List of works - Nouri Neamati

A nanoscale graphene oxide–peptide biosensor for real-time specific biomarker detection on the cell surface ⬇️

scientific article published on October 9, 2012

A novel phenylcyclohex-1-enecarbothioamide derivative inhibits CXCL8-mediated chemotaxis through selective regulation of CXCR2-mediated signalling

scientific article

A proteomic approach links decreased pyruvate kinase M2 expression to oxaliplatin resistance in patients with colorectal cancer and in human cell lines

scientific article

A symmetric region of the HIV-1 integrase dimerization interface is essential for viral replication

scientific article

Advances toward COVID-19 Therapies Special Issue Call for Papers

scientific article published on 02 December 2020

Allosteric Inhibitor Development Targeting HIV‐1 Integrase ⬇️

scientific article published on January 12, 2011

Blocking interactions between HIV-1 integrase and cellular cofactors: an emerging anti-retroviral strategy

scientific article published on 21 September 2007

COVID-19: Living through Another Pandemic

scientific article published on 10 May 2020

Design and Synthesis of Novel Reactive Oxygen Species Inducers for the Treatment of Pancreatic Ductal Adenocarcinoma.

scientific article published on 12 January 2018

Design of HIV-1 integrase inhibitors targeting the catalytic domain as well as its interaction with LEDGF/p75: A scaffold hopping approach using salicylate and catechol groups ⬇️

scientific article published on June 26, 2011

Design of a novel cyclotide-based CXCR4 antagonist with anti-human immunodeficiency virus (HIV)-1 activity

scientific article

Design of second generation HIV-1 integrase inhibitors

scientific article published on January 2007

Design, Synthesis, and Biological Evaluation of 4-Quinoline Carboxylic Acids as Inhibitors of Dihydroorotate Dehydrogenase

scientific article published on 14 May 2018

Design, Synthesis, and Biological Evaluation of Novel Allosteric Protein Disulfide Isomerase Inhibitors

scientific article published on 02 April 2019

Development of the next generation of HIV-1 integrase inhibitors: Pyrazolone as a novel inhibitor scaffold ⬇️

scientific article published on August 17, 2010

Dipyrimidine-based inhibitors of HIV-1 integrase

scientific article

Discovery of Novel CXCR2 Inhibitors Using Ligand-Based Pharmacophore Models

scientific article published on 8 July 2015

Discovery of a Novel Series of Inhibitors of Lymphoid Tyrosine Phosphatase with Activity in Human T Cells ⬇️

scientific article published on February 22, 2011

Discovery of a small-molecule HIV-1 integrase inhibitor-binding site

scholarly article

Discovery of an orally active small-molecule irreversible inhibitor of protein disulfide isomerase for ovarian cancer treatment

scientific article

Discovery of novel small-molecule inhibitors of human epidermal growth factor receptor-2: combined ligand and target-based approach.

scientific article

Effect of HIV integrase inhibitors on the RAG1/2 recombinase

scientific article

HIV integrase inhibitors with nucleobase scaffolds: discovery of a highly potent anti-HIV agent

scientific article published on January 2006

HIV-1 integrase inhibitors: 2003-2004 update

scientific article

HIV-1 integrase inhibitors: 2005-2006 update

scientific article published on January 2008

HIV-1 integrase inhibitors: an emerging clinical reality

scientific article published on January 2007

In Vivo Activation of the p53 Tumor Suppressor Pathway by an Engineered Cyclotide

scientific article

Inhibition of human immunodeficiency virus type 1 integration by diketo derivatives

scientific article

Integrin Targeted Therapeutics ⬇️

scientific article published on February 17, 2011

Loss of survivin in the prostate epithelium impedes carcinogenesis in a mouse model of prostate adenocarcinoma

scientific article (publication date: 2013)

Mechanisms underlying the cytotoxicity of a novel quinazolinedione-based redox modulator, QD232, in pancreatic cancer cells

scientific article

Mechanistic evaluation and transcriptional signature of a glutathione S-transferase omega 1 inhibitor

scientific article published on 05 October 2016

Mechanistic evaluation of a novel small molecule targeting mitochondria in pancreatic cancer cells

scientific article

New paradigms in drug design and discovery

scientific article

Photoaffinity labeling combined with mass spectrometric approaches as a tool for structural proteomics.

scientific article

Preclinical Evaluation of Novel Triphenylphosphonium Salts with Broad-Spectrum Activity ⬇️

scientific article published on October 4, 2010

Preparation of DNA-Protein Complexes Suitable for Spectroscopic Analysis

scientific article published on January 1, 2003

Purification and specific assays for measuring APE-1 endonuclease activity.

scientific article

Pyrimidine-based compounds modulate CXCR2-mediated signaling and receptor turnover.

scientific article

Raltegravir: The evidence of its therapeutic value in HIV-1 infection ⬇️

scientific article published on June 15, 2010

Rapid parallel synthesis of bioactive folded cyclotides by using a tea-bag approach

scientific article published on 6 February 2015

Ring substituent effects on biological activity of vinyl sulfones as inhibitors of HIV-1

scientific article

Small molecule inhibitors of CXCR4.

scientific article

Small molecule inhibitors of Stat3 signaling pathway.

scientific article published on February 2007

Small molecules anti-HIV therapeutics targeting CXCR4.

scientific article published on January 2008

Small-molecule HIV-1 integrase inhibitors: the 2001-2002 update

scientific article

Small-molecule inhibitors of APE1 DNA repair function: an overview

scientific article published on January 1, 2012

Small-molecule inhibitors of p53-MDM2 interaction: the 2006-2010 update.

scientific article

Structure-Based Design of N-(5-Phenylthiazol-2-yl)acrylamides as Novel and Potent Glutathione S-Transferase Omega 1 Inhibitors

scientific article published on 22 February 2019

Structure-based inhibitor design targeting HIV-1 integrase

scientific article

VprBP has intrinsic kinase activity targeting histone H2A and represses gene transcription

scientific article

Why All the Fuss about Oxidative Phosphorylation (OXPHOS)?

scientific article published on 26 October 2020

List of works by Nouri Neamati

A nanoscale graphene oxide–peptide biosensor for real-time specific biomarker detection on the cell surface ⬇️

A novel phenylcyclohex-1-enecarbothioamide derivative inhibits CXCL8-mediated chemotaxis through selective regulation of CXCR2-mediated signalling

A proteomic approach links decreased pyruvate kinase M2 expression to oxaliplatin resistance in patients with colorectal cancer and in human cell lines

A symmetric region of the HIV-1 integrase dimerization interface is essential for viral replication

Advances toward COVID-19 Therapies Special Issue Call for Papers

Allosteric Inhibitor Development Targeting HIV‐1 Integrase ⬇️

Blocking interactions between HIV-1 integrase and cellular cofactors: an emerging anti-retroviral strategy

COVID-19: Living through Another Pandemic

Design and Synthesis of Novel Reactive Oxygen Species Inducers for the Treatment of Pancreatic Ductal Adenocarcinoma.

Design of HIV-1 integrase inhibitors targeting the catalytic domain as well as its interaction with LEDGF/p75: A scaffold hopping approach using salicylate and catechol groups ⬇️

Design of a novel cyclotide-based CXCR4 antagonist with anti-human immunodeficiency virus (HIV)-1 activity

Design of second generation HIV-1 integrase inhibitors

Design, Synthesis, and Biological Evaluation of 4-Quinoline Carboxylic Acids as Inhibitors of Dihydroorotate Dehydrogenase

Design, Synthesis, and Biological Evaluation of Novel Allosteric Protein Disulfide Isomerase Inhibitors

Development of the next generation of HIV-1 integrase inhibitors: Pyrazolone as a novel inhibitor scaffold ⬇️

Dipyrimidine-based inhibitors of HIV-1 integrase

Discovery of Novel CXCR2 Inhibitors Using Ligand-Based Pharmacophore Models

Discovery of a Novel Series of Inhibitors of Lymphoid Tyrosine Phosphatase with Activity in Human T Cells ⬇️

Discovery of a small-molecule HIV-1 integrase inhibitor-binding site

Discovery of an orally active small-molecule irreversible inhibitor of protein disulfide isomerase for ovarian cancer treatment

Discovery of novel small-molecule inhibitors of human epidermal growth factor receptor-2: combined ligand and target-based approach.

Effect of HIV integrase inhibitors on the RAG1/2 recombinase

HIV integrase inhibitors with nucleobase scaffolds: discovery of a highly potent anti-HIV agent

HIV-1 integrase inhibitors: 2003-2004 update

HIV-1 integrase inhibitors: 2005-2006 update

HIV-1 integrase inhibitors: an emerging clinical reality

In Vivo Activation of the p53 Tumor Suppressor Pathway by an Engineered Cyclotide

Inhibition of human immunodeficiency virus type 1 integration by diketo derivatives

Integrin Targeted Therapeutics ⬇️

Loss of survivin in the prostate epithelium impedes carcinogenesis in a mouse model of prostate adenocarcinoma

Mechanisms underlying the cytotoxicity of a novel quinazolinedione-based redox modulator, QD232, in pancreatic cancer cells

Mechanistic evaluation and transcriptional signature of a glutathione S-transferase omega 1 inhibitor

Mechanistic evaluation of a novel small molecule targeting mitochondria in pancreatic cancer cells

New paradigms in drug design and discovery

Photoaffinity labeling combined with mass spectrometric approaches as a tool for structural proteomics.

Preclinical Evaluation of Novel Triphenylphosphonium Salts with Broad-Spectrum Activity ⬇️

Preparation of DNA-Protein Complexes Suitable for Spectroscopic Analysis

Purification and specific assays for measuring APE-1 endonuclease activity.

Pyrimidine-based compounds modulate CXCR2-mediated signaling and receptor turnover.

Raltegravir: The evidence of its therapeutic value in HIV-1 infection ⬇️

Rapid parallel synthesis of bioactive folded cyclotides by using a tea-bag approach

Ring substituent effects on biological activity of vinyl sulfones as inhibitors of HIV-1

Small molecule inhibitors of CXCR4.

Small molecule inhibitors of Stat3 signaling pathway.

Small molecules anti-HIV therapeutics targeting CXCR4.

Small-molecule HIV-1 integrase inhibitors: the 2001-2002 update

Small-molecule inhibitors of APE1 DNA repair function: an overview

Small-molecule inhibitors of p53-MDM2 interaction: the 2006-2010 update.

Structure-Based Design of N-(5-Phenylthiazol-2-yl)acrylamides as Novel and Potent Glutathione S-Transferase Omega 1 Inhibitors

Structure-based inhibitor design targeting HIV-1 integrase

VprBP has intrinsic kinase activity targeting histone H2A and represses gene transcription

Why All the Fuss about Oxidative Phosphorylation (OXPHOS)?