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List of works by Youssef Daali

A Randomized, Controlled Trial Validates a Peripheral Supra-Additive Antihyperalgesic Effect of a Paracetamol-Ketorolac Combination ⬇️

scientific article published on 06 July 2011

A cocktail approach for assessing the in vitro activity of human cytochrome P450s: an overview of current methodologies

scientific article published on 28 March 2014

A simplified analytical method for a phenotyping cocktail of major CYP450 biotransformation routes

scientific article published in September 2004

A simplified method for busulfan monitoring using dried blood spot in combination with liquid chromatography/tandem mass spectrometry

scientific article published on 01 June 2012

An extensive cocktail approach for rapid risk assessment of in vitro CYP450 direct reversible inhibition by xenobiotic exposure

scientific article published on 19 April 2016

Analgesics in patients with hepatic impairment: pharmacology and clinical implications.

scientific article published in August 2012

Aspirin response: Differences in serum thromboxane B2 levels between clinical studies.

scientific article published on 13 August 2015

Automated system for on-line desorption of dried blood spots applied to LC/MS/MS pharmacokinetic study of flurbiprofen and its metabolite

scientific article published on 01 January 2011

Characterization of oxycodone in vitro metabolism by human cytochromes P450 and UDP-glucuronosyltransferases.

scientific article published on 26 September 2016

Codeine intoxication associated with ultrarapid CYP2D6 metabolism

scientific article

Comparing Dried Blood Spots and Plasma Concentrations for Busulfan Therapeutic Drug Monitoring in Children

scientific article published on 01 February 2020

Complex Drug-Drug-Gene-Disease Interactions Involving Cytochromes P450: Systematic Review of Published Case Reports and Clinical Perspectives.

scientific article published on 17 April 2018

Contribution of exome sequencing to the identification of genes involved in the response to clopidogrel in cardiovascular patients

scientific article published on 20 February 2020

Cytochrome P450 1A2 activity and incidence of thyroid disease and cancer after chronic or acute exposure to dioxins

scientific article published on 08 November 2019

Detection of busulfan adducts on proteins.

scientific article

Development of an LC-MS/MS Method for the Assessment of Selected Active Pharmaceuticals and Metabolites in Wastewaters of a Swiss University Hospital

scientific article published in January 2015

Dual reuptake inhibitor milnacipran and spinal pain pathways in fibromyalgia patients: a randomized, double-blind, placebo-controlled trial

scientific article published in September 2013

Dynamics of active pharmaceutical ingredients loads in a Swiss university hospital wastewaters and prediction of the related environmental risk for the aquatic ecosystems.

scientific article published on 11 January 2016

Evaluation of Mutual Drug-Drug Interaction within Geneva Cocktail for Cytochrome P450 Phenotyping using Innovative Dried Blood Sampling Method

scientific article published on 24 March 2016

Evaluation of Phenotypic and Genotypic Variations of Drug Metabolising Enzymes and Transporters in Chronic Pain Patients Facing Adverse Drug Reactions or Non-Response to Analgesics: A Retrospective Study

scientific article published on 27 October 2020

Evidence-Based Choice of P2Y12 Inhibitors in End Stage Renal Disease Patients: A Mini-Review

scientific article published on January 2015

GABAergic modulation of secondary hyperalgesia: A randomized controlled 4-way crossover trial with the α2-subunit preferring GABA positive allosteric modulator, N-desmethyl-clobazam in healthy volunteers

scientific article published on 14 March 2020

Genotype-sensitive reversible and time-dependent CYP2D6 inhibition in human liver microsomes

scientific article published on 11 October 2018

Impact of Boosted Antiretroviral Therapy on the Pharmacokinetics and Efficacy of Clopidogrel and Prasugrel Active Metabolites

scientific article published on 16 February 2018

Impact of CYP2D6 Functional Allelic Variations on Phenoconversion and Drug-Drug Interactions.

scientific article published on 23 September 2017

Impact of acute inflammation on cytochromes P450 activity assessed by the Geneva Cocktail

scientific article published on 20 December 2020

Incorporation of flurbiprofen in a 4-drug cytochrome p450 phenotyping cocktail

scientific article published on 25 April 2014

Influence of ABCB1 gene polymorphisms and P-glycoprotein activity on cyclosporine pharmacokinetics in peripheral blood mononuclear cells in healthy volunteers

scientific article published in April 2008

Influence of CYP2D6 activity on pre-emptive analgesia by the N-methyl-D-aspartate antagonist dextromethorphan in a randomized controlled trial of acute pain

scientific article published on 01 January 2013

Interaction between Fexofenadine and CYP Phenotyping Probe Drugs in Geneva Cocktail

scientific article published on 02 October 2019

Intestinal permeability and P-glycoprotein-mediated efflux transport of ticagrelor in Caco-2 monolayer cells

scientific article published on 14 July 2016

Intraocular penetration of penciclovir after oral administration of famciclovir: a population pharmacokinetic model

scientific article

Is pain temporary and glory for ever? Detection of tramadol using dried blood spot in cycling competitions

scientific article published on 27 August 2020

Mixing drugs and genetics: a complex hemorrhagic cocktail

scientific article published on 25 August 2020

On-line desorption of dried blood spots coupled to hydrophilic interaction/reversed-phase LC/MS/MS system for the simultaneous analysis of drugs and their polar metabolites

scientific article published in March 2010

Optimized low-dose combinatorial drug treatment boosts selectivity and efficacy of colorectal carcinoma treatment

scientific article published on 05 October 2020

P-glycoprotein is not involved in the differential oral potency of naloxone and naltrexone

scientific article published on 28 July 2009

Perioperative intravenous low-dose ketamine for neuropathic pain after major lower back surgery: A randomized, placebo-controlled study

scientific article published on 09 December 2019

Pharmacogenomics of Oral Antithrombotic Drugs

scientific article

Pharmacokinetic Interaction Between Prasugrel and Ritonavir in Healthy Volunteers ⬇️

scientific article published on October 5, 2012

Pharmacokinetic and pharmacodynamic properties of buprenorphine after a single intravenous administration in healthy volunteers: a randomized, double-blind, placebo-controlled, crossover study

scientific article published in August 2007

Pharmacokinetic-pharmacodynamic modelling of opioids in healthy human volunteers. a minireview ⬇️

scientific article published on November 9, 2011

Phenotypic Assessment of Drug Metabolic Pathways and P-Glycoprotein in Patients Treated With Antidepressants in an Ambulatory Setting

scientific article published on 01 March 2018

Phenotyping of CYP450 in human liver microsomes using the cocktail approach

scientific article published on 4 June 2014

Phenotyping of Human CYP450 Enzymes by Endobiotics: Current Knowledge and Methodological Approaches

scientific article published on 01 November 2019

Prediction by pharmacogenetics of safety and efficacy of non-steroidal anti- inflammatory drugs: a review

scientific article published on March 2014

Prediction of drug-drug interactions using physiologically-based pharmacokinetic models of CYP450 modulators included in Simcyp software.

scientific article published on 28 September 2017

Predictive value of CYP3A and ABCB1 phenotyping probes for the pharmacokinetics of sunitinib: the ClearSun study

scientific article published in March 2014

Prioritization methodology for the monitoring of active pharmaceutical ingredients in hospital effluents.

scientific article

Prioritization of Active Pharmaceutical Ingredients in Hospital Wastewater

scientific article published in 2017

Real-time monitoring of exhaled drugs by mass spectrometry

scientific article

Ritonavir inhibits the two main prasugrel bioactivation pathways in vitro: a potential drug-drug interaction in HIV patients.

scientific article published on 6 May 2011

Rivaroxaban-Induced Hemorrhage Associated with ABCB1 Genetic Defect.

scientific article published on 19 December 2016

Role of P-glycoprotein in the uptake/efflux transport of oral vitamin K antagonists and rivaroxaban through the Caco-2 cell model

scientific article published on 25 June 2013

Screening for genotypic and phenotypic variations in CYP450 activity in patients with therapeutic problems in a psychiatric setting, a retrospective study

scientific article published in July 2016

Serotonin syndrome following drug-drug interactions and CYP2D6 and CYP2C19 genetic polymorphisms in an HIV-infected patient

scientific article

Severe Vincristine-induced Neuropathic Pain in a CYP3A5 Nonexpressor With Reduced CYP3A4/5 Activity: Case Study.

scientific article

Severe and persistent morphine-induced respiratory depression associated with ATP-Binding Cassette Subfamily B Member 1 and catechol-O-methyltransferase genetic defects: A case report

scientific article published on 01 July 2018

Simultaneous LC-MS/MS quantification of P-glycoprotein and cytochrome P450 probe substrates and their metabolites in DBS and plasma

scientific article published in January 2014

The Association of Combined GSTM1 and CYP2C9 Genotype Status with the Occurrence of Hemorrhagic Cystitis in Pediatric Patients Receiving Myeloablative Conditioning Regimen Prior to Allogeneic Hematopoietic Stem Cell Transplantation.

scientific article published on 11 July 2017

The tyrosine kinase inhibitor nilotinib inhibits SARS-CoV-2 In Vitro

scientific article published on 24 November 2020

Therapeutic Drug Monitoring of Busulfan for the Management of Pediatric Patients: Cross-Validation of Methods and Long-Term Performance.

scientific article

Therapeutic drug monitoring of voriconazole: a case report of multiple drug interactions in a patient with an increased CYP2C19 activity

scientific article

Toward precision medicine in pediatric population using cytochrome P450 phenotyping approaches and physiologically based pharmacokinetic modeling

scientific article published on 10 October 2019

Towards Personalized Antithrombotic Treatments: Focus on P2Y12 Inhibitors and Direct Oral Anticoagulants

scientific article published on 01 December 2019

Transcriptional Regulation of CYP2C19 and its Role in Altered Enzyme Activity ⬇️

scientific article published on October 1, 2012

Two-dimensional liquid chromatography-ion trap mass spectrometry for the simultaneous determination of ketorolac enantiomers and paracetamol in human plasma: application to a pharmacokinetic study

scientific article published on 3 March 2009

Uptake/efflux transport of tramadol enantiomers and O-desmethyl-tramadol: focus on P-glycoprotein

scientific article

Usefulness of PBPK Modeling in Incorporation of Clinical Conditions in Personalized Medicine

scientific article published on 26 April 2017

Validation of the Simplified UVB Model to Assess the Pharmacodynamics of Analgesics in Healthy Human Volunteers ⬇️

scientific article published on 01 January 2012

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