List of works by Roger Bouillon

1 Alpha,25-dihydroxyvitamin D3 and its TX527 analog inhibit the growth of endothelial cells transformed by Kaposi sarcoma-associated herpes virus G protein-coupled receptor in vitro and in vivo.

scientific article

1,25-Dihydroxyvitamin D3 and analogues protect primary human keratinocytes against UVB-induced DNA damage

scientific article published in February 2005

1,25-Dihydroxyvitamin D3 and the aging-related forkhead box O and sestrin proteins in osteoblasts

scientific article published on 16 September 2012

1,25-Dihydroxyvitamin D3 inhibits ultraviolet B-induced apoptosis, Jun kinase activation, and interleukin-6 production in primary human keratinocytes

scientific article

1,25-Dihydroxyvitamin D3 modulates expression of chemokines and cytokines in pancreatic islets: implications for prevention of diabetes in nonobese diabetic mice

scientific journal article

1,25-dihydroxyvitamin D3 and a superagonistic analog in combination with paclitaxel or suberoylanilide hydroxamic acid have potent antiproliferative effects on anaplastic thyroid cancer

scientific article published on 21 December 2010

1,25-dihydroxyvitamin D3 influences cellular homocysteine levels in murine preosteoblastic MC3T3-E1 cells by direct regulation of cystathionine β-synthase.

scientific article published on December 2011

13th Workshop consensus for vitamin D nutritional guidelines

scientific article published on 17 January 2007

14th Vitamin D Workshop consensus on vitamin D nutritional guidelines

article

1alpha,25-Dihydroxyvitamin D3-induced down-regulation of the checkpoint proteins, Chk1 and Claspin, is mediated by the pocket proteins p107 and p130.

scientific article published on 22 December 2006

1β,25-Dihydroxyvitamin D3: A new vitamin D metabolite in human serum

scientific article published on 10 February 2017

A brown tumor after biliopancreatic diversion for severe obesity

scientific article published on 27 December 2008

A homozygous inactivating calcium-sensing receptor mutation, Pro339Thr, is associated with isolated primary hyperparathyroidism: correlation between location of mutations and severity of hypercalcaemia

scientific article

A new missense mutation in the CASR gene in familial interstitial lung disease with hypocalciuric hypercalcemia and defective granulocyte function

scientific article published on 01 March 2008

A novel nonsense mutation in the ligand binding domain of the vitamin D receptor causes hereditary 1,25-dihydroxyvitamin D-resistant rickets

scientific article published in December 2002

A structural basis for the unique binding features of the human vitamin D-binding protein

scientific article

A thyroid thriller: acute transient and symmetric goiter after fine-needle aspiration of a solitary thyroid nodule

scientific article published on 01 January 2008

Actin-DBP: the perfect structural fit?

scientific article (publication date: February 2003)

Active intestinal calcium transport in the absence of transient receptor potential vanilloid type 6 and calbindin-D9k

scientific article published on 6 March 2008

Acute shock induced by antigen vaccination in NOD mice

scientific article published in February 2003

Altered Vitamin D receptor-coactivator interactions reflect superagonism of Vitamin D analogs

scientific article

Analogs of 1alpha,25-dihydroxyvitamin D3 as pluripotent immunomodulators

scientific article

Androgens and Bone

Antiproliferative and calcemic actions of trans-decalin CD-ring analogs of 1,25-dihydroxyvitamin D3.

scientific article

Association between 25-hydroxyvitamin D levels and cognitive performance in middle-aged and older European men.

scientific article published on 21 May 2009

Association of hypogonadism with vitamin D status: the European Male Ageing Study

scientific article published on 02 November 2011

Associations of 25-Hydroxyvitamin D and 1,25-Dihydroxyvitamin D With Bone Mineral Density, Bone Mineral Density Change, and Incident Nonvertebral Fracture.

scientific article published on 22 May 2015

Biological activity and conformational analysis of C20 and C14 epimers of CD-ring modified trans-decalin 1alpha,25-dihydroxyvitamin D analogs

scientific article

Bone and metabolism: a complex crosstalk

scientific article published on 21 January 2009

Bone and muscle protective potential of the prostate-sparing synthetic androgen 7alpha-methyl-19-nortestosterone: evidence from the aged orchidectomized male rat model

scientific article published in April 2005

Bone: Which model to predict fracture risk?

scientific article published on 11 February 2014

CD-ring modified vitamin D3 analogs and their superagonistic action.

scientific article published on 02 February 2010

Calcifediol or vitamin D to optimize vitamin D status: Reply to letter of M Sosas

scientific article published on 14 October 2019

Characterization of the condensin component Cnap1 and protein kinase Melk as novel E2F target genes down-regulated by 1,25-dihydroxyvitamin D3.

scientific article

Chemoenzymatic synthesis and biological evaluation of C-3 carbamate analogues of 1alpha,25-dihydroxyvitamin D3.

scientific article published on October 2004

Clinical Applications for Vitamin D Assays: What Is Known and What Is Wished for

scientific article published on 18 April 2011

Clinical Review: Sex steroids and the periosteum--reconsidering the roles of androgens and estrogens in periosteal expansion

scientific article

Clinical relevance of thyroid fluorodeoxyglucose-whole body positron emission tomography incidentaloma

scientific article

Controversies in Vitamin D: A Statement From the Third International Conference

scientific article published on 10 November 2020

Controversies in Vitamin D: Summary Statement from an International Conference

scientific article published on 01 February 2019

Current vitamin D status in European and Middle East countries and strategies to prevent vitamin D deficiency: a position statement of the European Calcified Tissue Society

scientific article published on 01 April 2019

Defect in activation-induced cell death in non-obese diabetic (NOD) T lymphocytes.

scientific article

Deletion of the vitamin D receptor specifically in the parathyroid demonstrates a limited role for the receptor in parathyroid physiology

scientific article published on 19 August 2009

Dermal fibroblasts pretreated with a sterol Delta7-reductase inhibitor produce 25-hydroxyvitamin D3 upon UVB irradiation

scientific article published on 07 July 2006

Determination of Free 25(OH)D Concentrations and Their Relationships to Total 25(OH)D in Multiple Clinical Populations

Development of a method for the quantification of 1alpha,25(OH)2-vitamin D3 in serum by liquid chromatography tandem mass spectrometry without derivatization

scientific article published in January 2010

Differential effects on bone of estrogen receptor alpha and androgen receptor activation in orchidectomized adult male mice

scientific article

Differential regulation of bone and body composition in male mice with combined inactivation of androgen and estrogen receptor-alpha.

scientific article published on 22 September 2008

Disorders of calcium homeostasis

scientific article published on December 2003

Does a better vitamin D status help to reduce cardiovascular risks and events?

scientific article published on 26 September 2014

Duodenal calcium absorption in dexamethasone-treated mice: functional and molecular aspects

scientific article published on 12 December 2006

Effect of Intravenous 25OHD Supplementation on Bone Turnover and Inflammation in Prolonged Critically Ill Patients

scientific article published on 25 March 2020

Endocrine determinants of incident sarcopenia in middle-aged and elderly European men.

scientific article

Estrogens and Androgens in Skeletal Physiology and Pathophysiology

scientific article

Estrogens are essential for male pubertal periosteal bone expansion

scientific article published in December 2004

Fifteenth vitamin D workshop

scientific article

Fourteenth Workshop on Vitamin D.

scientific article published on 4 June 2010

Free 25-Hydroxyvitamin D: Impact of Vitamin D Binding Protein Assays on Racial-Genotypic Associations

scientific article published on 23 March 2016

Growth hormone and bone health

scientific article published on January 2003

Growth without growth hormone receptor: estradiol is a major growth hormone-independent regulator of hepatic IGF-I synthesis

scientific article

High doses of vitamin D to reduce exacerbations in chronic obstructive pulmonary disease: a randomized trial

scientific article published in January 2012

Higher 25(OH)D2 is associated with lower 25(OH)D3 and 1,25(OH)2D3

scientific article

Highlights from the 18th workshop on vitamin D, Delft, The Netherlands, April 21-24, 2015.

scientific article published in November 2016

Highlights from the 19th Workshop on Vitamin D in Boston, March 29-31, 2016.

scientific article published in October 2017

Highlights from the 20th Workshop on Vitamin D in Orlando, Mar. 28-31, 2017.

scientific article published on 24 November 2017

How Important Is Vitamin D for Calcium Homeostasis During Pregnancy and Lactation?

scientific article published on 22 November 2017

Human growth hormone replacement in adult hypopituitary patients: long-term effects on body composition and lipid status--3-year results from the HypoCCS Database

scientific article

Hypervitaminosis D Associated With Tanning Bed Use: A Case Report

scientific article

Hypogonadism in male outpatients with sarcoidosis

scientific article published on 12 September 2007

Hypogonadism, quadriceps weakness, and exercise intolerance in chronic obstructive pulmonary disease

scientific article published on 11 August 2005

Identification of 70 calcium-sensing receptor mutations in hyper- and hypo-calcaemic patients: evidence for clustering of extracellular domain mutations at calcium-binding sites.

scientific article published on 14 March 2012

Immune regulation of 25-hydroxyvitamin D-1alpha-hydroxylase in human monocytic THP1 cells: mechanisms of interferon-gamma-mediated induction

scientific article published on 20 June 2006

Immune regulation of 25-hydroxyvitamin-D3-1alpha-hydroxylase in human monocytes

scientific article published on 19 September 2005

Impact of androgens, growth hormone, and IGF-I on bone and muscle in male mice during puberty.

scientific article published in January 2007

Is Vitamin D2 Really Bioequivalent to Vitamin D3?

scientific article published on 01 September 2016

Is calcifediol better than cholecalciferol for vitamin D supplementation?

scientific article published on 30 April 2018

List of Contributors

Low vitamin D and the risk of developing chronic widespread pain: results from the European male ageing study

scientific article published on 16 January 2016

Lower vitamin D levels are associated with depression among community-dwelling European men.

scientific article published on 7 September 2010

Management of Hypoparathyroidism: Summary Statement and Guidelines

scientific article published on 4 March 2016

Mechanisms for the selective action of Vitamin D analogs

scientific article

Microarray analysis of 1alpha,25-dihydroxyvitamin D3-treated MC3T3-E1 cells

scientific article published on May 2004

Microarray analysis of MCF-7 breast cancer cells treated with 1,25-dihydroxyvitamin D3 or a 17-methyl-D-ring analog.

scientific article

Molecular pathways involved in the anti-apoptotic effect of 1,25-dihydroxyvitamin D3 in primary human keratinocytes

scientific article published in November 2004

Monocytes from type 2 diabetic patients have a pro-inflammatory profile. 1,25-Dihydroxyvitamin D(3) works as anti-inflammatory

scientific article published on 16 November 2006

Musculoskeletal effects of the recombinant human IGF-I/IGF binding protein-3 complex in osteoporotic patients with proximal femoral fracture: a double-blind, placebo-controlled pilot study

scientific article published on April 2002

Musculoskeletal pain is associated with very low levels of vitamin D in men: results from the European Male Ageing Study

scientific article published on 24 May 2010

NIH deltanoids meeting on Vitamin D and cancer. Conclusion and strategic options

scientific article published on 25 July 2005

NOD bone marrow-derived dendritic cells are modulated by analogs of 1,25-dihydroxyvitamin D3.

scientific article

Need for additional calcium to reduce the risk of hip fracture with vitamin d supplementation: evidence from a comparative metaanalysis of randomized controlled trials

scientific article published on 30 January 2007

Normocalcemia is maintained in mice under conditions of calcium malabsorption by vitamin D-induced inhibition of bone mineralization.

scientific article published on 23 April 2012

Novel A-ring homodimeric C-3-carbamate analogues of 1alpha,25-dihydroxyvitamin D3: synthesis and preliminary biological evaluation

scientific article published on August 2006

Novel insights in the immune function of the vitamin D system: synergism with interferon-beta

scientific article published on 23 December 2006

NuSAP, a novel microtubule-associated protein involved in mitotic spindle organization

scientific article

Optimal vitamin D status: a critical analysis on the basis of evidence-based medicine

scientific article

Optimizing the benefits of bisphosphonates in osteoporosis : the importance of appropriate calcium intake

scientific article published on 01 January 2006

Perturbed insulin-like growth factor-1 (IGF-1) and IGF binding protein-3 are not associated with chronic widespread pain in men: results from the European Male Ageing Study

scientific article published on 15 October 2009

Physical activity in the androgen receptor knockout mouse: evidence for reversal of androgen deficiency on cancellous bone.

scientific article published on 12 November 2008

Physiological functions of vitamin D: what we have learned from global and conditional VDR knockout mouse studies

scientific article published on May 2015

Pregnancy in mice lacking the vitamin D receptor: normal maternal skeletal response, but fetal hypomineralization rescued by maternal calcium supplementation

scientific article

Presentation of Hypoparathyroidism: Etiologies and Clinical Features

scientific article

Prevalence and incidence of diabetes mellitus in adult patients on growth hormone replacement for growth hormone deficiency: a surveillance database analysis

scientific article

Prevention and consequences of vitamin D deficiency in pregnant and lactating women and children: A symposium to prioritise vitamin D on the global agenda

scientific article published on 10 November 2015

Previtamin D3 with a trans-fused decalin CD-ring has pronounced genomic activity.

scientific article

Prospects for vitamin D receptor modulators as candidate drugs for cancer and (auto)immune diseases.

scientific article

REGULATION OF CYSTATHIONINE BETA SYNTHASE BY 1α,25-DIHYDROXYVITAMIN D3

Rationale and Plan for Vitamin D Food Fortification: A Review and Guidance Paper

article

Redirection of human autoreactive T-cells Upon interaction with dendritic cells modulated by TX527, an analog of 1,25 dihydroxyvitamin D(3).

scientific article published in July 2002

Reducing fracture risk with calcium and vitamin D.

scientific article published on September 2010

Regulation of 25-hydroxyvitamin d-1alpha-hydroxylase by IFNgamma in human monocytic THP1 cells

scientific article published on May 2004

Regulation of semaphorin 3 family members and their receptors by 1α,25-dihydroxyvitamin D3

Relationship of Total and Free 25-Hydroxyvitamin D to Biomarkers and Metabolic Indices in Healthy Children

scientific article published on 01 April 2020

Relative impact of androgen and estrogen receptor activation in the effects of androgens on trabecular and cortical bone in growing male mice: a study in the androgen receptor knockout mouse model

scientific article published on 05 April 2006

Removal of C-ring from the CD-ring skeleton of 1alpha,25-dihydroxyvitamin D3 does not alter its target tissue metabolism significantly

scientific article published on 21 November 2006

Rickets in transgenic animals

scientific article

Role of Assay Type in Determining Free 25-Hydroxyvitamin D Levels in Diverse Populations

scientific article published on 23 March 2016

Role of the androgen receptor in skeletal homeostasis: the androgen-resistant testicular feminized male mouse model

scientific article

Seasonality of birth in patients with type 1 diabetes

scientific article

Skeletal and extra-skeletal actions of vitamin D: Current evidence and outstanding questions

scholarly article by Roger Bouillon et al published 12 October 2018 in Endocrine Reviews

Sunscreen photoprotection and vitamin D status

scientific article published on 15 July 2019

Superagonistic action of 14-epi-analogs of 1,25-dihydroxyvitamin D explained by vitamin D receptor-coactivator interaction

scientific article

Superagonistic fluorinated vitamin D3 analogs stabilize helix 12 of the vitamin D receptor

scientific article

Synthesis and biological activity of 22-oxa CD-ring modified analogues of 1alpha,25-dihydroxyvitamin D3: cis-perhydrindane CE-ring analogues

scientific article published on August 2004

Synthesis and biological activity of 22-oxa CD-ring modified analogues of 1alpha,25-dihydroxyvitamin D3: spiro[5.5]undecane CF-ring analogues

scientific article

Synthesis of spiro[4.5]decane CF-ring analogues of 1 alpha,25-dihydroxyvitamin D3

scientific article published on 01 September 2006

Synthesis, biological activity, and conformational analysis of CD-ring modified trans-decalin 1 alpha,25-dihydroxyvitamin D analogs.

scientific article published in January 2003

Synthesis, structure, and biological activity of des-side chain analogues of 1α,25-dihydroxyvitamin D3 with substituents at C18

scientific article

TRPV4-mediated calcium influx regulates terminal differentiation of osteoclasts

scientific article published in September 2008

Textiloma-Induced 1,25-Dihydroxyvitamin D-Mediated Hypercalcemia: A Case Report and Literature Study

scientific article published on 27 August 2019

The E2F-regulated gene Chk1 is highly expressed in triple-negative estrogen receptor /progesterone receptor /HER-2 breast carcinomas

scientific article

The development of CD-ring modified analogs of 1alpha,25-dihydroxyvitamin D.

scientific article

The diagnosis and treatment of male osteoporosis: Defining, assessing, and preventing skeletal fragility in men

scientific article published on 01 January 2007

The effects of 1alpha,25-dihydroxyvitamin D3 on the expression of DNA replication genes

scientific article published on January 2004

The effects of growth hormone replacement therapy on bone metabolism in adult-onset growth hormone deficiency: a 2-year open randomized controlled multicenter trial

scientific article

The impact of 1,25(OH)2D3 and its structural analogs on gene expression in cancer cells--a microarray approach.

scientific article published on September 2009

The sunshine hormone vitamin D and its association with type 1 diabetes

scientific article published on 01 August 2005

The vitamin D receptor gene FokI polymorphism: functional impact on the immune system.

scientific article published in February 2007

The vitamin d receptor in thyroid development and function

scientific article published on 22 September 2012

The white adipose tissue connection with calcium and bone homeostasis

scientific article published on 01 August 2010

Total, Bioavailable, and Free 25(OH)D Relationship with Indices of Bone Health in Elderly: A Randomized Controlled Trial

scientific article published on 06 December 2020

Two 14-epi analogues of 1,25-dihydroxyvitamin D3 protect human keratinocytes against the effects of UVB.

scientific article published on 20 March 2004

UVB-induced 1,25(OH)2D3 production and vitamin D activity in intestinal CaCo-2 cells and in THP-1 macrophages pretreated with a sterol Delta7-reductase inhibitor

scientific article published on September 2006

UVB-induced production of 1,25-dihydroxyvitamin D3 and vitamin D activity in human keratinocytes pretreated with a sterol delta7-reductase inhibitor

scientific article published on May 2006

Unaltered diabetes presentation in NOD mice lacking the vitamin D receptor

scientific article published on 24 October 2007

Versatile synthesis and biological evaluation of 1,3-diamino-substituted 1alpha,25-dihydroxyvitamin D3 analogues.

scientific article published on 4 October 2005

Vitamin D Binding Protein: A Historic Overview

scientific article published on 01 January 2019

Vitamin D Metabolism Revised: Fall of Dogmas

scientific article published on 29 October 2019

Vitamin D action: lessons from VDR and Cyp27b1 null mice

scientific article published on June 2013

Vitamin D analogs and coactivators.

scientific article published on July 2006

Vitamin D and 1,25-dihydroxyvitamin D3 as modulators in the immune system

scientific article published in May 2004

Vitamin D and SARS-CoV-2 virus/COVID-19 disease

scientific article published on 13 May 2020

Vitamin D and cancer

scientific article published on 01 December 2006

Vitamin D and cardiovascular disorders

scientific article published on 11 August 2019

Vitamin D and energy homeostasis: of mice and men.

scientific article

Vitamin D and health: perspectives from mice and man.

scientific article published on July 2008

Vitamin D and human health: lessons from vitamin D receptor null mice.

scientific article published on 11 August 2008

Vitamin D assays and the definition of hypovitaminosis D: results from the First International Conference on Controversies in Vitamin D

scholarly article by Christopher T Sempos et al published October 2018 in British Journal of Clinical Pharmacology

Vitamin D beyond bones in chronic obstructive pulmonary disease: time to act.

scientific article published on 22 January 2009

Vitamin D deficiency

scientific article published on 01 November 2007

Vitamin D deficiency is highly prevalent in COPD and correlates with variants in the vitamin D-binding gene

scientific article published on 08 December 2009

Vitamin D in thyroid tumorigenesis and development

scientific article published on 26 July 2013

Vitamin D insufficiency: Definition, diagnosis and management

scientific article published on 03 October 2018

Vitamin D metabolites in captivity? Should we measure free or total 25(OH)D to assess vitamin D status?

scientific article

Vitamin D nutritional policy needs a vision for the future ⬇️

scientific article published on July 28, 2010

Vitamin D receptor and vitamin D action in muscle

scientific article published on 01 September 2014

Vitamin D resistance

Vitamin D signaling in calcium and bone homeostasis: a delicate balance

scientific article published on 30 June 2015

Vitamin D status at breast cancer diagnosis: correlation with tumor characteristics, disease outcome, and genetic determinants of vitamin D insufficiency

scientific article published on 23 May 2012

Vitamin D supplementation and musculoskeletal health

scientific article published on 01 February 2019

Vitamin D supplementation in respiratory diseases: evidence from randomized controlled trials.

scientific article

Vitamin D(3): synthesis of seco C-9,11,21-trisnor-17-methyl-1 alpha, 25-dihydroxyvitamin D(3) analogues

scientific article

Vitamin D(3): synthesis of seco-C-9,11-bisnor-17-methyl-1 alpha,25-dihydroxyvitamin D(3) analogues

scientific article published in June 2002

Vitamin D, mitochondria, and muscle

scientific article published in March 2013

Vitamin D, parathyroid hormone and the metabolic syndrome in middle-aged and older European men.

scientific article published on 22 September 2009

Vitamin D-binding protein and vitamin D in blacks and whites

Vitamin D: Giveth to Those Who Needeth

scientific article published on 14 November 2019

Vitamin D: a pleiotropic hormone

scientific article

Vitamin D: calcium and bone homeostasis during evolution

scientific article published on 08 January 2014

Vitamin D: direct effects of vitamin D metabolites on bone: lessons from genetically modified mice

scientific article

WY 1048, a 17-methyl 19-nor D-ring analog of vitamin D3, in combination with risedronate restores bone mass in a mouse model of postmenopausal osteoporosis

scientific article published on 03 January 2019

Paulina is supported by:

About Paulina

Help