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List of works by Rajesh Agarwal

Angiopreventive efficacy of pure flavonolignans from milk thistle extract against prostate cancer: targeting VEGF-VEGFR signaling

scientific article

Anti-Cancer Efficacy of Silybin Derivatives - A Structure-Activity Relationship ⬇️

scientific article published on March 28, 2013

Antimetastatic efficacy of silibinin: molecular mechanisms and therapeutic potential against cancer

scientific article published on September 2010

Asiatic Acid Inhibits Pro-Angiogenic Effects of VEGF and Human Gliomas in Endothelial Cell Culture Models ⬇️

scientific article published on August 3, 2011

Asiatic acid induces endoplasmic reticulum stress and apoptotic death in glioblastoma multiforme cells both in vitro and in vivo

scientific article published on 22 September 2014

Beneficial effects of the naturally occurring flavonoid silibinin on the prostate cancer microenvironment: role of monocyte chemotactic protein-1 and immune cell recruitment

scientific article published on 2 April 2016

Bitter melon juice activates cellular energy sensor AMP-activated protein kinase causing apoptotic death of human pancreatic carcinoma cells ⬇️

scientific article published on 08 March 2013

Bitter melon juice exerts its efficacy against pancreatic cancer via targeting both bulk and cancer stem cells.

scientific article published on 4 May 2018

Bitter melon juice intake with gemcitabine intervention circumvents resistance to gemcitabine in pancreatic patient-derived xenograft tumors

scientific article published on 20 August 2020

Bitter melon juice targets molecular mechanisms underlying gemcitabine resistance in pancreatic cancer cells

scientific article

Chemopreventive efficacy of silymarin in skin and prostate cancer

scientific article published on June 2007

Chemopreventive opportunities to control basal cell carcinoma: Current perspectives

scientific article published on 05 June 2015

Differential effect of grape seed extract and its active constituent procyanidin B2 3,3″-di-O-gallate against prostate cancer stem cells

scientific article published on 03 March 2019

Exosomes secreted by prostate cancer cells under hypoxia promote matrix metalloproteinases activity at pre-metastatic niches

scientific article published on 14 January 2020

Exosomes secreted under hypoxia enhance invasiveness and stemness of prostate cancer cells by targeting adherens junction molecules

scientific article

Generation of reactive oxygen species by grape seed extract causes irreparable DNA damage leading to G2/M arrest and apoptosis selectively in head and neck squamous cell carcinoma cells

scientific article published on 19 January 2012

Grape seed extract and resveratrol prevent 4-nitroquinoline 1-oxide induced oral tumorigenesis in mice by modulating AMPK activation and associated biological responses

scientific article

Grape seed extract targets mitochondrial electron transport chain complex III and induces oxidative and metabolic stress leading to cytoprotective autophagy and apoptotic death in human head and neck cancer cells

scientific article published on 31 December 2014

Graviola inhibits hypoxia-induced NADPH oxidase activity in prostate cancer cells reducing their proliferation and clonogenicity

scientific article published on 16 March 2016

Hypoxia induces triglycerides accumulation in prostate cancer cells and extracellular vesicles supporting growth and invasiveness following reoxygenation

scientific article

Identifying the differential effects of silymarin constituents on cell growth and cell cycle regulatory molecules in human prostate cancer cells.

scientific article

Inhibition of Lipid Oxidation Increases Glucose Metabolism and Enhances 2-Deoxy-2-[(18)F]Fluoro-D-Glucose Uptake in Prostate Cancer Mouse Xenografts

scientific article

Interleukin-1beta-induced iNOS expression in human lung carcinoma A549 cells: involvement of STAT and MAPK pathways

scientific article published on November 1, 2011

Isosilybin A induces apoptosis in human prostate cancer cells via targeting Akt, NF-κB, and androgen receptor signaling

scientific article published on October 2010

Isosilybin B and isosilybin A inhibit growth, induce G1 arrest and cause apoptosis in human prostate cancer LNCaP and 22Rv1 cells.

scientific article published on 26 March 2007

Kava, a tonic for relieving the irrational development of natural preventive agents

scientific article

Metformin suppresses growth of human head and neck squamous cell carcinoma via global inhibition of protein translation ⬇️

scientific article published on April 1, 2012

Molecular mechanisms of silibinin-mediated cancer chemoprevention with major emphasis on prostate cancer

scientific article

New combination therapies with cell-cycle agents

scientific article published on June 2008

Nintedanib inhibits growth of human prostate carcinoma cells by modulating both cell cycle and angiogenesis regulators.

scientific article

Phylogenetic and chemical diversity of fungal endophytes isolated from Silybum marianum (L) Gaertn. (milk thistle)

scientific article published on January 2015

Procyanidin B2 3,3″-di-O-gallate inhibits endothelial cells growth and motility by targeting VEGFR2 and integrin signaling pathways

scientific article published on January 2015

Role of E-cadherin in Antimigratory and Antiinvasive Efficacy of Silibinin in Prostate Cancer Cells ⬇️

scientific article published on May 5, 2011

SNAI1 is critical for the aggressiveness of prostate cancer cells with low E-cadherin

scientific article published on 24 February 2014

Silibinin Preferentially Radiosensitizes Prostate Cancer by Inhibiting DNA Repair Signaling

scientific article

Silibinin and its 2,3-dehydro-derivative inhibit basal cell carcinoma growth via suppression of mitogenic signaling and transcription factors activation.

scientific article published on 9 December 2014

Silibinin enhances the repair of ultraviolet B-induced DNA damage by activating p53-dependent nucleotide excision repair mechanism in human dermal fibroblasts

scientific article published on 3 October 2015

Silibinin exerts sustained growth suppressive effect against human colon carcinoma SW480 xenograft by targeting multiple signaling molecules

scientific article

Silibinin inhibits aberrant lipid metabolism, proliferation and emergence of androgen-independence in prostate cancer cells via primarily targeting the sterol response element binding protein 1.

scientific article published on October 2014

Silibinin inhibits cytokine-induced signaling cascades and down-regulates inducible nitric oxide synthase in human lung carcinoma A549 cells

scientific article published on July 2008

Silibinin inhibits fibronectin induced motility, invasiveness and survival in human prostate carcinoma PC3 cells via targeting integrin signaling

scientific article published on October 2014

Silibinin inhibits prostate cancer cells- and RANKL-induced osteoclastogenesis by targeting NFATc1, NF-κB, and AP-1 activation in RAW264.7 cells

scientific article published on 31 October 2012

Silibinin inhibits ultraviolet B radiation-induced DNA-damage and apoptosis by enhancing interleukin-12 expression in JB6 cells and SKH-1 hairless mouse skin ⬇️

scientific article published on January 28, 2013

Silibinin inhibits ultraviolet B radiation-induced mast cells recruitment and bone morphogenetic protein 2 expression in the skin at early stages in Ptch(+/-) mouse model of basal cell carcinoma

scientific article published on 25 March 2019

Silibinin prevents prostate cancer cell-mediated differentiation of naïve fibroblasts into cancer-associated fibroblast phenotype by targeting TGF β2.

scientific article published on 24 February 2014

Silibinin prevents ultraviolet B radiation-induced epidermal damages in JB6 cells and mouse skin in a p53-GADD45α-dependent manner ⬇️

scientific article published on December 12, 2011

Silibinin suppresses growth and induces apoptotic death of human colorectal carcinoma LoVo cells in culture and tumor xenograft

scientific article published on 28 July 2009

Silibinin suppresses growth of human prostate carcinoma PC-3 orthotopic xenograft via activation of extracellular signal-regulated kinase 1/2 and inhibition of signal transducers and activators of transcription signaling

scientific article

Stage-specific inhibitory effects and associated mechanisms of silibinin on tumor progression and metastasis in transgenic adenocarcinoma of the mouse prostate model

scientific article published on August 2008

Talarolutins A-D: Meroterpenoids from an endophytic fungal isolate of Talaromyces minioluteus. ⬇️

scientific article published on 2 April 2016

Targeting tumor microenvironment with silibinin: promise and potential for a translational cancer chemopreventive strategy

scientific article published on June 2013

The strategies to control prostate cancer by chemoprevention approaches

scientific article published on 02 January 2014

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