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List of works by Richard M Scearce

A group M consensus envelope glycoprotein induces antibodies that neutralize subsets of subtype B and C HIV-1 primary viruses

scientific article published on September 2006

Amino Acid Changes in the HIV-1 gp41 Membrane Proximal Region Control Virus Neutralization Sensitivity

scientific article published on 31 August 2016

Analysis of HIV-1 subtype B third variable region peptide motifs for induction of neutralizing antibodies against HIV-1 primary isolates

scientific article published on 20 October 2005

Anti-Ebola MAb 17A3 reacts with bovine and human alpha-2-macroglobulin proteins

scientific article published on 4 May 2010

Anti-phospholipid human monoclonal antibodies inhibit CCR5-tropic HIV-1 and induce beta-chemokines

scientific article

Antibody light-chain-restricted recognition of the site of immune pressure in the RV144 HIV-1 vaccine trial is phylogenetically conserved

scientific article

Antigenicity and immunogenicity of a synthetic human immunodeficiency virus type 1 group m consensus envelope glycoprotein

scientific article published on January 2005

Antigenicity and immunogenicity of transmitted/founder, consensus, and chronic envelope glycoproteins of human immunodeficiency virus type 1

scientific article published on 30 January 2013

Cardiolipin polyspecific autoreactivity in two broadly neutralizing HIV-1 antibodies.

scientific article

Co-evolution of a broadly neutralizing HIV-1 antibody and founder virus

scientific article

Comparison of Immunogenicity in Rhesus Macaques of Transmitted-Founder, HIV-1 Group M Consensus, and Trivalent Mosaic Envelope Vaccines Formulated as a DNA Prime, NYVAC, and Envelope Protein Boost

scientific article published on 8 April 2015

Cross-reactive monoclonal antibodies to multiple HIV-1 subtype and SIVcpz envelope glycoproteins

scientific article published on 09 September 2009

Crystal structure of a non-neutralizing antibody to the HIV-1 gp41 membrane-proximal external region ⬇️

scientific article published on November 14, 2010

Detection of Ebola virus envelope using monoclonal and polyclonal antibodies in ELISA, surface plasmon resonance and a quartz crystal microbalance immunosensor.

scientific article

Envelope deglycosylation enhances antigenicity of HIV-1 gp41 epitopes for both broad neutralizing antibodies and their unmutated ancestor antibodies

scientific article

Expression of the CD7 ligand K-12 in human thymic epithelial cells: regulation by IFN-gamma

scientific article published on 01 January 2005

Functional, non-clonal IgMa-restricted B cell receptor interactions with the HIV-1 envelope gp41 membrane proximal external region

scientific article

HIV-1 Consensus Envelope-Induced Broadly Binding Antibodies

scientific article

HIV-1 Envelope Mimicry of Host Enzyme Kynureninase Does Not Disrupt Tryptophan Metabolism.

scientific article published on 14 November 2016

High throughput functional analysis of HIV-1 env genes without cloning

scientific article

Human immunodeficiency virus type 1 gp41 antibodies that mask membrane proximal region epitopes: antibody binding kinetics, induction, and potential for regulation in acute infection

scientific article

Immune checkpoint modulation enhances HIV-1 antibody induction

scientific article published on 19 February 2020

Immunodominance of Antibody Recognition of the HIV Envelope V2 Region in Ig-Humanized Mice

scientific article published on 23 December 2016

Immunogenicity of NYVAC prime-protein boost HIV-1 envelope vaccination and SHIV challenge of nonhuman primates

scientific article published on 7 February 2018

In vitro and in vivo characterization of anthrax anti-protective antigen and anti-lethal factor monoclonal antibodies after passive transfer in a mouse lethal toxin challenge model to define correlates of immunity

scientific article

Increased immunogenicity of HIV envelope subunit complexed with alpha2-macroglobulin when combined with monophosphoryl lipid A and GM-CSF

scientific article published on 01 May 2002

Induction of Antibodies in Rhesus Macaques That Recognize a Fusion-Intermediate Conformation of HIV-1 gp41 ⬇️

scientific article published on November 30, 2011

Induction of HIV-1 broad neutralizing antibodies in 2F5 knock-in mice: selection against membrane proximal external region-associated autoreactivity limits T-dependent responses

scientific article published on 5 August 2013

Initiation of HIV neutralizing B cell lineages with sequential envelope immunizations ⬇️

scientific article published on 23 November 2017

Leukemia inhibitory factor is a mediator of Escherichia coli lipopolysaccharide-induced acute thymic atrophy

scientific article published in November 2002

Lipid nanoparticle encapsulated nucleoside-modified mRNA vaccines elicit polyfunctional HIV-1 antibodies comparable to proteins in nonhuman primates

scientific article published on 31 December 2020

Mimicry of an HIV broadly neutralizing antibody epitope with a synthetic glycopeptide.

scientific article published on March 2017

Mouse and human antibodies bind HLA-E-leader peptide complexes and enhance NK cell cytotoxicity

scientific article published on 28 March 2022

Murine CD7 shares antigenic cross-reactivity with HSP-60.

scientific article

Nonneutralizing HIV-1 gp41 envelope cluster II human monoclonal antibodies show polyreactivity for binding to phospholipids and protein autoantigens

scientific article published on 24 November 2010

Nucleoside-modified mRNA vaccines induce potent T follicular helper and germinal center B cell responses.

scientific article

Structural Constraints of Vaccine-Induced Tier-2 Autologous HIV Neutralizing Antibodies Targeting the Receptor-Binding Site

scientific article

Targeted selection of HIV-specific antibody mutations by engineering B cell maturation

scientific article

The role of antibody polyspecificity and lipid reactivity in binding of broadly neutralizing anti-HIV-1 envelope human monoclonal antibodies 2F5 and 4E10 to glycoprotein 41 membrane proximal envelope epitopes

scientific article

Tissue memory B cell repertoire analysis after ALVAC/AIDSVAX B/E gp120 immunization of rhesus macaques

scientific article published on 08 December 2016

Vaccine Elicitation of High Mannose-Dependent Neutralizing Antibodies against the V3-Glycan Broadly Neutralizing Epitope in Nonhuman Primates

scientific article

Vaccine Induction of Heterologous Tier 2 HIV-1 Neutralizing Antibodies in Animal Models

scientific article published in December 2017

Zika virus protection by a single low-dose nucleoside-modified mRNA vaccination

scientific article

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