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List of works by Joan A Geoghegan

<i>Staphylococcus aureus</i> binds to the N-terminal region of corneodesmosin to adhere to the stratum corneum in atopic dermatitis

scientific article published on 01 January 2021

A horizontally gene transferred copper resistance locus confers hyper-resistance to antibacterial copper toxicity and enables survival of community acquired methicillin resistant Staphylococcus aureus USA300 in macrophages

scientific article published on 9 March 2018

A short sequence within subdomain N1 of region A of the Staphylococcus aureus MSCRAMM clumping factor A is required for export and surface display

scientific article published on 24 January 2014

Adhesion of Staphylococcus aureus to Corneocytes from Atopic Dermatitis Patients Is Controlled by Natural Moisturizing Factor Levels

scientific article published on 14 August 2018

Adhesion, invasion and evasion: the many functions of the surface proteins of Staphylococcus aureus

scientific article published on January 2014

Biofilm formation by staphylococci and streptococci: structural, functional, and regulatory aspects and implications for pathogenesis

scientific article published on 8 April 2015

CRIg Functions as a Macrophage Pattern Recognition Receptor to Directly Bind and Capture Blood-Borne Gram-Positive Bacteria.

scientific article published on 21 June 2016

Cell Wall-Anchored Surface Proteins of Staphylococcus aureus: Many Proteins, Multiple Functions

scientific article published on 15 December 2015

Clumping Factor B Promotes Adherence of Staphylococcus aureus to Corneocytes in Atopic Dermatitis.

scientific article published on 3 April 2017

Clumping factor A interaction with complement factor I increases C3b cleavage on the bacterial surface of Staphylococcus aureus and decreases complement-mediated phagocytosis

scientific article

Clumping factor B is an important virulence factor during Staphylococcus aureus skin infection and a promising vaccine target

scientific article published on 22 April 2019

Complement regulator C4BP binds to Staphylococcus aureus surface proteins SdrE and Bbp inhibiting bacterial opsonization and killing.

scientific article published on 9 November 2013

Conjugate of an IgG Binding Domain with Botulinum Neurotoxin A Lacking the Acceptor Moiety Targets Its SNARE Protease into TrkA-Expressing Cells When Coupled to Anti-TrkA IgG or Fc-βNGF.

scientific article

Direct interaction of iron-regulated surface determinant IsdB of Staphylococcus aureus with the GPIIb/IIIa receptor on platelets

scientific article published on 10 December 2009

Dysregulated skin barrier function in Tmem79 mutant mice promotes IL-17A-dependent spontaneous skin and lung inflammation

scientific article published on 09 July 2020

Editorial overview: Bacterial regulatory hierarchies and networks

scientific article published on 01 June 2020

Emergence of the epidemic methicillin-resistant Staphylococcus aureus strain USA300 coincides with horizontal transfer of the arginine catabolic mobile element and speG-mediated adaptations for survival on skin

scientific article

Fibronectin Binding Proteins SpsD and SpsL Both Support Invasion of Canine Epithelial Cells by Staphylococcus pseudintermedius.

scientific article published on 3 August 2015

Fibronectin binding protein B binds to loricrin and promotes corneocyte adhesion by Staphylococcus aureus

scientific article published on 06 May 2022

Fibronectin-binding protein B (FnBPB) from Staphylococcus aureus protects against the antimicrobial activity of histones

scientific article published on 08 January 2019

Fibronectin-binding proteins are required for biofilm formation by community-associated methicillin-resistant Staphylococcus aureus strain LAC.

scientific article

Force-Induced Strengthening of the Interaction between Staphylococcus aureus Clumping Factor B and Loricrin

scientific article published on 5 December 2017

Forces between Staphylococcus aureus and human skin

scientific article published on 06 May 2016

Forces driving the attachment of Staphylococcus epidermidis to fibrinogen-coated surfaces

scientific article published on 10 October 2013

Functional analysis of a murine monoclonal antibody against the repetitive region of the fibronectin-binding adhesins fibronectin-binding protein A and fibronectin-binding protein B from Staphylococcus aureus

scientific article

Genome sequence of Staphylococcus lugdunensis N920143 allows identification of putative colonization and virulence factors

scientific article published on 4 July 2011

Host-specialized fibrinogen-binding by a bacterial surface protein promotes biofilm formation and innate immune evasion

scientific article published on 19 June 2019

IsdC from Staphylococcus lugdunensis induces biofilm formation under low-iron growth conditions

scientific article

Lessons from the Crystal Structure of the S. aureus Surface Protein Clumping Factor A in Complex With Tefibazumab, an Inhibiting Monoclonal Antibody

scientific article published on October 2016

Live-Cell Nanoscopy in Antiadhesion Therapy.

scientific article

Manipulation of Autophagy in Phagocytes Facilitates Staphylococcus aureus Bloodstream Infection

scientific article published on 22 June 2015

Mechanomicrobiology: How Mechanical Forces Activate Staphylococcus aureus Adhesion

scientific article published on 01 June 2018

Memory Th1 Cells Are Protective in Invasive Staphylococcus aureus Infection.

scientific article published on 5 November 2015

Mobile-Genetic-Element-Encoded Hypertolerance to Copper Protects Staphylococcus aureus from Killing by Host Phagocytes ⬇️

scientific article published on 16 October 2018

Molecular Characterization of the Multiple Interactions of SpsD, a Surface Protein from Staphylococcus pseudintermedius, with Host Extracellular Matrix Proteins

scientific article

Molecular Interactions of Human Plasminogen with Fibronectin-binding Protein B (FnBPB), a Fibrinogen/Fibronectin-binding Protein from Staphylococcus aureus.

scientific article published on 7 July 2016

Molecular characterization of the interaction of staphylococcal microbial surface components recognizing adhesive matrix molecules (MSCRAMM) ClfA and Fbl with fibrinogen.

scientific article

Molecular interactions and inhibition of the staphylococcal biofilm-forming protein SdrC

scientific article

Nasal colonisation by Staphylococcus aureus depends upon clumping factor B binding to the squamous epithelial cell envelope protein loricrin

scientific article

Nlrp-3-driven interleukin 17 production by γδT cells controls infection outcomes during Staphylococcus aureus surgical site infection.

scientific article published on 30 September 2013

Protein A is released into the Staphylococcus aureus culture supernatant with an unprocessed sorting signal

scientific article

Protein-based biofilm matrices in Staphylococci

scientific article published on 10 December 2014

Role for the A domain of unprocessed accumulation-associated protein (Aap) in the attachment phase of the Staphylococcus epidermidis biofilm phenotype

scientific article

Role of surface protein SasG in biofilm formation by Staphylococcus aureus.

scientific article published on 3 September 2010

Socializing, networking and development: a report from the second 'Young Microbiologists Symposium on Microbe Signalling, Organization and Pathogenesis'.

scientific article published on 18 September 2012

Staphylococcal biofilm-forming protein has a contiguous rod-like structure

scientific article

Staphylococcus aureus Fibronectin-Binding Protein A Mediates Cell-Cell Adhesion through Low-Affinity Homophilic Bonds

scientific article published on 26 May 2015

Staphylococcus aureus and Atopic Dermatitis: A Complex and Evolving Relationship.

scientific article published on 9 December 2017

Staphylococcus aureus clumping factor A is a force-sensitive molecular switch that activates bacterial adhesion.

scientific article

Staphylococcus aureus surface protein SdrE binds complement regulator factor H as an immune evasion tactic

scientific article (publication date: 2012)

Staphylococcus pseudintermedius expresses surface proteins that closely resemble those from Staphylococcus aureus

scientific article

Staphylokinase Control of Staphylococcus aureus Biofilm Formation and Detachment Through Host Plasminogen Activation

scientific article published on July 2015

Structures of lipoprotein signal peptidase II from Staphylococcus aureus complexed with antibiotics globomycin and myxovirescin

scientific article published on 09 January 2020

Subdomains N2N3 of fibronectin binding protein A mediate Staphylococcus aureus biofilm formation and adherence to fibrinogen using distinct mechanisms.

scientific article published on 5 April 2013

Targeted nasal vaccination provides antibody-independent protection against Staphylococcus aureus

scientific article published on 22 November 2013

The Role of Staphylococcus aureus Virulence Factors in Skin Infection and Their Potential as Vaccine Antigens

scientific article

The Staphylococcus aureus cell wall-anchored protein clumping factor A is an important T cell antigen.

scientific article published on 25 September 2017

The binding force of the staphylococcal adhesin SdrG is remarkably strong

scientific article published on 20 June 2014

The immune evasion protein Sbi of Staphylococcus aureus occurs both extracellularly and anchored to the cell envelope by binding lipoteichoic acid ⬇️

scientific article

Zinc-dependent mechanical properties of Staphylococcus aureus biofilm-forming surface protein SasG.

scientific article

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