List of works - Miyuki Azuma

A critical role for the programmed death ligand 1 in fetomaternal tolerance

scientific article

A novel beta 4, alpha 6 integrin-associated epithelial cell antigen involved in natural killer cell and antigen-specific cytotoxic T lymphocyte cytotoxicity ⬇️

scientific article published on December 1, 1991

An Interleukin-33-Mast Cell-Interleukin-2 Axis Suppresses Papain-Induced Allergic Inflammation by Promoting Regulatory T Cell Numbers.

scientific article

Anti-CD3 treatment up-regulates programmed cell death protein-1 expression on activated effector T cells and severely impairs their inflammatory capacity

scientific article

Antibodies against B7-DC with differential binding properties exert opposite effects

scientific article published on 01 February 2012

B7-1 mediated costimulation regulates pancreatic autoimmunity

scientific article

B7-H1 overexpression regulates epithelial-mesenchymal transition and accelerates carcinogenesis in skin

scientific article published on 15 December 2010

B70 antigen is a second ligand for CTLA-4 and CD28 ⬇️

scientific article published on November 4, 1993

Blockade Of PD-1 Attenuated Postsepsis Aspergillosis Via The Activation of IFN-γ and The Dampening of IL-10

scientific article published on 01 April 2020

Blockade of B7-H1 Suppresses the Development of Chronic Intestinal Inflammation ⬇️

scientific article published on October 15, 2003

CD28 interaction with B7 costimulates primary allogeneic proliferative responses and cytotoxicity mediated by small, resting T lymphocytes ⬇️

scientific article published on February 1, 1992

CD4 T-cell help programs a change in CD8 T-cell function enabling effective long-term control of murine gammaherpesvirus 68: role of PD-1-PD-L1 interactions.

scientific article

Characterization of rat CD80 and CD86 by molecular cloning and mAb ⬇️

scientific article published on July 1, 1997

Clinical significance of programmed death-1 ligand-1 and programmed death-1 ligand-2 expression in human esophageal cancer

scientific article (publication date: 15 April 2005)

Coexpression of Tim-3 and PD-1 identifies a CD8+ T-cell exhaustion phenotype in mice with disseminated acute myelogenous leukemia

scientific article

Cooperative B7-1/2 (CD80/CD86) and B7-DC costimulation of CD4+ T cells independent of the PD-1 receptor

scientific article

Critical role of PD-L1 expression on non-tumor cells rather than on tumor cells for effective anti-PD-L1 immunotherapy in a transplantable mouse hematopoietic tumor model

scientific article published on 22 February 2020

Critical role of the programmed death-1 (PD-1) pathway in regulation of experimental autoimmune encephalomyelitis

scientific article

Crucial roles of B7-H1 and B7-DC expressed on mesenteric lymph node dendritic cells in the generation of antigen-specific CD4+Foxp3+ regulatory T cells in the establishment of oral tolerance

scientific article

Differential binding properties of B7-H1 and B7-DC to programmed death-1

scientific article (publication date: August 2003)

Differential contribution of three immune checkpoint (VISTA, CTLA-4, PD-1) pathways to antitumor responses against squamous cell carcinoma

scientific article

Enhancement of effector CD8+ T-cell function by tumour-associated B7-H3 and modulation of its counter-receptor triggering receptor expressed on myeloid cell-like transcript 2 at tumour sites

scientific article

Expression and function of the B and T lymphocyte attenuator (BTLA/CD272) on human T cells

scientific article

Expression of perforin and cytolytic potential of human peripheral blood lymphocyte subpopulations

scientific article published on September 1, 1992

Expression of programmed death 1 ligands by murine T cells and APC

scientific article (publication date: 15 November 2002)

Functional CD86 (B7-2/B70) is predominantly expressed on Langerhans cells in atopic dermatitis ⬇️

scientific article published on 01 June 1997

Functional expression of B7/BB1 on activated T lymphocytes ⬇️

scientific article published on March 1, 1993

HTLV‐I‐infected T cells activate autologous CD4+ T cells susceptible to HTLV‐I infection in a co‐stimulatory molecule‐dependent fashion ⬇️

scientific article published on June 1, 1997

Host programmed death ligand 1 is dominant over programmed death ligand 2 expression in regulating graft-versus-host disease lethality

scientific article published on 12 September 2013

How Two Brains Make One Synchronized Mind in the Inferior Frontal Cortex: fNIRS-Based Hyperscanning During Cooperative Singing

scientific article

Immunoregulatory molecule B7-H1 (CD274) contributes to skin carcinogenesis

scientific article published on 05 July 2011

Insulin-induced remission in new-onset NOD mice is maintained by the PD-1-PD-L1 pathway.

scientific article

Intact B7-H3 signaling promotes allograft prolongation through preferential suppression of Th1 effector responses

scientific article published on September 2012

Interactions between PD-1 and PD-L1 promote tolerance by blocking the TCR-induced stop signal.

scientific article

Interferon-gamma differentially regulates CD80 (B7-1) and CD86 (B7-2/B70) expression on human Langerhans cells ⬇️

scientific article published on 01 June 1997

Intrinsic and extrinsic control of expression of the immunoregulatory molecule PD-L1 in epithelial cells and squamous cell carcinoma

scientific article

Involvement of inducible costimulator-B7 homologous protein costimulatory pathway in murine lupus nephritis

scientific article (publication date: 15 September 2003)

Keratinocyte-associated B7-H1 directly regulates cutaneous effector CD8+ T cell responses

scientific article published on 02 April 2010

PD-1/PD-L blockade prevents anergy induction and enhances the anti-tumor activities of glycolipid-activated invariant NKT cells

scientific article

PDL1 is required for peripheral transplantation tolerance and protection from chronic allograft rejection

scientific article

PI3K-Akt pathway enhances the differentiation of interleukin-27-induced type 1 regulatory T cells.

scientific article

Paracrine IL-33 stimulation enhances lipopolysaccharide-mediated macrophage activation

scientific journal article

Plasmacytoid dendritic cells from mouse tumor-draining lymph nodes directly activate mature Tregs via indoleamine 2,3-dioxygenase

scientific article published in September 2007

Preferential contribution of B7‐H1 to programmed death‐1‐mediated regulation of hapten‐specific allergic inflammatory responses ⬇️

scientific article published on October 1, 2003

Program death-1 signaling and regulatory T cells collaborate to resist the function of adoptively transferred cytotoxic T lymphocytes in advanced acute myeloid leukemia.

scientific article

Programmed cell death 1 forms negative costimulatory microclusters that directly inhibit T cell receptor signaling by recruiting phosphatase SHP2.

scientific article

Programmed death-1-programmed death-L1 interaction is essential for induction of regulatory cells by intratracheal delivery of alloantigen

scientific article

RANKL expression, function, and therapeutic targeting in multiple myeloma and chronic lymphocytic leukemia

scientific article

Role of the glucocorticoid-induced TNFR-related protein (GITR)-GITR ligand pathway in innate and adaptive immunity

scientific article published on January 2010

Roles of programmed death-1 (PD-1)/PD-1 ligands pathway in the development of murine acute myocarditis caused by coxsackievirus B3.

scientific article

Small interfering RNA against CD86 during allergen challenge blocks experimental allergic asthma

scientific article

Sugar catabolism regulated by light- and nitrogen-status in the cyanobacterium Synechocystis sp. PCC 6803.

scientific article published on 22 February 2007

Th2 cell-intrinsic hypo-responsiveness determines susceptibility to helminth infection

scientific article

Th2 responses to helminth parasites can be therapeutically enhanced by, but are not dependent upon, GITR-GITR ligand costimulation in vivo

scientific article

The expression and function of costimulatory molecules B7H and B7-H1 on colonic epithelial cells

scientific article

The link between the PDL1 costimulatory pathway and Th17 in fetomaternal tolerance.

scientific article

The novel costimulatory programmed death ligand 1/B7.1 pathway is functional in inhibiting alloimmune responses in vivo

scientific article

The programmed death-1 (PD-1) pathway regulates autoimmune diabetes in nonobese diabetic (NOD) mice

scientific article

Topical application of cream-emulsified CD86 siRNA ameliorates allergic skin disease by targeting cutaneous dendritic cells

scientific article published on 06 May 2008

Topical application of siRNA targeting cutaneous dendritic cells in allergic skin disease

scientific article published on 01 January 2010

Triggering receptor expressed on myeloid cell-like transcript 2 (TLT-2) is a counter-receptor for B7-H3 and enhances T cell responses

scientific article

List of works by Miyuki Azuma

A critical role for the programmed death ligand 1 in fetomaternal tolerance

A novel beta 4, alpha 6 integrin-associated epithelial cell antigen involved in natural killer cell and antigen-specific cytotoxic T lymphocyte cytotoxicity ⬇️

An Interleukin-33-Mast Cell-Interleukin-2 Axis Suppresses Papain-Induced Allergic Inflammation by Promoting Regulatory T Cell Numbers.

Anti-CD3 treatment up-regulates programmed cell death protein-1 expression on activated effector T cells and severely impairs their inflammatory capacity

Antibodies against B7-DC with differential binding properties exert opposite effects

B7-1 mediated costimulation regulates pancreatic autoimmunity

B7-H1 overexpression regulates epithelial-mesenchymal transition and accelerates carcinogenesis in skin

B70 antigen is a second ligand for CTLA-4 and CD28 ⬇️

Blockade Of PD-1 Attenuated Postsepsis Aspergillosis Via The Activation of IFN-γ and The Dampening of IL-10

Blockade of B7-H1 Suppresses the Development of Chronic Intestinal Inflammation ⬇️

CD28 interaction with B7 costimulates primary allogeneic proliferative responses and cytotoxicity mediated by small, resting T lymphocytes ⬇️

CD4 T-cell help programs a change in CD8 T-cell function enabling effective long-term control of murine gammaherpesvirus 68: role of PD-1-PD-L1 interactions.

Characterization of rat CD80 and CD86 by molecular cloning and mAb ⬇️

Clinical significance of programmed death-1 ligand-1 and programmed death-1 ligand-2 expression in human esophageal cancer

Coexpression of Tim-3 and PD-1 identifies a CD8+ T-cell exhaustion phenotype in mice with disseminated acute myelogenous leukemia

Cooperative B7-1/2 (CD80/CD86) and B7-DC costimulation of CD4+ T cells independent of the PD-1 receptor

Critical role of PD-L1 expression on non-tumor cells rather than on tumor cells for effective anti-PD-L1 immunotherapy in a transplantable mouse hematopoietic tumor model

Critical role of the programmed death-1 (PD-1) pathway in regulation of experimental autoimmune encephalomyelitis

Crucial roles of B7-H1 and B7-DC expressed on mesenteric lymph node dendritic cells in the generation of antigen-specific CD4+Foxp3+ regulatory T cells in the establishment of oral tolerance

Differential binding properties of B7-H1 and B7-DC to programmed death-1

Differential contribution of three immune checkpoint (VISTA, CTLA-4, PD-1) pathways to antitumor responses against squamous cell carcinoma

Enhancement of effector CD8+ T-cell function by tumour-associated B7-H3 and modulation of its counter-receptor triggering receptor expressed on myeloid cell-like transcript 2 at tumour sites

Expression and function of the B and T lymphocyte attenuator (BTLA/CD272) on human T cells

Expression of perforin and cytolytic potential of human peripheral blood lymphocyte subpopulations

Expression of programmed death 1 ligands by murine T cells and APC

Functional CD86 (B7-2/B70) is predominantly expressed on Langerhans cells in atopic dermatitis ⬇️

Functional expression of B7/BB1 on activated T lymphocytes ⬇️

HTLV‐I‐infected T cells activate autologous CD4+ T cells susceptible to HTLV‐I infection in a co‐stimulatory molecule‐dependent fashion ⬇️

Host programmed death ligand 1 is dominant over programmed death ligand 2 expression in regulating graft-versus-host disease lethality

How Two Brains Make One Synchronized Mind in the Inferior Frontal Cortex: fNIRS-Based Hyperscanning During Cooperative Singing

Immunoregulatory molecule B7-H1 (CD274) contributes to skin carcinogenesis

Insulin-induced remission in new-onset NOD mice is maintained by the PD-1-PD-L1 pathway.

Intact B7-H3 signaling promotes allograft prolongation through preferential suppression of Th1 effector responses

Interactions between PD-1 and PD-L1 promote tolerance by blocking the TCR-induced stop signal.

Interferon-gamma differentially regulates CD80 (B7-1) and CD86 (B7-2/B70) expression on human Langerhans cells ⬇️

Intrinsic and extrinsic control of expression of the immunoregulatory molecule PD-L1 in epithelial cells and squamous cell carcinoma

Involvement of inducible costimulator-B7 homologous protein costimulatory pathway in murine lupus nephritis

Keratinocyte-associated B7-H1 directly regulates cutaneous effector CD8+ T cell responses

PD-1/PD-L blockade prevents anergy induction and enhances the anti-tumor activities of glycolipid-activated invariant NKT cells

PDL1 is required for peripheral transplantation tolerance and protection from chronic allograft rejection

PI3K-Akt pathway enhances the differentiation of interleukin-27-induced type 1 regulatory T cells.

Paracrine IL-33 stimulation enhances lipopolysaccharide-mediated macrophage activation

Plasmacytoid dendritic cells from mouse tumor-draining lymph nodes directly activate mature Tregs via indoleamine 2,3-dioxygenase

Preferential contribution of B7‐H1 to programmed death‐1‐mediated regulation of hapten‐specific allergic inflammatory responses ⬇️

Program death-1 signaling and regulatory T cells collaborate to resist the function of adoptively transferred cytotoxic T lymphocytes in advanced acute myeloid leukemia.

Programmed cell death 1 forms negative costimulatory microclusters that directly inhibit T cell receptor signaling by recruiting phosphatase SHP2.

Programmed death-1-programmed death-L1 interaction is essential for induction of regulatory cells by intratracheal delivery of alloantigen

RANKL expression, function, and therapeutic targeting in multiple myeloma and chronic lymphocytic leukemia

Role of the glucocorticoid-induced TNFR-related protein (GITR)-GITR ligand pathway in innate and adaptive immunity

Roles of programmed death-1 (PD-1)/PD-1 ligands pathway in the development of murine acute myocarditis caused by coxsackievirus B3.

Small interfering RNA against CD86 during allergen challenge blocks experimental allergic asthma

Sugar catabolism regulated by light- and nitrogen-status in the cyanobacterium Synechocystis sp. PCC 6803.

Th2 cell-intrinsic hypo-responsiveness determines susceptibility to helminth infection

Th2 responses to helminth parasites can be therapeutically enhanced by, but are not dependent upon, GITR-GITR ligand costimulation in vivo

The expression and function of costimulatory molecules B7H and B7-H1 on colonic epithelial cells

The link between the PDL1 costimulatory pathway and Th17 in fetomaternal tolerance.

The novel costimulatory programmed death ligand 1/B7.1 pathway is functional in inhibiting alloimmune responses in vivo

The programmed death-1 (PD-1) pathway regulates autoimmune diabetes in nonobese diabetic (NOD) mice

Topical application of cream-emulsified CD86 siRNA ameliorates allergic skin disease by targeting cutaneous dendritic cells

Topical application of siRNA targeting cutaneous dendritic cells in allergic skin disease

Triggering receptor expressed on myeloid cell-like transcript 2 (TLT-2) is a counter-receptor for B7-H3 and enhances T cell responses