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List of works by Jan Trka

Absence of SBDS mutations in sporadic paediatric acute myeloid leukaemia

scientific article published on 28 November 2012

Acute leukemias with ETV6/ABL1 (TEL/ABL) fusion: poor prognosis and prenatal origin.

scientific article published on October 2010

Acute lymphoblastic leukemia with aleukemic prodrome: preleukemic dynamics and possible mechanisms of immunosurveillance

scientific article published on 2 March 2017

Adaptor molecules expression in normal lymphopoiesis and in childhood leukemia

scientific article published on 11 February 2009

BCL11A deletions result in fetal hemoglobin persistence and neurodevelopmental alterations

scientific article

CANCERTOOL: A Visualization and Representation Interface to Exploit Cancer Datasets

scientific article published on 19 September 2018

Characterization of CEBPA mutations and promoter hypermethylation in pediatric acute myeloid leukemia

scientific article

Characterization of leukemias with ETV6-ABL1 fusion

scientific article published on 26 May 2016

Covert preleukemia driven by MLL gene fusion

scientific article published in January 2009

Cutting edge: TCR delta gene is frequently rearranged in adult B lymphocytes

scientific article

Detection of prognostically relevant genetic abnormalities in childhood B-cell precursor acute lymphoblastic leukaemia: recommendations from the Biology and Diagnosis Committee of the International Berlin-Frankfürt-Münster study group

scientific article published on October 2010

Detection of residual B precursor lymphoblastic leukemia by uniform gating flow cytometry

scientific article published in January 2010

ETV6/RUNX1-like acute lymphoblastic leukemia: A novel B-cell precursor leukemia subtype associated with the CD27/CD44 immunophenotype.

scientific article published on 10 April 2017

Evaluation of gene expression signatures predictive of cytogenetic and molecular subtypes of pediatric acute myeloid leukemia

scientific article

High GATA2 expression is a poor prognostic marker in pediatric acute myeloid leukemia ⬇️

scientific article published on July 11, 2012

Homeobox gene expression in acute myeloid leukemia is linked to typical underlying molecular aberrations

scientific article

IKZF1 status as a prognostic feature in BCR-ABL1-positive childhood ALL.

scientific article

Implications of delayed bone marrow aspirations at the end of treatment induction for risk stratification and outcome in children with acute lymphoblastic leukaemia

scientific article

Intensive chemotherapy for childhood acute lymphoblastic leukemia: results of the randomized intercontinental trial ALL IC-BFM 2002.

scientific article published on 16 December 2013

International cooperative study identifies treatment strategy in childhood ambiguous lineage leukemia.

scientific article published on 2 May 2018

Intragenic ERG Deletions Do Not Explain the Biology of ERG-Related Acute Lymphoblastic Leukemia.

scientific article

Intragenic amplification of : a novel subgroup in B-cell precursor acute lymphoblastic leukemia?

scientific article published on 14 August 2017

Is Next-Generation Sequencing the way to go for Residual Disease Monitoring in Acute Lymphoblastic Leukemia?

scientific article published on 27 April 2017

Loss of B cells and their precursors is the most constant feature of GATA-2 deficiency in childhood myelodysplastic syndrome.

scientific article published on 24 March 2016

Low expression of asparagine synthetase in lymphoid blasts precludes its role in sensitivity to L-asparaginase ⬇️

scientific article published on April 25, 2012

Lymphoid differentiation pathways can be traced by TCR delta rearrangements

scientific article

MicroRNA-106b~25 cluster is upregulated in relapsed MLL-rearranged pediatric acute myeloid leukemia

scientific article published on 24 June 2016

Minimal residual disease in peripheral blood at day 15 identifies a subgroup of childhood B-cell precursor acute lymphoblastic leukemia with superior prognosis ⬇️

scientific article published on August 31, 2011

Molecular biology of testicular germ cell tumors: unique features awaiting clinical application

scientific article published on 11 October 2013

Mutations in exon 2 of GATA1 are early events in megakaryocytic malignancies associated with trisomy 21

scientific article (publication date: August 2003)

Mutations of JAK2 in acute lymphoblastic leukaemias associated with Down's syndrome

scientific article published on 19 September 2008

Myeloid antigens in childhood lymphoblastic leukemia: clinical data point to regulation of CD66c distinct from other myeloid antigens

scientific article

NQO1 C609T polymorphism in distinct entities of pediatric hematologic neoplasms.

scientific article published in December 2004

PHF6 mutations in paediatric acute myeloid leukaemia

scientific article published on 21 December 2015

PMEDAP and its N6-substituted derivatives: genotoxic effect and apoptosis in in vitro conditions.

scientific article published on November 2003

Pre-natal, clonal origin of acute lymphoblastic leukaemia in triplets

scientific article published on December 2003

Prenatal origin of childhood AML occurs less frequently than in childhood ALL.

scientific article published on 21 April 2006

Prognosis of children with mixed phenotype acute leukemia treated on the basis of consistent immunophenotypic criteria

scientific article published on 9 February 2010

Recurrent abnormalities can be used for risk group stratification in pediatric AMKL: a retrospective intergroup study

scientific article

Recurrent deletions of IKZF1 in pediatric acute myeloid leukemia

scientific article published on 11 June 2015

Reprogramming of B cell acute lymphoblastic leukemia cells: Do we need to shoot a moving target?

scientific article published on 11 June 2015

Slower molecular response to treatment predicts poor outcome in patients with TEL/AML1 positive acute lymphoblastic leukemia: prospective real-time quantitative reverse transcriptase-polymerase chain reaction study.

scientific article

Standardized flow cytometry for highly sensitive MRD measurements in B-cell acute lymphoblastic leukemia

scientific article

Submicroscopic bone marrow involvement in isolated extramedullary relapses in childhood acute lymphoblastic leukemia: a more precise definition of "isolated" and its possible clinical implications, a collaborative study of the Resistant Disease Comm

scientific article

The TREC/KREC assay for the diagnosis and monitoring of patients with DiGeorge syndrome.

scientific article

The predictive strength of next-generation sequencing MRD detection for relapse compared with current methods in childhood ALL.

scientific article published on August 2015

Valproic acid triggers differentiation and apoptosis in AML1/ETO-positive leukemic cells specifically

scientific article published on 17 January 2012

WT1 protein expression in childhood acute leukemia.

scientific article published on May 2008

Ad usum proprium: 1348-1953-2018

book edition published in 2018

Vědecká konference: 10.-11.4.2019, 2. LF UK, Velká posluchárna

book edition published in 2019

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