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List of works by Eric Nuermberger

<i>In Vitro</i> Activity of Bedaquiline and Imipenem against Actively Growing, Nutrient-Starved, and Intracellular Mycobacterium abscessus

scientific article published on 13 September 2021

A Combination Regimen Design Program Based on Pharmacodynamic Target Setting for Childhood Tuberculosis: Design Rules for the Playground

scientific article

A Faropenem, Linezolid, and Moxifloxacin Regimen for Both Drug-Susceptible and Multidrug-Resistant Tuberculosis in Children: FLAME Path on the Milky Way.

scientific article

A multi-antigenic MVA vaccine increases efficacy of combination chemotherapy against Mycobacterium tuberculosis

scientific article published on 2 May 2018

A novel inhibitor of gyrase B is a potent drug candidate for treatment of tuberculosis and nontuberculosis mycobacterial infections.

scientific article

Accelerated detection of Mycobacterium tuberculosis genes essential for bacterial survival in guinea pigs, compared with mice

scientific article published on 23 April 2007

Accelerated detection of mycolactone production and response to antibiotic treatment in a mouse model of Mycobacterium ulcerans disease

scientific article (publication date: 2014)

Activities of Rifampin, Rifapentine and Clarithromycin Alone and in Combination against Mycobacterium ulcerans Disease in Mice ⬇️

scientific article published on January 4, 2011

Activity of 5-chloro-pyrazinamide in mice infected with Mycobacterium tuberculosis or Mycobacterium bovis ⬇️

scientific article published on November 1, 2012

Activity of a Long-Acting Injectable Bedaquiline Formulation in a Paucibacillary Mouse Model of Latent Tuberculosis Infection

scientific article published on 27 March 2019

Activity of a long-acting injectable bedaquiline formulation in a paucibacillary mouse model of latent tuberculosis infection

Activity of the Fluoroquinolone DC-159a in the Initial and Continuation Phases of Treatment of Murine Tuberculosis ⬇️

scientific article published on January 31, 2011

Addition of PNU-100480 to first-line drugs shortens the time needed to cure murine tuberculosis.

scientific article

Advancing Translational Science for Pulmonary NTM Infections: A Roadmap for Research

scientific article published on 01 April 2019

Advancing the Therapeutic Potential of Indoleamides for Tuberculosis

scientific article published on 24 June 2019

Antibiotic resistance in Streptococcus pneumoniae: what does the future hold?

scientific article published on May 2004

Antibiotics. Targeting DnaN for tuberculosis therapy using novel griselimycins

scientific article

Assessing the landscape of tools and approaches for novel tuberculosis regimen development

scientific article published on 01 June 2015

Assessment of Clofazimine and TB47 Combination Activity against Mycobacterium abscessus Using a Bioluminescent Approach

scientific article published on 21 February 2020

Autoluminescent Mycobacterium tuberculosis for rapid, real-time, non-invasive assessment of drug and vaccine efficacy ⬇️

scientific article

BCG-Mediated Protection against Mycobacterium ulcerans Infection in the Mouse ⬇️

scientific article published on March 15, 2011

Bactericidal activity does not predict sterilizing activity: the case of rifapentine in the murine model of Mycobacterium ulcerans disease

scientific article

Bactericidal activity of increasing daily and weekly doses of moxifloxacin in murine tuberculosis

scientific article

Bactericidal and Sterilizing Activity of a Novel Regimen with Bedaquiline, Pretomanid, Moxifloxacin, and Pyrazinamide in a Murine Model of Tuberculosis

scientific article published on 19 June 2017

Bedaquiline and Pyrazinamide Treatment Responses Are Affected by Pulmonary Lesion Heterogeneity in Mycobacterium tuberculosis Infected C3HeB/FeJ Mice

scientific article published on 24 February 2016

Biphasic kill curve of isoniazid reveals the presence of drug-tolerant, not drug-resistant, Mycobacterium tuberculosis in the guinea pig.

scientific article

Combination chemotherapy with the nitroimidazopyran PA-824 and first-line drugs in a murine model of tuberculosis

scientific article

Community-acquired meticillin-resistant Staphylococcus aureus: an emerging threat

scientific article

Comparative Efficacy of Rifapentine Alone and in Combination with Isoniazid for Latent Tuberculosis Infection: a Translational Pharmacokinetic-Pharmacodynamic Modeling Study

scientific article published on 04 October 2021

Comparative Efficacy of the Novel Diarylquinoline TBAJ-876 and Bedaquiline against a Resistant <i>Rv0678</i> Mutant in a Mouse Model of Tuberculosis

scientific article published on 27 September 2021

Comparison of the 'Denver regimen' against acute tuberculosis in the mouse and guinea pig.

scientific article

Comprehensive analysis of methods used for the evaluation of compounds against Mycobacterium tuberculosis

scientific article published on 30 August 2012

Concentration-Dependent Synergy and Antagonism of Linezolid and Moxifloxacin in the Treatment of Childhood Tuberculosis: The Dynamic Duo.

scientific article

Confronting Multidrug-Resistant Tuberculosis ⬇️

scientific article published on June 7, 2012

Contribution of Moxifloxacin or Levofloxacin in Second-Line Regimens with or without Continuation of Pyrazinamide in Murine Tuberculosis ⬇️

scientific article published on July 1, 2013

Contribution of Oxazolidinones to the Efficacy of Novel Regimens Containing Bedaquiline and Pretomanid in a Mouse Model of Tuberculosis

scientific article

Contribution of Pretomanid to Novel Regimens Containing Bedaquiline with either Linezolid or Moxifloxacin and Pyrazinamide in Murine Models of Tuberculosis

scientific article published on 25 April 2019

Contribution of pretomanid to novel regimens containing bedaquiline with either linezolid or moxifloxacin and pyrazinamide in murine models of tuberculosis

scholarly article published 8 January 2019

Contribution of the nitroimidazoles PA-824 and TBA-354 to the activity of novel regimens in murine models of tuberculosis

scientific article

Correction for lanoix et Al., novel regimens identified in mice for treatment of latent tuberculosis infection in contacts of patients with multidrug-resistant tuberculosis

scientific article published in March 2015

Correlations Between the Hollow Fiber Model of Tuberculosis and Therapeutic Events in Tuberculosis Patients: Learn and Confirm

scientific article published on August 2015

Current development and future prospects in chemotherapy of tuberculosis

scientific article published on 4 June 2010

Daily dosing of rifapentine cures tuberculosis in three months or less in the murine model

scientific article

Daily rifapentine for treatment of pulmonary tuberculosis. A randomized, dose-ranging trial.

scientific article

Development of New Tuberculosis Drugs: Translation to Regimen Composition for Drug-Sensitive and Multidrug-Resistant Tuberculosis

scientific article published on 17 August 2020

Development of a penem antibiotic against Mycobacteroides abscessus

scientific article published on 07 December 2020

Differential in vitro activity of individual drugs and bedaquiline-rifabutin combinations against actively multiplying and nutrient-starved Mycobacterium abscessus

scientific article published on 09 November 2020

Dormancy phenotype displayed by extracellular Mycobacterium tuberculosis within artificial granulomas in mice

scientific article

Dose-dependent activity of pyrazinamide in animal models of intracellular and extracellular tuberculosis infections.

scientific article

Dose-ranging comparison of rifampin and rifapentine in two pathologically distinct murine models of tuberculosis

scientific article

Drug Concentration Thresholds Predictive of Therapy Failure and Death in Children With Tuberculosis: Bread Crumb Trails in Random Forests

scientific article

Drug Efficacy Testing in the Mouse Footpad Model of Buruli Ulcer

scientific article published on 01 January 2022

Drug resistance mechanisms and novel drug targets for tuberculosis therapy

scientific article published on 11 October 2016

Early Bactericidal Activity of Different Isoniazid Doses for Drug Resistant TB (INHindsight): A Randomized Open-label Clinical Trial

scientific article published on 16 January 2020

Effectiveness of tuberculosis chemotherapy correlates with resistance to Mycobacterium tuberculosis infection in animal models ⬇️

scientific article published on May 20, 2011

Efficacy of Rifampin Plus Clofazimine in a Murine Model of Mycobacterium ulcerans Disease

scientific article

Enhanced bactericidal activity of rifampin and/or pyrazinamide when combined with PA-824 in a murine model of tuberculosis

scientific article published on 11 August 2008

Evaluation of moxifloxacin-containing regimens in pathologically distinct murine tuberculosis models

scientific article

Evaluation of new antituberculosis drugs in mouse models

scientific article published on January 2007

Forecasting Accuracy of the Hollow Fiber Model of Tuberculosis for Clinical Therapeutic Outcomes

scientific article

GSK2556286 Is a Novel Antitubercular Drug Candidate Effective <i>In Vivo</i> with the Potential To Shorten Tuberculosis Treatment

scientific article published on 24 May 2022

Heterogeneous disease progression and treatment response in a C3HeB/FeJ mouse model of tuberculosis

scientific article published on 30 March 2015

High Systemic Exposure of Pyrazinoic Acid Has Limited Antituberculosis Activity in Murine and Rabbit Models of Tuberculosis

scientific article published on 02 May 2016

High-Dose Rifamycins Enable Shorter Oral Treatment in a Murine Model of Mycobacterium ulcerans Disease

scientific article published on 29 January 2019

Host-Mediated Bioactivation of Pyrazinamide: Implications for Efficacy, Resistance, and Therapeutic Alternatives

scientific article published on May 2015

Immunodeficiency and Intermittent Dosing Promote Acquired Rifamycin Monoresistance in Murine Tuberculosis.

scientific article

Impact of Clofazimine Dosing on Treatment-Shortening of the First-Line Regimen in a Mouse Model of Tuberculosis.

scientific article published on 7 May 2018

In Vitro Activity of New Tetracycline Analogs Omadacycline and Eravacycline against Drug-Resistant Clinical Isolates of Mycobacterium abscessus

scientific article published on 24 May 2019

In Vitro Activity of the New β-Lactamase Inhibitors Relebactam and Vaborbactam in Combination with β-Lactams against Mycobacterium abscessus Complex Clinical Isolates

scientific article published on 26 February 2019

In Vitro Assessment of Drug Activity Against Mycobacterium ulcerans

scientific article published on 01 January 2022

In Vivo-Selected Pyrazinoic Acid-Resistant Mycobacterium tuberculosis Strains Harbor Missense Mutations in the Aspartate Decarboxylase PanD and the Unfoldase ClpC1.

scientific article

In vitro and in vivo activity of biapenem against drug-susceptible and rifampicin-resistant Mycobacterium tuberculosis

scientific article published on June 2017

In vivo validation of the mutant selection window hypothesis with moxifloxacin in a murine model of tuberculosis

scientific article

Isoniazid or moxifloxacin in rifapentine-based regimens for experimental tuberculosis?

scientific article published on 21 August 2008

Latent tuberculosis infection

scientific article published on June 2004

Limited activity of clofazimine as a single drug in a mouse model of tuberculosis exhibiting caseous necrotic granulomas

scientific article

Linezolid for Infants and Toddlers With Disseminated Tuberculosis: First Steps

scientific article

Low-dose aerosol model of pneumococcal pneumonia in the mouse: utility for evaluation of antimicrobial efficacy.

scientific article

Mechanistic Modeling of Mycobacterium tuberculosis Infection in Murine Models for Drug and Vaccine Efficacy Studies

scientific article published on 21 February 2020

Model-Based Meta-Analysis of Relapsing Mouse Model Studies from the Critical Path to Tuberculosis Drug Regimens Initiative Database

scientific article published on 31 January 2022

Mouse model of necrotic tuberculosis granulomas develops hypoxic lesions

scientific article published on 23 December 2011

Moxifloxacin-containing Regimen Greatly Reduces Time to Culture Conversion in Murine Tuberculosis ⬇️

scientific article published on October 24, 2003

Moxifloxacin-containing regimens of reduced duration produce a stable cure in murine tuberculosis

scientific article

Multiparameter Responses to Tedizolid Monotherapy and Moxifloxacin Combination Therapy Models of Children With Intracellular Tuberculosis

article

Mutations in fbiD (Rv2983) as a novel determinant of resistance to pretomanid and delamanid in Mycobacterium tuberculosis

scientific article published on 19 October 2020

Mutations in pepQ Confer Low-Level Resistance to Bedaquiline and Clofazimine in Mycobacterium tuberculosis

scientific article published on 16 May 2016

New β-Lactamase Inhibitors Nacubactam and Zidebactam Improve the In Vitro Activity of β-Lactam Antibiotics against Mycobacterium abscessus Complex Clinical Isolates

scientific article published on 23 August 2019

Nonclinical models for antituberculosis drug development: a landscape analysis

scientific article published on June 2015

Noninvasive pulmonary [18F]-2-fluoro-deoxy-D-glucose positron emission tomography correlates with bactericidal activity of tuberculosis drug treatment

scientific article published on 08 September 2009

Novel regimens identified in mice for treatment of latent tuberculosis infection in contacts of patients with multidrug-resistant tuberculosis

scientific article

One Month of Rifapentine plus Isoniazid to Prevent HIV-Related Tuberculosis

article

Optimal Clinical Doses of Faropenem, Linezolid, and Moxifloxacin in Children With Disseminated Tuberculosis: Goldilocks

scientific article

Oxazolidinones Can Replace Clarithromycin in Combination with Rifampin in a Mouse Model of Buruli Ulcer

scientific article published on 26 February 2019

PA-824 Exhibits Time-Dependent Activity in a Murine Model of Tuberculosis ⬇️

scientific article published on October 11, 2010

Paradoxical effect of isoniazid on the activity of rifampin-pyrazinamide combination in a mouse model of tuberculosis

scientific article published on 20 July 2009

Pharmacodynamic Correlates of Linezolid Activity and Toxicity in Murine Models of Tuberculosis

scientific article published on 29 January 2020

Pipeline of drugs for related diseases: tuberculosis

scientific article (publication date: November 2013)

Population pharmacokinetics of rifapentine and desacetyl rifapentine in healthy volunteers: nonlinearities in clearance and bioavailability

scientific article

Potent rifamycin-sparing regimen cures guinea pig tuberculosis as rapidly as the standard regimen

scientific article published on 03 June 2013

Potent twice-weekly rifapentine-containing regimens in murine tuberculosis

scientific article published on 30 March 2006

Powerful bactericidal and sterilizing activity of a regimen containing PA-824, moxifloxacin, and pyrazinamide in a murine model of tuberculosis

scientific article published on 19 February 2008

Predicting nitroimidazole antibiotic resistance mutations in Mycobacterium tuberculosis with protein engineering

scientific article published on 07 February 2020

Presence of multiple lesion types with vastly different microenvironments in C3HeB/FeJ mice following aerosol infection with Mycobacterium tuberculosis.

scientific article published on 30 March 2015

Preserved efficacy and reduced toxicity with intermittent linezolid dosing in combination with bedaquiline and pretomanid in a murine TB model

scientific article published on 20 July 2020

Primary Clofazimine and Bedaquiline Resistance among Isolates from Patients with Multidrug-Resistant Tuberculosis

scientific article published on 20 March 2017

Principles for designing future regimens for multidrug-resistant tuberculosis.

scientific article published on 25 October 2013

Priority-Setting for Novel Drug Regimens to Treat Tuberculosis: An Epidemiologic Model

scientific article

Promising clinical efficacy of streptomycin-rifampin combination for treatment of buruli ulcer (Mycobacterium ulcerans disease)

scientific article

Pyrazinoic Acid Inhibits a Bifunctional Enzyme in Mycobacterium tuberculosis.

scientific article published on 24 April 2017

Rapid assessment of antibacterial activity against Mycobacterium ulcerans by using recombinant luminescent strains

scientific article

Rapid, serial, non-invasive assessment of drug efficacy in mice with autoluminescent Mycobacterium ulcerans infection

scientific article (publication date: 2013)

Repeated administration of high-dose intermittent rifapentine reduces rifapentine and moxifloxacin plasma concentrations

scientific article published on 02 September 2008

Reply to “Contradictory Results with High-Dosage Rifamycin in Mice and Humans” ⬇️

scientific article published on February 1, 2013

Reply to: High-dose First-line Treatment Regimen for Recurrent Rifampicin-susceptible Tuberculosis

scientific article published on 04 March 2020

Rifapentine is not more active than rifampin against chronic tuberculosis in guinea pigs

scientific article

Rifapentine, moxifloxacin, or DNA vaccine improves treatment of latent tuberculosis in a mouse model

scientific article published on 8 September 2005

Role of the dosR-dosS two-component regulatory system in Mycobacterium tuberculosis virulence in three animal models.

scientific article published on 22 December 2008

Selective Inactivity of Pyrazinamide against Tuberculosis in C3HeB/FeJ Mice Is Best Explained by Neutral pH of Caseum

scientific article published on 16 November 2015

Severe community-onset pneumonia in healthy adults caused by methicillin-resistant Staphylococcus aureus carrying the Panton-Valentine leukocidin genes

scientific article published on 7 December 2004

Short-Course Chemotherapy with TMC207 and Rifapentine in a Murine Model of Latent Tuberculosis Infection ⬇️

scientific article published on June 9, 2011

Short-course therapy with daily rifapentine in a murine model of latent tuberculosis infection

scientific article published on 03 September 2009

Shortening Buruli Ulcer Treatment with Combination Therapy Targeting the Respiratory Chain and Exploiting Mycobacterium ulcerans Gene Decay

scientific article published on 24 June 2019

Shortening Tuberculosis Treatment With Fluoroquinolones: Lost in Translation?

scientific article published on November 2015

Shorter-course treatment for Mycobacterium ulcerans disease with high-dose rifamycins and clofazimine in a mouse model of Buruli ulcer

scientific article published on 13 August 2018

Significance of macrolide resistance in Streptococcus pneumoniae

scientific article

Small Animal Models for Human Immunodeficiency Virus (HIV), Hepatitis B, and Tuberculosis: Proceedings of an NIAID Workshop

scientific article published on 01 January 2020

Sterilizing Activities of Novel Combinations Lacking First- and Second-Line Drugs in a Murine Model of Tuberculosis ⬇️

scientific article published on April 2, 2012

Sterilizing Activity of Novel TMC207- and PA-824-Containing Regimens in a Murine Model of Tuberculosis ⬇️

scientific article published on September 19, 2011

Sterilizing Activity of Pyrazinamide in Combination with First-Line Drugs in a C3HeB/FeJ Mouse Model of Tuberculosis.

scientific article published on 7 December 2015

Substitution of moxifloxacin for isoniazid during intensive phase treatment of pulmonary tuberculosis.

scientific article published on 30 April 2009

Substitution of rifapentine for rifampin during intensive phase treatment of pulmonary tuberculosis: study 29 of the tuberculosis trials consortium

scientific article published on 30 July 2012

Systematic Analysis of Hollow Fiber Model of Tuberculosis Experiments

scientific article published on August 2015

Telacebec for ultra-short treatment of Buruli ulcer in a mouse model

scientific article published on 23 March 2020

The Sterilizing Effect of Intermittent Tedizolid for Pulmonary Tuberculosis

scholarly article by Shashikant Srivastava et al published 28 November 2018 in Clinical Infectious Diseases

The clinical significance of macrolide-resistant Streptococcus pneumoniae: it's all relative

scientific article published on 8 December 2003

The epidemiology, pathogenesis, transmission, diagnosis, and management of multidrug-resistant, extensively drug-resistant, and incurable tuberculosis

scientific article

The impact of mouse passaging of Mycobacterium tuberculosis strains prior to virulence testing in the mouse and guinea pig aerosol models

scientific article

The potent bactericidal activity of streptomycin in the guinea pig model of tuberculosis ceases due to the presence of persisters ⬇️

scientific article published on August 6, 2010

Toward an Evidence-Based Nonclinical Road Map for Evaluating the Efficacy of New Tuberculosis (TB) Drug Regimens: Proceedings of a Critical Path to TB Drug Regimens-National Institute of Allergy and Infectious Diseases In Vivo Pharmacology Workshop

scientific article published on 11 January 2016

Treating Mycobacterium ulcerans disease (Buruli ulcer): from surgery to antibiotics, is the pill mightier than the knife? ⬇️

scientific article published on October 1, 2011

Treatment of Tuberculosis with Rifamycin-containing Regimens in Immune-deficient Mice ⬇️

scientific article published on February 17, 2011

Treatment-Shortening Effect of a Novel Regimen Combining Clofazimine and High-Dose Rifapentine in Pathologically Distinct Mouse Models of Tuberculosis

scientific article published on 24 May 2019

Using Bioluminescence To Monitor Treatment Response in Real Time in Mice with Mycobacterium ulcerans Infection ⬇️

scientific article published on November 15, 2010

Verapamil Increases the Bioavailability and Efficacy of Bedaquiline but Not Clofazimine in a Murine Model of Tuberculosis

scientific article published on 16 October 2017

Weekly moxifloxacin and rifapentine is more active than the denver regimen in murine tuberculosis

scientific article published on September 2005

World Health Organization Group 5 Drugs for the Treatment of Drug-Resistant Tuberculosis: Unclear Efficacy or Untapped Potential? ⬇️

scientific article published on July 17, 2012

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