List of works - Eriks Rozners

2'-Fluoro RNA shows increased Watson-Crick H-bonding strength and stacking relative to RNA: evidence from NMR and thermodynamic data

scientific article

2-Methoxypyridine as Thymidine Mimic in Watson-Crick Base Pairs of DNA and PNA: Synthesis, Thermal Stability and NMR Structural Studies.

scientific article published on 31 August 2017

A Single Amide Linkage in the Passenger Strand Suppresses Its Activity and Enhances Guide Strand Targeting of siRNAs.

scientific article published on 3 January 2018

Amide linkages mimic phosphates in RNA interactions with proteins and are well tolerated in the guide strand of short interfering RNAs

scientific article published in August 2017

Amide-Modified RNA: Using Protein Backbone to Modulate Function of Short Interfering RNAs

scientific article published on 13 July 2020

Amides are excellent mimics of phosphate internucleoside linkages and are well tolerated in short interfering RNAs

scientific article

Amides as excellent mimics of phosphate linkages in RNA

scientific article

Artificially created nucleic acids and peptides/proteins in chemical biology

scientific article published on 15 January 2013

Asymmetric synthesis of trans-3,4-dialkyl-gamma-butyrolactones via an acyl-Claisen and iodolactonization route

scientific article published on 01 July 2005

Calorimetry of Nucleic Acids

scientific article published on 01 December 2015

Concurrent Hydrogenation of Three Functional Groups Enables Synthesis of C3'-Homologated Nucleoside Amino Acids

scientific article published on 21 July 2017

Correction: Triplex-forming peptide nucleic acid modified with 2-aminopyridine as a new tool for detection of A-to-I editing

scientific article published on 28 October 2016

Cover Feature: Synthetic, Structural, and RNA Binding Studies on 2‐Aminopyridine‐Modified Triplex‐Forming Peptide Nucleic Acids (Chem. Eur. J. 17/2019)

scholarly article

Crystal structure, stability and in vitro RNAi activity of oligoribonucleotides containing the ribo-difluorotoluyl nucleotide: insights into substrate requirements by the human RISC Ago2 enzyme

scientific article

Determination of Nucleic Acid Hydration Using Osmotic Stress ⬇️

scientific article published on December 1, 2010

Discrimination against major groove adducts by Y-family polymerases of the DinB subfamily

scientific article published on 21 June 2013

Effects of non-catalytic, distal amino acid residues on activity of E. coli DinB (DNA polymerase IV).

scientific article

Expanding functionality of RNA: synthesis and properties of RNA containing imidazole modified tandem G-U wobble base pairs

scientific article published on 20 October 2005

FTIR Spectroscopic Studies of Oligonucleotides That Model a Triple-Helical Domain in Self-Splicing Group I Introns ⬇️

scientific article published on 01 December 1997

Fluorescent 2-Aminopyridine Nucleobases for Triplex-Forming Peptide Nucleic Acids

scientific article

Hydration of short DNA, RNA and 2'-OMe oligonucleotides determined by osmotic stressing

scientific article published on 9 January 2004

Identification of tau stem loop RNA stabilizers

scientific article

Improvement of sequence selectivity in triple helical recognition of RNA by phenylalanine-derived PNA.

scientific article published on July 2013

Interplay of Structure, Hydration and Thermal Stability in Formacetal Modified Oligonucleotides: RNA May Tolerate Nonionic Modifications Better than DNA

scientific article

Monomers for preparation of amide linked RNA: Synthesis of C3'-homologated nucleoside amino acids from d-xylose

scientific article published on July 2010

Monomers for preparation of amide-linked RNA: asymmetric synthesis of all four nucleoside 5'-azido 3'-carboxylic acids

scientific article

Nucleobase-Modified PNA Suppresses Translation by Forming a Triple Helix with a Hairpin Structure in mRNA In Vitro and in Cells

scientific article published on 16 October 2015

Nucleobase-Modified Triplex-Forming Peptide Nucleic Acids for Sequence-Specific Recognition of Double-Stranded RNA

scientific article published on 01 January 2020

Oligoribonucleotide analogues containing a mixed backbone of phosphodiester and formacetal internucleoside linkages, together with vicinal 2'-O-methyl groups

scientific article published on 01 March 2007

PNA containing isocytidine nucleobase: synthesis and recognition of double helical RNA.

scientific article published on February 2011

Peptide nucleic acid probe for protein affinity purification based on biotin-streptavidin interaction and peptide nucleic acid strand hybridization

scientific article published on 23 October 2014

RNA-Synthesis Using the H-Phosphonate Approach and an Improved Protecting Group Strategy ⬇️

scholarly article

Recent advances in chemical modification of Peptide nucleic acids

scientific article published on 6 September 2012

Recognition of double-stranded RNA by guanidine-modified peptide nucleic acids

scientific article

Sequence selective recognition of double-stranded RNA at physiologically relevant conditions using PNA-peptide conjugates

scientific article published on 12 June 2013

Sequence selective recognition of double-stranded RNA using triple helix-forming peptide nucleic acids

scientific article published on January 2014

Sequence-selective recognition of double-stranded RNA and enhanced cellular uptake of cationic nucleobase and backbone-modified peptide nucleic acids

scientific article published on 14 October 2016

Sequence-specific recognition of structured RNA by triplex-forming peptide nucleic acids

scientific article published on 27 April 2019

Short peptide nucleic acids bind strongly to homopurine tract of double helical RNA at pH 5.5.

scientific article published on June 2010

Structural Insights into Conformation Differences between DNA/TNA and RNA/TNA Chimeric Duplexes

scientific article published on 27 June 2016

Synthesis and Biological Activity of Short Interfering RNAs Having Several Consecutive Amide Internucleoside Linkages

scientific article published on 17 December 2019

Synthesis and RNA-Binding Properties of Extended Nucleobases for Triplex-Forming Peptide Nucleic Acids

scientific article published on 02 October 2019

Synthesis and properties of RNA analogues having amides as interuridine linkages at selected positions.

scientific article published in October 2003

Synthesis and properties of peptide nucleic acid labeled at the N-terminus with HiLyte Fluor 488 fluorescent dye.

scientific article

Synthesis and properties of triazole-linked RNA.

scientific article

Synthesis of Oligoribonucleotides by the H-Phosphonate Approach Using Base Labile 2′-O-Protecting Groups. V. Recent Progress in Development of the Method

article

Synthesis, biophysical studies and RNA interference activity of RNA having three consecutive amide linkages

scientific article published on February 2014

Synthetic, Structural, and RNA Binding Studies on 2-Aminopyridine-Modified Triplex-Forming Peptide Nucleic Acids

scientific article published on 04 March 2019

Total Synthesis of 3‘,5‘-C-Branched Nucleosides ⬇️

scientific article published on October 16, 2003

Toward amide-linked RNA mimics: total synthesis of 3'-C branched uridine azido acid via an ene-iodolactonization approach

scientific article published on January 2003

Toward amide-modified RNA: synthesis of 3'-aminomethyl-5'-carboxy-3',5'-dideoxy nucleosides

scientific article published on 01 August 2006

Triple helical recognition of pyrimidine inversions in polypurine tracts of RNA by nucleobase-modified PNA.

scientific article

Triple-helical recognition of RNA using 2-aminopyridine-modified PNA at physiologically relevant conditions

scientific article published on 4 November 2012

Triplex-Forming Peptide Nucleic Acids with Extended Backbones

scientific article published on 22 July 2020

Triplex-forming PNA modified with unnatural nucleobases: the role of protonation entropy in RNA binding

scientific article published on 21 November 2016

Triplex-forming peptide nucleic acid modified with 2-aminopyridine as a new tool for detection of A-to-I editing

scientific article published on 9 May 2016

Triplex-forming peptide nucleic acids as emerging ligands to modulate structure and function of complex RNAs

scholarly article published in 2024

Unexpected origins of the enhanced pairing affinity of 2'-fluoro-modified RNA

scientific article

Unique gene-silencing and structural properties of 2'-fluoro-modified siRNAs

scientific article

Using triple-helix-forming Peptide nucleic acids for sequence-selective recognition of double-stranded RNA.

scientific article

List of works by Eriks Rozners

2'-Fluoro RNA shows increased Watson-Crick H-bonding strength and stacking relative to RNA: evidence from NMR and thermodynamic data

2-Methoxypyridine as Thymidine Mimic in Watson-Crick Base Pairs of DNA and PNA: Synthesis, Thermal Stability and NMR Structural Studies.

A Single Amide Linkage in the Passenger Strand Suppresses Its Activity and Enhances Guide Strand Targeting of siRNAs.

Amide linkages mimic phosphates in RNA interactions with proteins and are well tolerated in the guide strand of short interfering RNAs

Amide-Modified RNA: Using Protein Backbone to Modulate Function of Short Interfering RNAs

Amides are excellent mimics of phosphate internucleoside linkages and are well tolerated in short interfering RNAs

Amides as excellent mimics of phosphate linkages in RNA

Artificially created nucleic acids and peptides/proteins in chemical biology

Asymmetric synthesis of trans-3,4-dialkyl-gamma-butyrolactones via an acyl-Claisen and iodolactonization route

Calorimetry of Nucleic Acids

Concurrent Hydrogenation of Three Functional Groups Enables Synthesis of C3'-Homologated Nucleoside Amino Acids

Correction: Triplex-forming peptide nucleic acid modified with 2-aminopyridine as a new tool for detection of A-to-I editing

Cover Feature: Synthetic, Structural, and RNA Binding Studies on 2‐Aminopyridine‐Modified Triplex‐Forming Peptide Nucleic Acids (Chem. Eur. J. 17/2019)

Crystal structure, stability and in vitro RNAi activity of oligoribonucleotides containing the ribo-difluorotoluyl nucleotide: insights into substrate requirements by the human RISC Ago2 enzyme

Determination of Nucleic Acid Hydration Using Osmotic Stress ⬇️

Discrimination against major groove adducts by Y-family polymerases of the DinB subfamily

Effects of non-catalytic, distal amino acid residues on activity of E. coli DinB (DNA polymerase IV).

Expanding functionality of RNA: synthesis and properties of RNA containing imidazole modified tandem G-U wobble base pairs

FTIR Spectroscopic Studies of Oligonucleotides That Model a Triple-Helical Domain in Self-Splicing Group I Introns ⬇️

Fluorescent 2-Aminopyridine Nucleobases for Triplex-Forming Peptide Nucleic Acids

Hydration of short DNA, RNA and 2'-OMe oligonucleotides determined by osmotic stressing

Identification of tau stem loop RNA stabilizers

Improvement of sequence selectivity in triple helical recognition of RNA by phenylalanine-derived PNA.

Interplay of Structure, Hydration and Thermal Stability in Formacetal Modified Oligonucleotides: RNA May Tolerate Nonionic Modifications Better than DNA

Monomers for preparation of amide linked RNA: Synthesis of C3'-homologated nucleoside amino acids from d-xylose

Monomers for preparation of amide-linked RNA: asymmetric synthesis of all four nucleoside 5'-azido 3'-carboxylic acids

Nucleobase-Modified PNA Suppresses Translation by Forming a Triple Helix with a Hairpin Structure in mRNA In Vitro and in Cells

Nucleobase-Modified Triplex-Forming Peptide Nucleic Acids for Sequence-Specific Recognition of Double-Stranded RNA

Oligoribonucleotide analogues containing a mixed backbone of phosphodiester and formacetal internucleoside linkages, together with vicinal 2'-O-methyl groups

PNA containing isocytidine nucleobase: synthesis and recognition of double helical RNA.

Peptide nucleic acid probe for protein affinity purification based on biotin-streptavidin interaction and peptide nucleic acid strand hybridization

RNA-Synthesis Using the H-Phosphonate Approach and an Improved Protecting Group Strategy ⬇️

Recent advances in chemical modification of Peptide nucleic acids

Recognition of double-stranded RNA by guanidine-modified peptide nucleic acids

Sequence selective recognition of double-stranded RNA at physiologically relevant conditions using PNA-peptide conjugates

Sequence selective recognition of double-stranded RNA using triple helix-forming peptide nucleic acids

Sequence-selective recognition of double-stranded RNA and enhanced cellular uptake of cationic nucleobase and backbone-modified peptide nucleic acids

Sequence-specific recognition of structured RNA by triplex-forming peptide nucleic acids

Short peptide nucleic acids bind strongly to homopurine tract of double helical RNA at pH 5.5.

Structural Insights into Conformation Differences between DNA/TNA and RNA/TNA Chimeric Duplexes

Synthesis and Biological Activity of Short Interfering RNAs Having Several Consecutive Amide Internucleoside Linkages

Synthesis and RNA-Binding Properties of Extended Nucleobases for Triplex-Forming Peptide Nucleic Acids

Synthesis and properties of RNA analogues having amides as interuridine linkages at selected positions.

Synthesis and properties of peptide nucleic acid labeled at the N-terminus with HiLyte Fluor 488 fluorescent dye.

Synthesis and properties of triazole-linked RNA.

Synthesis of Oligoribonucleotides by the H-Phosphonate Approach Using Base Labile 2′-O-Protecting Groups. V. Recent Progress in Development of the Method

Synthesis, biophysical studies and RNA interference activity of RNA having three consecutive amide linkages

Synthetic, Structural, and RNA Binding Studies on 2-Aminopyridine-Modified Triplex-Forming Peptide Nucleic Acids

Total Synthesis of 3‘,5‘-C-Branched Nucleosides ⬇️

Toward amide-linked RNA mimics: total synthesis of 3'-C branched uridine azido acid via an ene-iodolactonization approach

Toward amide-modified RNA: synthesis of 3'-aminomethyl-5'-carboxy-3',5'-dideoxy nucleosides

Triple helical recognition of pyrimidine inversions in polypurine tracts of RNA by nucleobase-modified PNA.

Triple-helical recognition of RNA using 2-aminopyridine-modified PNA at physiologically relevant conditions

Triplex-Forming Peptide Nucleic Acids with Extended Backbones

Triplex-forming PNA modified with unnatural nucleobases: the role of protonation entropy in RNA binding

Triplex-forming peptide nucleic acid modified with 2-aminopyridine as a new tool for detection of A-to-I editing

Triplex-forming peptide nucleic acids as emerging ligands to modulate structure and function of complex RNAs

Unexpected origins of the enhanced pairing affinity of 2'-fluoro-modified RNA

Unique gene-silencing and structural properties of 2'-fluoro-modified siRNAs

Using triple-helix-forming Peptide nucleic acids for sequence-selective recognition of double-stranded RNA.