List of works - Ewa Surmiak

A Unique Mdm2-Binding Mode of the 3-Pyrrolin-2-one- and 2-Furanone-Based Antagonists of the p53-Mdm2 Interaction

scientific article

A fluorinated indole-based MDM2 antagonist selectively inhibits the growth of p53wt osteosarcoma cells

scientific article published on 16 February 2019

A therapeutic patent overview of MDM2/X-targeted therapies (2014-2018)

scientific article published on 01 March 2019

Biphenyl Ether Analogs Containing Pomalidomide as Small-Molecule Inhibitors of the Programmed Cell Death-1/Programmed Cell Death-Ligand 1 Interaction

scientific article published on 27 May 2022

Comparison of the Hydrogen Bond Interaction Dynamics in the Guanine and Cytosine Crystals: Ab Initio Molecular Dynamics and Spectroscopic Study

scientific article published on 05 December 2019

Computer- and NMR-aided design of small-molecule inhibitors of the Hub1 protein

scientific article published on 27 January 2022

Design of indole- and MCR-based macrocycles as p53-MDM2 antagonists

scientific article published on 20 February 2019

Design, Synthesis, and Biological Evaluation of Imidazopyridines as PD-1/PD-L1 Antagonists

scientific article published on 28 April 2021

Helping the Released Guardian: Drug Combinations for Supporting the Anticancer Activity of HDM2 (MDM2) Antagonists

scientific article published on 19 July 2019

Hitting on the move: Targeting intrinsically disordered protein states of the MDM2-p53 interaction

scientific article published on 06 August 2019

NMR fragment-based screening for development of the CD44-binding small molecules

scientific article published on 25 October 2018

PD-L1 Inhibitors: Different Classes, Activities, and Mechanisms of Action

scientific article published on 30 October 2021

Rational design and synthesis of 1,5-disubstituted tetrazoles as potent inhibitors of the MDM2-p53 interaction.

scientific article published on 16 November 2016

Terphenyl-Based Small-Molecule Inhibitors of Programmed Cell Death-1/Programmed Death-Ligand 1 Protein-Protein Interaction

scientific article published on 12 August 2021

Terphenyl-based Small-Molecule Inhibitors of Programmed Cell Death-1/Programmed Death-Ligand 1 Protein−Protein Interaction

scientific article published on 11 February 2021

Terphenyl-based Small-Molecule Inhibitors of Programmed Cell Death-1/Programmed Death-Ligand 1 Protein−Protein Interaction

scientific article

The synthesis and characterization of tetramic acid derivatives as Mdm2-p53 inhibitors

scientific article published in August 2019

List of works by Ewa Surmiak

A Unique Mdm2-Binding Mode of the 3-Pyrrolin-2-one- and 2-Furanone-Based Antagonists of the p53-Mdm2 Interaction

A fluorinated indole-based MDM2 antagonist selectively inhibits the growth of p53wt osteosarcoma cells

A therapeutic patent overview of MDM2/X-targeted therapies (2014-2018)

Biphenyl Ether Analogs Containing Pomalidomide as Small-Molecule Inhibitors of the Programmed Cell Death-1/Programmed Cell Death-Ligand 1 Interaction

Comparison of the Hydrogen Bond Interaction Dynamics in the Guanine and Cytosine Crystals: Ab Initio Molecular Dynamics and Spectroscopic Study

Computer- and NMR-aided design of small-molecule inhibitors of the Hub1 protein

Design of indole- and MCR-based macrocycles as p53-MDM2 antagonists

Design, Synthesis, and Biological Evaluation of Imidazopyridines as PD-1/PD-L1 Antagonists

Helping the Released Guardian: Drug Combinations for Supporting the Anticancer Activity of HDM2 (MDM2) Antagonists

Hitting on the move: Targeting intrinsically disordered protein states of the MDM2-p53 interaction

NMR fragment-based screening for development of the CD44-binding small molecules

PD-L1 Inhibitors: Different Classes, Activities, and Mechanisms of Action

Rational design and synthesis of 1,5-disubstituted tetrazoles as potent inhibitors of the MDM2-p53 interaction.

Terphenyl-Based Small-Molecule Inhibitors of Programmed Cell Death-1/Programmed Death-Ligand 1 Protein-Protein Interaction

Terphenyl-based Small-Molecule Inhibitors of Programmed Cell Death-1/Programmed Death-Ligand 1 Protein−Protein Interaction

Terphenyl-based Small-Molecule Inhibitors of Programmed Cell Death-1/Programmed Death-Ligand 1 Protein−Protein Interaction

The synthesis and characterization of tetramic acid derivatives as Mdm2-p53 inhibitors