Search filters

List of works by Katalin Karikó

2- and 8-azido photoaffinity probes. 1. Enzymatic synthesis, characterization, and biological properties of 2- and 8-azido photoprobes of 2-5A and photolabeling of 2-5A binding proteins

scientific article

A Facile Method for the Removal of dsRNA Contaminant from In Vitro-Transcribed mRNA

A Single Immunization with Nucleoside-Modified mRNA Vaccines Elicits Strong Cellular and Humoral Immune Responses against SARS-CoV-2 in Mice

scientific article published on 30 July 2020

A noninflammatory mRNA vaccine for treatment of experimental autoimmune encephalomyelitis

scientific article published on 01 January 2021

A systematic dissection of determinants and consequences of snoRNA-guided pseudouridylation of human mRNA

scientific article published on 10 May 2022

ASL mRNA-LNP Therapeutic for the Treatment of Argininosuccinic Aciduria Enables Survival Benefit in a Mouse Model

scientific article published on 16 June 2023

Administration of nucleoside-modified mRNA encoding broadly neutralizing antibody protects humanized mice from HIV-1 challenge

scientific article published on 02 March 2017

Autologous blood injection to model spontaneous intracerebral hemorrhage in mice

scientific article published on 24 August 2011

BNT162b2 vaccine induces neutralizing antibodies and poly-specific T cells in humans

scientific article published on 27 May 2021

COVID-19 vaccine BNT162b1 elicits human antibody and TH1 T-cell responses

scientific article published on 30 September 2020

Cerebral preconditioning using cortical application of hypertonic salt solutions: upregulation of mRNAs encoding inhibitors of inflammation ⬇️

scientific article published on 24 May 2006

Characterization of HIV-1 Nucleoside-Modified mRNA Vaccines in Rabbits and Rhesus Macaques

article

Characterization of human endothelial cell urokinase-type plasminogen activator receptor protein and messenger RNA.

scientific article

Characterization of urokinase receptor expression by human placental trophoblasts ⬇️

scientific article published on June 1, 1992

Concurrent human antibody and TH1 type T-cell responses elicited by a COVID-19 RNA vaccine

preprint

Cutting edge: innate immune system discriminates between RNA containing bacterial versus eukaryotic structural features that prime for high-level IL-12 secretion by dendritic cells

scientific article published on April 2004

DICER1 deficit induces Alu RNA toxicity in age-related macular degeneration

scientific article

Decreased Epstein-Barr virus-induced transformation, and elevated 2-5A synthetase and RNase L activity in peripheral blood mononuclear cells from patients treated with recombinant interferon alfa 2b.

scientific article

Defensin Modulates Tissue-type Plasminogen Activator and Plasminogen Binding to Fibrin and Endothelial Cells

scientific article published in Journal of Biological Chemistry

Dose-dependent induction of mRNAs encoding brain-derived neurotrophic factor and heat-shock protein-72 after cortical spreading depression in the rat.

scientific article

Effect of cortical spreading depression on the levels of mRNA coding for putative neuroprotective proteins in rat brain

scientific article published in December 1998

Elimination of large tumors in mice by mRNA-encoded bispecific antibodies

scientific article published on 12 June 2017

Endocytosis of urokinase-plasminogen activator inhibitor type 1 complexes bound to a chimeric transmembrane urokinase receptor

scientific article published on March 1994

Erratum: Elimination of large tumors in mice by mRNA-encoded bispecific antibodies

scientific article published in October 2017

Exogenous siRNA mediates sequence-independent gene suppression by signaling through toll-like receptor 3.

scientific article published on January 2004

Expression kinetics of nucleoside-modified mRNA delivered in lipid nanoparticles to mice by various routes

scientific article

Expression of urokinase and its receptor in invasive and non-invasive prostate cancer cell lines

scientific article published on 01 December 1992

Expression of very low density lipoprotein receptor in the vascular wall. Analysis of human tissues by in situ hybridization and immunohistochemistry

scientific article published on June 1996

Extracellular mRNA induces dendritic cell activation by stimulating tumor necrosis factor-alpha secretion and signaling through a nucleotide receptor

scientific article published on 30 January 2002

Generating the optimal mRNA for therapy: HPLC purification eliminates immune activation and improves translation of nucleoside-modified, protein-encoding mRNA ⬇️

scientific article published on September 2, 2011

HIV gag mRNA transfection of dendritic cells (DC) delivers encoded antigen to MHC class I and II molecules, causes DC maturation, and induces a potent human in vitro primary immune response

scientific article published in October 2000

HPLC Purification of In Vitro Transcribed Long RNA ⬇️

scientific article published on January 1, 2013

Heterogeneous nuclear RNA from hairy cell leukemia patients activates 2',5'-oligoadenylate synthetase

scientific article published on September 1, 1991

Identification of Cyclobutane Pyrimidine Dimer-Responsive Genes Using UVB-Irradiated Human Keratinocytes Transfected with In Vitro-Synthesized Photolyase mRNA.

scientific article published on 29 June 2015

Identification of conserved sequences for PCR primer design by multiple alignments of dot matrix plots.

scientific article

In Vitro Transcription of Long RNA Containing Modified Nucleosides ⬇️

scientific article published on January 1, 2013

In vitro-Transcribed mRNA Therapeutics: Out of the Shadows and Into the Spotlight

article published in 2019

In vivo protein expression from mRNA delivered into adult rat brain

scientific article published in January 2001

Incorporation of pseudouridine into mRNA enhances translation by diminishing PKR activation

scientific article

Incorporation of pseudouridine into mRNA yields superior nonimmunogenic vector with increased translational capacity and biological stability

scientific article published on 16 September 2008

Increased erythropoiesis in mice injected with submicrogram quantities of pseudouridine-containing mRNA encoding erythropoietin

scientific article

Increased radioresistance of EJras-transformed human osteosarcoma cells and its modulation by lovastatin, an inhibitor of p21ras isoprenylation

scientific article published on January 1993

Induction of tolerance to focal ischemia in rat brain: dissociation between cortical lesioning and spreading depression

scientific article published in October 2004

Inhibition of HIV-1 infection by small interfering RNA-mediated RNA interference

scientific article published on November 2002

Inhibition of toll-like receptor and cytokine signaling--a unifying theme in ischemic tolerance

scientific article

Interaction of single-chain urokinase-type plasminogen activator with human endothelial cells.

scientific article published in February 1990

Invasive neoplastic uroepithelial cells express high-levels of urokinase receptor and plasminogen receptor, alpha-enolase

scientific article published on 01 December 1993

Lipid nanoparticles enhance the efficacy of mRNA and protein subunit vaccines by inducing robust T follicular helper cell and humoral responses

scientific article published on 04 November 2021

Lipofectin-aided cell delivery of ribozyme targeted to human urokinase receptor mRNA

scientific article published on 01 September 1994

Liposome mediated DNA-transfer into mammalian cells

scientific article published on 01 January 1985

Local delivery of mRNA-encoded cytokines promotes antitumor immunity and tumor eradication across multiple preclinical tumor models

scientific article published in 2021

Measuring Hematocrit in Mice Injected with In Vitro-Transcribed Erythropoietin mRNA

article

Modified uridines are the key to a successful message

scientific article published on 27 September 2021

Native atherosclerosis and vein graft arterialization: association with increased urokinase receptor expression in vitro and in vivo

scientific article published on 01 July 1998

Naturally occurring nucleoside modifications suppress the immunostimulatory activity of RNA: implication for therapeutic RNA development.

scientific article published on September 2007

Neutrophil depletion diminishes monocyte infiltration and improves functional outcome after experimental intracerebral hemorrhage

scientific article published on January 2011

Nucleofection induces transient eIF2α phosphorylation by GCN2 and PERK ⬇️

scientific article published on February 2, 2012

Nucleoside modifications in RNA limit activation of 2'-5'-oligoadenylate synthetase and increase resistance to cleavage by RNase L ⬇️

scientific article published on August 3, 2011

Nucleoside-modified mRNA immunization elicits influenza virus hemagglutinin stalk-specific antibodies

scientific article published in Nature Communications

Nucleoside-modified mRNA vaccines induce potent T follicular helper and germinal center B cell responses.

scientific article

Overexpression of urokinase receptor in mammalian cells following administration of the in vitro transcribed encoding mRNA.

scientific article published in June 1999

Overexpression of urokinase receptor increases matrix invasion without altering cell migration in a human osteosarcoma cell line

scientific article published on July 1993

Oxidative damage of SP-D abolishes control of eosinophil extracellular DNA trap formation

scientific article published on 7 May 2018

Phosphate-enhanced transfection of cationic lipid-complexed mRNA and plasmid DNA ⬇️

scientific article published on March 2, 1998

Phosphorothioate analogues of 2',5'-oligoadenylate. Activation of 2',5'-oligoadenylate-dependent endoribonuclease by 2',5'-phosphorothioate cores and 5'-monophosphates

scientific article

Phosphorothioate analogues of 2',5'-oligoadenylate. Enzymatic synthesis, properties, and biological activities of 2',5'-phosphorothioates from adenosine 5'-O-(2-thiotriphosphate) and adenosine 5'-O-(3-thiotriphosphate).

scientific article published in November 1987

Phosphorothioate analogues of 2',5'-oligoadenylate. Enzymatically synthesized 2',5'-phosphorothioate dimer and trimer: unequivocal structural assignment and activation of 2',5'-oligoadenylate-dependent endoribonuclease

scientific article

Platelet factor 4 binds to low-density lipoprotein receptors and disrupts the endocytic machinery, resulting in retention of low-density lipoprotein on the cell surface

scientific article published in May 2002

Positive and negative elements mediate control of alternative splicing in the AMPD1 gene

scientific article published on April 2000

Preconditioning with cortical spreading depression does not upregulate Cu/Zn-SOD or Mn-SOD in the cerebral cortex of rats ⬇️

scientific article published on November 30, 2001

Publisher Correction: COVID-19 vaccine BNT162b1 elicits human antibody and TH1 T cell responses

correction of a scholarly article

Purification of mRNA Encoding Chimeric Antigen Receptor Is Critical for Generation of a Robust T-Cell Response

scientific article published on 02 October 2018

RNase L and increased endoribonuclease activities in the mononuclear cells of patients with chronic myelogenous leukemia

scientific article published on 01 March 1994

Rapid method for screening and cloning cDNAs generated in differential mRNA display: application of northern blot for affinity capturing of cDNAs

scientific article published on May 1994

Regulation of the endothelial cell urokinase-type plasminogen activator receptor. Evidence for cyclic AMP-dependent and protein kinase C-dependent pathways ⬇️

scientific article published on 01 February 1993

Sequence analysis of the 5.34-kb 5' flanking region of the human rhodopsin-encoding gene

scientific article published in December 1995

Sequence- and target-independent angiogenesis suppression by siRNA via TLR3

scientific article

Small interfering RNAs mediate sequence-independent gene suppression and induce immune activation by signaling through toll-like receptor 3.

scientific article published in June 2004

Stimulatory effect of unsaturated fatty acids on the level of plasminogen activator inhibitor-1 mRNA in cultured human endothelial cells

scientific article published on 01 March 1995

Suppression of RNA recognition by Toll-like receptors: the impact of nucleoside modification and the evolutionary origin of RNA

scientific article

The Emerging Role of In Vitro-Transcribed mRNA in Adoptive T Cell Immunotherapy

scientific article published on 02 February 2019

The expression of urokinase-related genes in superficial and invasive transitional cell carcinoma ⬇️

scientific article published on 01 January 1998

Thermal preconditioning before rat arterial balloon injury: limitation of injury and sustained reduction of intimal thickening

scientific article published on 01 January 1998

Toll-like receptor 4 contributes to poor outcome after intracerebral hemorrhage

scientific article published on October 2011

Transfection of Human Keratinocytes with Nucleoside-Modified mRNA Encoding CPD-Photolyase to Repair DNA Damage

scientific article

Transfection of pseudouridine-modified mRNA encoding CPD-photolyase leads to repair of DNA damage in human keratinocytes: a new approach with future therapeutic potential

scientific article published on 11 October 2013

Zika virus protection by a single low-dose nucleoside-modified mRNA vaccination

scientific article

gp340 expressed on human genital epithelia binds HIV-1 envelope protein and facilitates viral transmission

scientific article published in September 2007

mRNA is an endogenous ligand for Toll-like receptor 3.

scientific article

mRNA-based therapeutics--developing a new class of drugs

scientific article

mRNA: Fulfilling the Promise of Gene Therapy

scientific article published on September 2015

n-Decyl-NHpppA2'p5'A2'p5'A A phosphatase-resistant, active pppA2'p5'A2'p5'A analog.

scientific article

Paulina is supported by:

About Paulina

Help