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List of works by Piero Ruscitti

A comprehensive review on adult onset Still's disease

scientific article published on 01 August 2018

Adipocytokines in Rheumatoid Arthritis: The Hidden Link between Inflammation and Cardiometabolic Comorbidities

scientific article published on 21 November 2018

Adipose stromal vascular fraction and regenerative therapy in SSc: response to the article by Magalon et al

scientific article published on 02 February 2019

Adult-onset Still's disease: an Italian multicentre retrospective observational study of manifestations and treatments in 245 patients

scientific article

Adult-onset Still's disease: evaluation of prognostic tools and validation of the systemic score by analysis of 100 cases from three centers

scientific article

Advances in immunopathogenesis of macrophage activation syndrome during rheumatic inflammatory diseases: toward new therapeutic targets?

scientific article published on 24 August 2017

Anakinra Drug Retention Rate and Predictive Factors of Long-Term Response in Systemic Juvenile Idiopathic Arthritis and Adult Onset Still Disease

scientific article published on 23 August 2019

Angiogenic cytokines and growth factors in systemic sclerosis.

scientific article

Anti-TNF treatment response in rheumatoid arthritis patients with moderate disease activity: a prospective observational multicentre study (MODERATE).

scientific article

Anti-interleukin-1 treatment in patients with rheumatoid arthritis and type 2 diabetes (TRACK): A multicentre, open-label, randomised controlled trial

scientific article published on 12 September 2019

Biologic drugs in adult onset Still's disease: a systematic review and meta-analysis of observational studies

scientific article published on 5 September 2017

Biologic therapies and infections in the daily practice of three Italian rheumatologic units: a prospective, observational study.

scientific article

Blocking CD248 molecules in perivascular stromal cells of patients with systemic sclerosis strongly inhibits their differentiation toward myofibroblasts and proliferation: a new potential target for antifibrotic therapy

scientific article published on 03 October 2018

Cardiometabolic Comorbidities in Autoimmune Rheumatic Diseases: From Pathogenesis to Treatment

scientific article published on 01 January 2018

Cardiovascular Disease in Primary Sjögren's Syndrome

scientific article published on 01 January 2018

Cardiovascular Risk Prediction in Ankylosing Spondylitis: From Traditional Scores to Machine Learning Assessment

scientific article published on 16 September 2020

Cardiovascular and Metabolic Comorbidities in Rheumatoid Arthritis

scientific article published on 05 November 2018

Changing the outcome measures, changing the results? The urgent need of a specific disease activity score to adult-onset Still's disease

scientific article published on 03 July 2020

Clinical Features at Onset and Genetic Characterization of Pediatric and Adult Patients with TNF-α Receptor-Associated Periodic Syndrome (TRAPS): A Series of 80 Cases from the AIDA Network

scientific article published on 07 August 2020

Comparison of Early vs. Delayed Anakinra Treatment in Patients With Adult Onset Still's Disease and Effect on Clinical and Laboratory Outcomes

scientific article published on 21 February 2020

Computed Tomography and MR Imaging in Rheumatoid Arthritis.

scientific article published on 12 June 2017

Could Sars-coronavirus-2 trigger autoimmune and/or autoinflammatory mechanisms in genetically predisposed subjects?

scientific article published on 24 March 2020

Cytokine storm syndrome in severe COVID-19

scientific article published on 03 May 2020

Diagnostic and interventional radiology fundamentals of synovial pathology

scientific article published on 13 July 2020

Different operators and histologic techniques in the assessment of germinal center-like structures in primary Sjögren's syndrome minor salivary glands

scientific article published in PLoS ONE

Dose adjustments and discontinuation in TNF inhibitors treated patients: when and how. A systematic review of literature

scientific article published on 01 October 2018

Downregulation of miRNA17-92 cluster marks Vγ9Vδ2 T cells from patients with rheumatoid arthritis

article

Early assessment of sub-clinical cardiac involvement in systemic sclerosis (SSc) using delayed enhancement cardiac magnetic resonance (CE-MRI).

scientific article

Efficacy and safety of imatinib mesylate in systemic sclerosis. A systematic review and meta-analysis

scientific article published on 07 September 2020

Efficacy and safety of rituximab treatment in early primary Sjögren's syndrome: a prospective, multi-center, follow-up study

scientific article published on 30 October 2013

Efficacy of inhibition of IL-1 in patients with rheumatoid arthritis and type 2 diabetes mellitus: two case reports and review of the literature

scientific article published on 2 June 2015

Epidermal Growth Factor Like-domain 7 and miR-126 are abnormally expressed in diffuse Systemic Sclerosis fibroblasts

scientific article published on 14 March 2019

Erratum to “Is minor salivary gland biopsy more than a diagnostic tool in primary Sjo¨gren’s syndrome? Association between clinical, histopathological, and molecular features: A retrospective study” [Semin Arthritis Rheum 44 (2014) 314–324]

scholarly article published in Seminars in Arthritis and Rheumatism

Ferritin and C-reactive protein are predictive biomarkers of mortality and macrophage activation syndrome in adult onset Still's disease. Analysis of the multicentre Gruppo Italiano di Ricerca in Reumatologia Clinica e Sperimentale (GIRRCS) cohort

scientific article published on 09 July 2020

Glucocorticoids in rheumatoid arthritis: the silent companion in the therapeutic strategy

scientific article published on 20 May 2020

Guidelines for biomarkers in autoimmune rheumatic diseases - evidence based analysis

scientific article published on 05 November 2018

H-ferritin and CD68(+) /H-ferritin(+) monocytes/macrophages are increased in the skin of adult-onset Still's disease patients and correlate with the multi-visceral involvement of the disease.

scientific article published on 18 June 2016

H-ferritin and proinflammatory cytokines are increased in the bone marrow of patients affected by macrophage activation syndrome.

scientific article published on 28 September 2017

Haematopoietic stem cell transplantation in systemic sclerosis: Challenges and perspectives

scientific article published on 14 September 2020

Hyaluronic acid and platelet-rich plasma, a new therapeutic alternative for scleroderma patients: a prospective open-label study

scientific article published on 13 December 2019

IL-1 inhibition improves insulin resistance and adipokines in rheumatoid arthritis patients with comorbid type 2 diabetes: An observational study

scientific article published on 01 February 2019

IL-1β at the crossroad between rheumatoid arthritis and type 2 diabetes: may we kill two birds with one stone?

scientific article

IL-25 axis is involved in the pathogenesis of human primary and experimental Sjögren's syndrome.

scientific article published on 23 March 2018

Impaired Cav-1 expression in SSc mesenchymal cells upregulates VEGF signaling: a link between vascular involvement and fibrosis

scientific article

Impaired endothelium-mesenchymal stem cells cross-talk in systemic sclerosis: a link between vascular and fibrotic features

scientific article

Incidence, prevalence and mortality of systemic sclerosis in Italy: a nationwide population-based study using administrative health data

scientific article published on 14 October 2020

Increased Cardiovascular Events and Subclinical Atherosclerosis in Rheumatoid Arthritis Patients: 1 Year Prospective Single Centre Study

scientific article

Increased level of H-ferritin and its imbalance with L-ferritin, in bone marrow and liver of patients with adult onset Still's disease, developing macrophage activation syndrome, correlate with the severity of the disease.

scientific article

Interleukin (IL)-9/IL-9R axis drives γδ T cells activation in psoriatic arthritis patients

scientific article published on 20 August 2016

Interleukin-32 in systemic sclerosis, a potential new biomarker for pulmonary arterial hypertension

scientific article published on 01 June 2020

Interleukin-9 Overexpression and Th9 Polarization Characterize the Inflamed Gut, the Synovial Tissue, and the Peripheral Blood of Patients With Psoriatic Arthritis

scientific article published on 01 August 2016

Interleukin-9 over-expression and T helper 9 polarization in systemic sclerosis patients.

scientific article

International consensus: What else can we do to improve diagnosis and therapeutic strategies in patients affected by autoimmune rheumatic diseases (rheumatoid arthritis, spondyloarthritides, systemic sclerosis, systemic lupus erythematosus, antiphos

scientific article

Interstitial lung disease in systemic sclerosis: current and future treatment

scientific article published on 6 January 2017

Is minor salivary gland biopsy more than a diagnostic tool in primary Sjo¨gren׳s syndrome? Association between clinical, histopathological, and molecular features: A retrospective study

scientific article published on 15 May 2014

Jejunoileal bypass as the main procedure in the onset of immune-related conditions: the model of BADAS.

scientific article published on May 2013

Laboratory assessment in patients with suspected rheumatic musculoskeletal diseases: challenges, pitfalls and perspectives

scientific article published on 19 March 2018

Linking myofibroblast generation and microvascular alteration: The role of CD248 from pathogenesis to therapeutic target (Review)

scientific article published on 26 June 2019

Long-Term Retention Rate of Anakinra in Adult Onset Still's Disease and Predictive Factors for Treatment Response

scientific article published on 02 April 2019

Low-Dose Aspirin as Primary Prophylaxis for Cardiovascular Events in Rheumatoid Arthritis: An Italian Multicentre Retrospective Study.

scientific article published on 2 May 2019

Lung involvement in macrophage activation syndrome and severe COVID-19: results from a cross-sectional study to assess clinical, laboratory and artificial intelligence-radiological differences

scientific article published on 21 July 2020

Macitentan inhibits the transforming growth factor-β profibrotic action, blocking the signaling mediated by the ETR/TβRI complex in systemic sclerosis dermal fibroblasts.

scientific article

Macrophage Activation Syndrome in Patients Affected by Adult-onset Still Disease: Analysis of Survival Rates and Predictive Factors in the Gruppo Italiano di Ricerca in Reumatologia Clinica e Sperimentale Cohort

scientific article published on 15 April 2018

Macrophage activation syndrome in Still's disease: analysis of clinical characteristics and survival in paediatric and adult patients.

scientific article published on 15 September 2017

Macrophages with regulatory functions, a possible new therapeutic perspective in autoimmune diseases

scientific article published on 09 August 2019

Managing Adult-onset Still's disease: The effectiveness of high-dosage of corticosteroids as first-line treatment in inducing the clinical remission. Results from an observational study

Mediterranean diet and Psoriatic Arthritis activity: a multicenter cross-sectional study

scientific article published on 11 October 2019

Mesenchymal stem cells of Systemic Sclerosis patients, derived from different sources, show a profibrotic microRNA profiling

scientific article published on 09 May 2019

Mesenchymal stromal cells and rheumatic diseases: new tools from pathogenesis to regenerative therapies.

scientific article

Metabolic Syndrome and psoriatic arthritis: considerations for the clinician

scientific article published on 01 April 2020

Methotrexate in rheumatoid arthritis: optimizing therapy among different formulations. Current and emerging paradigms.

scientific article

Methotrexate: an old new drug in autoimmune disease.

scientific article published on 22 September 2014

Monocytes from patients with rheumatoid arthritis and type 2 diabetes mellitus display an increased production of interleukin (IL)-1β via the nucleotide-binding domain and leucine-rich repeat containing family pyrin 3(NLRP3)-inflammasome activation:

scientific article published on 10 June 2015

Oxidized low density lipoproteins: The bridge between atherosclerosis and autoimmunity. Possible implications in accelerated atherosclerosis and for immune intervention in autoimmune rheumatic disorders

scientific article published on 6 February 2018

Parenchymal lung disease in adult onset Still's disease: an emergent marker of disease severity-characterisation and predictive factors from Gruppo Italiano di Ricerca in Reumatologia Clinica e Sperimentale (GIRRCS) cohort of patients

scientific article published on 22 June 2020

Pathogenesis of adult onset Still's disease: current understanding and new insights

scientific article published on 12 October 2018

Perivascular Cells in Diffuse Cutaneous Systemic Sclerosis Overexpress Activated ADAM12 and Are Involved in Myofibroblast Transdifferentiation and Development of Fibrosis.

scientific article published in June 2016

Persistence of focal lymphocytic sialadenitis in patients with primary Sjögren's syndrome treated with rituximab: a possible role for glandular BAFF.

scientific article published on 2 August 2016

Pharmacological stress, rest perfusion and delayed enhancement cardiac magnetic resonance identifies very early cardiac involvement in systemic sclerosis patients of recent onset.

scientific article published on 4 June 2017

Poor clinical response in rheumatoid arthritis is the main risk factor for diabetes development in the short-term: A 1-year, single-centre, longitudinal study.

scientific article

Potential of stem cells in the treatment of rheumatic disease

Prescribing motivations and patients' characteristics related to the use of biologic drugs in adult-onset Still's disease: analysis of a multicentre "real-life" cohort

scientific article published on 01 July 2019

Prevalence of type 2 diabetes and impaired fasting glucose in patients affected by rheumatoid arthritis: Results from a cross-sectional study.

scientific article

Pro-inflammatory properties of H-ferritin on human macrophages, ex vivo and in vitro observations

scientific article published on 22 July 2020

Prognostic factors of macrophage activation syndrome, at the time of diagnosis, in adult patients affected by autoimmune disease: Analysis of 41 cases collected in 2 rheumatologic centers.

scientific article published on 21 September 2016

Quality of life and unmet needs in patients with inflammatory arthropathies: results from the multicentre, observational RAPSODIA study

scientific article published on 6 October 2014

Response to Interleukin-1 Inhibitors in 140 Italian Patients with Adult-Onset Still's Disease: A Multicentre Retrospective Observational Study

scientific article

Response to: 'Correspondence on 'Changing the outcome measures, changing the results? The urgent need of a specific disease activity score to adult-onset Still's disease'' by Muraviov and Muraviova

scientific article published on 28 September 2020

Response to: 'Correspondence on 'Lung involvement in macrophage activation syndrome and severe COVID-19: results from a cross-sectional study to assess clinical, laboratory and artificial intelligence-radiological differences' by Ruscitti et al' by

scientific article published on 09 September 2020

Role of Colchicine Treatment in Tumor Necrosis Factor Receptor Associated Periodic Syndrome (TRAPS): Real-Life Data from the AIDA Network

scientific article published on 27 May 2020

Safety and efficacy of intra-articular anti-tumor necrosis factor α agents compared to corticosteroids in a treat-to-target strategy in patients with inflammatory arthritis and monoarthritis flare

scientific article published on 18 December 2015

Scleroderma Mesenchymal Stem Cells display a different phenotype from healthy controls; implications for regenerative medicine

scientific article

Searching for a good model for systemic sclerosis: the molecular profile and vascular changes occurring in UCD-200 chickens strongly resemble the early phase of human systemic sclerosis

scientific article published on July 2016

Severe COVID-19 and related hyperferritinaemia: more than an innocent bystander?

scientific article published on 20 May 2020

Severe COVID-19, Another Piece in the Puzzle of the Hyperferritinemic Syndrome. An Immunomodulatory Perspective to Alleviate the Storm

scientific article published on 28 May 2020

Stem cell therapies for systemic sclerosis.

scientific article

Subclinical and clinical atherosclerosis in rheumatoid arthritis: results from the 3-year, multicentre, prospective, observational GIRRCS (Gruppo Italiano di Ricerca in Reumatologia Clinica e Sperimentale) study

scientific article published on 03 September 2019

Subclinical atherosclerosis and history of cardiovascular events in Italian patients with rheumatoid arthritis: Results from a cross-sectional, multicenter GIRRCS (Gruppo Italiano di Ricerca in Reumatologia Clinica e Sperimentale) study

scientific article published in October 2017

T helper 1 response is correlated with widespread pain, fatigue, sleeping disorders and the quality of life in patients with fibromyalgia and is modulated by hyperbaric oxygen therapy

scientific article published on 01 January 2019

Targeted synthetic pharmacotherapy for psoriatic arthritis: state of the art

scientific article published on 14 February 2020

The CD68(+)/H-ferritin(+) cells colonize the lymph nodes of the patients with adult onset Still's disease and are associated with increased extracellular level of H-ferritin in the same tissue: correlation with disease severity and implication for p

scientific article published on 5 November 2015

The Endothelial-mesenchymal Transition in Systemic Sclerosis Is Induced by Endothelin-1 and Transforming Growth Factor-β and May Be Blocked by Macitentan, a Dual Endothelin-1 Receptor Antagonist

scientific article published on 15 August 2015

The Vessels Contribute to Fibrosis in Systemic Sclerosis

scientific article published on 01 July 2019

The effect of non-TNF-targeted biologics and small molecules on insulin resistance in inflammatory arthritis

scientific article published on 13 February 2018

The effect of non-TNF-targeted biologics on vascular dysfunction in rheumatoid arthritis: A systematic literature review

scientific article published on 04 March 2019

The emerging role of IL-1 inhibition in patients affected by rheumatoid arthritis and diabetes

scientific article published on 13 March 2018

The reduction of concomitant glucocorticoids dosage following treatment with IL-1 receptor antagonist in adult onset Still's disease. A systematic review and meta-analysis of observational studies

scientific article published on 17 June 2020

The role of IL-1β in the bone loss during rheumatic diseases.

scientific article published on 12 April 2015

The role of extracellular matrix components in angiogenesis and fibrosis: Possible implication for systemic sclerosis

scientific article published on 19 January 2018

The treatment of adult-onset Still's disease with anakinra, a recombinant human IL-1 receptor antagonist: a systematic review of literature

scientific article published on 12 May 2020

Tocilizumab for the treatment of adult-onset Still's disease: results from a case series.

scientific article published on 5 September 2013

Unique expansion of IL-21+ Tfh and Tph cells under control of ICOS identifies Sjögren's syndrome with ectopic germinal centres and MALT lymphoma

scientific article published on 22 September 2020

Vitamin D increases the production of IL-10 by regulatory T cells in patients with systemic sclerosis

scientific article published on 01 July 2019

What could we learn from the sub-analysis of a single nation cohort in a worldwide study? Lessons from the results observed in the Italian cohort of the GO-MORE trial

scientific article published on 6 June 2017