article published on 19 April 2020

A Single Immunization with Nucleoside-Modified mRNA Vaccines Elicits Strong Cellular and Humoral Immune Responses against SARS-CoV-2 in Mice

scientific article published on 30 July 2020

A membrane-proximal basic domain and cysteine cluster in the C-terminal tail of CCR5 constitute a bipartite motif critical for cell surface expression

scientific article published on 20 August 2001

A molecular tweezer antagonizes seminal amyloids and HIV infection.

scientific article

A multivalent nucleoside-modified mRNA vaccine against all known influenza virus subtypes

scientific article published on 25 November 2022

A platelet-activating factor antagonist, RP 55778, inhibits cytokine-dependent induction of human immunodeficiency virus expression in chronically infected promonocytic cells ⬇️

scientific article published on March 15, 1993

Acute Biological Effects of Simulating the Whole-Body Radiation Dose Distribution from a Solar Particle Event Using a Porcine Model ⬇️

scientific article published on August 22, 2011

Acute effects of solar particle event radiation.

scientific article published in March 2014

Administration of nucleoside-modified mRNA encoding broadly neutralizing antibody protects humanized mice from HIV-1 challenge

scientific article published on 02 March 2017

An HSV-2 nucleoside-modified mRNA genital herpes vaccine containing glycoproteins gC, gD, and gE protects mice against HSV-1 genital lesions and latent infection

scientific article published on 27 July 2020

An electrochemiluminescence assay for gp340 (DMBT1).

scientific article published on 30 May 2013

Anti-PfGARP activates programmed cell death of parasites and reduces severe malaria

scientific article published on 22 April 2020

Antiviral activities in human saliva

scientific article

Both a precursor and a mature population of dendritic cells can bind HIV. However, only the mature population that expresses CD80 can pass infection to unstimulated CD4+ T cells

scientific article

Breast tumors interfere with endothelial TRAIL at the premetastatic niche to promote cancer cell seeding

scientific article published in 2023

Broad-spectrum antibiotic or G-CSF as potential countermeasures for impaired control of bacterial infection associated with an SPE exposure during spaceflight

scientific article

CAR T cells produced in vivo to treat cardiac injury

scientific article published on 7 January 2022

Characterization of HIV-1 Nucleoside-Modified mRNA Vaccines in Rabbits and Rhesus Macaques

article

Chronic inflammation with increased human immunodeficiency virus (HIV) RNA expression in the vaginal epithelium of HIV-infected Thai women

scientific article published on 16 July 2001

Common Variation in NLRP3 Is Associated With Early Death and Elevated Inflammasome Biomarkers Among Advanced HIV/TB Co-infected Patients in Botswana.

scientific article

Constitutive and induced expression of DC-SIGN on dendritic cell and macrophage subpopulations in situ and in vitro

scientific article published on 01 March 2002

Cutting edge: innate immune system discriminates between RNA containing bacterial versus eukaryotic structural features that prime for high-level IL-12 secretion by dendritic cells

scientific article published on April 2004

Cytokine regulation of HIV replication induced by dendritic cell-CD4-positive T cell interactions

scientific article published on 01 June 1996

D614G Spike Mutation Increases SARS CoV-2 Susceptibility to Neutralization

scientific article published on 01 December 2020

Declines in Lung Function After Antiretroviral Therapy Initiation in Adults With Human Immunodeficiency Virus and Tuberculosis: A Potential Manifestation of Respiratory Immune Reconstitution Inflammatory Syndrome

scientific article published on 01 April 2020

Dendritic Cells Express and Use Multiple HIV Coreceptors ⬇️

scientific article published on 01 January 1997

Dendritic cells express multiple chemokine receptors used as coreceptors for HIV entry ⬇️

scientific article published on April 15, 1998

Differential N-linked glycosylation of human immunodeficiency virus and Ebola virus envelope glycoproteins modulates interactions with DC-SIGN and DC-SIGNR

scientific article

Direct Delivery of mRNA-Loaded Lipid Nanoparticles to the Hematopoietic Stem Cell Niche

scientific article published in 2022

Early immunologic failure is associated with early mortality among advanced HIV-infected adults initiating antiretroviral therapy with active tuberculosis

scientific article published on August 2013

Early versus delayed antiretroviral therapy and cerebrospinal fluid fungal clearance in adults with HIV and cryptococcal meningitis

scientific article

Effect of GB virus C viremia on HIV acquisition and HIV set-point.

scientific article published in November 2005

Effect of Mycobacterium tuberculosis on HIV replication. Role of immune activation

scientific article published on 01 August 1996

Effect of Solar Particle Event Radiation and Hindlimb Suspension on Gastrointestinal Tract Bacterial Translocation and Immune Activation ⬇️

scientific article published on September 19, 2012

Effect of Solar Particle Event Radiation on Gastrointestinal Tract Bacterial Translocation and Immune Activation ⬇️

scientific article published on February 4, 2011

Elevated Pre-Antiretroviral Therapy CD39+CD8+ T Cell Frequency Is Associated With Early Mortality in Advanced Human Immunodeficiency Virus/Tuberculosis Co-infection

scientific article published on 16 February 2017

Epigallocatechin-3-gallate rapidly remodels PAP85-120, SEM1(45-107), and SEM2(49-107) seminal amyloid fibrils.

scientific article

Evaluation of a Single-Dose Nucleoside-Modified Messenger RNA Vaccine Encoding Hendra Virus-Soluble Glycoprotein Against Lethal Nipah virus Challenge in Syrian Hamsters

scientific article published on 21 November 2019

Exogenous siRNA mediates sequence-independent gene suppression by signaling through toll-like receptor 3.

scientific article published on January 2004

Expression kinetics of nucleoside-modified mRNA delivered in lipid nanoparticles to mice by various routes

scientific article

Extracellular mRNA induces dendritic cell activation by stimulating tumor necrosis factor-alpha secretion and signaling through a nucleotide receptor

scientific article published on 30 January 2002

Generating the optimal mRNA for therapy: HPLC purification eliminates immune activation and improves translation of nucleoside-modified, protein-encoding mRNA ⬇️

scientific article published on September 2, 2011

HCMV glycoprotein B nucleoside-modified mRNA vaccine elicits antibody responses with greater durability and breadth than MF59-adjuvanted gB protein immunization

scientific article published on 12 February 2020

HIV envelope binding by macrophage-expressed gp340 promotes HIV-1 infection.

scientific article published on August 2008

HIV envelope suppresses CD4+ T cell activation independent of T regulatory cells

scientific article

HIV gag mRNA transfection of dendritic cells (DC) delivers encoded antigen to MHC class I and II molecules, causes DC maturation, and induces a potent human in vitro primary immune response

scientific article published in October 2000

HIV replication in CD4+ T cells of HIV-infected individuals is regulated by a balance between the viral suppressive effects of endogenous beta-chemokines and the viral inductive effects of other endogenous cytokines

scientific article

HPLC Purification of In Vitro Transcribed Long RNA ⬇️

scientific article published on January 1, 2013

Hindlimb suspension and SPE-like radiation impairs clearance of bacterial infections

scientific article published on 15 January 2014

IL-10 synergizes with multiple cytokines in enhancing HIV production in cells of monocytic lineage

scientific article published on August 1995

Identification of Cyclobutane Pyrimidine Dimer-Responsive Genes Using UVB-Irradiated Human Keratinocytes Transfected with In Vitro-Synthesized Photolyase mRNA.

scientific article published on 29 June 2015

Identification of multiple and distinct CD8+ T cell suppressor activities: dichotomy between infected and uninfected individuals, evolution with progression of disease, and sensitivity to gamma irradiation

scientific article published on 01 June 1996

Immune reconstitution

scientific article

Immunological profiling of tuberculosis-associated immune reconstitution inflammatory syndrome and non-immune reconstitution inflammatory syndrome death in HIV-infected adults with pulmonary tuberculosis starting antiretroviral therapy: a prospectiv

scientific article

Immunopathogenic mechanisms of HIV infection

scientific article published on 01 April 1996

In Vitro Transcription of Long RNA Containing Modified Nucleosides ⬇️

scientific article published on January 1, 2013

In Vivo Identification of Langerhans and Related Dendritic Cells Infected with HIV-1 Subtype E in Vaginal Mucosa of Asymptomatic Patients ⬇️

scientific article published on 01 December 2001

In vivo adenine base editing of PCSK9 in macaques reduces LDL cholesterol levels

scientific article

In vivo hematopoietic stem cell modification by mRNA delivery

scientific article published on 27 July 2023

Incorporation of pseudouridine into mRNA enhances translation by diminishing PKR activation

scientific article

Incorporation of pseudouridine into mRNA yields superior nonimmunogenic vector with increased translational capacity and biological stability

scientific article published on 16 September 2008

Increased erythropoiesis in mice injected with submicrogram quantities of pseudouridine-containing mRNA encoding erythropoietin

scientific article

Increased surface expression of HIV-1 envelope is associated with improved antibody response in vaccinia prime/protein boost immunization

scientific article published on 22 November 2017

Induction of HIV-specific T and B cell responses with a replicating and conditionally infectious lentiviral vaccine

scientific article published on 01 May 2008

Inherited resistance to HIV-1 conferred by an inactivating mutation in CC chemokine receptor 5: studies in populations with contrasting clinical phenotypes, defined racial background, and quantified risk

scientific article

Inhibition of HIV-1 infection by small interfering RNA-mediated RNA interference

scientific article published on November 2002

Inhibition of toll-like receptor and cytokine signaling--a unifying theme in ischemic tolerance

scientific article

Interleukin 10 blocks HIV replication in macrophages by inhibiting the autocrine loop of tumor necrosis factor alpha and interleukin 6 induction of virus

scientific article

Interleukin-2 up-regulates expression of the human immunodeficiency virus fusion coreceptor CCR5 by CD4+ lymphocytes in vivo

scientific article published in March 2000

Ionizing radiation selectively reduces skin regulatory T cells and alters immune function

scientific article (publication date: 2014)

Isoniazid clearance is impaired among human immunodeficiency virus/tuberculosis patients with high levels of immune activation

scientific article published on 28 October 2016

Lipid nanoparticle encapsulated nucleoside-modified mRNA vaccines elicit polyfunctional HIV-1 antibodies comparable to proteins in nonhuman primates

scientific article published on 31 December 2020

Lipid nanoparticles enhance the efficacy of mRNA and protein subunit vaccines by inducing robust T follicular helper cell and humoral responses

scientific article published on 04 November 2021

Lung Injury on Antiretroviral Therapy in Adults With Human Immunodeficiency Virus/Tuberculosis

scientific article published on 26 June 2019

Macrophage-tropic HIV and SIV envelope proteins induce a signal through the CCR5 chemokine receptor ⬇️

scientific article published on October 30, 1997

Markers of gut dysfunction do not explain low rifampicin bioavailability in HIV-associated TB.

scientific article published on 2 May 2017

Matrix Metalloproteinases in Tuberculosis-Immune Reconstitution Inflammatory Syndrome and Impaired Lung Function Among Advanced HIV/TB Co-infected Patients Initiating Antiretroviral Therapy

scientific article

Measuring the Adjuvant Activity of RNA Vaccines

scientific article published on January 2017

Messenger RNA-Based Vaccines Against Infectious Diseases

scientific article published on 17 April 2020

Multifactorial nature of noncytolytic CD8+ T cell-mediated suppression of HIV replication: beta-chemokine-dependent and -independent effects

scientific article published on January 1997

Naturally occurring nucleoside modifications suppress the immunostimulatory activity of RNA: implication for therapeutic RNA development.

scientific article published on September 2007

Neutralizing antibody vaccine for pandemic and pre-emergent coronaviruses

scientific article

Nonproliferating bystander CD4+ T cells lacking activation markers support HIV replication during immune activation

scientific article published on 01 May 2001

Nucleofection induces transient eIF2α phosphorylation by GCN2 and PERK ⬇️

scientific article published on February 2, 2012

Nucleoside Modified mRNA Vaccines for Infectious Diseases

scientific article published on January 2017

Nucleoside modifications in RNA limit activation of 2'-5'-oligoadenylate synthetase and increase resistance to cleavage by RNase L ⬇️

scientific article published on August 3, 2011

Nucleoside-Modified mRNA Vaccines Protect IFNAR<sup>-/-</sup> Mice against Crimean-Congo Hemorrhagic Fever Virus Infection

scientific article published on 24 November 2021

Nucleoside-modified mRNA encoding HSV-2 glycoproteins C, D, and E prevents clinical and subclinical genital herpes

scientific article published on 01 September 2019

Nucleoside-modified mRNA immunization elicits influenza virus hemagglutinin stalk-specific antibodies

scientific article published in Nature Communications

Nucleoside-modified mRNA vaccination partially overcomes maternal antibody inhibition of de novo immune responses in mice

scientific article published on 01 January 2020

Nucleoside-modified mRNA vaccines induce potent T follicular helper and germinal center B cell responses.

scientific article

Optimizing ethambutol dosing among HIV/tuberculosis co-infected patients: a population pharmacokinetic modelling and simulation study

scientific article published on 01 October 2019

PECAM-1 directed re-targeting of exogenous mRNA providing two orders of magnitude enhancement of vascular delivery and expression in lungs independent of apolipoprotein E-mediated uptake

scientific article published on 15 October 2018

Periluminal Distribution of HIV-Binding Target Cells and Gp340 in the Oral, Cervical and Sigmoid/Rectal Mucosae: A Mapping Study

scientific article published on 14 July 2015

Protection against herpes simplex virus type 2 infection in a neonatal murine model using a trivalent nucleoside-modified mRNA in lipid nanoparticle vaccine

scientific article published on 08 October 2020

Purification of mRNA Encoding Chimeric Antigen Receptor Is Critical for Generation of a Robust T-Cell Response

scientific article published on 02 October 2018

Pyrazinamide clearance is impaired among HIV/tuberculosis patients with high levels of systemic immune activation.

scientific article published on 2 November 2017

RNA based vaccines

scientific article

Recent advances in mRNA vaccine technology

scientific article published on 31 March 2020

Reduced cell surface expression of CCR5 in CCR5Delta 32 heterozygotes is mediated by gene dosage, rather than by receptor sequestration

scientific article published on 16 October 2001

Repurposing Hsp104 to Antagonize Seminal Amyloid and Counter HIV Infection.

scientific article published on 3 August 2015

Robust Reconstitution of Tuberculosis-Specific Polyfunctional CD4+ T-Cell Responses and Rising Systemic Interleukin 6 in Paradoxical Tuberculosis-Associated Immune Reconstitution Inflammatory Syndrome

scientific article published on 26 November 2015

Role of dendritic cells in immunopathogenesis of human immunodeficiency virus infection

scientific article

SARS-CoV-2 mRNA Vaccines Foster Potent Antigen-Specific Germinal Center Responses Associated with Neutralizing Antibody Generation

scientific article published on 21 November 2020

SIV antigen immunization induces transient antigen-specific T cell responses and selectively activates viral replication in draining lymph nodes in retroviral suppressed rhesus macaques ⬇️

scientific article published on July 13, 2011

Selective targeting of nanomedicine to inflamed cerebral vasculature to enhance the blood-brain barrier

scientific article published on 31 January 2020

Short Communication: The Role of Dendritic Cells in the Infection of CD4+T Cells with the Human Immunodeficiency Virus: Use of Dendritic Cells from Individuals Homozygous for the Δ32CCR5Allele as a Model ⬇️

scientific article published on September 1, 1998

Short interfering RNA-mediated inhibition of herpes simplex virus type 1 gene expression and function during infection of human keratinocytes

scientific article

Small interfering RNAs mediate sequence-independent gene suppression and induce immune activation by signaling through toll-like receptor 3.

scientific article published in June 2004

Suppression of RNA recognition by Toll-like receptors: the impact of nucleoside modification and the evolutionary origin of RNA

scientific article

Synthesis of random copolymer based pH-responsive nanoparticles as drug carriers for cancer therapeutics

The Chronically Infected Promonocytic Cell Line U1: A Model of HIV Expression Regulated by Cytokines

article

The N-terminal SRCR-SID domain of gp-340 interacts with HIV type 1 gp120 sequences and inhibits viral infection

scientific article published on June 2006

The Transcription Factor T-bet Resolves Memory B Cell Subsets with Distinct Tissue Distributions and Antibody Specificities in Mice and Humans

scientific article published on 22 April 2020

The efficiency of acute infection of CD4+ T cells is markedly enhanced in the setting of antigen-specific immune activation

scientific article

The in vitro induction of human immunodeficiency virus (HIV) replication in purified protein derivative-positive HIV-infected persons by recall antigen response to Mycobacterium tuberculosis is the result of a balance of the effects of endogenous in

scientific article published in May 1998

Three populations of cells with dendritic morphology exist in peripheral blood, only one of which is infectable with human immunodeficiency virus type 1.

scientific article

Transfection of pseudouridine-modified mRNA encoding CPD-photolyase leads to repair of DNA damage in human keratinocytes: a new approach with future therapeutic potential

scientific article published on 11 October 2013

Tuberculosis and lung damage: from epidemiology to pathophysiology.

scientific article

Upregulation of the phthiocerol dimycocerosate biosynthetic pathway by rifampin-resistant, rpoB mutant Mycobacterium tuberculosis

scientific article

Vaccinating HIV patients: focus on human papillomavirus and herpes zoster vaccines

scientific article published on April 1, 2013

Vaccination with Messenger RNA: A Promising Alternative to DNA Vaccination

scientific article published on 01 January 2021

Vaccine innovations for emerging infectious diseases-a symposium report

scientific article published on 28 October 2019

Vaccine-delivered HIV envelope inhibits CD4(+) T-cell activation, a mechanism for poor HIV vaccine responses

scientific article published on 7 December 2006

Zika virus protection by a single low-dose nucleoside-modified mRNA vaccination

scientific article

gp340 expressed on human genital epithelia binds HIV-1 envelope protein and facilitates viral transmission

scientific article published in September 2007

gp340 promotes transcytosis of human immunodeficiency virus type 1 in genital tract-derived cell lines and primary endocervical tissue

scientific article published on 24 June 2009

mRNA is an endogenous ligand for Toll-like receptor 3.

scientific article

mRNA transcript therapy

scientific article published on 31 October 2014

mRNA vaccines - a new era in vaccinology

scientific article published on 12 January 2018

mRNA vaccines for infectious diseases: principles, delivery and clinical translation

scientific article

mRNA: Fulfilling the Promise of Gene Therapy

scientific article published on September 2015

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