List of works by Morten Asser Karsdal

A Novel High Sensitivity Type II Collagen Blood-Based Biomarker, PRO-C2, for Assessment of Cartilage Formation ⬇️

scientific article published on 06 November 2018

Aggrecanase- and matrix metalloproteinase-mediated aggrecan degradation is associated with different molecular characteristics of aggrecan and separated in time ex vivo

scientific article published on 01 May 2010

An Ex Vivo Tissue Culture Model of Cartilage Remodeling in Bovine Knee Explants

scientific article published on 03 November 2019

Application of biochemical markers in development of drugs for treatment of osteoarthritis

scientific article published on February 2010

Associations between biomarkers of bone and cartilage turnover, gender, pain categories and radiographic severity in knee osteoarthritis

scientific article published on 03 September 2019

Biochemical markers of joint tissue turnover

scientific article published on February 2010

Biochemical markers of ongoing joint damage in rheumatoid arthritis--current and future applications, limitations and opportunities

scientific article

Biological relevance of citrullinations: diagnostic, prognostic and therapeutic options

scientific article

Biomarker of extracellular matrix remodelling C1M and proinflammatory cytokine interleukin 6 are related to synovitis and pain in end-stage knee osteoarthritis patients

scientific article published on 01 July 2017

Blockade of GM-CSF pathway induced sustained suppression of myeloid and T cell activities in rheumatoid arthritis.

scientific article

Bone phenotypes in rheumatology - there is more to bone than just bone

scientific article published on 28 November 2020

Characterization of an Ex vivo Femoral Head Model Assessed by Markers of Bone and Cartilage Turnover

scientific article

Chondrocyte activity is increased in psoriatic arthritis and axial spondyloarthritis.

scientific article published on 16 June 2016

Clinical Drug Development Using Dynamic Biomarkers to Enable Personalized Health Care in COPD.

scientific article published on July 2015

Clinical and biochemical factors associated with risk of total joint replacement and radiographic progression in osteoarthritis: Data from two phase III clinical trials

scientific article published on 15 March 2020

Collagen biology and non-invasive biomarkers of liver fibrosis

scientific article published on 19 February 2020

Connective tissue remodelling is differently modulated by tocilizumab versus methotrexate monotherapy in patients with early rheumatoid arthritis: the AMBITION study

scientific article published on 07 January 2021

Cross-Linked Multimeric Pro-Peptides of Type III Collagen (PC3X) in Hepatocellular Carcinoma - A Biomarker That Provides Additional Prognostic Value in AFP Positive Patients

scientific article published on 09 November 2020

Dermal fibroblasts have different extracellular matrix profiles induced by TGF-β, PDGF and IL-6 in a model for skin fibrosis

scientific article published on 14 October 2020

Diagnosis of Osteoarthritis by Cartilage Surface Smoothness Quantified Automatically from Knee MRI.

scientific article

Enzyme-linked immunosorbent assay (ELISAs) for metalloproteinase derived type II collagen neoepitope, CIIM--increased serum CIIM in subjects with severe radiographic osteoarthritis

scientific article published on 09 January 2011

Excessive matrix metalloprotease-mediated degradation of interstitial tissue (type I collagen) independently predicts short-term survival in an observational study of postmenopausal women diagnosed with cancer

scientific article published on 11 February 2017

Extracellular matrix remodeling: the common denominator in connective tissue diseases. Possibilities for evaluation and current understanding of the matrix as more than a passive architecture, but a key player in tissue failure

scientific article published on 9 October 2012

Extracellular matrix specific protein fingerprints measured in serum can separate pancreatic cancer patients from healthy controls

scientific article

Fragments of Citrullinated and MMP-degraded Vimentin and MMP-degraded Type III Collagen Are Novel Serological Biomarkers to Differentiate Crohn's Disease from Ulcerative Colitis

scientific article published on 17 July 2015

Future detection and monitoring of diabetes may entail analysis of both β-cell function and volume: how markers of β-cell loss may assist.

scientific article

GPDPLQ-A Type II Collagen Neo-Epitope Biomarker of Osteoclast- and Inflammation-Derived Cartilage Degradation in vitro

scientific article published on 28 February 2019

Glucocorticoids exert context-dependent effects on cells of the joint in vitro.

scientific article

IL-6 receptor inhibition modulates type III collagen and C-reactive protein degradation in rheumatoid arthritis patients with an inadequate response to anti-tumour necrosis factor therapy: analysis of connective tissue turnover in the tocilizumab RA

scientific article published on 31 January 2018

Identification of pain categories associated with change in pain in patients receiving placebo: data from two phase 3 randomized clinical trials in symptomatic knee osteoarthritis

scientific article published on 17 January 2018

Increased proteolytic cleavage of osteoglycin is associated with a stable plaque phenotype and lower risk of cardiovascular events

scientific article published in 2022

Increased remodelling of interstitial collagens and basement membrane is suppressed by treatment in patients with rheumatoid arthritis: serological evaluation of a one-year prospective study of 149 Japanese patients.

scientific article published on 14 February 2018

Intercritical circulating levels of neo-epitopes reflecting matrixmetalloprotease-driven degradation as markers of gout and frequent gout attacks

scientific article published on 2 June 2016

Investigation of chondrocyte hypertrophy and cartilage calcification in a full-depth articular cartilage explants model

scientific article published on 28 March 2012

Investigation of the direct effects of salmon calcitonin on human osteoarthritic chondrocytes

scientific article

Is cardiovascular disease in patients with diabetes associated with serum levels of MMP-2, LOX, and the elastin degradation products ELM and ELM-2?

scientific article

Matrix metalloproteinase-degraded type I collagen is associated with APOE/TOMM40 variants and preclinical dementia

scientific article published on 10 September 2020

Measurement of matrix metalloproteinase 9-mediated collagen type III degradation fragment as a marker of skin fibrosis

scientific article

Molecular serum and urine marker repertoire supporting clinical research on joint diseases

scientific article published on December 2011

Nidogen-1 Degraded by Cathepsin S can be Quantified in Serum and is Associated with Non-Small Cell Lung Cancer

scientific article published on 07 March 2017

Novel combinations of Post-Translational Modification (PTM) neo-epitopes provide tissue-specific biochemical markers--are they the cause or the consequence of the disease?

scientific article published on 08 April 2010

Novel insights into the function and dynamics of extracellular matrix in liver fibrosis

scientific article published on 12 March 2015

Oral salmon calcitonin--pharmacology in osteoporosis

scientific article published on 11 October 2010

Osteoclast Activity and Subtypes as a Function of Physiology and Pathology—Implications for Future Treatments of Osteoporosis ⬇️

scientific article published on September 17, 2010

PRO-C3, a Serological Marker of Fibrosis, During Childhood and Correlations With Fibrosis in Pediatric NAFLD

scientific article published on 08 July 2021

Procollagen type I N-terminal propeptide (PINP) is a marker for fibrogenesis in bile duct ligation-induced fibrosis in rats

scientific article

Protein biomarkers associated with pain mechanisms in osteoarthritis.

scientific article published on 25 April 2018

Recent advances in understanding the phenotypes of osteoarthritis

scientific article published on 12 December 2019

Remodeling of the Tumor Microenvironment Predicts Increased Risk of Cancer in Postmenopausal Women: The Prospective Epidemiologic Risk Factor (PERF I) Study.

scientific article published on 13 July 2016

Review article: the signalling and functional role of the extracellular matrix in the development of liver fibrosis

scientific article published on 17 May 2020

Rheumatoid arthritis: a case for personalized health care?

scientific article published on September 2014

Serological Assessment of the Quality of Wound Healing Processes in Crohn's Disease

scientific article published on 01 June 2019

Serological Biomarkers of Tissue Turnover Identify Responders to Anti-TNF Therapy in Crohn's Disease: A Pilot Study

scientific article published on 01 September 2020

Serum biomarkers of collagen turnover as potential diagnostic tools in diffuse systemic sclerosis: A cross-sectional study

scientific article published in PLoS ONE

Serum biomarkers reflecting specific tumor tissue remodeling processes are valuable diagnostic tools for lung cancer

scientific article

Serum cartilage oligomeric matrix protein and development of radiographic and painful knee osteoarthritis. A community-based cohort of middle-aged women.

scientific article published on 5 February 2016

Serum markers of liver fibrosis: combining the BIPED classification and the neo-epitope approach in the development of new biomarkers

scientific article published on January 2010

Serum tau fragments as predictors of death or poor neurological outcome after out-of-hospital cardiac arrest

scientific article published on 31 May 2019

Suppression of active, but not total MMP-3, is associated with treatment response in a phase III clinical study of rheumatoid arthritis

scientific article

Synovitis biomarkers: ex vivo characterization of three biomarkers for identification of inflammatory osteoarthritis

scientific article

The Citrullinated and MMP-degraded Vimentin Biomarker (VICM) Predicts Early Response to Anti-TNFα Treatment in Crohn's Disease

scientific article published on 14 April 2020

The active form of MMP-3 is a marker of synovial inflammation and cartilage turnover in inflammatory joint diseases.

scientific article

The disease modifying osteoarthritis drug (DMOAD): Is it in the horizon?

scientific article published on 08 June 2008

The dual amylin and calcitonin receptor agonist KBP-089 and the GLP-1 receptor agonist liraglutide act complimentarily on body weight reduction and metabolic profile

scientific article published on 07 January 2021

The inhibitory effect of salmon calcitonin on tri-iodothyronine induction of early hypertrophy in articular cartilage

scientific article

Tofacitinib and TPCA-1 exert chondroprotective effects on extracellular matrix turnover in bovine articular cartilage ex vivo

scientific article published on 29 July 2018

Treatment with a dual amylin and calcitonin receptor agonist improves metabolic health in an old, obese, and ovariectomized rat model

scientific article published on 04 January 2021

Type I and III collagen turnover is increased in axial spondyloarthritis and psoriatic arthritis. Associations with disease activity and diagnostic capacity

scientific article

Ulcerative colitis, Crohn's disease, and irritable bowel syndrome have different profiles of extracellular matrix turnover, which also reflects disease activity in Crohn's disease

scientific article published on 13 October 2017

Unique insight into microenvironmental changes in colorectal cancer: Ex vivo assessment of matrix metalloprotease-mediated molecular changes in human colorectal tumor tissue and corresponding non-neoplastic adjacent tissue

scientific article published on 23 March 2017

Which elements are involved in reversible and irreversible cartilage degradation in osteoarthritis?

scientific article published on 09 October 2009

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