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List of works by Yutaka Osuga

A Japanese nationwide survey on the cryopreservation of embryos, oocytes and ovarian tissue for cancer patients

scientific article published on 30 July 2019

A National Survey of Umbilical Endometriosis in Japan

scientific article published on 06 April 2019

A Potential Role for Endoplasmic Reticulum Stress in Progesterone Deficiency in Obese Women

scientific article published on 25 November 2016

A case of a surviving co-twin diagnosed with porencephaly and renal hypoplasia after a single intrauterine fetal death at 21 weeks of gestation in a monochorionic monoamniotic twin pregnancy

scientific article published on 17 January 2017

A case of estrogen-producing Brenner tumor with a stromal component as a potential source for estrogen

scientific article published in January 2002

A case of functioning gonadotroph adenoma in a reproductive aged woman

scientific article published on 19 April 2019

A case of hemorrhagic shock occurred during dienogest therapy for uterine adenomyosis

scientific article published on 08 October 2020

A case of hydrosalpinx associated with the menstrual cycle

scientific article published on 24 October 2007

A case of lymphangioleiomyomatosis associated with endometrial cancer and severe systemic lupus erythematosus

scientific article

A case of pregnancy complicated with dilated cardiomyopathy 1X.

scientific article

A coexistence case of right tubal adenomyoma and ectopic pregnancy

scientific article published on 27 May 2014

A gene network of uterine luminal epithelium organizes mouse blastocyst implantation

scientific article published on 05 January 2022

A potential role of endoplasmic reticulum stress in development of ovarian hyperstimulation syndrome

scientific article published on 28 March 2016

A survey of public attitudes toward uterus transplantation, surrogacy, and adoption in Japan

scientific article published on 30 October 2019

A survey of public attitudes towards third-party reproduction in Japan in 2014

scientific article published in PLoS ONE

ASK1 promotes uterine inflammation leading to pathological preterm birth

scientific article published on 05 February 2020

Abdominal compartment syndrome complicated by preeclampsia and partial HELLP syndrome in a 45-year-old woman: A case report

scientific article published on 28 April 2020

Aberrant implantation and growth of uterine leiomyoma in the abdominal wall after laparoscopically assisted myomectomy

scientific article published on 17 September 2009

Accumulation of advanced glycation end products in follicles is associated with poor oocyte developmental competence

scientific article published on 01 November 2019

Acquired contractile ability in human endometrial stromal cells by passive loading of cyclic tensile stretch

scientific article published on 02 June 2020

Activation of Endoplasmic Reticulum Stress in Granulosa Cells from Patients with Polycystic Ovary Syndrome Contributes to Ovarian Fibrosis.

scientific article published on 7 September 2017

Activation of Nrf2 might reduce oxidative stress in human granulosa cells

scientific article

Activation of Nrf2/Keap1 pathway by oral Dimethylfumarate administration alleviates oxidative stress and age-associated infertility might be delayed in the mouse ovary

article

Activation of endoplasmic reticulum stress mediates oxidative stress-induced apoptosis of granulosa cells in ovaries affected by endometrioma

scientific article published on 01 January 2020

Activation of protease-activated receptor 2 stimulates proliferation and interleukin (IL)-6 and IL-8 secretion of endometriotic stromal cells

scientific article published on 11 August 2005

Activin-A is induced by interleukin-1β and tumor necrosis factor-α and enhances the mRNA expression of interleukin-6 and protease-activated receptor-2 and proliferation of stromal cells from endometrioma

scientific article published on 2 June 2011

Adenomyosis and adverse perinatal outcomes: increased risk of second trimester miscarriage, preeclampsia, and placental malposition

scientific article published on 23 January 2017

Administration of Oral Contraceptives Could Alleviate Age-Related Fertility Decline Possibly by Preventing Ovarian Damage in a Mouse Model

scientific article published in January 2017

Akt as a possible intracellular mediator for decidualization in human endometrial stromal cells

scientific article published in May 2003

Alpha-7 nicotinic acetylcholine receptor (nAChR) agonist inhibits the development of endometriosis by regulating inflammation

scientific article published on 21 October 2016

Alternative strategies to in vitro fertilization/intracytoplasmic sperm injection treatment for aged infertile women.

scientific article published on 13 August 2011

Androgen insensitivity syndrome with serous gonadal cyst

scientific article published on 9 August 2008

Androgens Increase Accumulation of Advanced Glycation End Products in Granulosa Cells by Activating ER Stress in PCOS

scientific article published on 01 February 2020

Annual report of Reproductive Endocrinology Committee, Japan Society of Obstetrics and Gynecology, 2019

scientific article published on 09 August 2019

Anti-Mullerian hormone (AMH) is induced by bone morphogenetic protein (BMP) cytokines in human granulosa cells ⬇️

scientific article published on June 8, 2012

Anti-Tumor Effect of Inhibition of DNA Damage Response Proteins, ATM and ATR, in Endometrial Cancer Cells

scientific article published on 01 December 2019

Anti-tumor activity of dual inhibition of phosphatidylinositol 3-kinase and MDM2 against clear cell ovarian carcinoma

scientific article published on 05 September 2019

Anti-tumor activity of olaparib, a poly (ADP-ribose) polymerase (PARP) inhibitor, in cultured endometrial carcinoma cells

scientific article

Antitumor activity and induction of TP53-dependent apoptosis toward ovarian clear cell adenocarcinoma by the dual PI3K/mTOR inhibitor DS-7423.

scientific article published on 04 February 2014

Antitumor activity of a combination of dual PI3K/mTOR inhibitor SAR245409 and selective MEK1/2 inhibitor pimasertib in endometrial carcinomas.

scientific article published on 29 May 2015

Application of detergents or high hydrostatic pressure as decellularization processes in uterine tissues and their subsequent effects on in vivo uterine regeneration in murine models

scientific article

Assisted reproductive technology pregnancy complications are significantly associated with endometriosis severity before conception: a retrospective cohort study.

scientific article

Authors' reply re: Peripartum type B aortic dissection in patients with Marfan syndrome who underwent aortic root replacement: a case series study

scientific article published on 10 August 2017

Autoamputated adnexa presents as a peritoneal loose body

scientific article published on 25 April 2009

Autophagy inhibition augments resveratrol-induced apoptosis in Ishikawa endometrial cancer cells.

scientific article published on 08 August 2016

Basic and translational research on proteinase-activated receptors: proteinase-activated receptors in female reproductive tissues and endometriosis

scientific article published in December 2008

Bevacizumab-Related Microvascular Angina and Its Management with Nicorandil

scientific article

Blood Vessel Invasion Is a Strong Predictor of Postoperative Recurrence in Endometrial Cancer

scientific article published on 01 June 2018

Bone morphogenetic protein 7 (BMP-7) increases the expression of follicle-stimulating hormone (FSH) receptor in human granulosa cells

scientific article

Bone morphogenetic protein 7 increased vascular endothelial growth factor (VEGF)-a expression in human granulosa cells and VEGF receptor expression in endothelial cells.

scientific article published on 10 September 2013

Bone morphogenetic protein-2 (BMP-2) increases gene expression of FSH receptor and aromatase and decreases gene expression of LH receptor and StAR in human granulosa cells

scientific article published on 6 September 2010

Bone morphogenetic protein-6 stimulates gene expression of follicle-stimulating hormone receptor, inhibin/activin beta subunits, and anti-Müllerian hormone in human granulosa cells

scientific article published on 21 June 2009

CCAR2 negatively regulates nuclear receptor LXRα by competing with SIRT1 deacetylase

scientific article

CD11c+ M1-like macrophages (MΦs) but not CD206+ M2-like MΦ are involved in folliculogenesis in mice ovary.

scientific article

CD206+ M2-Like Macrophages Are Essential for Successful Implantation

scientific article published on 23 October 2020

Cancer-associated fibroblast suppresses killing activity of natural killer cells through downregulation of poliovirus receptor (PVR/CD155), a ligand of activating NK receptor

scientific article published on 26 July 2016

Cancers associated with extraovarian endometriosis at less common/rare sites: A nationwide survey in Japan

scientific article published on 25 March 2020

Case of chronic ectopic pregnancy diagnosed in which the complete shape of the fetus was visible by ultrasonography

scientific article published on 01 April 2010

Cellular mechanisms of growth inhibition of human endometrial cancer cell line by an antagonist of growth hormone-releasing hormone

scientific article

Cellular mechanisms of growth inhibition of human epithelial ovarian cancer cell line by LH-releasing hormone antagonist Cetrorelix

scientific article published on August 2002

Cervical Expression of Elafin and SLPI in Pregnancy and Their Association With Preterm Labor.

scientific article published on 5 January 2015

Characteristic images of deeply infiltrating rectosigmoid endometriosis on transvaginal and transrectal ultrasonography.

scientific article

Characterization of TP53 and PI3K signaling pathways as molecular targets in gynecologic malignancies

scientific article published on 20 April 2016

Characterization of novel transcripts of human papillomavirus type 16 using cap analysis gene expression technology

scientific article

Clinical aspects and management of inguinal endometriosis: A case series of 20 patients

scientific article published on 05 August 2019

Clinical practice guidelines for the treatment of extragenital endometriosis in Japan, 2018

scientific article published on 20 October 2020

Clinical significance of Gremlin 1 in cervical cancer and its effects on cancer stem cell maintenance.

scientific article published on 30 October 2015

Clinical studies investigating the use of leuprorelin in Asian women with endometriosis: a review

scientific article published on 17 January 2019

Combined phospho-Akt and PTEN expressions associated with post-treatment hysterectomy after conservative progestin therapy in complex atypical hyperplasia and stage Ia, G1 adenocarcinoma of the endometrium

scientific article published on 21 August 2006

Comprehensive immunohistochemical analysis of the gastrointestinal and Müllerian phenotypes of 139 ovarian mucinous cystadenomas

scientific article published on 01 December 2020

Concentration of adiponectin in peritoneal fluid is decreased in women with endometriosis

scientific article published on 01 October 2005

Concentration of osteoprotegerin (OPG) in peritoneal fluid is increased in women with endometriosis

scientific article published on 8 July 2004

Concentrations of interferon-gamma-induced protein-10 (IP-10), an antiangiogenic substance, are decreased in peritoneal fluid of women with advanced endometriosis

scientific article published on 01 July 2003

Concomitant ovarian drilling and oocyte retrieval by laparoendoscopic single-site surgery led to live birth using in vitro maturation of oocyte and transfer of frozen-thawed blastocyst in woman with polycystic ovary syndrome

scientific article published in May 2014

Congenital extracardiac venous system anomaly in two siblings with normal karyotype and increased nuchal translucency thickness: a case report

scientific article published on 13 June 2020

Conjoined twins in a triplet pregnancy after intracytoplasmic sperm injection and blastocyst transfer: case report and review of the literature

scientific article

Contralateral ovarian endometrioma recurrence after unilateral salpingo-oophorectomy

scientific article published on 02 May 2019

Correction: Integrated Copy Number and Expression Analysis Identifies Profiles of Whole-Arm Chromosomal Alterations and Subgroups with Favorable Outcome in Ovarian Clear Cell Carcinomas

scientific article published on 6 July 2015

Cost-effectiveness of the recommended medical intervention for the treatment of dysmenorrhea and endometriosis in Japan.

scientific article

Cross-Talk between Fas/Fas ligand system and nitric oxide in the pathway subserving granulosa cell apoptosis: a possible regulatory mechanism for ovarian follicle atresia

scientific article published on 4 November 2004

Current concepts of the pathogenesis of endometriosis.

scientific article

Cyclic stretch augments production of neutrophil chemokines and matrix metalloproteinase-1 in human uterine smooth muscle cells

scientific article published on 17 December 2012

Cyclic stretch augments production of neutrophil chemokines and matrix metalloproteinases-1 (MMP-1) from human decidual cells, and the production was reduced by progesterone

scientific article published on 19 February 2013

Cyclic stretch augments production of neutrophil chemokines, matrix metalloproteinases, and activin a in human endometrial stromal cells

scientific article published on 21 January 2015

Cytotrophoblasts up-regulate soluble fms-like tyrosine kinase-1 expression under reduced oxygen: an implication for the placental vascular development and the pathophysiology of preeclampsia

scientific article published on 29 July 2004

Death effector domain-containing protein (DEDD) is required for uterine decidualization during early pregnancy in mice

scientific journal article

Decreased expression of the plasminogen activator inhibitor type 1 is involved in degradation of extracellular matrix surrounding cervical cancer stem cells.

scientific article published on 9 December 2015

Deep endometriosis infiltrating the recto-sigmoid: critical factors to consider before management

scientific article

Deficiency of immunophilin FKBP52 promotes endometriosis

scientific article

Desensitization strategy for hypersensitivity reactions to carboplatin in five patients with gynecological cancer

scientific article published on 23 August 2020

Desmoid Tumor at the Site of Endometriosis Surgery, Coincident with the Use of Oral Contraceptives

scientific article published on 07 June 2019

Detachment from the primary site and suspension in ascites as the initial step in metabolic reprogramming and metastasis to the omentum in ovarian cancer

scientific article published on 9 November 2017

Development of an experimental model of endometriosis using mice that ubiquitously express green fluorescent protein

scientific article published on 14 April 2005

Development of endometrioma after cervical conization

scientific article published on 26 October 2017

Development of ovarian cancer after excision of endometrioma.

scientific article published on 17 August 2016

Diameter of dominant leiomyoma is a possible determinant to predict coexistent endometriosis.

scientific article published on 27 February 2012

Dienogest inhibits BrdU uptake with G0/G1 arrest in cultured endometriotic stromal cells

scientific article published on 23 May 2007

Dienogest reduces proliferation, NGF expression and nerve fiber density in human adenomyosis

scientific article published on 8 November 2016

Dienogest reduces proliferation, aromatase expression and angiogenesis, and increases apoptosis in human endometriosis

scientific article published on 07 May 2014

Dienogest suppresses cellular proliferation status of endometrial polyps and acts differently depending on the morphological type

scientific article published on 01 January 2020

Dienogest, a new conservative strategy for extragenital endometriosis: a pilot study

scientific article

Differential expression of human papillomavirus 16-, 18-, 52-, and 58-derived transcripts in cervical intraepithelial neoplasia

scientific article published on 06 March 2020

Differential roles of uterine epithelial and stromal STAT3 coordinate uterine receptivity and embryo attachment

scientific article published on 23 September 2020

Distribution of the follicular and luteal phase lengths and their age‐dependent changes in Japanese women: A large population study

scientific article published in 2023

Drospirenone induces decidualization in human eutopic endometrial stromal cells and reduces DNA synthesis of human endometriotic stromal cells.

scientific article published on 29 April 2015

Drospirenone reduces inflammatory cytokines, vascular endothelial growth factor (VEGF) and nerve growth factor (NGF) expression in human endometriotic stromal cells

scientific article published on 29 December 2016

Effect of MDM2 inhibitors in preclinical models of advanced clear cell carcinomas originating from ovaries and kidneys

scientific article published on 25 July 2020

Effect of transdermal estradiol therapy on bone mineral density of amenorrheic athletes

scientific article published on 14 April 2020

Effects of 1,25-Dihydroxy Vitamin D3 on Endometriosis.

scientific article published in April 2016

Efficacy and safety of ASP1707 for endometriosis-associated pelvic pain: the phase II randomized controlled TERRA study

article published in 2019

Efficacy of dienogest in the treatment of symptomatic adenomyosis: a pilot study

scientific article published on 06 June 2014

Elective single-embryo transfer improves cumulative pregnancy outcome in young patients but not in women of advanced reproductive age.

scientific article

Elevated Serum Soluble Vascular Endothelial Growth Factor Receptor 1 (sVEGFR-1) Levels in Women with Preeclampsia

scientific article published on 01 May 2003

Elevated concentration of secretory leukocyte protease inhibitor in the cervical mucus before delivery

scientific article published on 14 January 2016

Elevated interleukin-16 levels in the peritoneal fluid of women with endometriosis may be a mechanism for inflammatory reactions associated with endometriosis

scientific article published on 01 April 2005

Elevated serum soluble fms-like tyrosine kinase 1 (sFlt1) level in women with hydatidiform mole

scientific article published on 9 March 2009

Elevation of maternal serum sFlt-1 in pregnancy with mirror syndrome caused by fetal cardiac failure.

scientific article

Emerging roles for lysophospholipid mediators in pregnancy

scientific article published on April 2014

Endometrial stromal cells undergoing decidualization down-regulate their properties to produce proinflammatory cytokines in response to interleukin-1 beta via reduced p38 mitogen-activated protein kinase phosphorylation.

scientific article published in May 2003

Endometriosis Triggers Excessive Activation of Primordial Follicles via PI3K-PTEN-Akt-Foxo3 Pathway

scientific article published on 01 November 2019

Endoplasmic Reticulum Stress Activated by Androgen Enhances Apoptosis of Granulosa Cells via Induction of Death Receptor 5 in PCOS

scientific article published on 01 January 2019

Endoplasmic reticulum stress: a key regulator of the follicular microenvironment in the ovary

scientific article published on 07 January 2021

Enhanced HIF2α expression during human trophoblast differentiation into syncytiotrophoblast suppresses transcription of placental growth factor

scientific article published on 29 September 2017

Epigenetic Modifier SETD8 as a Therapeutic Target for High-Grade Serous Ovarian Cancer

scientific article published on 16 December 2020

Establishment and Molecular Phenotyping of Organoids from the Squamocolumnar Junction Region of the Uterine Cervix

scientific article published on 15 March 2020

Evidence for the presence of angiogenin in human testis

scientific article published in May 2004

Evidence for the presence of protease-activated receptor 2 and its possible implication in remodeling of human endometrium

scientific article published on 7 December 2004

Evidence for the presence of toll-like receptor 4 system in the human endometrium

scientific article published on 27 October 2004

Evidence of the activation of unfolded protein response in granulosa and cumulus cells during follicular growth and maturation.

scientific article

Expression and possible implication of growth hormone-releasing hormone receptor splice variant 1 in endometriosis

scientific article

Expression and regulation of cholesterol sulfotransferase (SULT2B1b) in human endometrium

scientific article published on 24 February 2009

Expression and regulation of periostin/OSF-2 gene in rat uterus and human endometrium

scientific journal article

Expression of ALDH1A Isozymes in Human Endometrium with and without Endometriosis and in Ovarian Endometrioma

scientific article published on 01 January 2020

Expression of Nerve Injury-Induced Protein1 (Ninj1) in Endometriosis

article

Expression of Par3 polarity protein correlates with poor prognosis in ovarian cancer

scientific article

Expression of adiponectin receptors and its possible implication in the human endometrium

scientific article published on 06 April 2006

Expression of retinoic acid-related orphan receptor alpha and its responsive genes in human endometrium regulated by cholesterol sulfate ⬇️

scientific article published on October 17, 2011

Expression of the glucagon-like peptide-1 receptor and its role in regulating autophagy in endometrial cancer.

scientific article

Expression of toll-like receptors 2, 3, 4, and 9 genes in the human endometrium during the menstrual cycle

scientific article published on 12 February 2007

Extra-pelvic endometriosis: A review

scientific article published on 16 July 2020

F4/80+ Macrophages Contribute to Clearance of Senescent Cells in the Mouse Postpartum Uterus

scientific article published on 18 May 2017

FR 167653, a p38 mitogen-activated protein kinase inhibitor, suppresses the development of endometriosis in a murine model

scientific article published on 04 August 2006

Factors that predict poor clinical course among patients hospitalized with pelvic inflammatory disease

scientific article

Fertility Preservation in Patients Receiving Gonadotoxic Therapies for Systemic Autoimmune Diseases in Japan

scientific article published on 25 November 2020

Fertility preservation for female cancer patients

scientific article published on 03 March 2018

Follistatin is induced by IL-1β and TNF-α in stromal cells from endometrioma.

scientific article published on 19 November 2012

Four Cases of Postoperative Pneumothorax Among 2814 Consecutive Laparoscopic Gynecologic Surgeries: A Possible Correlation Between Postoperative Pneumothorax and Endometriosis.

scientific article published on 30 April 2015

Genome-wide cDNA microarray analysis of gene-expression profiles involved in ovarian endometriosis

scientific article published on 01 March 2003

GnRH II as a possible cytostatic regulator in the development of endometriosis

scientific article published on 21 July 2005

Growth differentiation factor 3 is induced by bone morphogenetic protein 6 (BMP-6) and BMP-7 and increases luteinizing hormone receptor messenger RNA expression in human granulosa cells.

scientific article published on 2 February 2012

HAND2-mediated proteolysis negatively regulates the function of estrogen receptor α.

scientific article published on 9 July 2015

HIF2α in the uterine stroma permits embryo invasion and luminal epithelium detachment

scientific article published on 18 June 2018

HPV-16 impairs the subcellular distribution and levels of expression of protein phosphatase 1γ in cervical malignancy

scientific article

High incidence of tubal dysfunction is determined by laparoscopy in cases with positive Chlamydia trachomatis antibody despite negative finding in prior hysterosalpingography.

scientific article

High mobility group box 1 (HMGB1) levels in the placenta and in serum in preeclampsia

scientific article published on 18 January 2011

High soluble CD44 concentration in peritoneal fluid in endometriosis

scientific article published on 24 October 2007

Histone methyltransferase SMYD2 selective inhibitor LLY-507 in combination with poly ADP ribose polymerase inhibitor has therapeutic potential against high-grade serous ovarian carcinomas

scientific article published on 04 April 2019

Huge pyogenic cervical cyst with endometriosis, developing 13 years after myomectomy at the lower uterine segment: a case report

scientific article

Human chorionic gonadotropin combined with progesterone for luteal support improves pregnancy rate in patients with low late-midluteal estradiol levels in IVF cycles

scientific article

Hyaluronic acid reagent suppressed endometriotic lesion formation in a mouse model

scientific article published on 31 March 2010

Hypoxia does not reduce HLA-G expression on extravillous cytotrophoblasts

scientific article published on 01 October 2004

IFITM1 is a Novel, Highly Sensitive Marker for Endometriotic Stromal Cells in Ovarian and Extragenital Endometriosis

scientific article published on 20 May 2020

IFITM1 is a Novel, Highly Sensitive Marker for Endometriotic Stromal Cells in Ovarian and Extragenital Endometriosis

scientific article published on 21 February 2019

IL-1β increases expression of tryptophan 2,3-dioxygenase and stimulates tryptophan catabolism in endometrioma stromal cells

scientific article published on 26 June 2014

IL-33 Exacerbates Endometriotic Lesions via Polarizing Peritoneal Macrophages to M2 Subtype

scientific article published on 07 January 2020

Identifying patients who can improve fertility with myomectomy.

scientific article published on 2 December 2014

Images in reproductive medicine. A case of giant cystic adenomyosis

scientific article published on 01 March 2006

Impact of Th1/Th2 cytokine polarity induced by invariant NKT cells on the incidence of pregnancy loss in mice.

scientific article

Impact of additional risk factors on the incidence of preterm delivery among pregnant women diagnosed with short cervix

scientific article published on 01 March 2020

Increased LIGHT leading to sFlt-1 elevation underlies the pathogenic link between hydatidiform mole and preeclampsia

scientific article published on 12 July 2019

Increased production of inflammatory cytokines and activation of microglia in the fetal brain of preeclamptic mice induced by angiotensin II

scientific article published in 2022

Increased risk of placenta previa is associated with endometriosis and tubal factor infertility in assisted reproductive technology pregnancy ⬇️

scientific article published on July 26, 2012

Increased risk of pregnancy-induced hypertension and operative delivery after conception induced by in vitro fertilization/intracytoplasmic sperm injection in women aged 40 years and older

scientific article published on 11 August 2014

Increased tissue levels of omega-3 polyunsaturated fatty acids prevents pathological preterm birth

scientific article

Individualized management of umbilical endometriosis: a report of seven cases.

scientific article published on 15 August 2013

Infertility treatment hinders the careers of working women in Japan

scientific article published on 17 August 2020

Inhibition of autophagy in theca cells induces CYP17A1 and PAI-1 expression via ROS/p38 and JNK signalling during the development of polycystic ovary syndrome

scientific article published on 19 March 2020

Inhibition of endoplasmic reticulum (ER) stress sensors sensitizes cancer stem-like cells to ER stress-mediated apoptosis

scientific article published on 17 June 2016

Integrated copy number and expression analysis identifies profiles of whole-arm chromosomal alterations and subgroups with favorable outcome in ovarian clear cell carcinomas

scientific article published on 4 June 2015

Interleukin (IL)-17A stimulates IL-8 secretion, cyclooxygensase-2 expression, and cell proliferation of endometriotic stromal cells

scientific article published on 13 December 2007

Interleukin (IL)-1beta stimulates migration and survival of first-trimester villous cytotrophoblast cells through endometrial epithelial cell-derived IL-8.

scientific article published on 11 September 2008

Interleukin-17 is associated with expression of programmed cell death 1 ligand 1 in ovarian carcinoma

scientific article published on 24 September 2019

Interleukin-17A is present in neutrophils in endometrioma and stimulates the secretion of growth-regulated oncogene-α (Gro-α) from endometrioma stromal cells.

scientific article

Interleukin-17F increases the secretion of interleukin-8 and the expression of cyclooxygenase 2 in endometriosis

scientific article published on 20 May 2011

Interleukin-1β stimulates the secretion of thymic stromal lymphopoietin (TSLP) from endometrioma stromal cells: possible involvement of TSLP in endometriosis.

scientific article

Interleukin-4 and prostaglandin E2 synergistically up-regulate 3β-hydroxysteroid dehydrogenase type 2 in endometrioma stromal cells

scientific article published on 28 February 2013

Interleukin-4 induces expression of eotaxin in endometriotic stromal cells.

scientific article

Interleukin-4 stimulates proliferation of endometriotic stromal cells

scientific article published on 3 July 2008

Intracellular signaling entropy can be a biomarker for predicting the development of cervical intraepithelial neoplasia

scientific article

Intraperitoneal neutrophils activated by KRAS-induced ovarian cancer exert antitumor effects by modulating adaptive immunity

scientific article published on 26 July 2018

Involvement of immune cells in the pathogenesis of endometriosis.

scientific article published on 5 January 2018

Is endometriosis really associated with pain?

scientific article published in January 2002

Japanese GWAS identifies variants for bust-size, dysmenorrhea, and menstrual fever that are eQTLs for relevant protein-coding or long non-coding RNAs.

scientific article

KRAS mutations in uterine endometrium are associated with gravidity and parity

scientific article published on 11 May 2020

Kaempferol, a natural dietary flavonoid, suppresses 17β-estradiol-induced survivin expression and causes apoptotic cell death in endometrial cancer

Labor prediction based on the expression patterns of multiple genes related to cervical maturation in human term pregnancy.

scientific article published on 30 May 2017

Laparoendoscopic single-site concomitant surgery for gallstones and a giant ovarian teratoma

scientific article

Laparoscopic excision of ovarian endometrioma does not exert a qualitative effect on ovarian function: insights from in vitro fertilization and single embryo transfer cycles

scientific article published on 11 March 2015

Laparoscopic ovarian-sparing surgery for a young woman with an exophytic ovarian fibroma.

scientific article published on 22 July 2013

Levonorgestrel Inhibits Embryo Attachment by Eliminating Uterine Induction of Leukemia Inhibitory Factor

scientific article published on 01 February 2020

Long-term dienogest administration in patients with symptomatic adenomyosis

scientific article published on 29 May 2018

Long-term use of dienogest in the treatment of painful symptoms in adenomyosis.

scientific article published on 24 July 2017

Low Bone Mineral Density in Elite Female Athletes With a History of Secondary Amenorrhea in Their Teens

scientific article published on 26 March 2018

Low uptake of fluorodeoxyglucose in positron emission tomography/computed tomography in ovarian clear cell carcinoma may reflect glutaminolysis of its cancer stem cell-like properties.

scientific article published on 20 January 2017

Lymphocytes in endometriosis.

scientific article published on January 2011

MDM2 is a potential therapeutic target and prognostic factor for ovarian clear cell carcinomas with wild type TP53.

scientific article published on 21 September 2016

Management of a pregnant woman with hypouricemia: a case report

scientific article published on 31 May 2019

Management of the female athlete triad

scientific article published on 02 April 2018

Mannose receptor is highly expressed by peritoneal dendritic cells in endometriosis.

scientific article published on 25 October 2016

Matrix metalloproteinase (MMP)-9 in cancer-associated fibroblasts (CAFs) is suppressed by omega-3 polyunsaturated fatty acids in vitro and in vivo

scientific article

Mdm2-p53-SF1 pathway in ovarian granulosa cells directs ovulation and fertilization by conditioning oocyte quality

scientific article published on 27 September 2018

Measurement of endometrial thickness by transvaginal ultrasonography to predict pathological response to medroxyprogesterone acetate in patients with grade 1 endometrioid adenocarcinoma

scientific article published on 28 January 2016

Mechanical stretch stimulates interleukin-8 production in endometrial stromal cells: possible implications in endometrium-related events.

scientific article published on 7 December 2004

Mechanical stretch upregulates IGFBP-1 secretion from decidualized endometrial stromal cells

scientific article published on 23 August 2005

Metformin suppresses interleukin (IL)-1beta-induced IL-8 production, aromatase activation, and proliferation of endometriotic stromal cells

scientific article published on 15 May 2007

MicroRNA-200a locally attenuates progesterone signaling in the cervix, preventing embryo implantation.

scientific article

Mixed endometrioid and clear cell carcinoma arising from laparoscopic trocar site endometriosis

scientific article published on 10 June 2019

Modification of the Tumor Microenvironment in KRAS or c-MYC-Induced Ovarian Cancer-Associated Peritonitis

scientific article

Multistate Markov Model to Predict the Prognosis of High-Risk Human Papillomavirus-Related Cervical Lesions

scientific article published on 22 January 2020

Myomectomy decreases abnormal uterine peristalsis and increases pregnancy rate

scientific article published on 09 November 2011

Myomectomy reduces endometrial T2 relaxation times

scientific article published on 11 February 2011

Müllerian cyst of the uterus treated with laparoscopy and diagnosed using immunohistology

scientific article published on July 29, 2012

National survey of bladder endometriosis cases in Japan

scientific article published on 04 January 2021

National survey of primary amenorrhea and relevant conditions in Japan

scientific article published on 16 December 2020

Nationwide survey of fertility preservation in patients with hematological malignancies in Japan

scientific article published on 17 October 2020

Neutrophil depletion reduces endometriotic lesion formation in mice.

scientific article published on 19 July 2016

Nomenclature of primary amenorrhea: A proposal document of the Japan Society of Obstetrics and Gynecology committee for the redefinition of primary amenorrhea.

scientific article

Non-diethylstilbestrol exposed vaginal clear cell adenocarcinoma has a common molecular profile with ovarian clear cell adenocarcinoma: A case report

scientific article published on 5 June 2014

Novel therapeutic strategies for endometriosis: a pathophysiological perspective

scientific article published on 21 October 2008

Oil-Soluble Contrast Medium (OSCM) for Hysterosalpingography Modulates Dendritic Cell and Regulatory T Cell Profiles in the Peritoneal Cavity: A Possible Mechanism by Which OSCM Enhances Fertility.

scientific article published on 28 April 2017

Omega-3 polyunsaturated Fatty acids suppress the cystic lesion formation of peritoneal endometriosis in transgenic mouse models

scientific article

On-chip immunofluorescence analysis of single cervical cells using an electroactive microwell array with barrier for cervical screening ⬇️

scientific article published on 30 July 2019

Oncogenic histone methyltransferase EZH2: A novel prognostic marker with therapeutic potential in endometrial cancer

scientific article published on 17 March 2017

Oral Gonadotropin-Releasing Hormone Antagonist Relugolix Compared With Leuprorelin Injections for Uterine Leiomyomas: A Randomized Controlled Trial.

scientific article published in March 2019

Oral contraceptive therapy reduces serum relaxin-2 in elite female athletes

scientific article published on 27 December 2016

Oral vaccination against HPV E7 for treatment of cervical intraepithelial neoplasia grade 3 (CIN3) elicits E7-specific mucosal immunity in the cervix of CIN3 patients

scientific article published on 22 September 2014

Ovarian hyperstimulation syndrome complicated by peritonitis due to perforated appendicitis

scientific article

PAI-1 in granulosa cells is suppressed directly by statin and indirectly by suppressing TGF-β and TNF-α in mononuclear cells by insulin-sensitizing drugs

scientific article

PAX8: A Highly Sensitive Marker for the Glands in Extragenital Endometriosis

scientific article published on 19 May 2020

PAX8: A Highly Sensitive Marker for the Glands in Extragenital Endometriosis

scientific article published on 14 February 2019

PDZ domains and viral infection: versatile potentials of HPV-PDZ interactions in relation to malignancy

scientific article published on 04 September 2013

PI3K/mTOR pathway inhibition overcomes radioresistance via suppression of the HIF1-α/VEGF pathway in endometrial cancer.

scientific article published on 22 April 2015

Placental autotaxin expression is diminished in women with pre-eclampsia.

scientific article

Placental expression of lysophosphatidic acid receptors in normal pregnancy and preeclampsia

scientific article published on 16 August 2019

Polycystic Ovarian Morphology may be a Positive Prognostic Factor in Patients with Endometrial Cancer who Achieved Complete Remission after Fertility-Sparing Therapy with Progestin

scientific article published on 26 November 2017

Polyhydramnios is associated with postnatal dysphagia determining short-term prognosis of the newborn with 22q11.2 deletion syndrome - A case series analysis

scientific article published on 01 September 2020

Positive peritoneal cytology at interval surgery is a poor prognostic factor in patients with stage T3c advanced ovarian carcinoma: A retrospective study

scientific article published on 25 November 2014

Possible implication of midkine in the development of endometriosis.

scientific article published on 25 February 2005

Possible involvement of thrombin/protease-activated receptor 1 system in the pathogenesis of endometriosis.

scientific article published on 8 March 2005

Possible pathophysiological roles of mitogen-activated protein kinases (MAPKs) in endometriosis.

scientific article published in November 2004

Possible roles of thrombin-induced activation of protease-activated receptor 1 in human luteinized granulosa cells.

scientific article

Pravastatin for preeclampsia: From animal to human

scientific article published on 02 June 2020

Preclinical validation of the new vitrification device possessing a feature of absorbing excess vitrification solution for the cryopreservation of human embryos

scientific article published on 10 January 2020

Prediction of the operative time for hysteroscopic myomectomy for leiomyomas penetrating the intramural cavity using leiomyoma weight and clinical characteristics of patients

scientific article published on 30 September 2018

Predictive factors for recurrence of ovarian mature cystic teratomas after surgical excision

scientific article published on 10 September 2013

Preoperative assessment of factors associated with difficulty in performing total laparoscopic hysterectomy.

scientific article

Prevention of the recurrence of symptom and lesions after conservative surgery for endometriosis

scientific article published on 03 September 2015

Progesterone decreases bone morphogenetic protein (BMP) 7 expression and BMP7 inhibits decidualization and proliferation in endometrial stromal cells.

scientific article published on 18 January 2010

Prognostic importance of CDK4/6-specific activity as a predictive marker for recurrence in patients with endometrial cancer, with or without adjuvant chemotherapy

scientific article published on 10 November 2015

Prolapse of a pedunculated uterine leiomyoma through the cervix during GnRH antagonist treatment: Case report and literature review

scientific article published on 10 September 2020

Proteinase-activated receptors in the endometrium and endometriosis

scientific article published on 01 January 2012

Proteinase-activated receptors in the endometrium and endometriosis.

scientific article published on June 2012

Putative tumor suppression function of SIRT6 in endometrial cancer

scientific article published on 13 July 2015

Quantitative analysis of ovarian cysts and tumors by using T2 star mapping

scientific article published on 19 November 2019

Radical hysterectomy with or without para-aortic lymphadenectomy for patients with stage IB2, IIA2, and IIB cervical cancer: outcomes for a series of 308 patients

scientific article published on 5 October 2015

Recent Progress in Therapeutics for Inflammation-Associated Preterm Birth: A Review

scientific article

Recent advances in targeting DNA repair pathways for the treatment of ovarian cancer and their clinical relevance

scientific article

Recombinant Thrombomodulin Attenuates Preeclamptic Symptoms by Inhibiting High Mobility Group Box 1 in Mice

scientific article published on 06 January 2021

Reconstructed uterine length is critical for the prevention of cervical stenosis following abdominal trachelectomy in cervical cancer patients

scientific article published on 20 January 2020

Recruitment of CCR6-expressing Th17 cells by CCL 20 secreted from IL-1 beta-, TNF-alpha-, and IL-17A-stimulated endometriotic stromal cells.

scientific article

Recurrence of endometrioma after laparoscopic excision and its prevention by medical management

scientific article published on January 2013

Regeneration of cervical reserve cell-like cells from human induced pluripotent stem cells (iPSCs): A new approach to finding targets for cervical cancer stem cell treatment.

scientific article published on 3 April 2017

Regulation of SIRT1 determines initial step of endometrial receptivity by controlling E-cadherin expression

scientific article

Relationship between tartrate-resistant acid phosphatase 5b and stress fractures in female athletes

scientific article published on 15 June 2020

Relaxin-2 May Suppress Endometriosis by Reducing Fibrosis, Scar Formation, and Inflammation

scientific article published on 31 October 2020

Relugolix, a novel oral gonadotropin-releasing hormone antagonist, in the treatment of pain symptoms associated with uterine fibroids: a randomized, placebo-controlled, phase 3 study in Japanese women

scientific article published on 06 October 2019

Relugolix, an oral gonadotropin-releasing hormone receptor antagonist, reduces endometriosis-associated pain in a dose-response manner: a randomized, double-blind, placebo-controlled study

scientific article published on 07 September 2020

Resveratrol Enhances Apoptosis in Endometriotic Stromal Cells.

scientific article published on 19 January 2016

Resveratrol Protects Against Pathological Preterm Birth by Suppression of Macrophage-Mediated Inflammation.

scientific article published on 2 June 2015

Resveratrol suppresses inflammatory responses in endometrial stromal cells derived from endometriosis: a possible role of the sirtuin 1 pathway.

scientific article published on 10 December 2013

Retinoblastoma protein promotes uterine epithelial cell cycle arrest and necroptosis for embryo invasion

scientific article published on 05 January 2021

Rikkunshito attenuates induction of epithelial-mesenchymal switch via activation of Sirtuin1 in ovarian cancer cells

scientific article published on 14 December 2019

Risk factors of stress fractures due to the female athlete triad: Differences in teens and twenties

scientific article published on 09 June 2019

Role of laparoscopy in the treatment of endometriosis-associated infertility

scientific article

Role of oxidative stress in follicular fluid on embryos of patients undergoing assisted reproductive technology treatment

scientific article published on 01 July 2019

SIRT3 positively regulates the expression of folliculogenesis- and luteinization-related genes and progesterone secretion by manipulating oxidative stress in human luteinized granulosa cells.

scientific article

STAT3 accelerates uterine epithelial regeneration in a mouse model of decellularized uterine matrix transplantation.

scientific article published on June 2016

STAT3 activity regulates sensitivity to tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis in cervical cancer cells.

scientific article published on 06 September 2016

Sciatic endometriosis diagnosed by computerized tomography-guided biopsy and CD10 immunohistochemical staining.

scientific article published in November 2005

Secretory leukocyte protease inhibitor and progranulin as possible regulators of cervical remodeling in pregnancy

scientific article published on 01 November 2020

Selective increase in high molecular weight adiponectin concentration in serum of women with preeclampsia

scientific article published on 24 July 2006

Serum Brain-derived Neurotrophic Factor Levels Mirror Bone Mineral Density in Amenorrheic and Eumenorrheic Athletes

scientific article published on 21 February 2019

Serum adiponectin concentrations are decreased in women with endometriosis

scientific article

Sessile polyps and pedunculated polyps respond differently to oral contraceptives

scientific article published on 09 June 2010

Significance of survivin as a prognostic factor and a therapeutic target in endometrial cancer.

scientific article published on 11 April 2016

Simultaneous Detection and Evaluation of Four Subsets of CD4+ T Lymphocyte in Lesions and Peripheral Blood in Endometriosis

scientific article published on 20 September 2015

Singleton pregnancy outcomes after assisted and non-assisted reproductive technology in infertile patients.

scientific article

Spheroid cancer stem cells display reprogrammed metabolism and obtain energy by actively running the tricarboxylic acid (TCA) cycle

scientific article published on 23 April 2016

Sphingosine 1 Phosphate (S1P) Increased IL-6 Expression and Cell Growth in Endometriotic Cells

scientific article published on 19 February 2019

Spontaneous cessation and recurrence of massive uterine bleeding can occur in uterine artery pseudoaneurysm after laparoscopically assisted myomectomy

scientific article published on 25 September 2012

Successful management of a ruptured endometrial cyst in acute leukemia

scientific article published on 18 June 2010

Successful pregnancy following low-dose hCG administration in addition to hMG in a patient with hypothalamic amenorrhea due to weight loss

scientific article published on 21 November 2011

Synergistic antitumor effects of combination PI3K/mTOR and MEK inhibition (SAR245409 and pimasertib) in mucinous ovarian carcinoma cells by fluorescence resonance energy transfer imaging

scientific article published on 18 April 2016

Systemic delivery of siRNA by actively targeted polyion complex micelles for silencing the E6 and E7 human papillomavirus oncogenes

scientific article published on 12 March 2016

TGF-β1 induces proteinase-activated receptor 2 (PAR2) expression in endometriotic stromal cells and stimulates PAR2 activation-induced secretion of IL-6.

scientific article

Targeting glutamine metabolism and the focal adhesion kinase additively inhibits the mammalian target of the rapamycin pathway in spheroid cancer stem-like properties of ovarian clear cell carcinoma in vitro.

scientific article published on 23 February 2017

Temporary balloon occlusion of the uterine arteries to control hemorrhage during hysterectomy in a case of uterine arteriovenous fistula

scientific article published on 17 September 2014

The Emerging Role of FOXL2 in Regulating the Transcriptional Activation Function of Estrogen Receptor β: An Insight Into Ovarian Folliculogenesis.

scientific article published in June 2016

The activity of bisphenol A depends on both the estrogen receptor subtype and the cell type

scientific article published in August 2002

The anti-malarial chloroquine suppresses proliferation and overcomes cisplatin resistance of endometrial cancer cells via autophagy inhibition.

scientific article

The assessment of myometrium perfusion in patients with uterine fibroid by arterial spin labeling MRI.

scientific article

The effects of tokishakuyakusan, a traditional Japanese medicine (kampo), ferulic acid and paeoniflorin, on human endometriotic stromal cells and peritoneal macrophages

scientific article published on 21 February 2020

The efficacy of non-assisted reproductive technology treatment might be limited in infertile patients with advanced endometriosis in their 30s

article

The expression and possible roles of chemokine CXCL11 and its receptor CXCR3 in the human endometrium

scientific article published on 01 December 2006

The function of bone morphogenetic proteins in the human ovary.

scientific article

The histone methyltransferase WHSC1 is regulated by EZH2 and is important for ovarian clear cell carcinoma cell proliferation

scientific article published on 15 May 2019

The impact of elevated thyroid stimulating hormone on female subfertility

scientific article published on 13 August 2015

The influence of infertility treatment on the prognosis of endometrial cancer and atypical complex endometrial hyperplasia

scientific article published in February 2013

The localization and regulation of proprotein convertase subtilisin/kexin (PCSK) 6 in human ovary

scientific article published on 31 August 2012

The oncogene KRAS promotes cancer cell dissemination by stabilizing spheroid formation via the MEK pathway

The outcome of infertility treatment in patients undergoing assisted reproductive technology after conservative therapy for endometrial cancer

scientific article

The presence of midkine and its possible implication in human ovarian follicles

scientific article published on 01 October 2007

The role of bone morphogenetic protein 6 in accumulation and regulation of neutrophils in the human ovary

scientific article

The significance of serum anti-Müllerian hormone (AMH) levels in patients over age 40 in first IVF treatment

scientific article published on 03 May 2013

The three peaks in age distribution of females with pneumothorax: a nationwide database study in Japan

scientific article published on 01 September 2018

Therapeutic significance of targeting survivin in cervical cancer and possibility of combination therapy with TRAIL.

scientific article published on 5 February 2018

Thoracic endometriosis syndrome: Comparison between catamenial pneumothorax or endometriosis-related pneumothorax and catamenial hemoptysis

scientific article published on 20 April 2018

Three cases of clear-cell adenocarcinoma arising from endometrioma during hormonal treatments

scientific article published on 12 July 2018

Thrombin enhances soluble Fms-like tyrosine kinase 1 expression in trophoblasts; possible involvement in the pathogenesis of preeclampsia

scientific article

Tokishakuyakusan, a traditional Japanese medicine (Kampo) mitigates iNKT cell-mediated pregnancy loss in mice

scientific article published on 12 July 2018

Toll-like receptor-3 ligation-induced indoleamine 2, 3-dioxygenase expression in human trophoblasts

scientific article published on 27 September 2011

Toll-like receptors at the maternal-fetal interface in normal pregnancy and pregnancy complications

scientific article published on 23 April 2014

Tunicamycin enhances the apoptosis induced by tumor necrosis factor-related apoptosis-inducing ligand in endometriotic stromal cells

scientific article

Ultrasonographic vascularity assessment for predicting future severe hemorrhage in retained products of conception after second-trimester abortion

scientific article published on 29 April 2019

Upregulation of interleukin-8 by hypoxia in human ovaries.

scientific article published in October 2003

Use of Cap Analysis Gene Expression to detect human papillomavirus promoter activity patterns at different disease stages

scientific article published on 22 October 2020

Use of selective PGE2 receptor antagonists on human endometriotic stromal cells and peritoneal macrophages

scientific article published on 03 December 2020

Usefulness of T2 star-weighted imaging in ovarian cysts and tumors

scientific article published on 30 June 2016

Usefulness of biopsy by office hysteroscopy for endometrial cancer: A case report

scientific article published on 27 May 2020

Usefulness of cell-free and concentrated ascites reinfusion therapy in the therapeutic management of advanced ovarian cancer patients with massive ascites

scientific article published on 24 November 2018

Uterine FK506-binding protein 52 (FKBP52)-peroxiredoxin-6 (PRDX6) signaling protects pregnancy from overt oxidative stress

scientific article

Uterine adenomyosis is an oligoclonal disorder associated with KRAS mutations

scientific article published on 19 December 2019

Uterine arteriovenous fistula treated with repetitive transcatheter embolization: case report

scientific article published on 01 November 2012

Uterine artery pseudoaneurysm after cesarean section: case report and literature review.

scientific article published on 24 July 2010

Uterine epithelial progesterone receptor governs uterine receptivity through epithelial cell differentiation

scientific article published on 25 October 2020

Uterine receptivity, embryo attachment, and embryo invasion: Multistep processes in embryo implantation

scientific article published on 24 May 2019

Vaginal Stenosis After Gonadotropin-Releasing Hormone Agonist Therapy During Treatment for Acute Lymphoblastic Leukemia

scientific article published on 01 April 2016

Vaginal cancer possibly caused by pessary and immunocompromised condition: Multiple risk factors may influence vaginal cancer development.

scientific article

Xanthogranulomatous inflammation of the perimetrium with infiltration into the uterine myometrium in a postmenopausal woman: a case report

scientific article

[Endometriosis]

scientific article published in April 2006

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