List of works - Oliver Kudlacek

A two-state model for the diffusion of the A2A adenosine receptor in hippocampal neurons: agonist-induced switch to slow mobility is modified by synapse-associated protein 102 (SAP102)

scientific article published on 7 February 2014

ABC transporters of Fasciola hepatica as putative drug targets

scientific article published on 5 September 2011

ABC transporters of the liver fluke

ARNO/cytohesin-2 regulates desensitization of the Aadenosine receptor in rat pheochromocytoma cells

Aadenosine receptor interacting partners (interactome)

scientific article published on 12 November 2009

Activation and inhibition of G proteins by lipoamines

scientific article published in March 2002

Aminorex, a metabolite of the cocaine adulterant levamisole, exerts amphetamine like actions at monoamine transporters

scientific article published on December 2013

Amphetamine action at the cocaine- and antidepressant-sensitive serotonin transporter is modulated by αCaMKII.

scientific article published on May 2015

Amphetamine actions at the serotonin transporter rely on the availability of phosphatidylinositol-4,5-bisphosphate

scientific article published on 24 June 2013

Amphetamines take two to tango: an oligomer-based counter-transport model of neurotransmitter transport explores the amphetamine action

An unsuspected role for organic cation transporter 3 in the actions of amphetamine

scientific article published on 06 April 2018

Biased inhibition by a suramin analogue of A1-adenosine receptor/G protein coupling in fused receptor/G protein tandems: the A1-adenosine receptor is predominantly coupled to Goalpha in human brain.

scientific article published on 7 November 2001

Ca(2+)/calmodulin-dependent protein kinase IIα (αCaMKII) controls the activity of the dopamine transporter: implications for Angelman syndrome.

scientific article published on 9 July 2012

Calmodulin kinase II regulates amphetamine-induced reverse transport in dopamine and serotonin transporters

scientific article published on 17 September 2012

Calmodulin kinase II regulates amphetamine-induced reverse transport in the dopamine transporter: implications for the importance of the dopamine transporter in Angelman syndrome.

scientific article

Cocaine adulteration

scientific article

Combined Simulation and Mutation Studies to Elucidate Selectivity of Unsubstituted Amphetamine-like Cathinones at the Dopamine Transporter

scientific article published on 8 November 2016

Consequences of loss of PINCH2 expression in mice

scientific article

Decrypting structural and functional changes in LeuTAa at atomic level employing LRET

Development of Gs-selective inhibitory compounds.

scientific article

Direct PIP2 binding mediates stable oligomer formation of the serotonin transporter

scientific article published on 19 January 2017

Dopamine transporter forms stable dimers in the live cell plasma membrane in a phosphatidylinositol 4,5-bisphosphate-independent manner

scientific article published on 31 January 2019

Fluorescence resonance energy transfer (FRET) sensors

ILK, PINCH and parvin: the tIPP of integrin signalling

scientific article

Identification and characterization of the Fasciola hepatica sodium- and chloride-dependent taurine transporter.

scientific article published on 27 April 2018

Identification of an additional interaction domain in transmembrane domains 11 and 12 that supports oligomer formation in the human serotonin transporter.

scientific article

Importance of the carboxyl terminus for folding and trafficking of the serotonin transporter

scientific article published on 12 November 2009

In vivo amphetamine action is contingent on αCaMKII

scientific article

Interaction between fast and ultra-slow inactivation in the voltage-gated sodium channel. Does the inactivation gate stabilize the channel structure?

scientific article published on 23 July 2002

Jak1 deficiency leads to enhanced Abelson-induced B-cell tumor formation

scientific article published on 06 February 2003

MAP kinase stimulation by cAMP does not require RAP1 but SRC family kinases

scientific article

Mechanism of hERG channel block by the psychoactive indole alkaloid ibogaine.

scientific article published on 4 December 2013

Mig6 is a negative regulator of EGF receptor-mediated skin morphogenesis and tumor formation

scientific journal article

Mutational analysis of the high-affinity zinc binding site validates a refined human dopamine transporter homology model

scientific article

Mutations in the amino-terminus impair amphetamine-induced efflux by inducing inward-facing conformations of the serotonin transporter

scholarly article by Sonja Sucic et al published 2009 in BMC Pharmacology

Mutations in the carboxyl-terminal SEC24 binding motif of the serotonin transporter impair folding of the transporter.

scientific article published on 2 October 2010

Nanopharmacological Force Sensing to Reveal Allosteric Coupling in Transporter Binding Sites

scientific article published on 22 December 2015

PINCH1 regulates cell-matrix and cell-cell adhesions, cell polarity and cell survival during the peri-implantation stage

scientific journal article

Recruitment of a cytoplasmic chaperone relay by the A2A adenosine receptor.

scientific article published on 21 August 2013

Restricted collision coupling of the A2A receptor revisited: evidence for physical separation of two signaling cascades

scientific article published on 24 January 2008

Selectivity filter residues contribute unequally to pore stabilization in voltage-gated sodium channels

scientific article published on 01 October 2005

Single molecule analysis reveals coexistence of stable serotonin transporter monomers and oligomers in the live cell plasma membrane.

scientific article published on 06 January 2014

Structure and regulatory interactions of the cytoplasmic terminal domains of serotonin transporter.

scientific article

Switching the clientele: a lysine residing in the C terminus of the serotonin transporter specifies its preference for the coat protein complex II component SEC24C

scientific article published on 3 January 2013

The N terminus of monoamine transporters is a lever required for the action of amphetamines

scientific article

The folding interactome of GPCRs

The human D2 dopamine receptor synergizes with the A2A adenosine receptor to stimulate adenylyl cyclase in PC12 cells.

scientific article

The interactome of the A2A adenosine receptor in vitro and in vivo.

scientific article

The presence of phosphatidylinositol-4,5-bisphosphate directly impacts on amphetamine-induced serotonin transporter-mediated efflux

The role of the carboxyl terminus in folding of the serotonin transporter.

scientific article

The serotonin transporter is an exclusive client of the coat protein complex II (COPII) component SEC24C.

scientific article

Truncations in the amino terminus reveal a region key to supporting amphetamine-induced efflux by the human serotonin transporter

scholarly article by Sonja Sucic et al published 2011 in BMC Pharmacology

Two discontinuous segments in the carboxyl terminus are required for membrane targeting of the rat gamma-aminobutyric acid transporter-1 (GAT1)

scientific journal article

List of works by Oliver Kudlacek

A two-state model for the diffusion of the A2A adenosine receptor in hippocampal neurons: agonist-induced switch to slow mobility is modified by synapse-associated protein 102 (SAP102)

ABC transporters of Fasciola hepatica as putative drug targets

ABC transporters of the liver fluke

ARNO/cytohesin-2 regulates desensitization of the Aadenosine receptor in rat pheochromocytoma cells

Aadenosine receptor interacting partners (interactome)

Activation and inhibition of G proteins by lipoamines

Aminorex, a metabolite of the cocaine adulterant levamisole, exerts amphetamine like actions at monoamine transporters

Amphetamine action at the cocaine- and antidepressant-sensitive serotonin transporter is modulated by αCaMKII.

Amphetamine actions at the serotonin transporter rely on the availability of phosphatidylinositol-4,5-bisphosphate

Amphetamines take two to tango: an oligomer-based counter-transport model of neurotransmitter transport explores the amphetamine action

An unsuspected role for organic cation transporter 3 in the actions of amphetamine

Biased inhibition by a suramin analogue of A1-adenosine receptor/G protein coupling in fused receptor/G protein tandems: the A1-adenosine receptor is predominantly coupled to Goalpha in human brain.

Ca(2+)/calmodulin-dependent protein kinase IIα (αCaMKII) controls the activity of the dopamine transporter: implications for Angelman syndrome.

Calmodulin kinase II regulates amphetamine-induced reverse transport in dopamine and serotonin transporters

Calmodulin kinase II regulates amphetamine-induced reverse transport in the dopamine transporter: implications for the importance of the dopamine transporter in Angelman syndrome.

Cocaine adulteration

Combined Simulation and Mutation Studies to Elucidate Selectivity of Unsubstituted Amphetamine-like Cathinones at the Dopamine Transporter

Consequences of loss of PINCH2 expression in mice

Decrypting structural and functional changes in LeuTAa at atomic level employing LRET

Development of Gs-selective inhibitory compounds.

Direct PIP2 binding mediates stable oligomer formation of the serotonin transporter

Dopamine transporter forms stable dimers in the live cell plasma membrane in a phosphatidylinositol 4,5-bisphosphate-independent manner

Fluorescence resonance energy transfer (FRET) sensors

ILK, PINCH and parvin: the tIPP of integrin signalling

Identification and characterization of the Fasciola hepatica sodium- and chloride-dependent taurine transporter.

Identification of an additional interaction domain in transmembrane domains 11 and 12 that supports oligomer formation in the human serotonin transporter.

Importance of the carboxyl terminus for folding and trafficking of the serotonin transporter

In vivo amphetamine action is contingent on αCaMKII

Interaction between fast and ultra-slow inactivation in the voltage-gated sodium channel. Does the inactivation gate stabilize the channel structure?

Jak1 deficiency leads to enhanced Abelson-induced B-cell tumor formation

MAP kinase stimulation by cAMP does not require RAP1 but SRC family kinases

Mechanism of hERG channel block by the psychoactive indole alkaloid ibogaine.

Mig6 is a negative regulator of EGF receptor-mediated skin morphogenesis and tumor formation

Mutational analysis of the high-affinity zinc binding site validates a refined human dopamine transporter homology model

Mutations in the amino-terminus impair amphetamine-induced efflux by inducing inward-facing conformations of the serotonin transporter

Mutations in the carboxyl-terminal SEC24 binding motif of the serotonin transporter impair folding of the transporter.

Nanopharmacological Force Sensing to Reveal Allosteric Coupling in Transporter Binding Sites

PINCH1 regulates cell-matrix and cell-cell adhesions, cell polarity and cell survival during the peri-implantation stage

Recruitment of a cytoplasmic chaperone relay by the A2A adenosine receptor.

Restricted collision coupling of the A2A receptor revisited: evidence for physical separation of two signaling cascades

Selectivity filter residues contribute unequally to pore stabilization in voltage-gated sodium channels

Single molecule analysis reveals coexistence of stable serotonin transporter monomers and oligomers in the live cell plasma membrane.

Structure and regulatory interactions of the cytoplasmic terminal domains of serotonin transporter.

Switching the clientele: a lysine residing in the C terminus of the serotonin transporter specifies its preference for the coat protein complex II component SEC24C

The N terminus of monoamine transporters is a lever required for the action of amphetamines

The folding interactome of GPCRs

The human D2 dopamine receptor synergizes with the A2A adenosine receptor to stimulate adenylyl cyclase in PC12 cells.

The interactome of the A2A adenosine receptor in vitro and in vivo.

The presence of phosphatidylinositol-4,5-bisphosphate directly impacts on amphetamine-induced serotonin transporter-mediated efflux

The role of the carboxyl terminus in folding of the serotonin transporter.

The serotonin transporter is an exclusive client of the coat protein complex II (COPII) component SEC24C.

Truncations in the amino terminus reveal a region key to supporting amphetamine-induced efflux by the human serotonin transporter

Two discontinuous segments in the carboxyl terminus are required for membrane targeting of the rat gamma-aminobutyric acid transporter-1 (GAT1)