List of works - Amelie Lupp

A microfluidically perfused three dimensional human liver model

scientific article published on 25 August 2015

A synopsis on different homologous series of fomocaine derivatives. In vitro interactions with the cytochrome P450 system, toxicity, and local anaesthetic effects in rats--Part 1.

scientific article published in January 2007

A synopsis on different homologous series of fomocaine derivatives. In vitro interactions with the cytochrome P450 system, toxicity, and local anaesthetic effects in rats--Part III.

scientific article published on January 2007

A synopsis on different homologous series of fomocaine derivatives. In vitro interactions with the cytochrome P450 system, toxicity, and local anaesthetic effects in rats--part II.

scientific article published in January 2007

Acid Sphingomyelinase Inhibition Prevents Development of Sepsis Sequelae in the Murine Liver

scientific article published on 27 September 2017

Acid Sphingomyelinase Inhibition Stabilizes Hepatic Ceramide Content and Improves Hepatic Biotransformation Capacity in a Murine Model of Polymicrobial Sepsis

scientific article published on 15 October 2018

Adjustment of Dysregulated Ceramide Metabolism in a Murine Model of Sepsis-Induced Cardiac Dysfunction

scientific article

Administration of AMD3100 in endotoxemia is associated with pro-inflammatory, pro-oxidative, and pro-apoptotic effects in vivo

scientific article

Administration of a CXCL12 Analog in Endotoxemia Is Associated with Anti-Inflammatory, Anti-Oxidative and Cytoprotective Effects In Vivo

scientific article (publication date: 2015)

Analgesic tolerance to high-efficacy agonists but not to morphine is diminished in phosphorylation-deficient S375A μ-opioid receptor knock-in mice.

scientific article published on September 2011

Analysis of somatostatin receptor 2A immunohistochemistry, RT-qPCR, and in vivo PET/CT data in patients with pancreatic neuroendocrine neoplasm.

scientific article

Blue light stress in retinal neuronal (R28) cells is dependent on wavelength range and irradiance ⬇️

scientific article published on July 22, 2011

CXC chemokine receptor 7 (CXCR7) regulates CXCR4 protein expression and capillary tuft development in mouse kidney

scientific article

Case report of a cystic parathyroidal adenoma with rapid growth induced by cinacalcet

scientific article published on 20 April 2020

Ciprofibrate, clofibric acid and respective glycinate derivatives. Effects of a four-week treatment on male lean and obese Zucker rats

scientific article published in January 2008

Comparative evaluation of three proliferation markers, Ki-67, TOP2A, and RacGAP1, in bronchopulmonary neuroendocrine neoplasms: Issues and prospects

scientific article published on 31 May 2016

Comparing of IRS and Her2 as immunohistochemical scoring schemes in gastroenteropancreatic neuroendocrine tumors

scientific article

Comparison of immunoreactive score, HER2/neu score and H score for the immunohistochemical evaluation of somatostatin receptors in bronchopulmonary neuroendocrine neoplasms

scientific article published on February 2015

Comprehensive Assessment of GPR68 Expression in Normal and Neoplastic Human Tissues Using a Novel Rabbit Monoclonal Antibody

scientific article published on 23 October 2019

Comprehensive assessment of tissue and serum parameters of bone metabolism in a series of orthopaedic patients

scientific article published on 27 December 2019

Comprehensive comparison of three different animal models for systemic inflammation

scientific article published on 24 August 2017

Correlation of monoclonal and polyclonal somatostatin receptor 5 antibodies in pancreatic neuroendocrine tumors ⬇️

scientific article published on November 20, 2012

Corrigendum: Monocyte-induced recovery of inflammation-associated hepatocellular dysfunction in a biochip-based human liver model.

scientific article

Cxcr4 distinguishes HSC-derived monocytes from microglia and reveals monocyte immune responses to experimental stroke

scientific article published on 10 February 2020

Cyclosporine A and tacrolimus: in vitro investigations on the differential interactions with the cytochrome P450 system in rat and human liver

scientific article published in June 2003

Design, synthesis and biological evaluation of D-ring opened galantamine analogs as multifunctional anti-Alzheimer agents

scientific article

Developmental changes in glutathione S-transferase isoforms expression and activity in intrasplenic fetal liver tissue transplants in rats ⬇️

scientific article published on September 1, 2003

Different somatostatin and CXCR4 chemokine receptor expression in gastroenteropancreatic neuroendocrine neoplasms depending on their origin

scientific article published on 13 March 2019

Differential antiinflammatory and antinociceptive effects of the somatostatin analogs octreotide and pasireotide in a mouse model of immune-mediated arthritis

scientific article published on 01 August 2011

Differential expression and prognostic value of the chemokine receptor CXCR4 in bronchopulmonary neuroendocrine neoplasms

scientific article published on February 2015

Differential somatostatin and CXCR4 chemokine receptor expression in MALT-type lymphoma of gastric and extragastric origin.

scientific article published on 20 August 2016

Differential somatostatin, CXCR4 chemokine and endothelin A receptor expression in WHO grade I-IV astrocytic brain tumors.

scientific article published on 25 April 2018

Effects of IGM-enriched solution on polymorphonuclear neutrophil function, bacterial clearance, and lung histology in endotoxemia.

scientific article published in February 2008

Effects of Narrow-band IR-A and of Water-Filtered Infrared A on Fibroblasts

scientific article published on 15 February 2016

Effects of a therapy with losartan and quinaprilat on the progression of chronic renal failure in rats after a single dose of uranyl nitrate or 5/6 nephrectomy

scientific article published in June 2003

Effects of different mitogens on intrasplenic liver tissue transplants in comparison to orthotopic liver

scientific article published in June 2003

Effects of vaporized perfluorohexane and partial liquid ventilation on regional distribution of alveolar damage in experimental lung injury

scientific article published on 08 November 2006

Erratum to: Differential somatostatin and CXCR4 chemokine receptor expression in MALT-type lymphoma of gastric and extragastric origin

scientific article published on 01 January 2017

Evaluation of 2-year-old intrasplenic fetal liver tissue transplants in rats.

scientific article

Evaluation of HepaRG cells for the assessment of indirect drug-induced hepatotoxicity using INH as a model substance.

scientific article published on 19 May 2017

Evaluation of Somatostatin and CXCR4 Receptor Expression in a Large Set of Prostate Cancer Samples Using Tissue Microarrays and Well-Characterized Monoclonal Antibodies

scientific article published on 24 May 2020

Evaluation of possible pro- or antioxidative properties and of the interaction capacity with the microsomal cytochrome P450 system of different NMDA-receptor ligands and of taurine in vitro

scientific article published in June 2003

Evaluation of somatostatin, CXCR4 chemokine and endothelin A receptor expression in a large set of paragangliomas

scientific article published on 23 September 2017

Expression and inducibility of cytochrome P450 isoforms in 1-year-old intrasplenic liver cell transplants in rats

scientific article

Fate of extrahepatic human stem and precursor cells after transplantation into mouse livers.

scientific article published in September 2007

Fibrates and their newly synthesized glycinate or glycinate-methylester derivatives: comparison of the interactions with liver cytochrome P450 dependent monooxygenase- and oxidase-functions in vitro

scientific article published in June 2003

Generation of Multicellular Breast Cancer Tumor Spheroids: Comparison of Different Protocols

scientific article published on 12 August 2016

Histomorphological changes and cytochrome P450 isoforms expression and activities in precision-cut liver slices from neonatal rats

scientific article published in January 2005

Immunohistochemical identification of the PTHR1 parathyroid hormone receptor in normal and neoplastic human tissues

scientific article published on 15 February 2010

In vitro interactions with the Cytochrome P450 system, toxicity, and local anaesthetic effects of Fomocaine Alkylmorpholine derivatives in rats

scientific article published in January 2006

Increased oxidative stress in dystrophin deficient (mdx) mice masticatory muscles

scientific article published on 14 May 2010

Influence of recipient gender on cytochrome P450 isoforms expression in intrasplenic fetal liver tissue transplants in rats

scientific article published in June 2003

Influence of recipient gender on intrasplenic fetal liver tissue transplants in rats: cytochrome P450-mediated monooxygenase functions

scientific article published in May 2004

International Union of Basic and Clinical Pharmacology. CV. Somatostatin Receptors: Structure, Function, Ligands, and New Nomenclature

scientific article published on 01 October 2018

Inverse expression of somatostatin and CXCR4 chemokine receptors in gastroenteropancreatic neuroendocrine neoplasms of different malignancy

scientific article

Ischemia reperfusion injury in aged livers - the energy metabolism, inflammatory response and autophagy

scientific article published on 11 November 2017

Liver dysfunction and phosphatidylinositol-3-kinase signalling in early sepsis: experimental studies in rodent models of peritonitis

scientific article (publication date: 2012)

Localization of Radiolabeled Somatostatin Analogs in the Spleen

scientific article published on 12 October 2015

Mechanisms and functional consequences of liver failure substantially differ between endotoxaemia and faecal peritonitis in rats

scientific article

Molecular imaging with ⁶⁸Ga-SSTR PET/CT and correlation to immunohistochemistry of somatostatin receptors in neuroendocrine tumours.

scientific article

Monocyte-induced recovery of inflammation-associated hepatocellular dysfunction in a biochip-based human liver model

scientific article published on 23 February 2016

Morphologically 'invisible' proinsulin - secreting adenoma detected by Ga-68 Exendin-4 (GLP-1 Receptor) positron emission tomography/CT.

scientific article

NO-donating tacrine hybrid compounds improve scopolamine-induced cognition impairment and show less hepatotoxicity

scientific article published in December 2008

Oral Chemical Burns Reported to the Poisons Information Centre in Erfurt, Germany, from 1997 to 2014.

scientific article

Pasireotide and octreotide stimulate distinct patterns of sst2A somatostatin receptor phosphorylation

scientific article

Pharmacological and toxicological testing of the enantiomers of two chiral fomocaine alkylmorpholine derivatives in comparison to their in vitro interactions on drug metabolism in rats

scientific article published in January 2006

Physical exercise induces specific adaptations resulting in reduced organ injury and mortality during severe polymicrobial sepsis

scientific article published in October 2013

Precision-cut liver slices from rats of different ages: basal cytochrome P450-dependent monooxygenase activities and inducibility

scientific article published on 16 July 2008

Primary-like human hepatocytes genetically engineered to obtain proliferation competence display hepatic differentiation characteristics in monolayer and organotypical spheroid cultures

scientific article published on 30 December 2015

Prospective assessment of hepatic function and mechanisms of dysfunction in the critically ill.

scientific article published in October 2009

Proteasome inhibitor bortezomib enhances the effect of standard chemotherapy in small cell lung cancer.

scientific article published on 23 September 2017

Protective Effect of Casperome®, an Orally Bioavailable Frankincense Extract, on Lipopolysaccharide- Induced Systemic Inflammation in Mice.

scientific article

Reassessment of endothelin receptor A expression in normal and neoplastic human tissues using the novel rabbit monoclonal antibody UMB-8

scientific article published on 20 February 2015

Reassessment of sst 5 Somatostatin Receptor Expression in Normal and Neoplastic Human Tissues Using the Novel Rabbit Monoclonal Antibody UMB-4

scientific article published on 27 September 2011

Reassessment of sst3 somatostatin receptor expression in human normal and neoplastic tissues using the novel rabbit monoclonal antibody UMB-5.

scientific article published on 4 May 2012

Reevaluation of sst1 somatostatin receptor expression in human normal and neoplastic tissues using the novel rabbit monoclonal antibody UMB-7

scientific article published on 04 March 2013

SSTR3 is a putative target for the medical treatment of gonadotroph adenomas of the pituitary

scientific article published on 16 December 2014

Single and chronic administration of ciprofibrate or of ciprofibrate-glycinate in male Fischer 344 rats: comparison of the effects on morphological and biochemical parameters in liver and blood.

scientific article

Somatostatin analogs modulate AIP in somatotroph adenomas: the role of the ZAC1 pathway.

scientific article

Somatostatin and CXCR4 chemokine receptor expression in hepatocellular and cholangiocellular carcinomas: tumor capillaries as promising targets

scientific article published on 28 December 2017

Somatostatin and CXCR4 expression patterns in adenocarcinoma and squamous cell carcinoma of the lung relative to small cell lung cancer

scientific article published on 03 August 2018

Somatostatin and chemokine CXCR4 receptor expression in pancreatic adenocarcinoma relative to pancreatic neuroendocrine tumours

scientific article published on 26 August 2019

Somatostatin receptor immunohistochemistry in neuroendocrine tumors: comparison between manual and automated evaluation

scientific article

Somatostatin receptors in bronchopulmonary neuroendocrine neoplasms: new diagnostic, prognostic, and therapeutic markers.

scientific article published on 12 December 2014

Tacrine-NO donor and tacrine-ferulic acid hybrid molecules as new anti-Alzheimer agents: hepatotoxicity and influence on the cytochrome P450 system in comparison to tacrine.

scientific article published in January 2010

Tacrine-Silibinin Codrug Shows Neuro- and Hepatoprotective Effects in Vitro and Pro-Cognitive and Hepatoprotective Effects in Vivo ⬇️

scientific article published on May 24, 2012

Targeting Complement C5a Receptor 1 for the Treatment of Immunosuppression in Sepsis

scientific article published on 05 September 2020

The effect of mild hypothermia on plasma fentanyl concentration and biotransformation in juvenile pigs

scientific article published in April 2005

UMB-3, a novel rabbit monoclonal antibody, for assessing μ-opioid receptor expression in mouse, rat and human formalin-fixed and paraffin-embedded tissues

scientific article published on 17 September 2010

VPAC2 receptor expression in human normal and neoplastic tissues: evaluation of the novel MAB SP235.

scientific article published on 11 December 2014

Vascular CXCR4 expression - a novel antiangiogenic target in gastric cancer?

scientific article

List of works by Amelie Lupp

A microfluidically perfused three dimensional human liver model

A synopsis on different homologous series of fomocaine derivatives. In vitro interactions with the cytochrome P450 system, toxicity, and local anaesthetic effects in rats--Part 1.

A synopsis on different homologous series of fomocaine derivatives. In vitro interactions with the cytochrome P450 system, toxicity, and local anaesthetic effects in rats--Part III.

A synopsis on different homologous series of fomocaine derivatives. In vitro interactions with the cytochrome P450 system, toxicity, and local anaesthetic effects in rats--part II.

Acid Sphingomyelinase Inhibition Prevents Development of Sepsis Sequelae in the Murine Liver

Acid Sphingomyelinase Inhibition Stabilizes Hepatic Ceramide Content and Improves Hepatic Biotransformation Capacity in a Murine Model of Polymicrobial Sepsis

Adjustment of Dysregulated Ceramide Metabolism in a Murine Model of Sepsis-Induced Cardiac Dysfunction

Administration of AMD3100 in endotoxemia is associated with pro-inflammatory, pro-oxidative, and pro-apoptotic effects in vivo

Administration of a CXCL12 Analog in Endotoxemia Is Associated with Anti-Inflammatory, Anti-Oxidative and Cytoprotective Effects In Vivo

Analgesic tolerance to high-efficacy agonists but not to morphine is diminished in phosphorylation-deficient S375A μ-opioid receptor knock-in mice.

Analysis of somatostatin receptor 2A immunohistochemistry, RT-qPCR, and in vivo PET/CT data in patients with pancreatic neuroendocrine neoplasm.

Blue light stress in retinal neuronal (R28) cells is dependent on wavelength range and irradiance ⬇️

CXC chemokine receptor 7 (CXCR7) regulates CXCR4 protein expression and capillary tuft development in mouse kidney

Case report of a cystic parathyroidal adenoma with rapid growth induced by cinacalcet

Ciprofibrate, clofibric acid and respective glycinate derivatives. Effects of a four-week treatment on male lean and obese Zucker rats

Comparative evaluation of three proliferation markers, Ki-67, TOP2A, and RacGAP1, in bronchopulmonary neuroendocrine neoplasms: Issues and prospects

Comparing of IRS and Her2 as immunohistochemical scoring schemes in gastroenteropancreatic neuroendocrine tumors

Comparison of immunoreactive score, HER2/neu score and H score for the immunohistochemical evaluation of somatostatin receptors in bronchopulmonary neuroendocrine neoplasms

Comprehensive Assessment of GPR68 Expression in Normal and Neoplastic Human Tissues Using a Novel Rabbit Monoclonal Antibody

Comprehensive assessment of tissue and serum parameters of bone metabolism in a series of orthopaedic patients

Comprehensive comparison of three different animal models for systemic inflammation

Correlation of monoclonal and polyclonal somatostatin receptor 5 antibodies in pancreatic neuroendocrine tumors ⬇️

Corrigendum: Monocyte-induced recovery of inflammation-associated hepatocellular dysfunction in a biochip-based human liver model.

Cxcr4 distinguishes HSC-derived monocytes from microglia and reveals monocyte immune responses to experimental stroke

Cyclosporine A and tacrolimus: in vitro investigations on the differential interactions with the cytochrome P450 system in rat and human liver

Design, synthesis and biological evaluation of D-ring opened galantamine analogs as multifunctional anti-Alzheimer agents

Developmental changes in glutathione S-transferase isoforms expression and activity in intrasplenic fetal liver tissue transplants in rats ⬇️

Different somatostatin and CXCR4 chemokine receptor expression in gastroenteropancreatic neuroendocrine neoplasms depending on their origin

Differential antiinflammatory and antinociceptive effects of the somatostatin analogs octreotide and pasireotide in a mouse model of immune-mediated arthritis

Differential expression and prognostic value of the chemokine receptor CXCR4 in bronchopulmonary neuroendocrine neoplasms

Differential somatostatin and CXCR4 chemokine receptor expression in MALT-type lymphoma of gastric and extragastric origin.

Differential somatostatin, CXCR4 chemokine and endothelin A receptor expression in WHO grade I-IV astrocytic brain tumors.

Effects of IGM-enriched solution on polymorphonuclear neutrophil function, bacterial clearance, and lung histology in endotoxemia.

Effects of Narrow-band IR-A and of Water-Filtered Infrared A on Fibroblasts

Effects of a therapy with losartan and quinaprilat on the progression of chronic renal failure in rats after a single dose of uranyl nitrate or 5/6 nephrectomy

Effects of different mitogens on intrasplenic liver tissue transplants in comparison to orthotopic liver

Effects of vaporized perfluorohexane and partial liquid ventilation on regional distribution of alveolar damage in experimental lung injury

Erratum to: Differential somatostatin and CXCR4 chemokine receptor expression in MALT-type lymphoma of gastric and extragastric origin

Evaluation of 2-year-old intrasplenic fetal liver tissue transplants in rats.

Evaluation of HepaRG cells for the assessment of indirect drug-induced hepatotoxicity using INH as a model substance.

Evaluation of Somatostatin and CXCR4 Receptor Expression in a Large Set of Prostate Cancer Samples Using Tissue Microarrays and Well-Characterized Monoclonal Antibodies

Evaluation of possible pro- or antioxidative properties and of the interaction capacity with the microsomal cytochrome P450 system of different NMDA-receptor ligands and of taurine in vitro

Evaluation of somatostatin, CXCR4 chemokine and endothelin A receptor expression in a large set of paragangliomas

Expression and inducibility of cytochrome P450 isoforms in 1-year-old intrasplenic liver cell transplants in rats

Fate of extrahepatic human stem and precursor cells after transplantation into mouse livers.

Fibrates and their newly synthesized glycinate or glycinate-methylester derivatives: comparison of the interactions with liver cytochrome P450 dependent monooxygenase- and oxidase-functions in vitro

Generation of Multicellular Breast Cancer Tumor Spheroids: Comparison of Different Protocols

Histomorphological changes and cytochrome P450 isoforms expression and activities in precision-cut liver slices from neonatal rats

Immunohistochemical identification of the PTHR1 parathyroid hormone receptor in normal and neoplastic human tissues

In vitro interactions with the Cytochrome P450 system, toxicity, and local anaesthetic effects of Fomocaine Alkylmorpholine derivatives in rats

Increased oxidative stress in dystrophin deficient (mdx) mice masticatory muscles

Influence of recipient gender on cytochrome P450 isoforms expression in intrasplenic fetal liver tissue transplants in rats

Influence of recipient gender on intrasplenic fetal liver tissue transplants in rats: cytochrome P450-mediated monooxygenase functions

International Union of Basic and Clinical Pharmacology. CV. Somatostatin Receptors: Structure, Function, Ligands, and New Nomenclature

Inverse expression of somatostatin and CXCR4 chemokine receptors in gastroenteropancreatic neuroendocrine neoplasms of different malignancy

Ischemia reperfusion injury in aged livers - the energy metabolism, inflammatory response and autophagy

Liver dysfunction and phosphatidylinositol-3-kinase signalling in early sepsis: experimental studies in rodent models of peritonitis

Localization of Radiolabeled Somatostatin Analogs in the Spleen

Mechanisms and functional consequences of liver failure substantially differ between endotoxaemia and faecal peritonitis in rats

Molecular imaging with ⁶⁸Ga-SSTR PET/CT and correlation to immunohistochemistry of somatostatin receptors in neuroendocrine tumours.

Monocyte-induced recovery of inflammation-associated hepatocellular dysfunction in a biochip-based human liver model

Morphologically 'invisible' proinsulin - secreting adenoma detected by Ga-68 Exendin-4 (GLP-1 Receptor) positron emission tomography/CT.

NO-donating tacrine hybrid compounds improve scopolamine-induced cognition impairment and show less hepatotoxicity

Oral Chemical Burns Reported to the Poisons Information Centre in Erfurt, Germany, from 1997 to 2014.

Pasireotide and octreotide stimulate distinct patterns of sst2A somatostatin receptor phosphorylation

Pharmacological and toxicological testing of the enantiomers of two chiral fomocaine alkylmorpholine derivatives in comparison to their in vitro interactions on drug metabolism in rats

Physical exercise induces specific adaptations resulting in reduced organ injury and mortality during severe polymicrobial sepsis

Precision-cut liver slices from rats of different ages: basal cytochrome P450-dependent monooxygenase activities and inducibility

Primary-like human hepatocytes genetically engineered to obtain proliferation competence display hepatic differentiation characteristics in monolayer and organotypical spheroid cultures

Prospective assessment of hepatic function and mechanisms of dysfunction in the critically ill.

Proteasome inhibitor bortezomib enhances the effect of standard chemotherapy in small cell lung cancer.

Protective Effect of Casperome®, an Orally Bioavailable Frankincense Extract, on Lipopolysaccharide- Induced Systemic Inflammation in Mice.

Reassessment of endothelin receptor A expression in normal and neoplastic human tissues using the novel rabbit monoclonal antibody UMB-8

Reassessment of sst 5 Somatostatin Receptor Expression in Normal and Neoplastic Human Tissues Using the Novel Rabbit Monoclonal Antibody UMB-4

Reassessment of sst3 somatostatin receptor expression in human normal and neoplastic tissues using the novel rabbit monoclonal antibody UMB-5.

Reevaluation of sst1 somatostatin receptor expression in human normal and neoplastic tissues using the novel rabbit monoclonal antibody UMB-7

SSTR3 is a putative target for the medical treatment of gonadotroph adenomas of the pituitary

Single and chronic administration of ciprofibrate or of ciprofibrate-glycinate in male Fischer 344 rats: comparison of the effects on morphological and biochemical parameters in liver and blood.

Somatostatin analogs modulate AIP in somatotroph adenomas: the role of the ZAC1 pathway.