Search filters

List of works by Vidar M Steen

1q21.1 distal copy number variants are associated with cerebral and cognitive alterations in humans

scientific article published on 22 March 2021

A genetic association study of CSMD1 and CSMD2 with cognitive function

scientific article published on 24 November 2016

A genetic deconstruction of neurocognitive traits in schizophrenia and bipolar disorder

scientific article

A genome-wide association study of anorexia nervosa

scientific article

A human myo-inositol monophosphatase gene (IMPA2) localized in a putative susceptibility region for bipolar disorder on chromosome 18p11.2: genomic structure and polymorphism screening in manic-depressive patients

scientific article

A possible association between schizophrenia and GRIK3 polymorphisms in a multicenter sample of Scandinavian origin (SCOPE).

scientific article published on 20 November 2008

A retroviral element in the human CYP2D gene cluster.

scientific article published in August 1996

A tyrosine kinase-activating variant Asn666Ser in PDGFRB causes a progeria-like condition in the severe end of Penttinen syndrome

scientific article published on 20 December 2018

Acute clozapine exposure in vivo induces lipid accumulation and marked sequential changes in the expression of SREBP, PPAR, and LXR target genes in rat liver

scientific article

Acute effects of orexigenic antipsychotic drugs on lipid and carbohydrate metabolism in rat.

scientific article published on 12 July 2011

Amisulpride, aripiprazole, and olanzapine in patients with schizophrenia-spectrum disorders (BeSt InTro): a pragmatic, rater-blind, semi-randomised trial

scientific article published on 01 November 2020

An 8.9 Mb 19p13 duplication associated with precocious puberty and a sporadic 3.9 Mb 2q23.3q24.1 deletion containing NR4A2 in mentally retarded members of a family with an intrachromosomal 19p-into-19q between-arm insertion

scientific article

Analysis of differentially methylated regions in great apes and extinct hominids provides support for the evolutionary hypothesis of schizophrenia

scientific article published on 11 December 2018

Analysis of shared heritability in common disorders of the brain

scientific article published on 21 June 2018

Analysis of the joint effect of SNPs to identify independent loci and allelic heterogeneity in schizophrenia GWAS data

scientific article

Antidepressant drugs activate SREBP and up-regulate cholesterol and fatty acid biosynthesis in human glial cells

scientific article published on December 2005

Antipsychotic drugs activate SREBP-regulated expression of lipid biosynthetic genes in cultured human glioma cells: a novel mechanism of action?

scientific article

Antipsychotic-induced increase in lipid biosynthesis: activation through inhibition? ⬇️

scientific article published on December 7, 2012

Antipsychotic-induced metabolic effects in the female rat: Direct comparison between long-acting injections of risperidone and olanzapine

scientific article published on 16 September 2015

Array-CGH fine mapping of minor and cryptic HR-CGH detected genomic imbalances in 80 out of 590 patients with abnormal development

scientific article published on 19 February 2009

Array-CGH fine mapping of minor and cryptic HR-CGH detected genomic imbalances in 80 out of 590 patients with abnormal development

scientific article published on 7 May 2008

Association analysis of schizophrenia on 18 genes involved in neuronal migration: MDGA1 as a new susceptibility gene

scientific article published in October 2008

Association between blood carisoprodol:meprobamate concentration ratios and CYP2C19 genotype in carisoprodol-drugged drivers: decreased metabolic capacity in heterozygous CYP2C19*1/CYP2C19*2 subjects?

scientific article published in July 2003

Association between leptin levels and severity of suicidal behaviour in schizophrenia spectrum disorders

scientific article published on 18 March 2019

Association between olanzapine treatment and brain cortical thickness and gray/white matter contrast is moderated by cholesterol in psychotic disorders

scientific article published on 29 October 2018

Association between serum lipid levels, osteoprotegerin and depressive symptomatology in psychotic disorders

scientific article published on 02 May 2018

Association between the insulin-induced gene 2 (INSIG2) and weight gain in a German sample of antipsychotic-treated schizophrenic patients: perturbation of SREBP-controlled lipogenesis in drug-related metabolic adverse effects?

scientific article

Association of Copy Number Variation of the 15q11.2 BP1-BP2 Region With Cortical and Subcortical Morphology and Cognition

scientific article published on 30 October 2019

Association of MCTP2 gene variants with schizophrenia in three independent samples of Scandinavian origin (SCOPE).

scientific article

Association study of PDE4B gene variants in Scandinavian schizophrenia and bipolar disorder multicenter case-control samples

scientific article

Association study of energy homeostasis genes and antipsychotic-induced weight gain in patients with schizophrenia

Associations between C-reactive protein levels and cognition during the first 6 months after acute psychosis

scientific article

Associations between cod liver oil use and symptoms of depression: the Hordaland Health Study

scientific article published on 19 December 2006

Associations between tamoxifen, estrogens, and FSH serum levels during steady state tamoxifen treatment of postmenopausal women with breast cancer

scientific article

Attenuated Notch signaling in schizophrenia and bipolar disorder

scientific article published on 28 March 2018

Auditory hallucinations in schizophrenia: the role of cognitive, brain structural and genetic disturbances in the left temporal lobe

scientific article published in January 2007

Author Correction: Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function ⬇️

scientific article published on 01 May 2019

B56δ-related protein phosphatase 2A dysfunction identified in patients with intellectual disability.

scientific article

BRCA Testing by Single-Molecule Molecular Inversion Probes

scientific article

BRCA1/2 testing in newly diagnosed breast and ovarian cancer patients without prior genetic counselling: the DNA-BONus study.

scientific article published on 9 September 2015

Brain scans from 21,297 individuals reveal the genetic architecture of hippocampal subfield volumes

article by Dennis van der Meer et al published 2 October 2018 in Molecular Psychiatry

Breastfeeding during maternal antidepressant treatment with serotonin reuptake inhibitors: infant exposure, clinical symptoms, and cytochrome p450 genotypes.

scientific article published in September 2004

CYP2D6 multiallelism

scientific article published on 01 January 1996

Candidate gene analysis of the human natural killer-1 carbohydrate pathway and perineuronal nets in schizophrenia: B3GAT2 is associated with disease risk and cortical surface area

scientific article

Characterization and PCR-based detection of two different hybrid CYP2D7P/CYP2D6 alleles associated with the poor metabolizer phenotype

scientific article published on 01 August 1996

Characterization of the 16+9 kb and 30+9 kb CYP2D6 XbaI haplotypes

scientific article published on April 1997

Common brain disorders are associated with heritable patterns of apparent aging of the brain

scientific article published on 24 September 2019

Common genetic variants influence human subcortical brain structures

scientific article

Common variants in the ARC gene are not associated with cognitive abilities

scientific article

Comparison of nucleic acid targets prepared from total RNA or poly(A) RNA for DNA oligonucleotide microarray hybridization

scientific article published on 18 March 2007

Comparison of three variant callers for human whole genome sequencing

scientific article published in Scientific Reports

Conservation of Distinct Genetically-Mediated Human Cortical Pattern

scientific article

Constructing the Immune Signature of Schizophrenia for Clinical Use and Research; An Integrative Review Translating Descriptives Into Diagnostics

Correction: Dose response of the 16p11.2 distal copy number variant on intracranial volume and basal ganglia

scientific article published on 01 March 2020

DCLK1 variants are associated across schizophrenia and attention deficit/hyperactivity disorder

scientific article

Detection of the poor metabolizer-associated CYP2D6(D) gene deletion allele by long-PCR technology

article

Dopamine D3-receptor gene variant and susceptibility to tardive dyskinesia in schizophrenic patients

scientific article

Drug-induced activation of SREBP-controlled lipogenic gene expression in CNS-related cell lines: marked differences between various antipsychotic drugs

scientific article

Duplicated Enhancer Region Increases Expression of CTSB and Segregates with Keratolytic Winter Erythema in South African and Norwegian Families.

scientific article published on 26 April 2017

Effects of CYP2D6 and SULT1A1 genotypes including SULT1A1 gene copy number on tamoxifen metabolism

scientific article published on 18 October 2007

Evidence for tight metabolic control of the receptor-activated polyphosphoinositide cycle in human platelets

scientific article

Evidence that chlorpromazine and prostaglandin E1 but not neomycin interfere with the inositol phospholipid metabolism in intact human platelets

scientific article published on May 1990

Examination of IMPA1 and IMPA2 genes in manic-depressive patients: association between IMPA2 promoter polymorphisms and bipolar disorder

scientific article

Exploring lithium's transcriptional mechanisms of action in bipolar disorder: a multi-step study

scientific article published on 25 October 2019

Exploring the Wnt signaling pathway in schizophrenia and bipolar disorder

scientific article published on 6 March 2018

Expression of TCN1 in Blood is Negatively Associated with Verbal Declarative Memory Performance

scientific article published in Scientific Reports

F22. DYSLIPIDEMIA AND INFLAMMATORY MARKERS IN RELATION TO CLINICAL SYMPTOMATOLOGY IN PSYCHOTIC DISORDERS.

scientific article

F5. Brain Disorders are Associated With Increased Brain Age

GWAS meta-analysis (N=279,930) identifies new genes and functional links to intelligence

article

GWAS meta-analysis reveals novel loci and genetic correlates for general cognitive function: a report from the COGENT consortium

scientific article published on 12 September 2017

GWAS meta-analysis reveals novel loci and genetic correlates for general cognitive function: a report from the COGENT consortium.

scientific article published on 17 January 2017

GWAS-based pathway analysis differentiates between fluid and crystallized intelligence.

scientific article

Gain-of-function mutations in the mechanically activated ion channel PIEZO2 cause a subtype of Distal Arthrogryposis

scientific article

Gene expression in the rat brain: High similarity but unique differences between frontomedial-, temporal- and occipital cortex ⬇️

scientific article published on January 26, 2011

Gene expression profiles in rat brain disclose CNS signature genes and regional patterns of functional specialisation

scientific article

Gene variants associated with schizophrenia in a Norwegian genome-wide study are replicated in a large European cohort

scientific journal article

Gene-based analysis of regionally enriched cortical genes in GWAS data sets of cognitive traits and psychiatric disorders

scientific article

Genetic Architecture of Subcortical Brain Structures in Over 40,000 Individuals Worldwide

scholarly article published 28 August 2017

Genetic architecture of cognitive traits

scientific article published on 08 March 2014

Genetic architecture of subcortical brain structures in 38,851 individuals

scientific article published on 21 October 2019

Genetic basis of a cognitive complexity metric

scientific article

Genetic contributions to variation in general cognitive function: a meta-analysis of genome-wide association studies in the CHARGE consortium (N=53949).

scientific article

Genetic control of variability in subcortical and intracranial volumes

Genetic control of variability in subcortical and intracranial volumes

scientific article published on 11 February 2020

Genetic evidence for a role of the SREBP transcription system and lipid biosynthesis in schizophrenia and antipsychotic treatment

scientific article

Genetic variation in 117 myelination-related genes in schizophrenia: Replication of association to lipid biosynthesis genes

scientific article published in Scientific Reports

Genetics of brain age suggest an overlap with common brain disorders

article

Genetics of structural connectivity and information processing in the brain

scientific article published on 6 February 2016

Genome-Wide Association Study Reveals First Locus for Anorexia Nervosa and Metabolic Correlations

scholarly article

Genome-wide association meta-analysis in 269,867 individuals identifies new genetic and functional links to intelligence

article

Genome-wide association studies establish that human intelligence is highly heritable and polygenic

scientific article

Genome-wide association study identifies genetic loci associated with body mass index and high density lipoprotein-cholesterol levels during psychopharmacological treatment - a cross-sectional naturalistic study

scientific article

Genome-wide autozygosity is associated with lower general cognitive ability

scientific article published on 22 September 2015

Genomic Structure and Chromosomal Localization of a Humanmyo-Inositol Monophosphatase Gene (IMPA) ⬇️

scientific article published on October 1, 1997

Genomic structure and sequence analysis of a human inositol polyphosphate 1-phosphatase gene (INPP1)

scientific article (publication date: August 1999)

Global gene expression profiling of human osteosarcomas reveals metastasis-associated chemokine pattern

scientific article published on 28 February 2012

Homologous unequal cross-over involving a 2.8 kb direct repeat as a mechanism for the generation of allelic variants of human cytochrome P450 CYP2D6 gene

scientific article published in December 1995

Homozygosity for the Gly-9 variant of the dopamine D3 receptor and risk for tardive dyskinesia in schizophrenic patients.

scientific article published on March 2000

Human cognitive ability is influenced by genetic variation in components of postsynaptic signalling complexes assembled by NMDA receptors and MAGUK proteins.

scientific article published on 07 January 2014

Hyperoxia retards growth and induces apoptosis and loss of glands and blood vessels in DMBA-induced rat mammary tumors

scientific article

Identification of Gene Loci That Overlap Between Schizophrenia and Educational Attainment

scientific article published on 23 June 2016

Identification of common variants associated with human hippocampal and intracranial volumes

scientific article published on 15 April 2012

Identification of genes co-upregulated with Arc during BDNF-induced long-term potentiation in adult rat dentate gyrus in vivo

scientific article published in March 2006

Identification of pleiotropy at the gene level between psychiatric disorders and related traits

scientific article published in 2021

Imaging and cognitive genetics: the Norwegian Cognitive NeuroGenetics sample

scientific article published in June 2012

Improvement in verbal learning over the first year of antipsychotic treatment is associated with serum HDL levels in a cohort of first episode psychosis patients

scientific article published on 27 April 2019

Incident users of antipsychotic agents and future use of cholesterol-lowering drugs: an observational, pharmacoepidemiologic study

scientific article published on January 2015

Increase in serum HDL level is associated with less negative symptoms after one year of antipsychotic treatment in first-episode psychosis

scientific article published on 9 November 2017

Increased expression of lipid biosynthesis genes in peripheral blood cells of olanzapine-treated patients

scientific article

Independent evidence for an association between general cognitive ability and a genetic locus for educational attainment

scientific article published on 7 May 2015

Inhibition of ADP-induced responses in human platelets by agents elevating the cyclic AMP level: comparison of aggregation and shape change

scientific article published on December 29, 1984

Is pharmacogenetic CYP2D6 testing useful? ⬇️

scientific article published on November 18, 2010

LOC689986, a unique gene showing specific expression in restricted areas of the rodent neocortex

scientific article (publication date: 11 July 2013)

Lack of Ovarian Secretions Reverts the Anabolic Action of Olanzapine in Female Rats

scientific article published on 14 August 2017

Lack of association of the rs1344706 ZNF804A variant with cognitive functions and DTI indices of white matter microstructure in two independent healthy populations

scientific article

Lack of genetic variation in the coding region of the myo-inositol monophosphatase gene in lithium-treated patients with manic depressive illness.

scientific article published in February 1996

Large-Scale Cognitive GWAS Meta-Analysis Reveals Tissue-Specific Neural Expression and Potential Nootropic Drug Targets

scientific article

Large-scale genomics unveil polygenic architecture of human cortical surface area

scientific article published on 20 July 2015

Linkage-disequilibrium-based binning affects the interpretation of GWASs

scientific article published on 22 March 2012

Lipid-lowering effects of tetradecylthioacetic acid in antipsychotic-exposed, female rats: challenges with long-term treatment ⬇️

scientific article published on November 30, 2012

Lipogenic effects of psychotropic drugs: focus on the SREBP system

scientific article published on January 2011

Lithium differentially affects clock gene expression in serum-shocked NIH-3T3 cells.

scientific article published on 13 September 2010

MicroRNAs enrichment in GWAS of complex human phenotypes

scientific article

Molecular genetic evidence for overlap between general cognitive ability and risk for schizophrenia: a report from the Cognitive Genomics consorTium (COGENT).

scientific article published on 17 December 2013

Multi-Trait Analysis of GWAS and Biological Insights Into Cognition: A Response to Hill (2018)

scientific article published on 13 July 2018

Mutations in ABHD12 cause the neurodegenerative disease PHARC: An inborn error of endocannabinoid metabolism

scientific article

Neomycin does not interfere with the inositol phospholipid metabolism, but blocks binding of alpha-thrombin to intact human platelets

scientific article published on January 1991

Neomycin inhibits platelet functions and inositol phospholipid metabolism upon stimulation with thrombin, but not with ionomycin or 12-O-tetradecanoyl-phorbol 13-acetate

scientific article published on 01 October 1988

Neurogenetic effects on cognition in aging brains: a window of opportunity for intervention?

scientific article

Neuropsychological deficits in mice depleted of the schizophrenia susceptibility gene CSMD1.

scientific article

Ninety-nine independent genetic loci influencing general cognitive function include genes associated with brain health and structure (N = 280,360)

Nomenclature for human CYP2D6 alleles

scientific article published in June 1996

Non-functional CYP2D6 alleles and risk for neuroleptic-induced movement disorders in schizophrenic patients

scientific article published on 01 May 1997

Novel genetic loci associated with hippocampal volume

scientific article published on 18 January 2017

Novel genetic loci underlying human intracranial volume identified through genome-wide association

scientific article (publication date: 3 October 2016)

Obesity, dyslipidemia, and diabetes with selective serotonin reuptake inhibitors: the Hordaland Health Study.

scientific article published in December 2006

Olanzapine depot exposure in male rats: Dose-dependent lipogenic effects without concomitant weight gain

scientific article published on 18 March 2015

Olanzapine depot formulation in rat: a step forward in modelling antipsychotic-induced metabolic adverse effects.

scientific article

Olanzapine, but not aripiprazole, weight-independently elevates serum triglycerides and activates lipogenic gene expression in female rats.

scientific article published on 19 August 2011

Olanzapine-induced hyperphagia and weight gain associate with orexigenic hypothalamic neuropeptide signaling without concomitant AMPK phosphorylation

scientific article

One-Year Treatment with Olanzapine Depot in Female Rats: Metabolic Effects

Pharmacogenetics of tardive dyskinesia: combined analysis of 780 patients supports association with dopamine D3 receptor gene Ser9Gly polymorphism

scientific article

Pleiotropic Meta-Analysis of Cognition, Education, and Schizophrenia Differentiates Roles of Early Neurodevelopmental and Adult Synaptic Pathways

scientific article published on 01 August 2019

Polymorphisms in CYP2D6 duplication-negative individuals with the ultrarapid metabolizer phenotype: a role for the CYP2D6*35 allele in ultrarapid metabolism?

scientific article published on 01 February 2001

Polymorphisms in SREBF1 and SREBF2, two antipsychotic-activated transcription factors controlling cellular lipogenesis, are associated with schizophrenia in German and Scandinavian samples

scientific article

Potentiation by adrenaline of thrombin-induced elevation of pHi is not essential for synergistic activation of human platelets

scientific article published on 01 July 1989

Psychotropic drugs up-regulate the expression of cholesterol transport proteins including ApoE in cultured human CNS- and liver cells

scientific article published on 29 August 2009

Publisher Correction: Common brain disorders are associated with heritable patterns of apparent aging of the brain

scientific article published on 01 February 2020

RareVariantVis: new tool for visualization of causative variants in rare monogenic disorders using whole genome sequencing data

scientific article

Recently evolved human-specific methylated regions are enriched in schizophrenia signals.

scientific article published on 11 May 2018

Role of the Neutral Amino Acid Transporter Slc7a10 in Adipocyte Lipid Storage, Obesity and Insulin Resistance

scientific article published on 06 January 2021

Runaway multi-allelic copy number variation at the α-defensin locus in African and Asian populations

scientific article published on 04 June 2020

S87. THE INITIAL CHANGE IN THE SERUM LEVEL OF C-REACTIVE PROTEIN IN ACUTE PSYCHOSIS IS ASSOCIATED WITH COGNITIVE PERFORMANCE IN LATER PHASES.

scientific article published in April 2018

SREBP activation by antipsychotic- and antidepressant-drugs in cultured human liver cells: relevance for metabolic side-effects?

scientific article published on 23 May 2006

SU117. Peripheral Cytokines After 3 Weeks of Antipsychotic Treatment.

scientific article

Ser9Gly dopamine D3 receptor polymorphism and spontaneous dyskinesia in never-medicated schizophrenic patients

scientific article published in January 2001

Serum concentrations of tamoxifen and its metabolites increase with age during steady-state treatment

scientific article published on September 2013

Stimulation of human platelets with low concentrations of thrombin: evidence for equimolar accumulation of inositol trisphosphates and phosphatidic acid

scientific article published on 01 January 1991

Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function ⬇️

scientific article published on 29 May 2018

Subchronic olanzapine exposure leads to increased expression of myelination-related genes in rat fronto-medial cortex.

scientific article published on 30 November 2017

Switch from stress response to homeobox transcription factors in adipose tissue after profound fat loss

scientific article

Synaptic activity-induced global gene expression patterns in the dentate gyrus of adult behaving rats: induction of immunity-linked genes

scientific article published on 21 July 2007

Syndromic X-linked intellectual disability segregating with a missense variant in RLIM.

scientific article published on 4 March 2015

Synergism between thrombin and adrenaline (epinephrine) in human platelets. Marked potentiation of inositol phospholipid metabolism

scientific article published on July 1988

Synergism between thrombin and epinephrine in human platelets: different dose-response relationships for aggregation and dense granule secretion.

scientific article

The CYP2C19 genotype and the use of oral contraceptives influence the pharmacokinetics of carisoprodol in healthy human subjects

scientific article published on 15 July 2005

The ENIGMA Consortium: large-scale collaborative analyses of neuroimaging and genetic data

scientific article

The complement control-related genes CSMD1 and CSMD2 associate to schizophrenia

scientific article published on 24 March 2011

The genetic architecture of human brainstem structures and their involvement in common brain disorders

scientific article published on 11 August 2020

The genetic architecture of the human cerebral cortex

The genetic architecture of the human cerebral cortex

scientific article

The phospholipase C-gamma1 gene (PLCG1) and lithium-responsive bipolar disorder: re-examination of an intronic dinucleotide repeat polymorphism

scientific article published on 01 March 2001

The platelet-stimulating effect of adrenaline through alpha 2-adrenergic receptors requires simultaneous activation by a true stimulatory platelet agonist. Evidence that adrenaline per se does not induce human platelet activation in vitro

scientific article published on 01 September 1993

The polymorphic inositol polyphosphate 1-phosphatase gene as a candidate for pharmacogenetic prediction of lithium-responsive manic-depressive illness

scientific article published on June 1, 1998

The serum level of C-reactive protein (CRP) is associated with cognitive performance in acute phase psychosis

scientific article

Transcriptional, post-transcriptional and chromatin-associated regulation of pri-miRNAs, pre-miRNAs and moRNAs

scientific article published on 15 December 2015

Ultrarapid metabolizers of debrisoquine: Characterization and PCR-based detection of alleles with duplication of the CYP2D6 gene

article

Upregulation of immunoglobulin-related genes in cortical sections from multiple sclerosis patients

scientific article published on 16 October 2009

Usefulness of factor V Leiden mutation testing in clinical practice

scientific article

Variants in doublecortin- and calmodulin kinase like 1, a gene up-regulated by BDNF, are associated with memory and general cognitive abilities

scientific article published on 21 October 2009

Williams Syndrome neuroanatomical score associates with GTF2IRD1 in large-scale magnetic resonance imaging cohorts: a proof of concept for multivariate endophenotypes.

scientific article published on 8 June 2018

[Pharmacogenetics and tailored drug treatment in schizophrenia]

scientific article published on 01 September 2006

[Schizophrenia and molecular genetics]

scientific article published on 01 September 2002

Paulina is supported by:

About Paulina

Help