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List of works by Erle S Robertson

A cyclin-binding motif within the amino-terminal homology domain of EBNA3C binds cyclin A and modulates cyclin A-dependent kinase activity in Epstein-Barr virus-infected cells

scientific article published on December 2004

A peptide-based inhibitor for prevention of B cell hyperproliferation induced by Epstein-Barr virus

scientific article published on 31 July 2006

A potential alpha-helix motif in the amino terminus of LANA encoded by Kaposi's sarcoma-associated herpesvirus is critical for nuclear accumulation of HIF-1alpha in normoxia

scientific article

A unique SUMO-2-interacting motif within LANA is essential for KSHV latency

scientific article (publication date: 2013)

Activation of mTORC1 signaling pathway in AIDS-related lymphomas

scientific article published on 16 July 2009

Activation of mammalian target of rapamycin in transformed B lymphocytes is nutrient dependent but independent of Akt, mitogen-activated protein kinase/extracellular signal-regulated kinase kinase, insulin growth factor-I, and serum.

scientific article published on September 2005

An EBV recombinant deleted for residues 130-159 in EBNA3C can deregulate p53/Mdm2 and Cyclin D1/CDK6 which results in apoptosis and reduced cell proliferation

scientific article published on 19 February 2016

An autonomous replicating element within the KSHV genome

scientific article published on August 2007

An essential EBV latent antigen 3C binds Bcl6 for targeted degradation and cell proliferation.

scientific article

Bromodomain-Containing Protein BRD4 Is Hyperphosphorylated in Mitosis

scientific article published on 20 June 2020

Bub1 and CENP-F can contribute to Kaposi's sarcoma-associated herpesvirus genome persistence by targeting LANA to kinetochores

scientific article published on 21 July 2010

Bub1 in Complex with LANA Recruits PCNA To Regulate Kaposi's Sarcoma-Associated Herpesvirus Latent Replication and DNA Translesion Synthesis

scientific article

Building research capacity through programme development and research implementation in resource-limited settings - the Ipabalele study protocol: observational cohort studies determining the effect of HIV on the natural history of cervical cancer in

scientific article published on 30 December 2019

COX-2 induces lytic reactivation of EBV through PGE2 by modulating the EP receptor signaling pathway

scientific article published on 4 June 2015

Carboxyl-terminal amino acids 1052 to 1082 of the latency-associated nuclear antigen (LANA) interact with RBP-Jκ and are responsible for LANA-mediated RTA repression.

scientific article

Cellular corepressor TLE2 inhibits replication-and-transcription- activator-mediated transactivation and lytic reactivation of Kaposi's sarcoma-associated herpesvirus.

scientific article

Cervical Cancer in Botswana: Current State and Future Steps for Screening and Treatment Programs

scientific article

Chromatinization of the KSHV Genome During the KSHV Life Cycle

scientific article

Clinical implications of human papillomavirus infection

scientific article

Collision of Three Pandemics: The Coexistence of Cervical Cancer, HIV Infection, and Prior Tuberculosis in the Sub-Saharan Country of Botswana

scientific article

Comprehensive analysis of LANA interacting proteins essential for viral genome tethering and persistence

scientific article

Conserved cell cycle regulatory properties within the amino terminal domain of the Epstein-Barr virus nuclear antigen 3C.

scientific article published on 20 December 2005

Constitutive Activation of Interleukin-13/STAT6 Contributes to Kaposi's Sarcoma-Associated Herpesvirus-Related Primary Effusion Lymphoma Cell Proliferation and Survival

scientific article

Coordination of KSHV Latent and Lytic Gene Control by CTCF-Cohesin Mediated Chromosome Conformation ⬇️

scientific article published on August 18, 2011

Correction: Shugoshin 1 is dislocated by KSHV-encoded LANA inducing aneuploidy

scholarly article published by Erle S Robertson in 2019

Current Progress in EBV-Associated B-Cell Lymphomas

scientific article

Deregulation of the cell cycle machinery by Epstein-Barr virus nuclear antigen 3C.

scientific article

Detection of Epstein-Barr virus in T-cell prolymphocytic leukemia cells in vitro

scientific article published on 14 September 2008

Dissecting the contribution of EBNA3C domains important for EBV-induced B-cell growth and proliferation

scientific article

Distinct Microbial Signatures Associated With Different Breast Cancer Types.

scientific article published on 15 May 2018

Distinct microbiological signatures associated with triple negative breast cancer

scientific article

Dysregulated cytokine and growth factor expression in OSSN HIV-1 patients from Botswana with multiple infections

scientific article published on 19 April 2012

E2F1 mediated apoptosis induced by the DNA damage response is blocked by EBV nuclear antigen 3C in lymphoblastoid cells.

scientific article

EBNA3C attenuates the function of p53 through interaction with inhibitor of growth family proteins 4 and 5

scientific article

EBNA3C augments Pim-1 mediated phosphorylation and degradation of p21 to promote B-cell proliferation

scientific article

EBNA3C can modulate the activities of the transcription factor Necdin in association with metastasis suppressor protein Nm23-H1.

scientific article

EBNA3C facilitates RASSF1A downregulation through ubiquitin-mediated degradation and promoter hypermethylation to drive B-cell proliferation

scientific article published on 07 January 2019

EBNA3C regulates p53 through induction of Aurora kinase B.

scientific article

EBNA3C-mediated regulation of aurora kinase B contributes to Epstein-Barr virus-induced B-cell proliferation through modulation of the activities of the retinoblastoma protein and apoptotic caspases

scientific article published on 28 August 2013

EBV Nuclear Antigen 3C Mediates Regulation of E2F6 to Inhibit E2F1 Transcription and Promote Cell Proliferation.

scientific article

EBV epitranscriptome reprogramming by METTL14 is critical for viral-associated tumorigenesis.

scientific article published on 21 June 2019

EC5S ubiquitin complex is recruited by KSHV latent antigen LANA for degradation of the VHL and p53 tumor suppressors

scientific article

Early events associated with infection of Epstein-Barr virus infection of primary B-cells

scientific article

Editorial overview: Viruses and cancer

scientific article published on 01 October 2018

Epigenetic Impact on EBV Associated B-Cell Lymphomagenesis

scientific article

Epigenetic Landscape of Kaposi's Sarcoma-Associated Herpesvirus Genome in Classic Kaposi's Sarcoma Tissues

scientific article

Epigenetic Regulation of Tumor Suppressors by Helicobacter pylori Enhances EBV-Induced Proliferation of Gastric Epithelial Cells

scientific article published on 24 April 2018

Epigenetic silencing of tumor suppressor genes during in vitro Epstein-Barr virus infection.

scientific article

Epstein-Barr Virus (EBV): infection, propagation, quantitation, and storage

scientific article published on August 2007

Epstein-Barr Virus Nuclear Antigen 3C Facilitates Cell Proliferation by Regulating Cyclin D2

scholarly article by Yonggang Pei et al published 15 September 2018 in Journal of Virology

Epstein-Barr Virus Nuclear Antigen 3C Putative Repression Domain Mediates Coactivation of the LMP1 Promoter with EBNA-2 ⬇️

scientific article published on January 1, 2002

Epstein-Barr Virus facilitates expression of KLF14 by regulating the cooperative binding of E2F-Rb-HDAC complex in latent infection

scientific article published on 26 August 2020

Epstein-Barr Virus nuclear antigen 1 (EBNA1) confers resistance to apoptosis in EBV-positive B-lymphoma cells through up-regulation of survivin

scientific article published on 19 November 2010

Epstein-Barr Virus: Diseases Linked to Infection and Transformation

scientific article

Epstein-Barr virus detected in a head and neck squamous cell carcinoma cell line derived from an immunocompromised patient.

scientific article published on October 2003

Epstein-Barr virus essential antigen EBNA3C attenuates H2AX expression

scientific article published on 15 January 2014

Epstein-Barr virus latency: current and future perspectives

scientific article published on 07 October 2015

Epstein-Barr virus latent antigen 3C can mediate the degradation of the retinoblastoma protein through an SCF cellular ubiquitin ligase

scientific article

Epstein-Barr virus latent antigens EBNA3C and EBNA1 modulate epithelial to mesenchymal transition of cancer cells associated with tumor metastasis

scientific article published on 13 December 2014

Epstein-Barr virus latent nuclear antigens can induce metastasis in a nude mouse model

scientific article

Epstein-Barr virus nuclear antigen 1 interacts with Nm23-H1 in lymphoblastoid cell lines and inhibits its ability to suppress cell migration

scientific article

Epstein-Barr virus nuclear antigen 3C and prothymosin alpha interact with the p300 transcriptional coactivator at the CH1 and CH3/HAT domains and cooperate in regulation of transcription and histone acetylation.

scientific article

Epstein-Barr virus nuclear antigen 3C augments Mdm2-mediated p53 ubiquitination and degradation by deubiquitinating Mdm2.

scientific article

Epstein-Barr virus nuclear antigen 3C facilitates G1-S transition by stabilizing and enhancing the function of cyclin D1.

scientific article

Epstein-Barr virus nuclear antigen 3C interacts with and enhances the stability of the c-Myc oncoprotein

scientific article

Epstein-Barr virus nuclear antigen 3C recruits histone deacetylase activity and associates with the corepressors mSin3A and NCoR in human B-cell lines

scientific article

Epstein-Barr virus nuclear antigen 3C regulates cyclin A/p27 complexes and enhances cyclin A-dependent kinase activity

scientific article published on February 2004

Epstein-Barr virus nuclear antigen 3C stabilizes Gemin3 to block p53-mediated apoptosis

scientific article

Epstein-Barr virus nuclear antigen 3C targets p53 and modulates its transcriptional and apoptotic activities

scientific article

Epstein-Barr virus protein can upregulate cyclo-oxygenase-2 expression through association with the suppressor of metastasis Nm23-H1

scientific article

Epstein-Barr virus-associated B-cell lymphomas: pathogenesis and clinical outcomes

scientific article published on 03 March 2011

Erratum for Jha et al., "Gammaherpesvirus Infection of Human Neuronal Cells"

scientific article published on 05 January 2021

Erratum for Pandey et al., "Epigenetic Regulation of Tumor Suppressors by Helicobacter pylori Enhances EBV-Induced Proliferation of Gastric Epithelial Cells"

scientific article published on 15 December 2020

Evidence of an oncogenic gammaherpesvirus in domestic dogs ⬇️

scientific article published on March 8, 2012

Expression of alpha V integrin is modulated by Epstein-Barr virus nuclear antigen 3C and the metastasis suppressor Nm23-H1 through interaction with the GATA-1 and Sp1 transcription factors

scientific article published on 2 May 2006

Functional modulation of the metastatic suppressor Nm23-H1 by oncogenic viruses

scientific article

G-quadruplex-interacting compounds alter latent DNA replication and episomal persistence of KSHV.

scientific article published on 2 February 2016

Gammaherpesvirus Infection of Human Neuronal Cells

scientific article

Genetic diversity in L1 ORF of human papillomavirus in women with cervical cancer with and without human immunodeficiency virus in Botswana and Kenya

scientific article published on 27 January 2022

H2AX phosphorylation is important for LANA-mediated Kaposi's sarcoma-associated herpesvirus episome persistence

scientific article published on 28 February 2013

Herpesvirus Epigenetic Reprogramming and Oncogenesis

scientific article published on 01 September 2020

Human Oncogenic Herpesvirus and Post-translational Modifications - Phosphorylation and SUMOylation

scientific article

Hypoxia inactivates the VHL tumor suppressor through PIASy-mediated SUMO modification

scientific article

IL-2- and IL-15-induced activation of the rapamycin-sensitive mTORC1 pathway in malignant CD4+ T lymphocytes.

scientific article

IRF-4-mediated CIITA transcription is blocked by KSHV encoded LANA to inhibit MHC II presentation

scientific article

Identification of a 3-β-homoalanine conjugate of brusatol with reduced toxicity in mice

scientific article published on 21 September 2020

Identification of fungal pathogens in a patient with acute myelogenic leukemia using a pathogen detection array technology

scientific article

Impact of EBV essential nuclear protein EBNA-3C on B-cell proliferation and apoptosis

scientific article published on March 2013

Increased viral load correlates with improved survival in HPV-16-associated tonsil carcinoma patients

scientific article published on 01 May 2008

Induction of Kaposi's sarcoma-associated herpesvirus latency-associated nuclear antigen by the lytic transactivator RTA: a novel mechanism for establishment of latency

scientific article

Inhibition of KAP1 enhances hypoxia-induced Kaposi's sarcoma-associated herpesvirus reactivation through RBP-Jκ.

scientific article

Inhibition of KSHV-infected primary effusion lymphomas in NOD/SCID mice by gamma-secretase inhibitor.

scientific article published on 7 November 2009

Intracellular activated Notch1 is critical for proliferation of Kaposi's sarcoma-associated herpesvirus-associated B-lymphoma cell lines in vitro

scientific article published on July 2006

Intracellular-activated Notch1 can reactivate Kaposi's sarcoma-associated herpesvirus from latency

scientific article published on 15 May 2006

Isolation and characterization of mouse and human esophageal epithelial cells in 3D organotypic culture

scientific article

Isolation of human peripheral blood mononuclear cells (PBMCs)

scientific article published on 01 August 2007

KSHV LANA--the master regulator of KSHV latency

scientific article

KSHV encoded LANA upregulates Pim-1 and is a substrate for its kinase activity

scientific article published on 27 April 2006

KSHV-Mediated Regulation of Par3 and SNAIL Contributes to B-Cell Proliferation

scientific article

KSHV-encoded LANA protects the cellular replication machinery from hypoxia induced degradation ⬇️

scientific article published on 03 September 2019

Kaposi's Sarcoma Herpesvirus Upregulates Aurora A Expression to Promote p53 Phosphorylation and Ubiquitylation ⬇️

scientific article published on January 1, 2012

Kaposi's Sarcoma-Associated Herpesvirus-Encoded Latency-Associated Nuclear Antigen Reduces Interleukin-8 Expression in Endothelial Cells and Impairs Neutrophil Chemotaxis by Degrading Nuclear p65 ⬇️

scientific article published on June 22, 2011

Kaposi's sarcoma herpesvirus-encoded latency-associated nuclear antigen stabilizes intracellular activated Notch by targeting the Sel10 protein

scholarly article

Kaposi's sarcoma-associated herpesvirus RTA activates the processivity factor ORF59 through interaction with RBP-Jkappa and a cis-acting RTA responsive element.

scientific article published on 10 September 2008

Kaposi's sarcoma-associated herpesvirus genome programming during the early stages of primary infection of peripheral blood mononuclear cells.

scientific article

Kaposi's sarcoma-associated herpesvirus inhibits interleukin-4-mediated STAT6 phosphorylation to regulate apoptosis and maintain latency

scientific article published on 18 August 2010

Kaposi's sarcoma-associated herpesvirus latent protein LANA interacts with HIF-1 alpha to upregulate RTA expression during hypoxia: Latency control under low oxygen conditions

scientific article published on August 2006

Kaposi's sarcoma-associated herpesvirus reactivation is regulated by interaction of latency-associated nuclear antigen with recombination signal sequence-binding protein Jkappa, the major downstream effector of the Notch signaling pathway

scientific article

Kaposi's sarcoma-associated herpesvirus-encoded LANA can induce chromosomal instability through targeted degradation of the mitotic checkpoint kinase Bub1

scientific article published on 16 April 2014

Kaposi's sarcoma-associated herpesvirus-encoded LANA can interact with the nuclear mitotic apparatus protein to regulate genome maintenance and segregation

scientific article

Kaposi's sarcoma-associated herpesvirus-encoded LANA contributes to viral latent replication by activating phosphorylation of survivin

scientific article

Kaposi's sarcoma-associated herpesvirus-encoded latency-associated nuclear antigen induces chromosomal instability through inhibition of p53 function

scientific article published on January 2006

Kaposi's sarcoma-associated herpesvirus-encoded latency-associated nuclear antigen inhibits lytic replication by targeting Rta: a potential mechanism for virus-mediated control of latency

scientific article

Kaposi's sarcoma-associated herpesvirus-encoded latency-associated nuclear antigen modulates K1 expression through its cis-acting elements within the terminal repeats

scientific article

LANA oligomeric architecture is essential for KSHV nuclear body formation and viral genome maintenance during latency

scientific article published on 25 January 2019

Lactic Acid Downregulates Viral MicroRNA To Promote Epstein-Barr Virus-Immortalized B Lymphoblastic Cell Adhesion and Growth

scientific article published on 14 February 2018

Latency-associated nuclear antigen (LANA) of Kaposi's sarcoma-associated herpesvirus interacts with origin recognition complexes at the LANA binding sequence within the terminal repeats

scientific article published on March 2006

Latency-associated nuclear antigen of Kaposi's sarcoma-associated herpesvirus (KSHV) upregulates survivin expression in KSHV-Associated B-lymphoma cells and contributes to their proliferation

scientific article

Latency-associated nuclear antigen of Kaposi's sarcoma-associated herpesvirus recruits uracil DNA glycosylase 2 at the terminal repeats and is important for latent persistence of the virus

scientific article

Latency-associated nuclear antigen of Kaposi's sarcoma-associated herpesvirus up-regulates transcription of human telomerase reverse transcriptase promoter through interaction with transcription factor Sp1.

scientific article

MTA1 expression is linked to ovarian cancer

scientific article published on 30 September 2008

Major Histocompatibility Complex Class II HLA-DRα Is Downregulated by Kaposi's Sarcoma-Associated Herpesvirus-Encoded Lytic Transactivator RTA and MARCH8.

scientific article published on 29 June 2016

Mechanisms of B-Cell Oncogenesis Induced by Epstein-Barr Virus

scientific article published on 14 June 2019

Metabolic reprogramming of Kaposi's sarcoma associated herpes virus infected B-cells in hypoxia.

scientific article

Metagenomic assay for identification of microbial pathogens in tumor tissues

scientific article

Microbial Signatures Associated with Oropharyngeal and Oral Squamous Cell Carcinomas

scientific article

Microbiome signatures in prostate cancer

scientific article published on 01 July 2019

Molecular Biology of EBV in Relationship to HIV/AIDS-Associated Oncogenesis

scientific article published on 01 January 2019

Molecular Biology of Kaposi's Sarcoma-associated Herpesvirus and Related Oncogenesis ⬇️

scientific article published on January 1, 2010

Molecular biology and pathogenesis of Kaposi sarcoma-associated herpesvirus

scientific article

Molecular biology of EBV in relationship to AIDS-associated oncogenesis.

scientific article

Molecular biology of Kaposi's sarcoma-associated herpesvirus

scientific article

Molecular genetics of herpesviruses: a recombinant technology approach.

scientific article published in January 2005

Multiple oncogenic viruses identified in Ocular surface squamous neoplasia in HIV-1 patients

scientific article

Nm23-H1 can induce cell cycle arrest and apoptosis in B cells

scientific article

Nm23-H1 modulates the activity of the guanine exchange factor Dbl-1

scientific article

Nuclear Localization and Cleavage of STAT6 Is Induced by Kaposi's Sarcoma-Associated Herpesvirus for Viral Latency

scientific article

Nucleoside diphosphate kinase/Nm23 and Epstein-Barr virus

scientific article published on 03 May 2009

ORF73 of Herpesvirus Saimiri Strain C488 Tethers the Viral Genome to Metaphase Chromosomes and Binds to cis -Acting DNA Sequences in the Terminal Repeats ⬇️

scientific article published on December 1, 2003

ORF73 of herpesvirus saimiri, a viral homolog of Kaposi's sarcoma-associated herpesvirus, modulates the two cellular tumor suppressor proteins p53 and pRb.

scientific article published on October 2004

Oncogenic Epstein-Barr virus recruits Nm23-H1 to regulate chromatin modifiers

scientific article published on 16 October 2017

Oncogenic viral prevalence in invasive vulvar cancer specimens from human immunodeficiency virus-positive and -negative women in Botswana

scientific article published on May 2014

Oncogenic viruses associated with vulva cancer in HIV-1 patients in Botswana

scientific article

Proteasomal inhibition triggers viral oncoprotein degradation via autophagy-lysosomal pathway

scientific article published on 24 February 2020

Protein complexes associated with the Kaposi's sarcoma-associated herpesvirus-encoded LANA.

scientific article

Proteomic analysis of the Kaposi's sarcoma-associated herpesvirus terminal repeat element binding proteins

scientific article published on September 2006

Proteomic profiling identifies the SIM-associated complex of KSHV-encoded LANA.

scientific article published on 26 May 2015

Proteomic signatures in laryngeal squamous cell carcinoma

scientific article published on 24 November 2006

Quassinoid analogs with enhanced efficacy for treatment of hematologic malignancies target the PI3Kγ isoform

scientific article published on 27 May 2020

Regulation of Nm23-H1 and Cell Invasiveness by Kaposi's Sarcoma-Associated Herpesvirus ⬇️

scientific article published on January 26, 2011

Regulation of matrix metalloproteinase 9 expression by Epstein-Barr virus nuclear antigen 3C and the suppressor of metastasis Nm23-H1.

scientific article published on August 2005

Regulation of the metastasis suppressor Nm23-H1 by tumor viruses

scientific article published on 10 September 2014

Role of SUMOylation in Human Oncogenic Herpesvirus Infection

scientific article published on 10 April 2020

SCFSkp2 complex targeted by Epstein-Barr virus essential nuclear antigen

scientific article

STAT6 degradation and ubiquitylated TRIML2 are essential for activation of human oncogenic herpesvirus

scientific article published on 10 December 2018

STUB1 is targeted by the SUMO-interacting motif of EBNA1 to maintain Epstein-Barr Virus latency

scientific article published on 16 March 2020

Shugoshin 1 is dislocated by KSHV-encoded LANA inducing aneuploidy

scientific article published on 13 September 2018

Single molecule analysis of replicated DNA reveals the usage of multiple KSHV genome regions for latent replication

scientific article

Small molecule growth inhibitors of human oncogenic gammaherpesvirus infected B-cells

scientific article

Survival of the fittest: a role for phage‐encoded eukaryotic‐like kinases ⬇️

scientific article published on October 12, 2011

Targeted Therapies for Epstein-Barr Virus-Associated Lymphomas

scientific article published on 09 September 2020

The ATM/ATR signaling effector Chk2 is targeted by Epstein-Barr virus nuclear antigen 3C to release the G2/M cell cycle block

scientific article published on 4 April 2007

The Crosstalk of Epigenetics and Metabolism in Herpesvirus Infection

scientific article published on 01 December 2020

The EBV Latent Antigen 3C Inhibits Apoptosis through Targeted Regulation of Interferon Regulatory Factors 4 and 8.

scientific article

The Epstein Barr nuclear antigen EBNA3C regulates transcription, cell transformation and cell migration

scientific article

The RBP-Jκ binding sites within the RTA promoter regulate KSHV latent infection and cell proliferation

scientific article

The Role of Gammaherpesviruses in Cancer Pathogenesis

scientific article

The Single RBP-Jκ Site within the LANA Promoter Is Crucial for Establishing Kaposi's Sarcoma-Associated Herpesvirus Latency during Primary Infection ⬇️

scientific article published on April 20, 2011

The metastatic suppressor Nm23-H1 interacts with EBNA3C at sequences located between the glutamine- and proline-rich domains and can cooperate in activation of transcription

scientific article

The minimal replicator element of the Kaposi's sarcoma-associated herpesvirus terminal repeat supports replication in a semiconservative and cell-cycle-dependent manner

scientific article published on 6 December 2006

The ovarian cancer oncobiome

scientific article

The suppressor of metastasis Nm23-H1 interacts with the Cdc42 Rho family member and the pleckstrin homology domain of oncoprotein Dbl-1 to suppress cell migration

scientific article

The virome of HPV-positive tonsil squamous cell carcinoma and neck metastasis

scientific article published on 21 January 2020

Transcriptional and epigenetic modulation of autophagy promotes EBV oncoprotein EBNA3C induced B-cell survival.

scientific article

Tumor viruses and cancer biology: Modulating signaling pathways for therapeutic intervention

scientific article

Ubiquitin/SUMO Modification Regulates VHL Protein Stability and Nucleocytoplasmic Localization ⬇️

scientific article published on September 9, 2010

Upregulation of Cellular Bcl-2 by the KSHV Encoded RTA Promotes Virion Production ⬇️

scientific article published on August 25, 2011

Vascular endothelial growth factor encoded by Parapoxviruses can regulate metabolism and survival of triple negative breast cancer cells

scientific article published on 20 November 2020

Viral-associated trichodysplasia: characterization of a novel polyomavirus infection with therapeutic insights

scientific article

miR-K12-7-5p Encoded by Kaposi's Sarcoma-Associated Herpesvirus Stabilizes the Latent State by Targeting Viral ORF50/RTA ⬇️

scientific article published on January 20, 2011

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