List of works - Jeremy M Simon

A conditional mouse expressing an activating mutation in NRF2 displays hyperplasia of the upper gastrointestinal tract and decreased white adipose tissue

scientific article published on 03 July 2020

A myelin-related transcriptomic profile is shared by Pitt-Hopkins syndrome models and human autism spectrum disorder

scientific article published on 03 February 2020

An oncogenic Ezh2 mutation induces tumors through global redistribution of histone 3 lysine 27 trimethylation.

scientific article published on 2 May 2016

Cas9 gene therapy for Angelman syndrome traps Ube3a-ATS long non-coding RNA

scientific article published on 21 October 2020

Chd8 haploinsufficiency impairs early brain development and protein homeostasis later in life

scientific article published on 05 October 2020

Deletion of Topoisomerase 1 in excitatory neurons causes genomic instability and early onset neurodegeneration

scientific article published on 23 April 2020

Enhanced Nociception in Angelman Syndrome Model Mice

scientific article

High-throughput screening and classification of chemicals and their effects on neuronal gene expression using RASL-seq

article

Identification of BBOX1 as a Therapeutic Target in Triple-Negative Breast Cancer

scientific article published on 20 July 2020

Identification of chemicals that mimic transcriptional changes associated with autism, brain aging and neurodegeneration.

scientific article published on 31 March 2016

Integrative QTL analysis of gene expression and chromatin accessibility identifies multi-tissue patterns of genetic regulation

scientific article published on 21 January 2020

Molecular classification of Crohn's disease reveals two clinically relevant subtypes.

scientific article published on 14 October 2016

PBRM1 Inactivation Promotes Upregulation of Human Endogenous Retroviruses in a HIF-Dependent Manner

publication published on 01 March 2022

Prolyl hydroxylase substrate adenylosuccinate lyase is an oncogenic driver in triple negative breast cancer

scientific article published on 15 November 2019

Rescue of behavioral and electrophysiological phenotypes in a Pitt-Hopkins syndrome mouse model by genetic restoration of <i>Tcf4</i> expression

scientific article published on 10 May 2022

Single-cell transcriptomic analysis of mouse neocortical development

scientific article published in Nature Communications

Transcriptomic analyses of gastrulation-stage mouse embryos with differential susceptibility to alcohol

scientific article published on 27 May 2021

USP37 promotes deubiquitination of HIF2α in kidney cancer

scientific article published on 27 May 2020

VHL substrate transcription factor ZHX2 as an oncogenic driver in clear cell renal cell carcinoma