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List of works by Simone A Joosten

100 years of the Bacillus Calmette-Guérin vaccine

scientific article published in 2021

A helicopter perspective on TB biomarkers: pathway and process based analysis of gene expression data provides new insight into TB pathogenesis

scientific article

A novel liposomal adjuvant system, CAF01, promotes long-lived Mycobacterium tuberculosis-specific T-cell responses in human

scientific article published on 30 October 2014

A novel view on the pathogenesis of complications after intravesical BCG for bladder cancer

scientific article published on 17 May 2018

Acquired immunodeficiencies and tuberculosis: focus on HIV/AIDS and diabetes mellitus

scientific article

Adoptive transfer of primed CD4+ T-lymphocytes induces pattern of chronic allograft nephropathy in a nude rat model

scientific article published in April 2005

Ag85B-ESAT-6 adjuvanted with IC31® promotes strong and long-lived Mycobacterium tuberculosis specific T cell responses in volunteers with previous BCG vaccination or tuberculosis infection

scientific article

An Internet-Based Psychological Intervention With a Serious Game to Improve Vitality, Psychological and Physical Condition, and Immune Function in Healthy Male Adults: Randomized Controlled Trial

scientific article published on 24 July 2020

An imaging mass cytometry immunophenotyping panel for non-human primate tissues

scientific article published in 2022

Analyzing the impact of Mycobacterium tuberculosis infection on primary human macrophages by combined exploratory and targeted metabolomics

scientific article published on 27 April 2020

Anti-tubular basement membrane antibodies and giant cell formation in a model of chronic renal allograft rejection

scientific article

Antibodies against mesangial cells in a rat model of chronic renal allograft rejection

scientific article published on 08 February 2005

Antibody Subclass and Glycosylation Shift Following Effective TB Treatment

scientific article published on 05 July 2021

Antibody glycosylation in inflammation, disease and vaccination

scientific article published on 11 June 2018

Antibody response against perlecan and collagen types IV and VI in chronic renal allograft rejection in the rat.

scientific article published on April 2002

Antibody response against the glomerular basement membrane protein agrin in patients with transplant glomerulopathy

scientific article published on 01 February 2005

Antigen presentation by MHC-E: a putative target for vaccination?

scientific article published in 2022

Applying the FAIR principles to data in a hospital: challenges and opportunities in a pandemic

scientific article published on 25 April 2022

Atypical Human Effector/Memory CD4 T Cells With a Naive-Like Phenotype

B-Cells and Antibodies as Contributors to Effector Immune Responses in Tuberculosis

scientific article published in 2021

BCG lowers plasma cholesterol levels and delays atherosclerotic lesion progression in mice.

scientific article published on 19 May 2016

Biomarkers Can Identify Pulmonary Tuberculosis in HIV-infected Drug Users Months Prior to Clinical Diagnosis

scientific article published on 2 December 2014

Biomarkers to identify <i>Mycobacterium tuberculosis</i> infection among borderline QuantiFERON results

scientific article published in 2022

CD39 is involved in mediating suppression by Mycobacterium bovis BCG-activated human CD8(+) CD39(+) regulatory T cells.

scientific article published on 29 May 2013

CD8+ regulatory T cells, and not CD4+ T cells, dominate suppressive phenotype and function after in vitro live Mycobacterium bovis-BCG activation of human cells

scientific article

Characteristics of HLA-E Restricted T-Cell Responses and Their Role in Infectious Diseases

scientific article

Chronic rejection in renal transplantation

scientific article published in 2003

Chronic rejection in renal transplantation

scientific article published in 2004

Chronic renal allograft rejection: pathophysiologic considerations

scientific article

Clinical immunology and multiplex biomarkers of human tuberculosis

scientific article

Comment on "CCR5 dictates the equilibrium of proinflammatory IL-17+ and regulatory Foxp3+ T cells in fungal infections"

scientific article published on 01 August 2010

Complement Component C1q as Serum Biomarker to Detect Active Tuberculosis

scientific article published on 23 October 2018

Complement component C1q as serum biomarker to detect active tuberculosis

scientific article published in 2018

Correlates of tuberculosis risk: predictive biomarkers for progression to active tuberculosis

scientific article

Cross-laboratory evaluation of multiplex bead assays including independent common reference standards for immunological monitoring of observational and interventional human studies

scientific article published in PLoS ONE

Detailed characterization of human Mycobacterium tuberculosis specific HLA-E restricted CD8+ T cells

scientific article published on 9 November 2017

Editorial: Beyond Th1: Novel concepts in tuberculosis vaccine immunology

scientific article published in 2022

Effectiveness of Stress-Reducing Interventions on the Response to Challenges to the Immune System: A Meta-Analytic Review

scientific article published on 06 August 2019

Effects of BCG vaccination on donor unrestricted T cells in two prospective cohort studies

scientific article published in 2022

Elderly subjects have a delayed antibody response and prolonged viraemia following yellow fever vaccination: a prospective controlled cohort study

scientific article

Evidence for the heterologous benefits of prior BCG vaccination on COVISHIELD™ vaccine-induced immune responses in SARS-CoV-2 seronegative young Indian adults

scientific article published in 2022

Expression and production of the SERPING1-encoded endogenous complement regulator C1-inhibitor in multiple cohorts of tuberculosis patients

scientific article published on 13 March 2020

Extensive flow cytometric immunophenotyping of human <scp>PBMC</scp> incorporating detection of chemokine receptors, cytokines and tetramers

scientific article published in 2023

Fixed Dosing of Tocilizumab in ICU Admitted COVID-19 Patients Is a Superior Choice Compared to Bodyweight Based Dosing; An Observational Population Pharmacokinetic and Pharmacodynamic Study

scientific article published in 2021

Genetic profiling of aortic allografts: prothymosin alpha as potential target?

scientific article published on 01 August 2005

Guidance for Studies Evaluating the Accuracy of Biomarker-Based Nonsputum Tests to Diagnose Tuberculosis

scientific article published on 01 October 2019

Harnessing donor unrestricted T-cells for new vaccines against tuberculosis

scientific article published on 27 April 2019

Host biomarker-based quantitative rapid tests for detection and treatment monitoring of tuberculosis and COVID-19

scientific article published in 2023

Human CD4 T-Cells With a Naive Phenotype Produce Multiple Cytokines During Mycobacterium Tuberculosis Infection and Correlate With Active Disease.

scientific article

Human CD4 and CD8 regulatory T cells in infectious diseases and vaccination

scientific article published on 07 October 2008

Human CD8 T lymphocytes recognize Mycobacterium tuberculosis antigens presented by HLA-E during active tuberculosis and express type 2 cytokines

scientific article

Human CD8+ T-cells recognizing peptides from Mycobacterium tuberculosis (Mtb) presented by HLA-E have an unorthodox Th2-like, multifunctional, Mtb inhibitory phenotype and represent a novel human T-cell subset.

scientific article

Human anti-inflammatory macrophages induce Foxp3+ GITR+ CD25+ regulatory T cells, which suppress via membrane-bound TGFbeta-1.

scientific article published in August 2008

Identification of HLA-E Binding -Derived Epitopes through Improved Prediction Models

scholarly article

Identification of a human CD8+ regulatory T cell subset that mediates suppression through the chemokine CC chemokine ligand 4.

scholarly article

Identification of major factors influencing ELISpot-based monitoring of cellular responses to antigens from Mycobacterium tuberculosis

scientific article

Identification of probable early-onset biomarkers for tuberculosis disease progression

scientific article

Immunoglobulin G1 Fc glycosylation as an early hallmark of severe COVID-19

scientific article published on 22 March 2022

Immunologic risk factors and glomerular C4d deposits in chronic transplant glomerulopathy

scientific article published in June 2004

Immunological characterization of latent tuberculosis infection in a low endemic country

scientific article published on 4 July 2017

Innovative Strategies to Identify M. tuberculosis Antigens and Epitopes Using Genome-Wide Analyses

scientific article

Intracellular Cytokine Staining and Flow Cytometry: Considerations for Application in Clinical Trials of Novel Tuberculosis Vaccines

scientific article published on 14 September 2015

Inverse correlation between serum complement component C1q levels and whole blood type-1 interferon signature in active tuberculosis and QuantiFERON-positive uveitis: implications for diagnosis

scientific article published on 16 October 2020

KLRG1 and PD-1 expression are increased on T-cells following tuberculosis-treatment and identify cells with different proliferative capacities in BCG-vaccinated adults

scientific article

Long-lasting tuberculous pleurisy

scientific article published on 25 May 2017

Lung epithelial cells interact with immune cells and bacteria to shape the microenvironment in tuberculosis

scientific article published in 2022

MHC Ib molecule Qa-1 presents Mycobacterium tuberculosis peptide antigens to CD8+ T cells and contributes to protection against infection.

scientific article

Mobilizing unconventional T cells

scientific article published on 01 October 2019

Multifunctional CD4(+) T cells correlate with active Mycobacterium tuberculosis infection

scientific article published in August 2010

Mycobacterial growth inhibition is associated with trained innate immunity

scientific article published on 20 February 2018

Mycobacterium bovis BCG Vaccination Induces Divergent Proinflammatory or Regulatory T Cell Responses in Adults

scientific article published on 6 May 2015

Mycobacterium tuberculosis peptides presented by HLA-E molecules are targets for human CD8 T-cells with cytotoxic as well as regulatory activity

scientific article

Non-HLA humoral immunity and chronic kidney-graft loss

scientific article published on 01 April 2005

Non-lytic antibiotic treatment in community-acquired pneumococcal pneumonia does not attenuate inflammation: the PRISTINE trial

scientific article published on 01 August 2019

Oxidized low-density lipoprotein (oxLDL) supports Mycobacterium tuberculosis survival in macrophages by inducing lysosomal dysfunction

scientific article published on 18 April 2019

Pathogenesis of chronic allograft rejection

scientific article

Patients with Concurrent Tuberculosis and Diabetes Have a Pro-Atherogenic Plasma Lipid Profile.

scientific article

Patients with Tuberculosis Have a Dysfunctional Circulating B-Cell Compartment, Which Normalizes following Successful Treatment

scientific article

Peptide Binding to HLA-E Molecules in Humans, Nonhuman Primates, and Mice Reveals Unique Binding Peptides but Remarkably Conserved Anchor Residues

scientific article published on 05 October 2020

Plasma metabolomics in tuberculosis patients with and without concurrent type 2 diabetes at diagnosis and during antibiotic treatment

scientific article published on 10 December 2019

Regulatory T-Cells at the Interface between Human Host and Pathogens in Infectious Diseases and Vaccination

scientific article

Safety and immunogenicity of the novel H4:IC31 tuberculosis vaccine candidate in BCG-vaccinated adults: Two phase I dose escalation trials

scientific article

Serum Biomarker Profile Including CCL1, CXCL10, VEGF, and Adenosine Deaminase Activity Distinguishes Active From Remotely Acquired Latent Tuberculosis

scientific article published in 2021

Systemic and pulmonary C1q as biomarker of progressive disease in experimental non-human primate tuberculosis

scientific article published on 14 April 2020

Telomere shortening and cellular senescence in a model of chronic renal allograft rejection

scientific article published on April 2003

The antimicrobial peptide hLF1-11 drives monocyte-dendritic cell differentiation toward dendritic cells that promote antifungal responses and enhance Th17 polarization

scientific article published on 19 January 2012

The effect of hyperglycaemia on in vitro cytokine production and macrophage infection with Mycobacterium tuberculosis

scientific article published on 9 February 2015

The effects of a psychological intervention directed at optimizing immune function: study protocol for a randomized controlled trial

scientific article published on 26 May 2017

The other Janus face of Qa-1 and HLA-E: diverse peptide repertoires in times of stress

scientific article published on 27 July 2010

The pathobiology of chronic allograft nephropathy: immune-mediated damage and accelerated aging

scientific article published on May 2004

The role of donor‐unrestricted T‐cells, innate lymphoid cells, and NK cells in anti‐mycobacterial immunity

scientific article published in 2021

Towards Fixed Dosing of Tocilizumab in ICU-Admitted COVID-19 Patients: Results of an Observational Population Pharmacokinetic and Descriptive Pharmacodynamic Study

scientific article published in 2021

Transcriptional profiles predict treatment outcome in patients with tuberculosis and diabetes at diagnosis and at two weeks after initiation of anti-tuberculosis treatment

scientific article published in 2022

Tuberculosis Biomarkers: From Diagnosis to Protection

scientific article

Tuberculosis causes highly conserved metabolic changes in human patients, mycobacteria-infected mice and zebrafish larvae

scientific article published on 15 July 2020

Vaccination with a Hybrid 1 (H1) fusion protein combined with a liposomal adjuvant (CAF01) induced antigen specific T-cells 3 years post vaccination in a human clinical trial. (VAC7P.971)

scientific article published in 2014

[COVID-19-associated hyperinflammatory state in a 15-year-old female patient]

scientific article published on 22 October 2020

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