List of works - Kathleen Sprouffske

Abstract 101: The mechanism of clonal expansion determines the tempo and mode of neoplastic progression in Barrett's esophagus

Accurate Reconstruction of the Temporal Order of Mutations in Neoplastic Progression ⬇️

scientific article published on April 13, 2011

An evolutionary explanation for the presence of cancer nonstem cells in neoplasms ⬇️

scientific article published on November 26, 2012

Animal Cell Differentiation Patterns Suppress Somatic Evolution

scientific article published on 01 November 2007

Animal cell differentiation patterns suppress somatic evolution

scientific article

Application of simultaneous selective pressures slows adaptation

scientific article published on 15 August 2020

Assessing the benefits of horizontal gene transfer by laboratory evolution and genome sequencing

scientific article published on 19 April 2018

Cancer in light of experimental evolution

scientific article (publication date: 11 September 2012)

Effect of Population Size and Mutation Rate on the Evolution of RNA Sequences on an Adaptive Landscape Determined by RNA Folding

scientific article published on 5 September 2017

Exquisite Sensitivity to Dual BRG1/BRM ATPase Inhibitors Reveals Broad SWI/SNF Dependencies in Acute Myeloid Leukemia

scientific article published in 2022

Genetic heterogeneity and clonal evolution during metastasis in breast cancer patient-derived tumor xenograft models

scientific article published on 31 January 2020

Growthcurver: an R package for obtaining interpretable metrics from microbial growth curves

scientific article published on 19 April 2016

High mutation rates limit evolutionary adaptation in Escherichia coli.

scientific article published on 27 April 2018

How Archiving by Freezing Affects the Genome-Scale Diversity of Escherichia coli Populations

scientific article

PAX8 activates metabolic genes via enhancer elements in Renal Cell Carcinoma

scientific article published on 20 August 2019

Peto's paradox revisited: theoretical evolutionary dynamics of cancer in wild populations

scientific article published on 22 November 2012

Protein destabilization underlies pathogenic missense mutations in ARID1B

scientific article published in 2024

Solving the Puzzle of Metastasis: The Evolution of Cell Migration in Neoplasms ⬇️

scientific article published on April 27, 2011

The discovery of SWI/SNF chromatin remodeling activity as a novel and targetable dependency in uveal melanoma

scientific article published on 03 August 2020

List of works by Kathleen Sprouffske