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List of works by Genichiro Ishii

A Minimum Of 100 Tumor Cells in a Single Biopsy Sample Is Required to Assess Programmed Cell Death Ligand 1 Expression in Predicting Patient Response to Nivolumab Treatment in Nonsquamous Non-Small Cell Lung Carcinoma

scientific article published on 28 June 2019

A novel histopathological evaluation method predicting the outcome of non-small cell lung cancer treated by neoadjuvant therapy: the prognostic importance of the area of residual tumor

scientific article published in January 2010

A novel method to generate single-cell-derived cancer-associated fibroblast clones

scientific article published on 31 March 2017

A resected case of sclerosing thymoma

scientific article published in May 2006

A secondary RET mutation in the activation loop conferring resistance to vandetanib.

scientific article published on 12 February 2018

Abundant tumor promoting stromal cells in lung adenocarcinoma with hypoxic regions

scientific article published on 20 November 2017

Adult neuroblastoma arising in the superior mediastinum ⬇️

scientific article published on 09 March 2011

Aggressive tumor microenvironment of solid predominant lung adenocarcinoma subtype harboring with epidermal growth factor receptor mutations

scientific article published on 15 November 2015

Aldehyde dehydrogenase 1 expression in cancer cells could have prognostic value for patients with non-small cell lung cancer who are treated with neoadjuvant therapy: identification of prognostic microenvironmental factors after chemoradiation

scientific article published in December 2013

Amelioration of type II diabetes in db/db mice by continuous low-dose-rate gamma irradiation

scientific article published on 01 May 2007

Area of residual tumor (ART) can predict prognosis after post neoadjuvant therapy resection for pancreatic ductal adenocarcinoma

scientific article published on 20 November 2019

Area of residual tumor beyond the muscular layer is a useful predictor of outcome in rectal cancer patients who receive preoperative chemoradiotherapy

scientific article published on 01 December 2009

Artificial intelligence system for detecting superficial laryngopharyngeal cancer with high efficiency of deep learning

scientific article published on 16 June 2020

Assessment of PD-L1 expression and oncogenic gene status in patients with small-cell lung cancer: Immuno-oncology biomarker study in LC-SCRUM-Japan

Association between the mutational smoking signature and the immune microenvironment in lung adenocarcinoma

scientific article published on 01 July 2020

Autophagy is activated in pancreatic cancer cells and correlates with poor patient outcome

scientific article published on 04 July 2008

Blockade of EGFR improves responsiveness to PD-1 blockade in EGFR-mutated non-small cell lung cancer

scientific article published on 01 January 2020

Blockade of paracrine supply of insulin-like growth factors using neutralizing antibodies suppresses the liver metastasis of human colorectal cancers

scientific article

Bone-marrow-derived myofibroblasts contribute to the cancer-induced stromal reaction

scientific article published on 01 September 2003

Breast cancer resistance protein impacts clinical outcome in platinum-based chemotherapy for advanced non-small cell lung cancer

scientific article published in March 2004

CD133 expression in rectal cancer after preoperative chemoradiotherapy

scientific article published on 19 December 2009

CD200-positive cancer associated fibroblasts augment the sensitivity of Epidermal Growth Factor Receptor mutation-positive lung adenocarcinomas to EGFR Tyrosine kinase inhibitors

scientific article

CD44 expression during tumor progression of follicular lymphoma

scientific article

CD44 signaling through focal adhesion kinase and its anti-apoptotic effect

scientific article published on September 2002

Cancer cell invasion driven by extracellular matrix remodeling is dependent on the properties of cancer-associated fibroblasts

scientific article published on 15 September 2015

Cancer cell niche factors secreted from cancer-associated fibroblast by loss of H3K27me3

scientific article published on 13 May 2019

Cancer‐initiating cell marker‐positive cells generate metastatic tumors that recapitulate the histology of the primary tumors ⬇️

scientific article published on February 22, 2013

Carbonic anhydrase IX expression is associated with tumor progression and a poor prognosis of lung adenocarcinoma

scientific article

Carcinosarcoma (pure endocrine cell carcinoma with sarcoma components) of the stomach

scientific article published on 01 August 2003

Centrally located adenocarcinoma with endobronchial polypoid growth: clinicopathological analysis of five cases

scientific article published on 13 December 2010

Changes in the tumor microenvironment during lymphatic metastasis of lung squamous cell carcinoma

scientific article published on 20 October 2016

Characteristic immunophenotype of solid subtype component in lung adenocarcinoma

scientific article published on 06 June 2012

Characterization of the immunophenotype of the tumor budding and its prognostic implications in squamous cell carcinoma of the lung ⬇️

scientific article published on December 6, 2011

Characterization of the tumor immune-microenvironment of lung adenocarcinoma associated with usual interstitial pneumonia

scientific article published on 06 November 2018

Chemopreventive effect of peroxisome proliferator-activated receptor gamma on gastric carcinogenesis in mice

scientific article published in June 2005

Circulating CD14+CD204+ cells predict postoperative recurrence in non-small-cell lung cancer patients

scientific article published on February 2014

Clinical Utility of Histological and Radiological Evaluations of Tumor Necrosis for Predicting Prognosis in Pancreatic Cancer

scientific article published on 01 May 2020

Clinical and Pathological Staging Validation in the Eighth Edition of the TNM Classification for Lung Cancer: Correlation between Solid Size on Thin-Section Computed Tomography and Invasive Size in Pathological Findings in the New T Classification

scientific article published on 13 June 2017

Clinical and molecular factors for selection of nivolumab or irinotecan as third-line treatment for advanced gastric cancer

scientific article published on 17 July 2020

Clinical features of unresectable high-grade lung neuroendocrine carcinoma diagnosed using biopsy specimens

scientific article published on 13 September 2011

Clinical prediction of solitary pulmonary nodule after a curative resection for gastric cancer

scientific article published on 01 December 2018

Clinicopathological characteristics associated with necrosis in pulmonary metastases from colorectal cancer

scientific article published on 14 February 2019

Clinicopathological characteristics of EGFR mutated adenosquamous carcinoma of the lung.

scientific article

Clinicopathological characteristics of primary lung adenocarcinoma predominantly composed of goblet cells in surgically resected cases

scientific article published on 31 May 2011

Clinicopathological significance of cancer stem-like cell markers in high-grade neuroendocrine carcinoma of the lung

scientific article published on 12 May 2015

Clinicopathological significance of caveolin-1 expression by cancer-associated fibroblasts in lung adenocarcinoma

scientific article published on 22 October 2016

Clonal heterogeneity in osteogenic potential of lung cancer-associated fibroblasts: promotional effect of osteogenic progenitor cells on cancer cell migration

scientific article published on 27 April 2016

Collagen type I induces EGFR-TKI resistance in EGFR-mutated cancer cells via mTOR activation through Akt-independent pathway.

scientific article published on 27 April 2018

Combination Chemotherapy with Irinotecan and Cisplatin for Large-Cell Neuroendocrine Carcinoma of the Lung: A Multicenter Phase II Study ⬇️

scientific article published on July 1, 2013

Comedonecrosis is an unfavorable marker in node-negative invasive breast carcinoma

scientific article published on 01 August 2003

Comparison of the expression levels of molecular markers among the peripheral area and central area of primary tumor and metastatic lymph node tumor in patients with squamous cell carcinoma of the lung

scientific article published on 09 January 2015

Complications and outcomes in diffuse large B-cell lymphoma with gastric lesions treated with R-CHOP

scientific article published on 07 February 2019

Correlation between maximum standardized uptake values on FDG-PET and microenvironmental factors in patients with clinical stage IA radiologic pure-solid lung adenocarcinoma

scientific article published on 09 August 2019

Crosstalk Between Cancer Associated Fibroblasts and Cancer Cells in the Tumor Microenvironment After Radiotherapy

scientific article published on 05 March 2017

D2-40-positive solitary fibrous tumors of the pleura: diagnostic pitfall of biopsy specimen

scientific article published on 01 September 2007

Degradation of soluble VEGF receptor-1 by MMP-7 allows VEGF access to endothelial cells

scientific article published on 30 October 2008

Dexamethasone Increases Cisplatin-Loaded Nanocarrier Delivery and Efficacy in Metastatic Breast Cancer by Normalizing the Tumor Microenvironment

scientific article published on 12 June 2019

Differences between squamous cell carcinoma and adenocarcinoma of the lung: are adenocarcinoma and squamous cell carcinoma prognostically equal?

scientific article published on 30 December 2011

Differences in clinicopathological and biological features between central-type and peripheral-type squamous cell carcinoma of the lung

scientific article published on 23 February 2006

Differences of tumor microenvironment between stage I lepidic-positive and lepidic-negative lung adenocarcinomas

scientific article published on 04 June 2018

Distinct clinicopathologic characteristics of lung mucinous adenocarcinoma with KRAS mutation

scientific article

Distinctive histopathological features of lepidic growth predominant node-negative adenocarcinomas 3-5 cm in size.

scientific article published on 21 November 2012

Dominant papillary subtype is a significant predictor of the response to gefitinib in adenocarcinoma of the lung

scientific article published in November 2004

Drastic morphological and molecular differences between lymph node micrometastatic tumors and macrometastatic tumors of lung adenocarcinoma

scientific article published on 18 June 2015

Dynamic molecular changes associated with epithelial-mesenchymal transition and subsequent mesenchymal-epithelial transition in the early phase of metastatic tumor formation

scientific article published on 07 June 2010

Effect of differences in cancer cells and tumor growth sites on recruiting bone marrow-derived endothelial cells and myofibroblasts in cancer-induced stroma.

scientific article published on July 2005

Eg5 expression is closely correlated with the response of advanced non-small cell lung cancer to antimitotic agents combined with platinum chemotherapy

scientific article

Emergence and Targeting of Acquired and Hereditary Resistance to Multikinase RET Inhibition in Patients With RET-Altered Cancer

scientific article published on 11 September 2019

Endoscopic submucosal resection using a ligation device without injection for duodenal neuroendocrine tumors

scientific article published on 02 January 2019

Evaluation of extratumoral lymphatic permeation in non-small cell lung cancer as a means of predicting outcome

scientific article published on 28 November 2006

Excision Repair Cross-Complementing-1 for Small Cell Lung Cancer ⬇️

scientific article published on 01 March 2011

Expression and localization of mRNAs for matrix metalloproteinases and their inhibitors in mixed bronchioloalveolar carcinomas with invasive components.

scientific article published in June 2005

Expression of breast cancer resistance protein is associated with a poor clinical outcome in patients with small-cell lung cancer

scientific article published on 25 November 2008

Expression of podoplanin, CD44, and p63 in squamous cell carcinoma of the lung

scientific article published on 21 July 2009

Expression profiling of receptor tyrosine kinases in high-grade neuroendocrine carcinoma of the lung: a comparative analysis with adenocarcinoma and squamous cell carcinoma

scientific article

Extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue (MALT lymphoma) in the thymus: report of four cases

scientific article published on 23 June 2005

Extraskeletal osteosarcoma arising in anterior mediastinum: brief report with a review of the literature.

scientific article published on July 2009

Extratumoral vascular invasion is a significant prognostic indicator and a predicting factor of distant metastasis in non-small cell lung cancer

scientific article published in July 2010

Ezrin-expressing lung adenocarcinoma cells and podoplanin-positive fibroblasts form a malignant microenvironment

scientific article published on 11 October 2014

Factors influencing the concordance of histological subtype diagnosis from biopsy and resected specimens of lung adenocarcinoma

scientific article

Fatal infectious mononucleosis with evidence suggestive of the development of B cell lymphoma ⬇️

scientific article published on September 1, 2003

Fibroblast-led cancer cell invasion is activated by epithelial-mesenchymal transition through platelet-derived growth factor BB secretion of lung adenocarcinoma

scientific article

Fibroblasts associated with cancer cells keep enhanced migration activity after separation from cancer cells: a novel character of tumor educated fibroblasts

scientific article published on August 2010

Fibroblasts-dependent invasion of podoplanin-positive cancer stem cells in squamous cell carcinoma

scientific article published on 09 February 2020

Fibrous stroma is associated with poorer prognosis in lung squamous cell carcinoma patients

scientific article published in September 2011

Forkhead box P3 regulatory T cells coexisting with cancer associated fibroblasts are correlated with a poor outcome in lung adenocarcinoma

scientific article published on 19 February 2013

Frequent overexpression of the c-kit protein in large cell neuroendocrine carcinoma of the lung ⬇️

scientific article published on May 1, 2003

Gastrointestinal Fibroblasts Have Specialized, Diverse Transcriptional Phenotypes: A Comprehensive Gene Expression Analysis of Human Fibroblasts

scientific article published on 5 June 2015

Genetic profiling-based prognostic prediction of patients with advanced small-cell lung cancer in large scale analysis

scientific article published on 12 November 2018

Genomic Profiling of Large-Cell Neuroendocrine Carcinoma of the Lung

scientific article published on 9 August 2016

Ground-Glass Opacity Is a Strong Prognosticator for Pathologic Stage IA Lung Adenocarcinoma

scientific article published on 12 March 2019

Growth inhibition of human prostate cancer cells in human adult bone implanted into nonobese diabetic/severe combined immunodeficient mice by a ligand-specific antibody to human insulin-like growth factors

scientific article published on September 2004

Growth patterns of small peripheral squamous cell carcinoma of the lung and their impacts on pathological and biological characteristics of tumor cells

scientific article published on 21 May 2019

Histological progression of small intrapulmonary metastatic tumor from primary lung adenocarcinoma

scientific article published on 14 September 2010

Histopathologic features of the tumor budding in adenocarcinoma of the lung: tumor budding as an index to predict the potential aggressiveness

scientific article published in September 2010

Histopathologic prognostic factors in resected colorectal lung metastases

scientific article

Hormonal stimulation increases the recruitment of bone marrow-derived myoepithelial cells and periductal fibroblasts into the mammary gland

scientific article published on 13 June 2006

Human subperitoneal fibroblast and cancer cell interaction creates microenvironment that enhances tumor progression and metastasis

scientific article

Human vascular adventitial fibroblasts contain mesenchymal stem/progenitor cells

scientific article published on 28 January 2008

Identification of a low risk subgroup of stage IB lung adenocarcinoma patients

scientific article published on 19 May 2008

Identification of a lung adenocarcinoma cell line with CCDC6-RET fusion gene and the effect of RET inhibitors in vitro and in vivo

scientific article published on 12 May 2013

Identification of biological properties of intralymphatic tumor related to the development of lymph node metastasis in lung adenocarcinoma

scientific article

Identification of early t1b lung adenocarcinoma based on thin-section computed tomography findings

scientific article published in October 2013

Identification of intravascular tumor microenvironment features predicting the recurrence of pathological stage I lung adenocarcinoma

scientific article published on 28 July 2013

Identification of prognostic immunophenotypic features in cancer stromal cells of high-grade neuroendocrine carcinomas of the lung

scientific article published on 7 September 2013

Immuno-oncology biomarker study in a large cohort of LC-SCRUM-Japan: Assessment of PD-L1 expression and tumor mutation burden in non-small cell lung cancer patients treated with immune checkpoint inhibitors

Immuno-oncology biomarker study in a large cohort of LC-SCRUM-Japan: LC-SCRUM-IBIS

scientific article

Immuno-oncology biomarker study in non-small cell lung cancer harboring oncogenic driver alterations: LC-SCRUM-IBIS

scientific article

Immunohistochemical and genetic characteristics of lung cancer mimicking organizing pneumonia

scientific article published on 5 October 2017

Immunohistochemical detection of CD133 expression in colorectal cancer: a clinicopathological study

scientific article

Immunohistochemical differential diagnosis between large cell neuroendocrine carcinoma and small cell carcinoma by tissue microarray analysis with a large antibody panel

scientific article

Immunohistochemical differential diagnosis between thymic carcinoma and type B3 thymoma: diagnostic utility of hypoxic marker, GLUT-1, in thymic epithelial neoplasms

scientific article published on 31 July 2009

Immunohistochemical expression of BCRP and ERCC1 in biopsy specimen predicts survival in advanced non-small-cell lung cancer treated with cisplatin-based chemotherapy

scientific article published on 26 September 2008

Immunophenotypic features of metastatic lymph node tumors to predict recurrence in N2 lung squamous cell carcinoma.

scientific article

Immunosuppressive tumor microenvironment of usual interstitial pneumonia-associated squamous cell carcinoma of the lung

scientific article published on 12 February 2018

Impact of SWI/SNF complex mutations in patients with non-small cell lung cancer (NSCLC) treated with immune checkpoint inhibitors: Immuno-oncology biomarker study in LC-SCRUM-Japan (LC-SCRUM-IBIS)

scientific article

Impact of extratumoral lymphatic permeation on postoperative survival of non-small-cell lung cancer patients

scientific article

Impressive response to nivolumab of non-small-cell lung cancer containing sarcomatoid components

scientific article published on 20 August 2019

Improvement of the breaking strength of wound by combined treatment with recombinant human G-CSF, recombinant human M-CSF, and a TGF-beta1 receptor kinase inhibitor in rat skin

scientific article published in May 2008

In vivo and in vitro characterization of human fibroblasts recruited selectively into human cancer stroma.

scientific article

In vivo characterization of bone marrow-derived fibroblasts recruited into fibrotic lesions.

scientific article published in May 2005

Influence of Ground-Glass Opacity and the Corresponding Pathological Findings on Survival in Patients with Clinical Stage I Non-Small Cell Lung Cancer

scientific article published on 12 December 2017

Influence of cigarette smoking on histological subtypes of stage I lung adenocarcinoma

scientific article published on 01 April 2011

Influence of cigarette smoking on survival and tumor invasiveness in clinical stage IA lung adenocarcinoma

scientific article published on 14 March 2012

Inhibition of bone-derived insulin-like growth factors by a ligand-specific antibody suppresses the growth of human multiple myeloma in the human adult bone explanted in NOD/SCID mouse

scientific article published on May 2006

Interaction between cancer cells and cancer-associated fibroblasts after cisplatin treatment promotes cancer cell regrowth

scientific article published on 22 August 2019

Interleukin-11 as a stimulatory factor for bone formation prevents bone loss with advancing age in mice

scientific article published on 15 October 2002

Interstitial growth as an aggressive growth pattern in primary lung cancer

scientific article

Intrapulmonary metastasis in resected pathologic stage IIIB non-small cell lung cancer: possible contribution of aerogenous metastasis to the favorable outcome

scientific article published in August 2007

Intratumor microvessel density in biopsy specimens predicts local response of hypopharyngeal cancer to radiotherapy

scientific article published on 01 December 2003

Large pulmonary sclerosing pneumocytoma with massive necrosis and vascular invasion: a case report

scientific article published on 01 July 2019

Late pulmonary metastasis of a rectal cancer resected 20 years after low anterior resection

scientific article published on 01 December 2008

Late pulmonary metastasis of renal cell carcinoma resected 25 years after nephrectomy.

scientific article published on January 2004

Limited resection trial for pulmonary ground-glass opacity nodules: case selection based on high-resolution computed tomography-interim results

scientific article published on 21 April 2015

Link between tumor-promoting fibrous microenvironment and an immunosuppressive microenvironment in stage I lung adenocarcinoma

scientific article published on 28 October 2018

Long-term outcome and late recurrence in patients with completely resected stage IA non-small cell lung cancer

scientific article published on 01 August 2010

Long-term outcomes of 50 cases of limited-resection trial for pulmonary ground-glass opacity nodules

scientific article published in October 2012

Long-term survival and risk factors for recurrence in stage I non-small cell lung cancer patients with tumors up to 3 cm in maximum dimension

scientific article published on 30 April 2010

Long-term survival in two cases of resected gastric metastasis of pulmonary pleomorphic carcinoma

scientific article published on 01 July 2008

Low levels of insulin-like growth factor type 1 receptor expression at cancer cell membrane predict liver metastasis in Dukes' C human colorectal cancers

scientific article published on 01 December 2004

Low podoplanin expression of tumor cells predicts poor prognosis in pathological stage IB squamous cell carcinoma of the lung, tissue microarray analysis of 136 patients using 24 antibodies

scientific article published on 25 July 2008

Low-dose CT lung cancer screening in never-smokers and smokers: results of an eight-year observational study

scientific article published on 01 February 2020

Machine learning-based histological classification that predicts recurrence of peripheral lung squamous cell carcinoma

scientific article published on 18 July 2020

Malignant granular cell tumor of the posterior mediastinum with dissemination

scientific article published in February 2012

Malignant pleural mesothelioma with osteosarcomatous differentiation: characteristic bone scintigraphy findings associated with enhanced tumorous osteogenesis☆ ⬇️

scientific article published on December 4, 2010

Matrix metalloproteinase-7 degrades all insulin-like growth factor binding proteins and facilitates insulin-like growth factor bioavailability

scientific article published on August 2005

Matrix metalloproteinase-7 facilitates insulin-like growth factor bioavailability through its proteinase activity on insulin-like growth factor binding protein 3.

scientific article published on January 2004

Matrix metalloproteinase-7 triggers the matricrine action of insulin-like growth factor-II via proteinase activity on insulin-like growth factor binding protein 2 in the extracellular matrix.

scientific article published on 14 March 2007

Mediastinal nodal involvement in patients with clinical stage I non-small-cell lung cancer: possibility of rational lymph node dissection

scientific article published on 01 June 2015

Metabolic Determinants of Sensitivity to Phosphatidylinositol 3-Kinase Pathway Inhibitor in Small-Cell Lung Carcinoma.

scientific article published on 28 February 2018

Microenvironmental changes in the progression from adenocarcinoma in situ to minimally invasive adenocarcinoma and invasive lepidic predominant adenocarcinoma of the lung

scientific article published on 27 July 2016

Morphological, immune and genetic features in biopsy sample associated with the efficacy of pembrolizumab in patients with non-squamous non-small cell lung cancer

scientific article published on 30 September 2020

Morphophenotype of floating colonies derived from a single cancer cell has a critical impact on tumor-forming activity

scientific article published on 7 January 2013

Morphophenotypic characteristics of intralymphatic cancer and stromal cells susceptible to lymphogenic metastasis

scientific article published on 23 April 2012

Multiple Perivascular Epithelioid Cell Tumors: Clear Cell Tumor of the Lung Accompanied by Angiomyolipoma of the Liver ⬇️

scientific article published on April 20, 2013

Multiple sclerosing hemangiomas with a 10-year history

scientific article published in January 2005

Mutational status of EGFR and KIT in thymoma and thymic carcinoma

scientific article published on 29 April 2008

Nationwide genomic screening network for the development of novel targeted therapies in advanced non-small cell lung cancer (LC-SCRUM-Japan)

Nationwide genomic screening network for the development of targeted therapies in NSCLC (LC-SCRUM-Japan)

scientific article

Nerve invasion distance is dependent on laminin gamma2 in tumors of pancreatic cancer

scientific article

Non-small cell lung cancer with loss of expression of the SWI/SNF complex is associated with aggressive clinicopathological features, PD-L1-positive status, and high tumor mutation burden

scientific article published on 13 October 2019

Nuclear beta-catenin accumulation as a prognostic factor in Dukes' D human colorectal cancers

scientific article published on August 2004

Number of circulating endothelial progenitor cells and intratumoral microvessel density in non-small cell lung cancer patients: differences in angiogenic status between adenocarcinoma histologic subtypes

scientific article published on 01 March 2012

Optimal method for measuring invasive size that predicts survival in invasive mucinous adenocarcinoma of the lung

scientific article published on 22 February 2020

Organoid culture containing cancer cells and stromal cells reveals that podoplanin-positive cancer-associated fibroblasts enhance proliferation of lung cancer cells

scientific article published on 08 April 2019

P31: Salvage surgery for PMGCT: beneficial for persistent positive-marker patients?

scientific article published in December 2015

PTPRZ1 regulates calmodulin phosphorylation and tumor progression in small-cell lung carcinoma ⬇️

scientific article published on November 21, 2012

Perioperative pirfenidone treatment as prophylaxis against acute exacerbation of idiopathic pulmonary fibrosis: a single-center analysis

scientific article published on 06 March 2020

Peritoneal elastic laminal invasion of colorectal cancer: the diagnostic utility and clinicopathologic relationship

scientific article published on 01 September 2010

Phenotypic and functional heterogeneity of cancer-associated fibroblast within the tumor microenvironment

scientific article published on 13 August 2015

Pitfalls in lymph node staging with positron emission tomography in non-small cell lung cancer patients

scientific article published in February 2005

Pleomorphic carcinoma of the lung expressing podoplanin and calretinin

scientific article published in December 2008

Pleomorphic carcinoma of the lung: clinicopathologic characteristics of 70 cases

scientific article published on 01 November 2008

Podoplanin - an emerging cancer biomarker and therapeutic target.

scientific article published on 25 March 2018

Podoplanin expression by cancer associated fibroblasts predicts poor prognosis of lung adenocarcinoma

scientific article published on 01 September 2008

Podoplanin promotes progression of malignant pleural mesothelioma by regulating motility and focus formation

scientific article

Podoplanin, a novel marker of tumor-initiating cells in human squamous cell carcinoma A431.

scientific article

Podoplanin-Positive Fibroblasts Enhance Lung Adenocarcinoma Tumor Formation: Podoplanin in Fibroblast Functions for Tumor Progression ⬇️

scientific article published on May 24, 2011

Podoplanin-expressing cancer-associated fibroblasts inhibit small cell lung cancer growth

scientific article published in April 2015

Podoplanin-expressing cancer-associated fibroblasts lead and enhance the local invasion of cancer cells in lung adenocarcinoma

scientific article published on 20 February 2015

Podoplanin-positive cancer-associated fibroblast recruitment within cancer stroma is associated with a higher number of single nucleotide variants in cancer cells in lung adenocarcinoma

scientific article published on 6 March 2018

Podoplanin-positive cancer-associated fibroblasts could have prognostic value independent of cancer cell phenotype in stage I lung squamous cell carcinoma: usefulness of combining analysis of both cancer cell phenotype and cancer-associated fibrobla

scientific article published in April 2013

Podoplanin-positive cancer-associated fibroblasts in the tumor microenvironment induce primary resistance to EGFR-TKIs in lung adenocarcinoma with EGFR mutation

scientific article

Poor prognostic factors in patients with stage IB non-small cell lung cancer according to the seventh edition TNM classification

scientific article published on 19 August 2010

Possible delayed cut-end recurrence after limited resection for ground-glass opacity adenocarcinoma, intraoperatively diagnosed as Noguchi type B, in three patients

scientific article published in April 2010

Predictive factors for local recurrence of resected colorectal lung metastases

scientific article published in September 2005

Predictive factors of pathologically proven noninvasive tumor characteristics in T1aN0M0 peripheral non-small cell lung cancer.

scientific article published on 18 August 2011

Predictive markers for late cervical metastasis in stage I and II invasive squamous cell carcinoma of the oral tongue

scientific article published on 01 January 2004

Predominant infiltration of macrophages and CD8(+) T Cells in cancer nests is a significant predictor of survival in stage IV nonsmall cell lung cancer

scientific article

Presence of human circulating progenitor cells for cancer stromal fibroblasts in the blood of lung cancer patients

scientific article published on 22 March 2007

Presence of podoplanin-positive cancer-associated fibroblasts in surgically resected primary lung adenocarcinoma predicts a shorter progression-free survival period in patients with recurrences who received platinum-based chemotherapy

scientific article published on 02 December 2014

Primary lung adenocarcinoma with massive lymphocyte infiltration

scientific article published on 01 April 2005

Primary lung carcinoma with signet-ring cell carcinoma components: clinicopathological analysis of 39 cases

scientific article published on 01 July 2004

Prognostic Impact of Cancer-Associated Stromal Cells in Patients With Stage I Lung Adenocarcinoma ⬇️

scientific article published on July 1, 2012

Prognostic Impact of the Number of Metastatic Lymph Nodes on the Eighth Edition of the TNM Classification of NSCLC

scientific article published on 02 May 2019

Prognostic impact of CD204-positive macrophages in lung squamous cell carcinoma: possible contribution of Cd204-positive macrophages to the tumor-promoting microenvironment.

scientific article

Prognostic impact of histology on early-stage non-small cell lung cancer

scientific article published on 16 December 2010

Prognostic impact of intratumoral vascular invasion in non-small cell lung cancer patients.

scientific article published on 22 October 2010

Prognostic impact of intratumoural microvascular invasion and microlymphatic permeation on node-negative non-small-cell lung cancer: which indicator is the stronger prognostic factor?

scientific article published on 3 August 2012

Prognostic impact of microscopic vessel invasion and visceral pleural invasion in non-small cell lung cancer: a retrospective analysis of 2657 patients

scientific article published in August 2014

Prognostic impact of node involvement pattern in pN1 non-small cell lung cancer patients

scientific article published in October 2010

Prognostic impact of node involvement pattern in pulmonary pN1 squamous cell carcinoma patients

scientific article

Prognostic significance of a solid component in pulmonary adenocarcinoma.

scientific article

Prognostic significance of carbonic anhydrase IX expression by cancer-associated fibroblasts in lung adenocarcinoma

scientific article published in June 2009

Proportion of goblet cell is associated with malignant potential in invasive mucinous adenocarcinoma of the lung

scientific article published on 01 September 2019

Prostate-specific antigen enhances bioavailability of insulin-like growth factor by degrading insulin-like growth factor binding protein 5.

scientific article published on 23 January 2009

Prostate-specific antigen induces apoptosis of osteoclast precursors: potential role in osteoblastic bone metastases of prostate cancer

scientific article published on November 2006

Pulmonary metastasis from encapsulated cervical ectopic type a thymoma

scientific article published in December 2012

Radiologic Criteria in Predicting Pathologic Less Invasive Lung Cancer According to TNM 8th Edition

scientific article published on 15 November 2018

Randomized Phase III Study of Irinotecan Plus Cisplatin Versus Etoposide Plus Cisplatin for Completely Resected High-Grade Neuroendocrine Carcinoma of the Lung: JCOG1205/1206

scientific article published on 02 November 2020

Reasonable extent of lymph node dissection in intentional segmentectomy for small-sized peripheral non-small-cell lung cancer: from the clinicopathological findings of patients who underwent lobectomy with systematic lymph node dissection

scientific article published on 01 November 2012

Recruitment of podoplanin positive cancer-associated fibroblasts in metastatic lymph nodes predicts poor prognosis in pathological N2 stage III lung adenocarcinoma

scientific article published on 6 June 2012

Reply to Wang et al.

scientific article published on 11 December 2012

Review of cancer-associated fibroblasts and their microenvironment in post-chemotherapy recurrence

scientific article published on 27 August 2020

Risk factors for tumor recurrence in patients with early-stage (stage I and II) non-small cell lung cancer: patient selection criteria for adjuvant chemotherapy according to the seventh edition TNM classification

scientific article published on 26 May 2011

Roles of osteoclasts and bone-derived IGFs in the survival and growth of human breast cancer cells in human adult bone implanted into nonobese diabetic/severe combined immunodeficient mice

scientific article

Secretion of high amounts of hepatocyte growth factor is a characteristic feature of cancer-associated fibroblasts with EGFR-TKI resistance-promoting phenotype: A study of 18 cases of cancer-associated fibroblasts

scientific article published on 24 July 2019

Sensitivity of breast cancer cell lines to the novel insulin-like growth factor-1 receptor (IGF-1R) inhibitor NVP-AEW541 is dependent on the level of IRS-1 expression

scientific article published on 3 April 2009

Signaling through the Phosphatidylinositol 3-Kinase (PI3K)/Mammalian Target of Rapamycin (mTOR) Axis Is Responsible for Aerobic Glycolysis mediated by Glucose Transporter in Epidermal Growth Factor Receptor (EGFR)-mutated Lung Adenocarcinoma

scientific article published on 28 May 2015

Significance of cancer-associated fibroblasts in the regulation of gene expression in the leading cells of invasive lung cancer.

scientific article published on 30 October 2012

Simultaneous squamous cell carcinoma with leiomyosarcoma of the larynx

scientific article published on 09 July 2008

Single cell time-lapse analysis reveals that podoplanin enhances cell survival and colony formation capacity of squamous cell carcinoma cells

scientific article published on 06 January 2017

Solid predominant histology predicts EGFR tyrosine kinase inhibitor response in patients with EGFR mutation-positive lung adenocarcinoma

scientific article published on 22 August 2013

Spatiotemporal characteristics of fibroblasts-dependent cancer cell invasion

scientific article published on 23 November 2018

Stapling cartridge lavage cytology in limited resection for pulmonary malignant tumors: assessment of cytological status of the surgical margin

Stromal MCP-1 in mammary tumors induces tumor-associated macrophage infiltration and contributes to tumor progression

scientific article published in September 2009

Stromal macrophage expressing CD204 is associated with tumor aggressiveness in lung adenocarcinoma

scientific article published in October 2010

Structural and biological properties of a papillary component generating a micropapillary component in lung adenocarcinoma

scientific article published on 29 May 2009

Subcarinal lymph node in upper lobe non-small cell lung cancer patients: is selective lymph node dissection valid?

scientific article published on 16 March 2010

Successful treatment with nivolumab for SMARCA4-deficient non-small cell lung carcinoma with a high tumor mutation burden: A case report

scientific article published on 10 April 2019

Surgical outcomes after initial surgery for clinical single-station N2 non-small-cell lung cancer

scientific article published on 7 November 2013

Surgical resection for oral tongue cancer pulmonary metastases

scientific article published on 31 March 2010

Survival and prognostic factors after pulmonary metastasectomy of head and neck cancer: what are the clinically informative prognostic indicators?

scientific article published on 01 May 2019

The CLIP1-LTK fusion is an oncogenic driver in non-small-cell lung cancer

scientific article published on 24 November 2021

The Differences of Biological Behavior Based on the Clinicopathological Data Between Resectable Large-Cell Neuroendocrine Carcinoma and Small-Cell Lung Carcinoma ⬇️

scientific article published on June 20, 2013

The Lung Cancer Genomic Screening Project for Individualized Medicine in Japan (LC-SCRUM-Japan): Screening for RET and ROS1 fusions in advanced EGFR mutation-negative nonsquamous lung cancer and development of molecular targeted therapy

The PD-1 expression balance between effector and regulatory T cells predicts the clinical efficacy of PD-1 blockade therapies

scientific article published on 31 August 2020

The association of intravascular stromal cells with prognosis in high-grade neuroendocrine carcinoma of the lung

scientific article published on 22 December 2015

The availability of pre- and intraoperative evaluation of a solitary pulmonary nodule in breast cancer patients

scientific article published on 16 May 2014

The clinical outcome of non-small cell lung cancer patients with adjacent lobe invasion: the optimal classification according to the status of the interlobar pleura at the invasion point.

scientific article published on 16 May 2012

The difference in Ezrin-pAkt signaling axis between lepidic and papillary predominant invasive adenocarcinomas of the lung

scientific article published on 08 April 2016

The efficacy of immune checkpoint inhibitors and PD-L1 status in patients with advanced non-small cell lung cancer harboring oncogenic driver alterations: Immuno-oncology biomarker study in LC-SCRUM-Japan

The impact of molecular subtype on efficacy of chemotherapy and checkpoint inhibition in advanced gastric cancer

scientific article published on 10 March 2020

The impact on survival of positive intraoperative pleural lavage cytology in patients with non-small-cell lung cancer

scientific article published on 17 September 2009

The lymphatic infiltration identified by D2-40 monoclonal antibody predicts lymph node metastasis in submucosal invasive colorectal cancer.

scientific article published on 13 December 2007

The novel one-step nucleic acid amplification (OSNA) assay for the diagnosis of lymph node metastasis in patients with non-small cell lung cancer (NSCLC): Results of a multicenter prospective study

scientific article published on 28 March 2016

The prognostic impact of cigarette smoking on patients with non-small cell lung cancer

scientific article published on 01 April 2011

The ratio of cancer cells to stroma after induction therapy in the treatment of non-small cell lung cancer

scientific article published on 17 September 2016

The ratio of cancer cells to stroma within the invasive area is a histologic prognostic parameter of lung adenocarcinoma

scientific article published on 31 January 2018

The recurrence of malignant pleural mesothelioma 14 years after extrapleural pneumonectomy: possible histological transformation

scientific article published in November 2012

Therapeutic priority of the PI3K/AKT/mTOR pathway in small cell lung cancers as revealed by a comprehensive genomic analysis

scientific article

Thin-section computed tomography findings of lung adenocarcinoma with inherent metastatic potential

scientific article published on 22 September 2016

Topographical distribution of allelic loss in individual lung adenocarcinomas with lymph node metastases

scientific article published on 01 February 2004

Tumor invasion of extralobar soft tissue beyond the hilar region does not affect the prognosis of surgically resected lung cancer patients

scientific article published in October 2010

Tumor promoting effect of podoplanin-positive fibroblasts is mediated by enhanced RhoA activity

scientific article published on 7 May 2012

Tumor-Infiltrating T Cells Concurrently Overexpress CD200R with Immune Checkpoints PD-1, CTLA-4, and TIM-3 in Non-Small-Cell Lung Cancer

scientific article published on 15 December 2020

Tumor-size-based morphological features of metastatic lymph node tumors from primary lung adenocarcinoma

scientific article published on 30 October 2014

Two lung adenocarcinomas in the same lobe: multiple primaries or intrapulmonary metastasis?

scientific article

Unique intravascular tumor microenvironment predicting recurrence of lung squamous cell carcinoma

scientific article published on 31 October 2015

Uptake of collagen type I via macropinocytosis cause mTOR activation and anti-cancer drug resistance

scientific article published on 19 March 2020

Utility of Site-Specific Biopsy for Diagnosis of Desmoplastic Malignant Mesothelioma.

scientific article published on 27 March 2018

Validity of using immunohistochemistry to predict treatment outcome in patients with non-small cell lung cancer not otherwise specified

scientific article published on 07 September 2019

Vandetanib in patients with previously treated RET-rearranged advanced non-small-cell lung cancer (LURET): an open-label, multicentre phase 2 trial

scientific article published on 4 November 2016

Vascular invasion is a strong prognostic factor after complete resection of node-negative non-small cell lung cancer.

scientific article published in July 2010

Visceral pleural invasion classification in non-small cell lung cancer.

scientific article

Visceral pleural invasion classification in non-small cell lung cancer: a proposal on the basis of outcome assessment

scientific article published on 01 June 2004

Visceral pleural invasion is an invasive and aggressive indicator of non-small cell lung cancer

scientific article published in July 2005

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