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List of works by Thomas Jaki

A Bayesian adaptive design for clinical trials in rare diseases

scientific article published on 28 September 2016

A critical review of graphics for subgroup analyses in clinical trials

scientific article published on 25 March 2020

A dose-finding design for dual-agent trials with patient-specific doses for one agent with application to an opiate detoxification trial

scientific article published on 10 December 2021

A false sense of security? Can tiered approach be trusted to accurately classify immunogenicity samples?

scientific article published on 27 May 2016

A formal comparison of different methods for establishing cut points to distinguish positive and negative samples in immunoassays ⬇️

scientific article published on April 15, 2011

A framework for prospectively defining progression rules for internal pilot studies monitoring recruitment

scientific article published in January 2017

A proposal for a new PhD level curriculum on quantitative methods for drug development.

scientific article

Adaptive clinical trials in tuberculosis: applications, challenges and solutions

scientific article published on June 2015

Analysing malaria drug trials on a per‐individual or per‐clone basis: a comparison of methods ⬇️

scientific article published on December 19, 2012

Assessing goodness-of-fit for evaluation of dose-proportionality

scientific article published on 15 October 2020

Assessing the feasibility of injectable growth-promoting therapy in Crohn's disease

scientific article published on 05 December 2016

Asymmetric inner wedge group sequential tests with applications to verifying whether effective drug concentrations are similar in adults and children.

scientific article published on 8 November 2016

Bayesian adaptive dose-escalation designs for simultaneously estimating the optimal and maximum safe dose based on safety and efficacy.

scientific article

Bayesian adaptive dose-escalation procedures for binary and continuous responses utilizing a gain function

scientific article

Bayesian sequential integration within a preclinical pharmacokinetic and pharmacodynamic modeling framework: Lessons learned

scientific article published on 01 April 2019

Considerations on covariates and endpoints in multi‐arm multi‐stage clinical trials selecting all promising treatments ⬇️

scientific article published on October 30, 2012

Designing and evaluating dose-escalation studies made easy: The MoDEsT web app

scientific article published on 19 December 2019

Designing exploratory cancer trials using change in tumour size as primary endpoint ⬇️

scientific article published on December 19, 2012

Designing multi-arm multi-stage clinical trials using a risk-benefit criterion for treatment selection

scientific article published on 12 October 2015

Endpoints for randomized controlled clinical trials for COVID-19 treatments

scientific article published on 16 July 2020

Generalisations of a Bayesian decision-theoretic randomisation procedure and the impact of delayed responses

scientific article published in 2022

Impact of an equality constraint on the class-specific residual variances in regression mixtures: A Monte Carlo simulation study

scientific article

Model selection based on combined penalties for biomarker identification

scientific article

Randomized dose-escalation designs for drug combination cancer trials with immunotherapy

scientific article published on 23 October 2018

Recruitment progression rules for internal pilot studies monitoring recruitment.

scientific article

Response to comments on Jaki et al., A proposal for a new PhD level curriculum on quantitative methods for drug development. Pharm Stat 17(5):593-606, Sep/Oct 2018., DOI: https://doi.org/10.1002/pst.1873

scientific article published on 14 March 2019

Simultaneous confidence regions for multivariate bioequivalence

scientific article published on 30 August 2017

Statistical evaluation of toxicological assays: Dunnett or Williams test—take both ⬇️

scientific article published on May 8, 2013

Telmisartan to reduce insulin resistance in HIV-positive individuals on combination antiretroviral therapy: the TAILoR dose-ranging Phase II RCT

Understanding clinical prediction models as 'innovations': a mixed methods study in UK family practice

scientific article

Uptake of novel statistical methods for early-phase clinical studies in the UK public sector ⬇️

scientific article published on February 1, 2013

Why are two mistakes not worse than one? A proposal for controlling the expected number of false claims

scientific article published on 20 April 2016

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