List of works - Carol Ann Remme

'Mature' resting membrane potentials in human-induced pluripotent stem cell-derived cardiomyocytes: fact or artefact?

scientific article published on 03 October 2019

A Heterozygous Deletion Mutation in the Cardiac Sodium Channel Gene SCN5A with Loss- and Gain-of-Function Characteristics Manifests as Isolated Conduction Disease, without Signs of Brugada or Long QT Syndrome ⬇️

scientific article published on June 28, 2013

Animal models and animal-free innovations for cardiovascular research: current status and routes to be explored. Consensus document of the ESC Working Group on Myocardial Function and the ESC Working Group on Cellular Biology of the Heart

scientific article published in 2022

CDNA arrays: the ups and downs

scientific article published on 01 March 2001

Cardiac sodium channelopathy associated with SCN5A mutations: electrophysiological, molecular and genetic aspects ⬇️

scientific article published on September 1, 2013

Cardiomyocytes derived from pluripotent stem cells recapitulate electrophysiological characteristics of an overlap syndrome of cardiac sodium channel disease

scientific article published on 30 May 2012

Common variants at SCN5A-SCN10A and HEY2 are associated with Brugada syndrome, a rare disease with high risk of sudden cardiac death

scientific article

Coxsackie and adenovirus receptor is a modifier of cardiac conduction and arrhythmia vulnerability in the setting of myocardial ischemia

scientific article

Early repolarization in mice causes overestimation of ventricular activation time by the QRS duration

scientific article published on 20 September 2012

Erratum: Common variants at SCN5A-SCN10A and HEY2 are associated with Brugada syndrome, a rare disease with high risk of sudden cardiac death

scholarly article published in Nature Genetics

Functional Consequences of the SCN5A-p.Y1977N Mutation within the PY Ubiquitylation Motif: Discrepancy between HEK293 Cells and Transgenic Mice

scientific article published on 11 October 2019

Genetically determined differences in sodium current characteristics modulate conduction disease severity in mice with cardiac sodium channelopathy

scientific article published on 30 April 2009

Getting to the heart of rhythm: a century of progress

scientific article published in 2022

Human iPSC-Derived Cardiomyocytes for Investigation of Disease Mechanisms and Therapeutic Strategies in Inherited Arrhythmia Syndromes: Strengths and Limitations.

scientific article

Intercalated disc abnormalities, reduced Na(+) current density, and conduction slowing in desmoglein-2 mutant mice prior to cardiomyopathic changes

scientific article

Late Sodium Current Inhibition in Acquired and Inherited Ventricular (dys)function and Arrhythmias ⬇️

scientific article published on February 1, 2013

Neurokinin-3 receptor activation selectively prolongs atrial refractoriness by inhibition of a background K channel

scientific article published in Nature Communications

Overlap syndrome of cardiac sodium channel disease in mice carrying the equivalent mutation of human SCN5A-1795insD

scientific article

Reduced sodium channel function unmasks residual embryonic slow conduction in the adult right ventricular outflow tract.

scientific article published on 9 May 2013

The sodium channel NaV 1.5 impacts on early murine embryonic cardiac development, structure, and function in a non-electrogenic manner

scientific article published on 09 May 2020

Transgenic models of cardiac arrhythmias and sudden death ⬇️

scientific article published on March 28, 2013

Zebrafish: a novel research tool for cardiac (patho)electrophysiology and ion channel disorders ⬇️

scientific article published on July 10, 2012

List of works by Carol Ann Remme

'Mature' resting membrane potentials in human-induced pluripotent stem cell-derived cardiomyocytes: fact or artefact?

A Heterozygous Deletion Mutation in the Cardiac Sodium Channel Gene SCN5A with Loss- and Gain-of-Function Characteristics Manifests as Isolated Conduction Disease, without Signs of Brugada or Long QT Syndrome ⬇️

Animal models and animal-free innovations for cardiovascular research: current status and routes to be explored. Consensus document of the ESC Working Group on Myocardial Function and the ESC Working Group on Cellular Biology of the Heart

CDNA arrays: the ups and downs

Cardiac sodium channelopathy associated with SCN5A mutations: electrophysiological, molecular and genetic aspects ⬇️

Cardiomyocytes derived from pluripotent stem cells recapitulate electrophysiological characteristics of an overlap syndrome of cardiac sodium channel disease

Common variants at SCN5A-SCN10A and HEY2 are associated with Brugada syndrome, a rare disease with high risk of sudden cardiac death

Coxsackie and adenovirus receptor is a modifier of cardiac conduction and arrhythmia vulnerability in the setting of myocardial ischemia

Early repolarization in mice causes overestimation of ventricular activation time by the QRS duration

Erratum: Common variants at SCN5A-SCN10A and HEY2 are associated with Brugada syndrome, a rare disease with high risk of sudden cardiac death

Functional Consequences of the SCN5A-p.Y1977N Mutation within the PY Ubiquitylation Motif: Discrepancy between HEK293 Cells and Transgenic Mice

Genetically determined differences in sodium current characteristics modulate conduction disease severity in mice with cardiac sodium channelopathy

Getting to the heart of rhythm: a century of progress

Human iPSC-Derived Cardiomyocytes for Investigation of Disease Mechanisms and Therapeutic Strategies in Inherited Arrhythmia Syndromes: Strengths and Limitations.

Intercalated disc abnormalities, reduced Na(+) current density, and conduction slowing in desmoglein-2 mutant mice prior to cardiomyopathic changes

Late Sodium Current Inhibition in Acquired and Inherited Ventricular (dys)function and Arrhythmias ⬇️

Neurokinin-3 receptor activation selectively prolongs atrial refractoriness by inhibition of a background K channel

Overlap syndrome of cardiac sodium channel disease in mice carrying the equivalent mutation of human SCN5A-1795insD

Reduced sodium channel function unmasks residual embryonic slow conduction in the adult right ventricular outflow tract.

The sodium channel NaV 1.5 impacts on early murine embryonic cardiac development, structure, and function in a non-electrogenic manner

Transgenic models of cardiac arrhythmias and sudden death ⬇️

Zebrafish: a novel research tool for cardiac (patho)electrophysiology and ion channel disorders ⬇️