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List of works by William Linehan

11C-Acetate PET/CT in localized prostate cancer: a study with MRI and histopathologic correlation

scientific article

A germline 1;3 translocation disrupting the VHL gene: a novel genetic cause for von Hippel-Lindau

scientific article published on 16 October 2020

Abstract 5515: An investigation of risk factors for renal cell carcinoma by histologic subtype in two case-control studies

Alternative splicing of the cell fate determinant Numb in hepatocellular carcinoma

scientific article

An investigation of risk factors for renal cell carcinoma by histologic subtype in two case-control studies

scientific article published on 15 January 2013

Biodistribution and Efficacy of Low Temperature-Sensitive Liposome Encapsulated Docetaxel Combined with Mild Hyperthermia in a Mouse Model of Prostate Cancer

scientific article published on 24 June 2016

Co-opting a Bioorthogonal Reaction for Oncometabolite Detection.

scientific article published on 30 November 2016

Comparison of MR/ultrasound fusion-guided biopsy with ultrasound-guided biopsy for the diagnosis of prostate cancer.

scientific article

Comparison of endorectal coil and nonendorectal coil T2W and diffusion-weighted MRI at 3 Tesla for localizing prostate cancer: correlation with whole-mount histopathology

scientific article

Comprehensive Analysis of Alternative Splicing Across Tumors from 8,705 Patients

article

Comprehensive Characterization of Cancer Driver Genes and Mutations

article

Comprehensive Molecular Characterization of Papillary Renal-Cell Carcinoma

scientific article published on 4 November 2015

Comprehensive genomic and phenotypic characterization of germline FH deletion in hereditary leiomyomatosis and renal cell carcinoma.

scientific article published on 14 February 2017

Consequences of adrenal venous sampling in primary hyperaldosteronism and predictors of unilateral adrenal disease

scientific article

Correlation of magnetic resonance imaging tumor volume with histopathology

scientific article

D'Amico risk stratification correlates with degree of suspicion of prostate cancer on multiparametric magnetic resonance imaging

scientific article

Differential VHL Mutation Patterns in Bilateral Clear Cell RCC Distinguishes Between Independent Primary Tumors and Contralateral Metastatic Disease

scientific article published in 2022

Discovering Targets of Non-enzymatic Acylation by Thioester Reactivity Profiling.

scientific article published on 31 January 2017

Englerin A stimulates PKCθ to inhibit insulin signaling and to simultaneously activate HSF1: pharmacologically induced synthetic lethality

scientific article

Fumarate hydratase deficiency in renal cancer induces glycolytic addiction and hypoxia-inducible transcription factor 1alpha stabilization by glucose-dependent generation of reactive oxygen species.

scientific article published on 26 May 2009

Genomic and metabolic characterization of a chromophobe renal cell carcinoma cell line model (UOK276).

scientific article

Image guidance in the focal treatment of prostate cancer

scientific article published on July 2012

Improved identification of von Hippel-Lindau gene alterations in clear cell renal tumors

scientific article published on August 2008

Increasing reactive oxygen species as a therapeutic approach to treat hereditary leiomyomatosis and renal cell carcinoma ⬇️

scientific article published on October 27, 2010

Low suspicion lesions on multiparametric magnetic resonance imaging predict for the absence of high-risk prostate cancer

scientific article

MRI-Targeted, Systematic, and Combined Biopsy for Prostate Cancer Diagnosis

scientific article published on 01 March 2020

Magnetic resonance imaging (MRI)-guided transurethral ultrasound therapy of the prostate: a preclinical study with radiological and pathological correlation using customised MRI-based moulds

scientific article

Magnetic resonance imaging/ultrasound fusion guided prostate biopsy improves cancer detection following transrectal ultrasound biopsy and correlates with multiparametric magnetic resonance imaging

scientific article

Management of von Hippel-Lindau-associated kidney cancer

scientific article

Metabolic Reprogramming for Producing Energy and Reducing Power in Fumarate Hydratase Null Cells from Hereditary Leiomyomatosis Renal Cell Carcinoma ⬇️

scientific article published on August 15, 2013

Metabolism and oxidative stress response pathways in kidney cancer: a tale of chance and necessity

scientific article

Mitochondrial DNA alterations underlie an irreversible shift to aerobic glycolysis in fumarate hydratase-deficient renal cancer

scientific article published on 05 January 2021

Multiparametric 3T prostate magnetic resonance imaging to detect cancer: histopathological correlation using prostatectomy specimens processed in customized magnetic resonance imaging based molds.

scientific article published on 25 September 2011

Multiparametric Magnetic Resonance Imaging and Ultrasound Fusion Biopsy Detect Prostate Cancer in Patients with Prior Negative Transrectal Ultrasound Biopsies

scientific article (publication date: December 2012)

New strategies in renal cell carcinoma: targeting the genetic and metabolic basis of disease

scientific article published on January 2015

Novel renal medullary carcinoma cell lines, UOK353 and UOK360, provide preclinical tools to identify new therapeutic treatments

scientific article published on 07 April 2020

PET/CT imaging of renal cell carcinoma with (18)F-VM4-037: a phase II pilot study

scientific article published in January 2016

Partial nephrectomy after previous radio frequency ablation: the National Cancer Institute experience

scientific article

Prostate cancer: can multiparametric MR imaging help identify patients who are candidates for active surveillance?

scientific article published on 06 March 2013

Proteasome inhibition disrupts the metabolism of fumarate hydratase- deficient tumors by downregulating p62 and c-Myc

scientific article published on 05 December 2019

Radiofrequency ablation of renal tumors

SDHB-Deficient Cancers: The Role of Mutations That Impair Iron Sulfur Cluster Delivery

scientific article published on January 2016

Salvage partial nephrectomy for hereditary renal cancer: feasibility and outcomes

scientific article published on 13 November 2007

SnapShot: Renal Cell Carcinoma

scientific article published on 01 April 2016

Superiority of 68Ga-DOTATATE over 18F-FDG and anatomic imaging in the detection of succinate dehydrogenase mutation (SDHx )-related pheochromocytoma and paraganglioma in the pediatric population.

scientific article published on 4 December 2017

Targeting ABL1-mediated oxidative stress adaptation in fumarate hydratase-deficient cancer

scientific article

Targeting HIF2α Translation with Tempol in VHL-Deficient Clear Cell Renal Cell Carcinoma ⬇️

scientific article published on November 1, 2012

Targeting loss of the Hippo signaling pathway in NF2-deficient papillary kidney cancers

scientific article published on 10 January 2018

The Cancer Genome Atlas of renal cell carcinoma: findings and clinical implications

scientific article published on 05 July 2019

The glycolytic shift in fumarate-hydratase-deficient kidney cancer lowers AMPK levels, increases anabolic propensities and lowers cellular iron levels

scientific article

The somatic genomic landscape of chromophobe renal cell carcinoma

scientific article (publication date: 8 September 2014)

Tonantzitlolone cytotoxicity toward renal cancer cells is PKCθ- and HSF1-dependent

scientific article published on 20 July 2015

UOK 262 cell line, fumarate hydratase deficient (FH-/FH-) hereditary leiomyomatosis renal cell carcinoma: in vitro and in vivo model of an aberrant energy metabolic pathway in human cancer

scientific article

Use of patient-specific MRI-based prostate mold for validation of multiparametric MRI in localization of prostate cancer

scientific article published on January 2012

Very distal apical prostate tumours: identification on multiparametric MRI at 3 Tesla.

scientific article published on 4 October 2012

Von Hippel-Lindau (VHL) inactivation in sporadic clear cell renal cancer: associations with germline VHL polymorphisms and etiologic risk factors

scientific article

von Hippel-Lindau disease–associated solid microcystic serous adenomas masquerading as pancreatic neuroendocrine neoplasms ⬇️

scientific article published on October 27, 2012

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