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List of works by Tomohide Tsukahara

A novel CIC-FOXO4 gene fusion in undifferentiated small round cell sarcoma: a genetically distinct variant of Ewing-like sarcoma

scientific article published on 01 November 2014

A novel nuclear DnaJ protein, DNAJC8, can suppress the formation of spinocerebellar ataxia 3 polyglutamine aggregation in a J-domain independent manner.

scientific article

A quest for therapeutic antigens in bone and soft tissue sarcoma

scientific article

ABCG2 expression is related to low 5-ALA photodynamic diagnosis (PDD) efficacy and cancer stem cell phenotype, and suppression of ABCG2 improves the efficacy of PDD.

scientific article published on 13 May 2019

Aberrant expression and potency as a cancer immunotherapy target of inhibitor of apoptosis protein family, Livin/ML-IAP in lung cancer.

scientific article published on February 2005

Autologous CTL response against cancer stem‐like cells/cancer‐initiating cells of bone malignant fibrous histiocytoma ⬇️

scientific article published on May 31, 2011

Borderline Microenvironment Fibrosis Is a Novel Poor Prognostic Marker of Oral Squamous Cell Carcinoma

scientific article published on 01 August 2020

Brother of the regulator of the imprinted site (BORIS) variant subfamily 6 is a novel target of lung cancer stem-like cell immunotherapy

scientific article

Cancer immunotherapy and immunological memory

scientific article published on January 2016

Cancer-Associated Oxidase ERO1-α Regulates the Expression of MHC Class I Molecule via Oxidative Folding

scientific article

Cancer-associated oxidoreductase ERO1-α drives the production of VEGF via oxidative protein folding and regulating the mRNA level

scientific article published on 21 April 2016

Cancer-associated oxidoreductase ERO1-α promotes immune escape through up-regulation of PD-L1 in human breast cancer

scientific article

Case report: Long-term survival of a pancreatic cancer patient immunized with an SVN-2B peptide vaccine

scholarly article by Hiroaki Shima et al published 1 August 2018 in Cancer Immunology, Immunotherapy

Cellular stress induces cancer stem-like cells through expression of DNAJB8 by activation of HSF1.

scientific article published on 8 January 2018

Clonal T-cell response against autologous pleomorphic malignant fibrous histiocytoma antigen presented by retrieved HLA-A*0206.

scientific article published on February 2008

Clonal analysis revealed functional heterogeneity in cancer stem-like cell phenotypes in uterine endometrioid adenocarcinoma

scientific article published on 30 November 2018

CpG-A stimulates Hsp72 secretion from plasmacytoid dendritic cells, facilitating cross-presentation

scientific article published on 30 June 2015

Crisscross CTL induction by SYT-SSX junction peptide and its HLA-A*2402 anchor substitute

scientific article published on July 2004

Detection and induction of CTLs specific for SYT-SSX-derived peptides in HLA-A24(+) patients with synovial sarcoma

scientific article

Development of a TCR multimer with high avidity for detecting a naturally presented tumor-associated antigen on osteosarcoma cells

article

Development of an artificial antibody specific for HLA/peptide complex derived from cancer stem-like cell/cancer-initiating cell antigen DNAJB8

scientific article published on 05 August 2020

Development of next-generation peptide vaccination therapy

scientific article published on 01 February 2017

Diagnostic utility of NCOA2 fluorescence in situ hybridization and Stat6 immunohistochemistry staining for soft tissue angiofibroma and morphologically similar fibrovascular tumors

scientific article

Differential bronchial epithelial response regulated by ΔNp63: a functional understanding of the epithelial shedding found in asthma

scientific article published on 25 September 2018

ECRG4 is a negative regulator of caspase-8-mediated apoptosis in human T-leukemia cells ⬇️

scientific article published on March 12, 2012

Ectopically expressed variant form of sperm mitochondria-associated cysteine-rich protein augments tumorigenicity of the stem cell population of lung adenocarcinoma cells

scientific article

Establishment and Analysis of Cancer Stem-Like and Non-Cancer Stem-Like Clone Cells from the Human Colon Cancer Cell Line SW480

scientific article

Fatal fulminant hepatitis induced by combined ipilimumab and nivolumab therapy despite favorable histologic response and confirmed by autopsy in a patient with clear cell renal cell carcinoma

scientific article published on 07 July 2020

GRIK2 has a role in the maintenance of urothelial carcinoma stem-like cells, and its expression is associated with poorer prognosis

scientific article

HLA-A*0201-restricted CTL epitope of a novel osteosarcoma antigen, papillomavirus binding factor

scientific article

HLA-A24 ligandome analysis of colon and lung cancer cells identifies a novel cancer-testis antigen and a neoantigen that elicits specific and strong CTL responses

scientific article published on 16 February 2017

HLA-restricted specific tumor cytolysis by autologous T-lymphocytes infiltrating metastatic bone malignant fibrous histiocytoma of lymph node

scientific article published on January 2006

Heat shock enhances the expression of cytotoxic granule proteins and augments the activities of tumor-associated antigen-specific cytotoxic T lymphocytes

scientific article

Heat shock protein 90 targets a chaperoned peptide to the static early endosome for efficient cross-presentation by human dendritic cells

scientific article published on 15 December 2014

Heat shock protein DNAJB8 is a novel target for immunotherapy of colon cancer-initiating cells

scientific article

High expression of CD109 antigen regulates the phenotype of cancer stem-like cells/cancer-initiating cells in the novel epithelioid sarcoma cell line ESX and is related to poor prognosis of soft tissue sarcoma

scientific article published in 2013

Hypoxia augments MHC class I antigen presentation via facilitation of ERO1-α-mediated oxidative folding in murine tumor cells

scientific article published on 26 September 2016

Identification and functional analysis of variants of a cancer/testis antigen LEMD1 in colorectal cancer stem-like cells

scientific article published on 17 February 2017

Identification of CLUAP1 as a human osteosarcoma tumor-associated antigen recognized by the humoral immune system

scientific article

Identification of a novel human memory T-cell population with the characteristics of stem-like chemo-resistance

scientific article published on 8 June 2016

Identification of cancer-stem cell antigens and development of CTL-mediated cancer immunotherapy

scientific article

Identification of human autologous cytotoxic T-lymphocyte-defined osteosarcoma gene that encodes a transcriptional regulator, papillomavirus binding factor

scientific article published in August 2004

Identification of novel human leukocyte antigen-A*11:01-restricted cytotoxic T-lymphocyte epitopes derived from osteosarcoma antigen papillomavirus binding factor

scientific article published on 12 March 2019

Immune responses to human cancer stem-like cells/cancer-initiating cells

scientific article

Immunogenic enhancement and clinical effect by type-I interferon of anti-apoptotic protein, survivin-derived peptide vaccine, in advanced colorectal cancer patients

scientific article published on 24 April 2011

Immunohistological analysis of pancreatic carcinoma after vaccination with survivin 2B peptide: Analysis of an autopsy series

scientific article published on 11 July 2019

Immunotherapeutic benefit of α-interferon (IFNα) in survivin2B-derived peptide vaccination for advanced pancreatic cancer patients

scientific article published on 16 December 2012

Implication of chemo-resistant memory T cells for immune surveillance in patients with sarcoma receiving chemotherapy.

scientific article published on 12 July 2017

Improved generation of HLA class I/peptide tetramers

scientific article

LY6/PLAUR domain containing 3 has a role in the maintenance of colorectal cancer stem-like cells

scientific article published on 23 February 2017

Less correlation between mismatch repair proteins deficiency and decreased expression of HLA class I molecules in endometrial carcinoma: a different propensity from colorectal cancer

scientific article published on 14 May 2020

Loss of tapasin in human lung and colon cancer cells and escape from tumor-associated antigen-specific CTL recognition

scientific article published on 3 January 2017

MAPK13 is preferentially expressed in gynecological cancer stem cells and has a role in the tumor-initiation

scientific article published on 08 March 2016

Mismatch Repair Protein Deficiency Is a Risk Factor for Aberrant Expression of HLA Class I Molecules: A Putative "Adaptive Immune Escape" Phenomenon

scientific article published in March 2017

Molecular pathological approaches to human tumor immunology

scientific article published on April 2009

Multimodality assessment of spontaneous haemostasis of left ventricular free wall rupture after myocardial infarction

scientific article published on 27 January 2016

NK/T-cell lymphoma of bilateral adrenal glands in a patient with pyothorax ⬇️

scientific article published on August 29, 2012

Non-bacterial cystitis with increased expression of programmed death-ligand 1 in the urothelium: An unusual immune-related adverse event during treatment with pembrolizumab for lung adenocarcinoma

scientific article published on 12 August 2020

Olfactory Receptor Family 7 Subfamily C Member 1 Is a Novel Marker of Colon Cancer-Initiating Cells and Is a Potent Target of Immunotherapy

scientific article published on 9 February 2016

Osteosarcoma-initiating cells show high aerobic glycolysis and attenuation of oxidative phosphorylation mediated by LIN28B

scientific article published on 29 November 2019

Overexpression of papillomavirus binding factor in Ewing's sarcoma family of tumors conferring poor prognosis.

scientific article published in January 2008

Peptide vaccination therapy: Towards the next generation

scientific article

Peptide vaccinations elicited strong immune responses that were reboosted by anti-PD1 therapy in a patient with myxofibrosarcoma

scientific article published on 18 December 2019

Phase I vaccination trial of SYT-SSX junction peptide in patients with disseminated synovial sarcoma

scientific article

Phosphorylation of HSF1 at serine 326 residue is related to the maintenance of gynecologic cancer stem cells through expression of HSP27.

scientific article published on 18 March 2017

Plasticity of lung cancer stem-like cells is regulated by the transcription factor HOXA5 that is induced by oxidative stress.

scientific article published on 13 July 2016

Probabilistic modeling of personalized drug combinations from integrated chemical screen and molecular data in sarcoma

scientific article published on 17 June 2019

Prognostic impact and immunogenicity of a novel osteosarcoma antigen, papillomavirus binding factor, in patients with osteosarcoma

scientific article published on February 2008

Prognostic impact of CD109 expression in myxofibrosarcoma

scientific article published on 28 May 2015

Prognostic significance of HLA class I expression in Ewing's sarcoma family of tumors ⬇️

scientific article published on December 28, 2010

Prognostic significance of HLA class I expression in osteosarcoma defined by anti-pan HLA class I monoclonal antibody, EMR8-5

scientific article published on 21 September 2006

Prognostic value of HLA class Ⅰ expression in patients with oral squamous cell carcinoma

scientific article published on 13 March 2020

Randomized phase II trial of survivin 2B peptide vaccination for patients with HLA-A24-positive pancreatic adenocarcinoma

scientific article published on 23 July 2019

Recognition by cellular and humoral autologous immunity in a human osteosarcoma cell line

scientific article

ST6GALNAC1 plays important roles in enhancing cancer stem phenotypes of colorectal cancer via the Akt pathway

scientific article published on 8 November 2017

SYT‐SSX breakpoint peptide vaccines in patients with synovial sarcoma: A study from the Japanese Musculoskeletal Oncology Group ⬇️

scientific article published on 07 August 2012

Scythe/BAT3 regulates apoptotic cell death induced by papillomavirus binding factor in human osteosarcoma

scientific article

Simultaneous radial closing wedge and ulnar shortening osteotomies for distal radius malunion

scientific article published in March 2004

Small proline-rich protein-1B is overexpressed in human oral squamous cell cancer stem-like cells and is related to their growth through activation of MAP kinase signal

scientific article published on 13 August 2013

Spatiotemporal metabolic dynamics of the photosensitizer talaporfin sodium in carcinoma and sarcoma

scientific article published on 15 November 2020

Specific targeting of a naturally presented osteosarcoma antigen, papillomavirus binding factor peptide, using an artificial monoclonal antibody

scientific article

The antigen ASB4 on cancer stem cells serves as a target for CTL immunotherapy of colorectal cancer

scientific article published on 25 January 2018

The future of immunotherapy for sarcoma

scientific article published on 9 May 2016

[Peptide vaccination therapy for bone and soft tissue sarcoma]

scientific article published on 01 September 2011

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