List of works by Dick Tibboel

"Out of the blue"-safety and efficacy of pulmonary hypertension treatment in childhood*.

scientific article published in May 2014

5q11.2 deletion in a patient with tracheal agenesis

scientific article published on 16 June 2010

A Comparative Analysis of Preemptive Versus Targeted Sedation on Cardiovascular Stability After High-Risk Cardiac Surgery in Infants

scientific article

A Comprehensive Analysis of Ontogeny of Renal Drug Transporters: mRNA Analyses, Quantitative Proteomics, and Localization

scientific article published on 03 July 2019

A Genetics-First Approach Revealed Monogenic Disorders in Patients With ARM and VACTERL Anomalies

scientific article published on 23 June 2020

A Systematic Review of Neuromonitoring Modalities in Children Beyond Neonatal Period After Cardiac Arrest

scientific article published on 11 June 2020

A baby with meningococcemia and septic shock

scientific article published on 11 June 2012

A bodyweight-dependent allometric exponent for scaling clearance across the human life-span.

scientific article

A clinical prediction rule for the severity of congenital diaphragmatic hernias in newborns

scientific article

A comparison in adolescents of composite auditory evoked potential index and bispectral index during propofol-remifentanil anesthesia for scoliosis surgery with intraoperative wake-up test

scientific article

A lack of intestinal pacemaker (c-kit) in aganglionic bowel of patients with Hirschsprung's disease

scientific article published on 01 March 1995

A novel maturation function for clearance of the cytochrome P450 3A substrate midazolam from preterm neonates to adults

scientific article

A novel method to determine small intestinal barrier function in human neonates in vivo

scientific article published on September 2006

A parent-reported standardised checklist is not sensitive to screen for motor problems at school age following neonatal critical illness

scientific article published on 28 January 2020

A population-based nested case control study on recurrent pneumonias in children with severe generalized cerebral palsy: ethical considerations of the design and representativeness of the study sample

scientific article

A prospective comparative evaluation of persistent respiratory morbidity in esophageal atresia and congenital diaphragmatic hernia survivors

scientific article published in September 2009

A randomized controlled trial of daily sedation interruption in critically ill children.

scientific article published on 24 November 2015

A survey of the use of off-label and unlicensed drugs in a Dutch children's hospital

scientific article published on 01 November 2001

A systematic review and narrative synthesis on the histological and neurobehavioral long-term effects of dexmedetomidine

scientific article published on 15 January 2019

ACTG2 variants impair actin polymerization in sporadic Megacystis Microcolon Intestinal Hypoperistalsis Syndrome.

scientific article

Aberrant SOX2 expression in colorectal cancers does not correlate with mucinous differentiation and gastric mucin MUC5AC expression.

scientific article published on 10 August 2014

Acetaminophen in cerebrospinal fluid in children

scientific article published on 4 July 2003

Achieving energy goals at day 4 after admission in critically ill children; predictive for outcome?

scientific article published on 11 February 2014

Actual body weight-based vancomycin dosing in neonates

scientific article published on 14 April 2019

Actual outcome in infants with congenital diaphragmatic hernia: the role of a standardized postnatal treatment protocol

scientific article published on 03 February 2011

Acute kidney injury is a frequent complication in critically ill neonates receiving extracorporeal membrane oxygenation: a 14-year cohort study

scientific article

Acute liver failure after recommended doses of acetaminophen in patients with myopathies

scientific article published on April 2011

Adequate feeding and the usefulness of the respiratory quotient in critically ill children

scientific article

Adherence to All Steps of a Pain Management Protocol in Intensive Care Patients after Cardiac Surgery Is Hard to Achieve

scientific article published on 16 February 2017

Adult spinal opioid receptor μ1 expression after incision is altered by early life repetitive tactile and noxious procedures in rats.

scientific article published on 22 February 2018

Advanced cancer pain: the search for genetic factors correlated with interindividual variability in opioid requirement

scientific article published on 26 July 2017

Adverse events of haloperidol for the treatment of delirium in critically ill children

scientific article published on 3 September 2014

Agenesis of the trachea: phenotypic expression of a rare cause of fatal neonatal respiratory insufficiency in six patients

scientific article published on 25 August 2005

Aggressive Surgical Management of Congenital Diaphragmatic Hernia: Worth the Effort?: A Multicenter, Prospective, Cohort Study

scientific article published on 27 January 2017

Allometric Scaling of Clearance in Paediatric Patients: When Does the Magic of 0.75 Fade?

scientific article published on 10 August 2016

Alternative Splicing of the SLCO1B1 Gene: An Exploratory Analysis of Isoform Diversity in Pediatric Liver

scientific article published on 09 January 2020

Alveolar capillary dysplasia with misalignment of the pulmonary veins: clinical, histological, and genetic aspects

Alveolar capillary dysplasia: a logical approach to a fatal disease

scientific article

Aminotransferase levels in relation to short-term use of acetaminophen four grams daily in postoperative cardiothoracic patients in the intensive care unit.

scientific article published in November 2011

Amnio-allantoic fluid exchange for the prevention of intestinal damage in gastroschisis: an experimental study on chick embryos

scientific article published on 01 March 1995

An exploratory study with an adaptive continuous intravenous furosemide regimen in neonates treated with extracorporeal membrane oxygenation

scientific article published on January 2007

An international survey of management of pain and sedation after paediatric cardiac surgery

scientific article published on 05 July 2017

Anaesthesia and postoperative analgesia in surgical neonates with or without Down's syndrome: is it really different?

scientific article published on 26 December 2011

Analgesia and Opioids: A Pharmacogenetics Shortlist for Implementation in Clinical Practice

scientific article published on 21 June 2017

Analgesia-sedation in PICU and neurological outcome: a secondary analysis of long-term neuropsychological follow-up in meningococcal septic shock survivors*.

scientific article published in March 2014

Analgesics and Sedatives in Critically Ill Newborns and Infants: The Impact on Long-Term Neurodevelopment

scientific article published on 01 October 2018

Analgosedation in PICUs: One Size Fits All or Beyond

scientific article published in September 2016

Analgosedation in paediatric severe traumatic brain injury (TBI): practice, pitfalls and possibilities.

scientific article published on 6 September 2017

Anatomical changes in descending serotonergic projections from the rostral ventromedial medulla to the spinal dorsal horn following repetitive neonatal painful procedures

scientific article published in 2022

Anesthesia and analgesia during and after surgery in neonates.

scientific article

Angiogenic factors stimulate tubular branching morphogenesis of sonic hedgehog-deficient lungs

scientific journal article

Antenatal therapy with sildenafil: don't throw the baby out with the bathwater

scientific article published on 01 February 2019

Are postoperative pain instruments useful for specific groups of vulnerable infants?

scientific article

Are we allowed to discontinue medical treatment in this child?

scientific article published on 2 February 2015

Arterial lactate for predicting mortality in children requiring extracorporeal membrane oxygenation

scientific article published on 10 April 2014

Assessing health-related quality-of-life changes in informal caregivers: an evaluation in parents of children with major congenital anomalies

scientific article

Assessing the Microcirculation With Handheld Vital Microscopy in Critically Ill Neonates and Children: Evolution of the Technique and Its Potential for Critical Care

scientific article published on 09 July 2019

Assessment and significance of long-term outcomes in pediatric surgery

scientific article published on 9 September 2017

Assessment of pain: can caregivers or relatives rate pain in nursing home residents?

scientific article published on 08 July 2009

Assessment of sedation levels in pediatric intensive care patients can be improved by using the COMFORT "behavior" scale

scientific article published on 01 January 2005

Association of congenital diaphragmatic hernia with limb-reduction defects

scientific article published on August 2003

Augmented Renal Clearance in Critically Ill Pediatric Patients: Does It Impact the Outcome of Pharmacotherapy?

scientific article published in September 2017

Avoidance of emergency surgery in newborn infants with trisomy 18

scientific article published on April 11, 1992

Awareness in children: another two cases

scientific article published on 8 May 2008

B-type natriuretic peptide as a parameter for pulmonary hypertension in children. A systematic review.

scientific article published on 23 August 2015

Big data analyses for continuous evaluation of pharmacotherapy: A proof of principle with doxapram in preterm infants

scientific article published on 18 September 2017

Biomarkers and clinical tools in critically ill children: are we heading toward tailored drug therapy?

scientific article published on June 2012

Biomarkers for paediatric traumatic brain injury

scientific article published on 21 June 2019

Biomarkers of the one-carbon pathway in association with congenital diaphragmatic hernia

scientific article published on 22 June 2012

Bispectral Index Monitoring in Terminally Ill Patients: A Validation Study

scientific article published on 21 May 2016

Brain connectivity during verbal working memory in children and adolescents

scientific article published on 11 December 2012

Brain injury associated with neonatal extracorporeal membrane oxygenation in the Netherlands: a nationwide evaluation spanning two decades

scientific article published in November 2013

CKD and hypertension during long-term follow-up in children and adolescents previously treated with extracorporeal membrane oxygenation.

scientific article

CLMP is required for intestinal development, and loss-of-function mutations cause congenital short-bowel syndrome

scientific article

CLONIDINE INDUCED BRADYCARDIA AND HYPOTENSION ARE FREQUENT IN CRITICALLY ILL CHILDREN, BUT DO NOT APPEAR TO COMPROMISE HEMODYNAMICS.

scientific article

Can Population Modelling Principles be Used to Identify Key PBPK Parameters for Paediatric Clearance Predictions? An Innovative Application of Optimal Design Theory

scholarly article by Elisa A M Calvier et al published 14 September 2018 in Pharmaceutical Research

Can we improve outcome of congenital diaphragmatic hernia?

scientific article published on September 2009

Cardiac Arrest in Children: Long-Term Health Status and Health-Related Quality of Life

scientific article

Cardiac arrest in infants, children, and adolescents: long-term emotional and behavioral functioning

scientific article published on 14 May 2016

Cardiovascular catecholamine receptors in children: their significance in cardiac disease

scientific article published on July 2011

Causes and consequences of inadequate substrate supply to pediatric ICU patients

scientific article

Cerebellar Growth Impairment Characterizes School-Aged Children Born Preterm without Perinatal Brain Lesions.

scientific article published on 22 March 2018

Cerebrospinal fluid pharmacokinetics of paracetamol after intravenous propacetamol in a former preterm infant

scientific article published on February 2004

Cervical ribs and other abnormalities of the vertebral pattern in children with esophageal atresia and anorectal malformations

scientific article published on 23 October 2019

Challenges and Pitfalls: Performing Clinical Trials in Patients With Congenital Diaphragmatic Hernia

scientific article published in 2022

Changes in HNK-1 distribution during neural crest cell culture

scientific article published in 1989

Changes in buccal microcirculation following extracorporeal membrane oxygenation in term neonates with severe respiratory failure

scientific article published in March 2009

Changes in thyroid hormone concentrations during neonatal extracorporeal membrane oxygenation.

scientific article published on 27 April 2017

Changes in vasoactive pathways in congenital diaphragmatic hernia associated pulmonary hypertension explain unresponsiveness to pharmacotherapy

scientific article published on 7 November 2017

Changing perspectives on the perinatal management of isolated congenital diaphragmatic hernia in Europe.

scientific article published on June 2009

Characteristics of Infants With Congenital Diaphragmatic Hernia Who Need Follow-Up of Pulmonary Hypertension

scientific article

Characterization of HNK-1 antigens during the formation of the avian enteric nervous system

scientific article published on June 1, 1992

Characterization of iodothyronine sulfatase activities in human and rat liver and placenta

scientific article published in March 2002

Characterization of rat iodothyronine sulfotransferases

scientific article published on 28 May 2003

Children and accidents: decreasing mortality, different care

scientific article published on 01 September 1990

Children in clinical trials: towards evidence-based pediatric pharmacotherapy using pharmacokinetic-pharmacodynamic modeling.

scientific article

Children with intellectual disabilities and pain perception: a review and suggestions for future assessment protocols.

scientific article published on June 2009

Children's outcomes at 2-year follow-up after 4 years of structured multi-professional medical-ethical decision-making in a neonatal intensive care unit

scientific article published on 30 March 2017

Chromosomal anomalies in the aetiology of oesophageal atresia and tracheo-oesophageal fistula

scientific article published on 21 January 2007

Clinical and etiological heterogeneity in patients with tracheo-esophageal malformations and associated anomalies.

scientific article

Clinical geneticists' views of VACTERL/VATER association

scientific article published on 19 November 2012

Clinical practice: analgesia in neonates.

scientific article published on 17 February 2009

Clinical recommendations for pain, sedation, withdrawal and delirium assessment in critically ill infants and children: an ESPNIC position statement for healthcare professionals

scientific article

Clinical relevancy of nonurinary nitrogen excretion in newborns and infants after digestive tract surgery.

scientific article published in September 2003

Clinically effective implementation of intravenous paracetamol as primary analgesia after major surgery in neonates and young infants

scientific article published on 10 July 2018

Clinically relevant timing of antenatal sildenafil treatment reduces pulmonary vascular remodeling in congenital diaphragmatic hernia

scientific article published on 12 August 2016

Clonidine as a First-Line Sedative Agent After Neonatal Cardiac Surgery: Retrospective Cohort Study.

scientific article published on 24 February 2016

Coagulation complications after conversion from roller to centrifugal pump in neonatal and pediatric extracorporeal membrane oxygenation

scientific article published on 25 November 2020

Cohort Profile: The Rotterdam Periconceptional Cohort (Predict Study)

scientific article published on 29 July 2015

Colonization characteristics of enteric neural crest cells: embryological aspects of Hirschsprung's disease

scientific article published on 01 July 1992

Combining Brain Microdialysis and Translational Pharmacokinetic Modeling to Predict Drug Concentrations in Pediatric Severe Traumatic Brain Injury: The Next Step Toward Evidence-Based Pharmacotherapy?

scientific article published on 06 September 2018

Comparable low-level mosaicism in affected and non affected tissue of a complex CDH patient

scientific article

Comparison of bispectral index and composite auditory evoked potential index for monitoring depth of hypnosis in children

scientific article published in May 2008

Comparison of different pain scoring systems in critically ill patients in a general ICU.

scientific article published on 16 February 2008

Congenital Diaphragmatic Hernia and Growth to 12 Years

scientific article published on 14 July 2017

Congenital Diaphragmatic Hernia: 10-Year Evaluation of Survival, Extracorporeal Membrane Oxygenation, and Foetoscopic Endotracheal Occlusion in Four High-Volume Centres

scientific article published on 28 October 2017

Congenital diaphragmatic hernia

Congenital diaphragmatic hernia

scientific article published on 31 October 2012

Congenital diaphragmatic hernia and a complex heart defect in association with Wolf–Hirschhorn syndrome

scientific article published on 01 November 2010

Congenital diaphragmatic hernia and exercise capacity, a longitudinal evaluation

scientific article published on 11 February 2019

Congenital diaphragmatic hernia and situs inversus totalis

scientific article published in March 2004

Congenital diaphragmatic hernia in a female patient with craniofrontonasal syndrome

scientific article published on 01 April 2002

Congenital diaphragmatic hernia in a patient with tetrasomy 9p.

scientific article published in October 2005

Congenital diaphragmatic hernia with(out) ECMO: impaired development at 8 years

scientific article published on 12 December 2012

Congenital diaphragmatic hernia: comparison of animal models and relevance to the human situation.

scientific article published on 27 March 2009

Congenital diaphragmatic hernia: impact of preoperative stabilization. A prospective pilot study in 13 patients

scientific article published on 01 December 1988

Congenital diaphragmatic hernia: long-term risk of gastroesophageal reflux disease.

scientific article published on October 2010

Congenital diaphragmatic hernia: still a moving target

scientific article published on 03 April 2011

Congenital diaphragmatic hernia: to repair on or off extracorporeal membrane oxygenation?

scientific article published in April 2012

Congenital pulmonary airway malformation: advances and controversies

scientific article published on 17 February 2018

Construction of the Sophia Observation withdrawal Symptoms-scale (SOS) for critically ill children

scientific article

Continuous Intravenous Acetaminophen for Analgesia: First, Back to the Drawing Table?

scientific article published on 24 July 2017

Continuous noninvasive monitoring of barbiturate coma in critically ill children using the Bispectral index monitor.

scientific article published on January 2007

Contribution of LPP copy number and sequence changes to esophageal atresia, tracheoesophageal fistula, and VACTERL association

scientific article published on 25 May 2012

Contribution of glucuronidation to tramadol disposition in early neonatal life.

scientific article published in January 2006

Conventional Mechanical Ventilation Versus High-frequency Oscillatory Ventilation for Congenital Diaphragmatic Hernia: A Randomized Clinical Trial (The VICI-trial).

scientific article published on 16 December 2015

Copy number detection in discordant monozygotic twins of Congenital Diaphragmatic Hernia (CDH) and Esophageal Atresia (EA) cohorts

scientific article published on 9 November 2011

Copy number variations in 375 patients with oesophageal atresia and/or tracheoesophageal fistula

scientific article

Correction to: Gabapentin as add-on to morphine for severe neuropathic or mixed pain in children from age 3 months to 18 years - evaluation of the safety, pharmacokinetics, and efficacy of a new gabapentin liquid formulation: study protocol for a ra

scientific article published on 20 June 2019

Corrigendum: Assessing the Microcirculation With Handheld Vital Microscopy in Critically lll Neonates and Children: Evolution of the Technique and Its Potential for Critical Care

scientific article published on 21 August 2019

Cost-effectiveness of neonatal surgery: first greeted with scepticism, now increasingly accepted.

scientific article published on 6 November 2007

Covariates of tramadol disposition in the first months of life.

scientific article

Creating or preventing opioid addiction, finding the right dose

scientific article published in September 2011

Critical illness is a major determinant of midazolam clearance in children aged 1 month to 17 years

scientific article

Cutaneous microcirculation in preterm neonates: comparison between sidestream dark field (SDF) and incident dark field (IDF) imaging.

scientific article published on 29 May 2015

Daily interruption of sedation in critically ill children

scientific article published on 01 January 2012

Daily interruption of sedation in critically ill children: study protocol for a randomized controlled trial.

scientific article published on 13 February 2014

Decreased surfactant phosphatidylcholine synthesis in neonates with congenital diaphragmatic hernia during extracorporeal membrane oxygenation.

scientific article published on 07 July 2009

Defect size determines survival in infants with congenital diaphragmatic hernia

scientific article

Deficiency of FRAS1-related extracellular matrix 1 (FREM1) causes congenital diaphragmatic hernia in humans and mice

scientific article published on 04 February 2020

Deficiency of FRAS1-related extracellular matrix 1 (FREM1) causes congenital diaphragmatic hernia in humans and mice.

scientific article published on 5 December 2012

Defining outcomes following congenital diaphragmatic hernia using standardised clinical assessment and management plan (SCAMP) methodology within the CDH EURO consortium

scientific article published on 29 May 2018

Delivering transformative action in paediatric pain: a Lancet Child & Adolescent Health Commission

scientific article published on 12 October 2020

Deterioration of exercise capacity after neonatal extracorporeal membrane oxygenation

scientific article published on 3 May 2011

Determinants of drug absorption in different ECMO circuits.

scientific article published on 23 September 2010

Determinants of exercise capacity in school-aged esophageal atresia patients

scientific article

Development of Human Membrane Transporters: Drug Disposition and Pharmacogenetics

scientific article

Developmental and genetic aspects of congenital diaphragmatic hernia

scientific article published on 29 March 2012

Developmental changes in morphine clearance across the entire paediatric age range are best described by a bodyweight-dependent exponent model.

scientific article published in July 2013

Developmental changes rather than repeated administration drive paracetamol glucuronidation in neonates and infants.

scientific article

Developmental fluoxetine exposure normalizes the long-term effects of maternal stress on post-operative pain in Sprague-Dawley rat offspring

scientific article

Developmental neurobiology as a guide for pharmacological management of pain in neonates

scientific article published on 10 May 2019

Developmental pharmacokinetics of morphine and its metabolites in neonates, infants and young children.

scientific article

Developmental pharmacokinetics of opioids in neonates.

scientific article published on January 2007

Developmental problems in patients with oesophageal atresia: a longitudinal follow-up study

scientific article published on 31 August 2016

Diagnosis and Treatment of Chronic Neuropathic and Mixed Pain in Children and Adolescents: Results of a Survey Study amongst Practitioners

scientific article published on 02 November 2020

Diagnosis-related deterioration of lung function after extracorporeal membrane oxygenation

scientific article published on 10 April 2012

Diclofenac and metabolite pharmacokinetics in children

scientific article

Diclofenac pharmacokinetic meta-analysis and dose recommendations for surgical pain in children aged 1-12 years

scientific article published on 30 January 2011

Dietary protein absorption of the small intestine in human neonates

scientific article published in November 2007

Dietary vitamin A intake below the recommended daily intake during pregnancy and the risk of congenital diaphragmatic hernia in the offspring

scientific article published on 2 January 2013

Differences in phosphorylation state of neurofilament proteins in ganglionic and aganglionic bowel segments of children with Hirschsprung's disease

scientific article published on 01 July 1992

Differentiated type II pneumocytes can be reprogrammed by ectopic Sox2 expression

scientific article (publication date: 2014)

Discomfort and pain in newborns with myelomeningocele: a prospective evaluation

scientific article published on 27 February 2012

Distal angiogenesis: a new concept for lung vascular morphogenesis

scientific article published on 17 September 2004

Disturbed balance between SOX2 and CDX2 in human vitelline duct anomalies and intestinal duplications

scientific article published on 09 April 2013

Do we still hurt newborn babies? A prospective study of procedural pain and analgesia in neonates

scientific article published in November 2003

Does V-A ECMO increase the likelihood of chylothorax after congenital diaphragmatic hernia repair?

scientific article published in June 2003

Does minimal access major surgery in the newborn hurt less? An evaluation of cumulative opioid doses

scientific article published on 30 December 2010

Does neonatal morphine use affect neuropsychological outcomes at 8 to 9 years of age?

scientific article published on 20 December 2012

Does neonatal surgery lead to increased pain sensitivity in later childhood?

scientific article

Does pharmacotherapy influence the inflammatory responses during cardiopulmonary bypass in children?

scientific article

Does postoperative 'M' technique massage with or without mandarin oil reduce infants' distress after major craniofacial surgery?

scientific article

Does small intestinal atresia affect epithelial protein expression in human newborns?

scientific article published in November 2006

Dose-linearity of the pharmacokinetics of an intravenous [14 C]midazolam microdose in children

scientific article published on 30 July 2019

Down-regulation of sonic hedgehog expression in pulmonary hypoplasia is associated with congenital diaphragmatic hernia

scientific article published on February 2003

Drug Disposition and Pharmacotherapy in Neonatal ECMO: From Fragmented Data to Integrated Knowledge

scientific article published on 03 September 2019

Drug metabolism for the paediatrician

scientific article published on 03 September 2014

Drug metabolism in early infancy: opioids as an illustration

scientific article published on 24 January 2018

Drugs Being Eliminated via the Same Pathway Will Not Always Require Similar Pediatric Dose Adjustments

scientific article published on 5 February 2018

Dual-hit hypothesis explains pulmonary hypoplasia in the nitrofen model of congenital diaphragmatic hernia

scientific article

Dysphagia in children with severe generalized cerebral palsy and intellectual disability

scientific article published on 01 August 2008

Early developmental assessment of children with major non-cardiac congenital anomalies predicts development at the age of 5 years.

scientific article published on 24 September 2010

Early management in children with burns: Cooling, wound care and pain management.

scientific article

Early microcirculatory impairment during therapeutic hypothermia is associated with poor outcome in post-cardiac arrest children: a prospective observational cohort study

scientific article

Early versus Late Parenteral Nutrition in Critically Ill Children

scientific article published on 15 March 2016

Effect of Artificial Ventilation on Pulmonary Antioxidant Enzyme Activities in a Congenital Diaphragmatic Hernia Rat Model

scientific article published on 01 January 1992

Effect of UGT2B7 -900G>A (-842G>A; rs7438135) on morphine glucuronidation in preterm newborns: results from a pilot cohort.

scientific article

Effect of chemical stabilizers of hypoxia-inducible factors on early lung development

article

Effect of enteral IGF-1 supplementation on feeding tolerance, growth, and gut permeability in enterally fed premature neonates

scientific article published in February 2008

Effect of hypothermia and extracorporeal life support on drug disposition in neonates

scientific article

Effect of intravenous paracetamol on postoperative morphine requirements in neonates and infants undergoing major noncardiac surgery: a randomized controlled trial

scientific article published on January 2013

Effect of maternal administration of betamethasone on peripheral arterial development in fetal rabbit lungs

scientific article published on 16 August 2007

Effect of oxygen on the expression of hypoxia-inducible factors in human fetal lung explants

scientific article published on 25 November 2009

Effects of betamethasone on peripheral arterial development in term fetal rabbit.

scientific article published in August 2008

Effects of low-dose naloxone on opioid therapy in pediatric patients: a retrospective case-control study

scientific article published on 7 November 2006

Effects of repetitive exposure to pain and morphine treatment on the neonatal rat brain

scientific article published on 3 October 2012

Efficacy and safety of a parenteral amino acid solution containing alanyl-glutamine versus standard solution in infants: a first-in-man randomized double-blind trial

scientific article published on 10 October 2012

Efficacy of antibody NF2F11 staining in the investigation of severe long-standing constipation. A preliminary report

scientific article published on 01 October 1987

Efficacy of continuous versus intermittent morphine administration after major surgery in 0-3-year-old infants; a double-blind randomized controlled trial

scientific article

Eight Years Later, Are We Still Hurting Newborn Infants?

article by Daniëlla W.E. Roofthooft et al published 2014 in Neonatology

Endpoints in pediatric pain studies

scientific article

Energy intake does not correlate with nutritional state in children with severe generalized cerebral palsy and intellectual disability.

scientific article published on 25 March 2010

Enteral Acetaminophen Bioavailability in Pediatric Intensive Care Patients Determined With an Oral Microtracer and Pharmacokinetic Modeling to Optimize Dosing

scientific article published on 01 December 2019

Enteral nutrition in children with short-bowel syndrome: current evidence and recommendations for the clinician

scientific article published on March 2010

Environmental factors in the etiology of esophageal atresia and congenital diaphragmatic hernia: results of a case-control study

scientific article published in February 2008

Epidemiology and Outcome of Critically Ill Pediatric Cancer and Hematopoietic Stem Cell Transplant Patients Requiring Continuous Renal Replacement Therapy: A Retrospective Nationwide Cohort Study

scientific article published on 01 November 2019

Epithelial functions of the residual bowel after surgery for necrotising enterocolitis in human infants.

scientific article

Esophageal atresia and tracheoesophageal fistula in children of women exposed to diethylstilbestrol in utero

scientific article published on 01 July 2007

Ethical aspects of care in the newborn surgical patient

scientific article published on 06 September 2014

Ethical aspects of clinical research with minors

scientific article published on 17 October 2012

Ethics of drug research in the pediatric intensive care unit

scientific article

Etiological and pathogenic factors in congenital diaphragmatic hernia.

scientific article published on 31 October 2012

Etiology of esophageal atresia and tracheoesophageal fistula: "mind the gap".

scientific article published on June 2010

Evaluation of drug formularies for pediatric intensive care

scientific article published on 01 January 2011

Evaluation of furosemide regimens in neonates treated with extracorporeal membrane oxygenation

scientific article published on January 2006

Evidence-based drug treatment for special patient populations through model-based approaches.

scientific article published on 11 May 2017

Evidence-based morphine dosing for postoperative neonates and infants

scientific article published in June 2014

Exclusion of aPAX6,FOXC1,PITX2, andMYCN mutation in another patient with apple peel intestinal atresia, ocular anomalies and microcephaly and review of the literature

article

Exercise capacity in Dutch children: new reference values for the Bruce treadmill protocol

scientific article

Exercise capacity, daily activity, and severity of fatigue in term born young adults after neonatal respiratory failure

scientific article published on 21 June 2012

Exercise testing of pre-school children using the Bruce treadmill protocol: new reference values

scientific article

Experimentally induced congenital diaphragmatic hernia in rats

scientific article published on 01 April 1990

Exploring copy number variants in deceased fetuses and neonates with abnormal vertebral patterns and cervical ribs

scientific article published on 04 August 2020

Exploring the Relationship Between Morphine Concentration and Oversedation in Children After Cardiac Surgery

scientific article published on 20 May 2020

Exportin 4 mediates a novel nuclear import pathway for Sox family transcription factors

scientific article published on April 2009

Exposure to acetaminophen and all its metabolites upon 10, 15, and 20 mg/kg intravenous acetaminophen in very-preterm infants.

scientific article published on 29 May 2017

Expression and function of phosphodiesterases in nitrofen-induced congenital diaphragmatic hernia in rats

scientific article published in April 2010

Expression of Hypoxia-Inducible Factors in Normal Human Lung Development

article

Expression of angiogenesis-related factors in lungs of patients with congenital diaphragmatic hernia and pulmonary hypoplasia of other causes

Expression of glucocorticoid, retinoid, and thyroid hormone receptors during human lung development

scientific article

Expression of hypoxia-inducible factors, regulators, and target genes in congenital diaphragmatic hernia patients.

scientific article published on 14 June 2011

Expression of thyroid hormone receptors A and B in developing rat tissues; evidence for extensive posttranscriptional regulation

scientific journal article

Extent of intestinal damage in the developing chick embryo after repetitive hypoxia under normoxic or hyperoxic conditions

scientific article published on 01 May 2001

Fast detection of FOXF1 variants in patients with alveolar capillary dysplasia with misalignment of pulmonary veins using targeted sequencing

scientific article published on 15 May 2020

Feasibility of bioelectrical impedance analysis in children with a severe generalized cerebral palsy

scientific article published in January 2006

Feasibility of sedation and analgesia interruption following cannulation in neonates on extracorporeal membrane oxygenation

scientific article

Fetal lung and diaphragm development in congenital diaphragmatic hernia

scientific article

Five-year follow-up of effects of neonatal intensive care and morphine infusion during mechanical ventilation on diurnal cortisol rhythm

scientific article published in July 2014

Follow-up of newborns treated with extracorporeal membrane oxygenation: a nationwide evaluation at 5 years of age.

scientific article published on January 2006

From Pediatric Covariate Model to Semiphysiological Function for Maturation: Part II-Sensitivity to Physiological and Physicochemical Properties

scientific article published on 10 October 2012

From pediatric covariate model to semiphysiological function for maturation: part I-extrapolation of a covariate model from morphine to Zidovudine

scientific article published on 3 October 2012

Functional Capillary Density Decreases after the First Week of Life in Term Neonates

scientific article published on August 24, 2010

Functional MRI pain studies in children? Yes, we (s)can!

Gabapentin as add-on to morphine for severe neuropathic or mixed pain in children from age 3 months to 18 years - evaluation of the safety, pharmacokinetics, and efficacy of a new gabapentin liquid formulation: study protocol for a randomized con

Gastrointestinal hormone secretion after surgery in neonates with congenital intestinal anomalies during starvation and introduction of enteral nutrition

scientific article published on November 1, 2003

Gastroschisis at school age: what do parents report?

scientific article published on 19 July 2019

Generation of a biotinylatable Sox2 mouse model to identify Sox2 complexes in vivo.

scientific article published on 30 January 2018

Genetic and environmental factors in the etiology of esophageal atresia and/or tracheoesophageal fistula: an overview of the current concepts

scientific article published on September 2009

Genetic factors in congenital diaphragmatic hernia

scientific article published on 4 April 2007

Genetic variants associated with thermal pain sensitivity in a paediatric population.

scientific article published on 14 July 2016

Genetics

scientific article published on 01 August 2010

Genetics and developmental biology of oesophageal atresia and tracheo-oesophageal fistula: lessons from mice relevant for paediatric surgeons.

scientific article

Genome wide DNA methylation analysis of alveolar capillary dysplasia lung tissue reveals aberrant methylation of genes involved in development including the FOXF1 locus

scientific article published on 29 July 2021

Genome-wide oligonucleotide-based array comparative genome hybridization analysis of non-isolated congenital diaphragmatic hernia

scientific article published on 08 January 2007

Genomic alterations that contribute to the development of isolated and non-isolated congenital diaphragmatic hernia

scientific article published on May 2011

Ghrelin expression in human and rat fetal lungs and the effect of ghrelin administration in nitrofen-induced congenital diaphragmatic hernia

scientific article

Glutamine supplementation of parenteral nutrition does not improve intestinal permeability, nitrogen balance, or outcome in newborns and infants undergoing digestive-tract surgery: results from a double-blind, randomized, controlled trial

scientific article published in April 2005

Growing Up After Critical Illness: Verbal, Visual-Spatial, and Working Memory Problems in Neonatal Extracorporeal Membrane Oxygenation Survivors.

scientific article

Growth and development after oesophageal atresia surgery: Need for long-term multidisciplinary follow-up

scientific article published on 23 July 2015

Growth and nutritional aspects of infantile short bowel syndrome for the past 2 decades

scientific article published in November 2008

Gut hormone profiles in critically ill neonates on extracorporeal membrane oxygenation

scientific article published on 01 February 2005

Gut hormones in preterm infants with necrotizing enterocolitis during starvation and reintroduction of enteral nutrition

scientific article published on 01 November 2002

HORMONE LEVELS IN CHILDREN DURING THE FIRST WEEK OF ICU-ADMISSION: IS THERE AN EFFECT OF ADEQUATE FEEDING?

scientific article published in 2005

Haemofiltration in newborns treated with extracorporeal membrane oxygenation: a case-comparison study

scientific article published on 03 April 2009

Hemodynamic Tolerance to IV Clonidine Infusion in the PICU

scientific article published on 01 August 2018

Hemodynamic coherence in critically ill pediatric patients

scientific article published on 31 October 2016

High cumulative oxygen levels are associated with improved survival of children treated with mild therapeutic hypothermia after cardiac arrest.

scientific article

High-Sensitivity Troponin T and N-Terminal Pro-Brain Natriuretic Peptide in Prediction of Outcome in Congenital Diaphragmatic Hernia: Results from a Multicenter, Randomized Controlled Trial

scientific article

Hirschsprung's disease studied with monoclonal antineurofilament antibodies on tissue sections

scientific article published on March 24, 1984

Histological, immunohistochemical and transcriptomic characterization of human tracheoesophageal fistulas

scientific article published on 17 November 2020

Homozygous nonsense mutations in KIAA1279 are associated with malformations of the central and enteric nervous systems

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Hormone levels in children during the first week of ICU-admission: is there an effect of adequate feeding?

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How often do we perform painful and stressful procedures in the paediatric intensive care unit? A prospective observational study

How to achieve adherence to a ventilation algorithm for critically ill children?

scientific article published in October 2014

Human Intestinal PEPT1 Transporter Expression and Localization in Preterm and Term Infants

scientific article published on 14 April 2016

Hyperoxia in pediatric severe traumatic brain injury (TBI): a comparison of patient classification by cutoff versus cumulative (area-under-the-curve) analysis

scientific article published on 02 June 2020

Hypoalbuminaemia and decreased midazolam clearance in terminally ill adult patients, an inflammatory effect?

scientific article

Hypoxia inducible factor 2α (HIF2α/EPAS1) is associated with development of pulmonary hypertension in severe congenital diaphragmatic hernia patients.

scientific article published in June 2018

Hypoxia inducible factor 3α plays a critical role in alveolarization and distal epithelial cell differentiation during mouse lung development

scientific article

Hypoxia-Inducible Factor 2α Plays a Critical Role in the Formation of Alveoli and Surfactant

article

Hypoxia-Inducible Factor-1 Stimulates Postnatal Lung Development but Does Not Prevent O2-Induced Alveolar Injury

article

Hypoxia-inducible factors in the first trimester human lung.

scientific article published on 22 December 2006

Illness severity and parental permission for clinical research in a pediatric ICU population

scientific article published on 13 May 2005

Impact of a child with congenital anomalies on parents (ICCAP) questionnaire; a psychometric analysis

scientific article

Impact of enantiomer-specific changes in pharmacokinetics between infants and adults on the target concentration of racemic ketorolac- a pooled analysis

scientific article published on 09 September 2020

Impact of haemolysis on vancomycin disposition in a full-term neonate treated with extracorporeal membrane oxygenation

scientific article published on 17 November 2020

Impact of infantile short bowel syndrome on long-term health-related quality of life: a cross-sectional study

scientific article published in July 2012

Impact of withholding early parenteral nutrition completing enteral nutrition in pediatric critically ill patients (PEPaNIC trial): study protocol for a randomized controlled trial

scientific article published on May 2015

Impaired Neurodevelopmental Outcomes in Very Preterm Infants: Much Too Easy to Blame It Just on Morphine!

scientific article published on 16 February 2016

Implementation of a children's hospital-wide central venous catheter insertion and maintenance bundle

scientific article

Implementation of a nurse-driven ventilation weaning protocol in critically ill children: Can it improve patient outcome?

scientific article published on 13 March 2019

Implementation of standard sedation management in paediatric intensive care: effective and feasible?

scientific article published on 8 July 2009

Improvement of exercise capacity following neonatal respiratory failure: A randomized controlled trial

scientific article published on 15 December 2019

Improving Long-Term Outcomes After Extracorporeal Membrane Oxygenation: From Observational Follow-Up Programs Toward Risk Stratification.

scientific article published on 26 June 2018

In Vitro Adsorption of Analgosedative Drugs in New Extracorporeal Membrane Oxygenation Circuits

scientific article published on 6 February 2018

In Vitro Recovery of Sufentanil, Midazolam, Propofol, and Methylprednisolone in Pediatric Cardiopulmonary Bypass Systems

scientific article published on 29 August 2019

Increasing mean arterial blood pressure and heart rate with catecholaminergic drugs does not improve the microcirculation in children with congenital diaphragmatic hernia: a prospective cohort study

scientific article published in May 2014

Infantile hypertrophic pyloric stenosis in patients with esophageal atresia

scientific article published on 16 April 2020

Infants Operated on for Necrotizing Enterocolitis: Towards Evidence-Based Pain Guidelines

scientific article published on 20 May 2016

Inflammation and Organ Failure Severely Affect Midazolam Clearance in Critically Ill Children

scientific article

Inhaled nitric oxide improves systemic microcirculation in infants with hypoxemic respiratory failure

scientific article published in November 2011

Inhibition of T3-receptor binding by Nitrofen.

scientific article

Inhibition of retinoic acid signaling induces aberrant pericyte coverage and differentiation resulting in vascular defects in congenital diaphragmatic hernia

scientific article published on 03 July 2019

Innovative approaches and recent advances in the study of ontogeny of drug metabolism and transport

scientific article published on 26 August 2020

Integration of Placental Transfer in a Fetal-Maternal Physiologically Based Pharmacokinetic Model to Characterize Acetaminophen Exposure and Metabolic Clearance in the Fetus

scientific article published on 12 February 2020

Interdisciplinary management of infantile short bowel syndrome: resource consumption, growth, and nutrition

scientific article

Interdisciplinary structural follow-up of surgical newborns: a prospective evaluation

scientific article published on July 2009

Interstitial 11q deletion derived from a maternal ins(4;11)(p14;q24.2q25): a patient report and review

scientific article published on 01 July 2009

Intestinal atresia and stenosis in animals: a report of 34 cases

scientific article published on 01 September 1980

Intra- and interindividual variability of glucuronidation of paracetamol during repeated administration of propacetamol in neonates

scientific article published in September 2005

Intraoperative awareness during paediatric anaesthesia

scientific article published on 5 November 2008

Intrauterine exposure to indomethacin

scientific article published on 01 December 1986

Intravenous morphine versus intravenous paracetamol after cardiac surgery in neonates and infants: a study protocol for a randomized controlled trial.

scientific article published on 13 June 2018

Intravenous or Oral Acetaminophen for Analgesia After Cesarean Section: Exposure Drives Pain Relief

scientific article published on 01 November 2019

Intravenous paracetamol (propacetamol) pharmacokinetics in term and preterm neonates

scientific article published on 8 April 2004

Intravenous paracetamol dosing guidelines for pain management in (pre)term neonates using the paediatric study decision tree.

scientific article published on 21 September 2017

Invasive ventilation modes in children: a systematic review and meta-analysis

scientific article published on 17 January 2011

Iroquois genes influence proximo-distal morphogenesis during rat lung development

scientific article published on 18 November 2005

Is Intraoperative Remifentanil Associated With Acute or Chronic Postoperative Pain After Prolonged Surgery? An Update of the Literature

scientific article

Is pain assessment feasible as a performance indicator for Dutch nursing homes? A cross-sectional approach

scientific article published on 24 July 2010

Is the Glass Half Full or Half Empty?

scientific article published on 15 December 2015

Is the temporal artery thermometer a reliable instrument for detecting fever in children?

scientific article published on 22 March 2011

Isolated or non-isolated duodenal obstruction: perinatal outcome following prenatal or postnatal diagnosis

scientific article published in November 2008

Large differences in neonatal drug use between NICUs are common practice: time for consensus?

scientific article

Late vs early ostomy closure for necrotizing enterocolitis: analysis of adhesion formation, resource consumption, and costs

scientific article

Light at the Horizon? Predicting Mortality in Infants With Congenital Diaphragmatic Hernia

scientific article published on 01 June 2019

Limited effects of intravenous paracetamol on patent ductus arteriosus in very low birth weight infants with contraindications for ibuprofen or after ibuprofen failure

scientific article

Linking animal models to human congenital diaphragmatic hernia

scientific article published on August 2007

Liquid ventilation in congenital diaphragmatic hernia: back on stage?

scientific article published on 01 November 2014

Long-Term Effects of Neonatal Morphine Infusion on Pain Sensitivity: Follow-Up of a Randomized Controlled Trial

scientific article

Long-term effects of early exposure to stress, pain, opioids and anaesthetics on pain sensitivity and neurocognition

scientific article published on 26 September 2017

Long-term effects of routine morphine infusion in mechanically ventilated neonates on children's functioning: five-year follow-up of a randomized controlled trial.

scientific article published on 12 March 2011

Long-term impact of infantile short bowel syndrome on nutritional status and growth

scientific article

Long-term neuropsychological outcomes in children and adolescents after cardiac arrest

scientific article published on 18 April 2015

Loop diuretics are an independent risk factor for acute kidney injury in children on extracorporeal membrane oxygenation with pre-emptive continuous hemofiltration

scientific article published on 11 February 2014

Loss of LMOD1 impairs smooth muscle cytocontractility and causes megacystis microcolon intestinal hypoperistalsis syndrome in humans and mice.

scientific article

Loss-of-Function Variants in MYLK Cause Recessive Megacystis Microcolon Intestinal Hypoperistalsis Syndrome

scientific article published on 7 June 2017

Lower bispectral index values in children who are intellectually disabled.

scientific article published in November 2009

Lumbar spine and total-body dual-energy X-ray absorptiometry in children with severe neurological impairment and intellectual disability: a pilot study of artefacts and disrupting factors.

scientific article published on 18 January 2012

Lung function in school-aged congenital diaphragmatic hernia patients; a longitudinal evaluation

scientific article published on 13 June 2019

Lung function in young adults with congenital diaphragmatic hernia; a longitudinal evaluation

scientific article published on 26 March 2012

Lung function of infants with congenital lung lesions in the first year of life

scientific article published on 23 October 2012

Lung function, exercise tolerance, and physical growth of children with congenital lung malformations at 8 years of age

scientific article published on 22 April 2019

Lysyl oxidase activity is dysregulated during impaired alveolarization of mouse and human lungs

scientific article

Major surgery within the first 3 months of life and subsequent biobehavioral pain responses to immunization at later age: a case comparison study

scientific article

Male sex predisposes the newborn surgical patient to parenteral nutrition-associated cholestasis and to sepsis

scientific article published on 01 July 2002

Malnutrition in critically ill children: from admission to 6 months after discharge.

scientific article

Management of pulmonary hypertension in neonates with congenital diaphragmatic hernia

scientific article published on 31 October 2012

Maturational changes in the in vivo activity of CYP3A4 in the first months of life.

scientific article published in July 2006

Measuring body composition and energy expenditure in children with severe neurologic impairment and intellectual disability.

scientific article published on 27 July 2011

Measuring pain in children with cognitive impairment: pain response to surgical procedures

scientific article published on 01 May 2003

Medication use during end-of-life care in a palliative care centre

scientific article

Memory deficits following neonatal critical illness: a common neurodevelopmental pathway

scientific article published on 10 January 2018

Metabolic disturbances of the vitamin A pathway in human diaphragmatic hernia

scientific article

Methadone effectively attenuates acute and long-term consequences of neonatal repetitive procedural pain in a rat model

scientific article published in 2021

Microanalysis of beta-lactam antibiotics and vancomycin in plasma for pharmacokinetic studies in neonates

scientific article published on 27 October 2008

Minor painful procedures in the NICU: improved care or too soon for cheering?

scientific article published in July 2009

Mitochondrial Oxygen Monitoring During Surgical Repair of Congenital Diaphragmatic Hernia or Esophageal Atresia: A Feasibility Study

scientific article published on 02 September 2020

Model-based clinical dose optimization for phenobarbital in neonates: An illustration of the importance of data sharing and external validation.

scientific article

Models for infantile hypertrophic pyloric stenosis development in patients with esophageal atresia

Monitoring Haloperidol Plasma Concentration and Associated Adverse Events in Critically Ill Children With Delirium: First Results of a Clinical Protocol Aimed to Monitor Efficacy and Safety

scientific article published on 12 December 2017

More than fetal urine: enteral uptake of amniotic fluid as a major predictor for fetal growth during late gestation.

scientific article published on 16 March 2016

Morphine Glucuronidation and Elimination in Intensive Care Patients: A Comparison with Healthy Volunteers

scientific article

Morphine Pharmacodynamics in Mechanically Ventilated Preterm Neonates Undergoing Endotracheal Suctioning

scientific article published on 21 January 2017

Morphine glucuronidation in preterm neonates, infants and children younger than 3 years

scientific article

Morphine metabolite pharmacokinetics during venoarterial extra corporeal membrane oxygenation in neonates.

scientific article published in January 2006

Morphine pharmacokinetics during venoarterial extracorporeal membrane oxygenation in neonates.

scientific article

Morphine treatment for Neonatal Abstinence Syndrome: huge dosing variability underscores the need for a better clinical study design

scientific article published on 3 March 2017

Morphologic changes and methodological issues in the rabbit experimental model for diaphragmatic hernia

scientific article published on 01 September 2010

Morphometric analysis of the lung vasculature after extracorporeal membrane oxygenation treatment for pulmonary hypertension in newborns

scientific article published on 03 June 2004

Mortality in very long-stay pediatric intensive care unit patients and incidence of withdrawal of treatment

scientific article published on 24 October 2009

Motor performance after neonatal extracorporeal membrane oxygenation: a longitudinal evaluation

scientific article published on 01 August 2014

Motor performance in five-year-old extracorporeal membrane oxygenation survivors: a population-based study.

scientific article published on 02 April 2009

Motor-function and exercise capacity in children with major anatomical congenital anomalies: an evaluation at 5 years of age.

scientific article published in August 2010

Mouse model reveals the role of SOX7 in the development of congenital diaphragmatic hernia associated with recurrent deletions of 8p23.1.

scientific article

Multicenter Experience With Mechanical Circulatory Support Using a New Diagonal Pump in 233 Children.

scientific article

N-Terminal-pro-B Type Natriuretic Peptide as a Useful Tool to Evaluate Pulmonary Hypertension and Cardiac Function in CDH Infants

article by Maria João Baptista et al published 2008 in Neonatology

Narcotic-Sparing Approaches and the Shift Toward Paracetamol in Neonatal Intensive Care

scientific article published on 17 March 2019

Nationwide Evaluation of Congenital Hypothyroidism Screening during Neonatal Extracorporeal Membrane Oxygenation.

scientific article published on 17 September 2016

Navigating Between Scylla and Charybdis; Sevoflurane for Difficult Sedation at the PICU

scientific article published on 01 July 2018

Neonatal Abstinence Syndrome: Update on Diagnostic and Therapeutic Strategies

scientific article published on 18 May 2017

Neonatal Facial Coding System for assessing postoperative pain in infants: item reduction is valid and feasible

scientific article published in November 2003

Neonatal critical illness and development: white matter and hippocampus alterations in school-age neonatal extracorporeal membrane oxygenation survivors.

scientific article published on 21 November 2016

Neonatal extracorporeal membrane oxygenation: impaired health at 5 years of age.

scientific article published in February 2013

Neonatal procedural pain affects state, but not trait anxiety behavior in adult rats

scientific article published in 2021

Neonatal repetitive needle pricking: plasticity of the spinal nociceptive circuit and extended postoperative pain in later life

scientific article

Neurally adjusted ventilatory assist: assessing the comfort and feasibility of use in neonates and children.

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Neurobiologic Correlates of Attention and Memory Deficits Following Critical Illness in Early Life.

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Neurocognitive Outcome After Treatment With(out) ECMO for Neonatal Critical Respiratory or Cardiac Failure

scientific article published on 26 November 2019

Neurodevelopmental Outcome in High-Risk Congenital Diaphragmatic Hernia Patients: An Appeal for International Standardization.

scientific article published on 23 September 2015

Neurodevelopmental, educational and behavioral outcome at 8 years after neonatal ECMO: a nationwide multicenter study

scientific article published on 6 June 2013

Neuroimaging, Pain Sensitivity, and Neuropsychological Functioning in School-Age Neonatal Extracorporeal Membrane Oxygenation Survivors Exposed to Opioids and Sedatives

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Neuropsychological Follow-up After Neonatal ECMO.

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New guidelines for congenital diaphragmatic hernia: what is next?

scholarly article published on 22 January 2024

New perspectives in fetal surgery: The chicken embryo

scientific article published on August 1, 1979

Newborn Babies: More Pain Than That—Reply

article by Sinno H. P. Simons et al published 1 June 2004 in JAMA Pediatrics

Nitrofen-induced diaphragmatic hernias in rats: pulmonary antioxidant enzyme activities

scientific article published on 01 October 1992

Non-VACTERL-type anomalies are frequent in patients with esophageal atresia/tracheo-esophageal fistula and full or partial VACTERL association

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Non-inferiority double-blind randomised controlled trial comparing gabapentin versus tramadol for the treatment of chronic neuropathic or mixed pain in children and adolescents: the GABA-1 trial-a study protocol

scientific article published on 20 February 2019

Non-maturational covariates for dynamic systems pharmacology models in neonates, infants, and children: Filling the gaps beyond developmental pharmacology.

scientific article

Nonselective cyclo-oxygenase inhibitors and glomerular filtration rate in preterm neonates

scientific article (publication date: November 2005)

Numbers, Numbers: Great, Great…But?!

scientific article published on 01 September 2020

Nursing protocol violations: detect, correct and communicate

scientific article

O-demethylation of tramadol in the first months of life.

scientific article

O05 Physiologically based pharmacokinetic modelling to characterize acetaminophen pharmacokinetics and NAPQI formation in non-pregnant and pregnant women

scholarly article

O30 A comprehensive analysis of ontogeny of renal drug transporters: mRNA analyses, quantitative proteomics and localization

scientific article published in 2019

O33 Towards personalised weaning of sedatives and analgesics using mechanism-based modelling of iatrogenic withdrawal in critically ill children

scholarly article

O34 Item response theory modeling; old kid on the block to improve pediatric drug dosing

scholarly article

OC11.05: Abnormal vertebral pattern in genetically heterogeneous deceased fetuses and neonates: evidence of selection against variations

scholarly article

OC31.03: Prediction of postnatal outcome in fetuses with a congenital lung malformation: a two‐year follow‐up study

scholarly article

OP20.10: The validity of the visceroabdominal disproportion ratio for type of surgical closure in all fetuses with an omphalocele

scholarly article

OPRM1 and COMT polymorphisms: implications on postoperative acute, chronic and experimental pain after cardiac surgery

scientific article published on 01 February 2020

Objective and continuous measurement of peripheral motor indicators of pain in hospitalized infants: a feasibility study

scientific article published on 26 October 2007

Observation scales for pain assessment in older adults with cognitive impairments or communication difficulties

scientific article published on January 2007

Observational visual analog scale in pediatric pain assessment: useful tool or good riddance?

scientific article published on September 2002

Observed to expected lung area to head circumference ratio in the prediction of survival in fetuses with isolated diaphragmatic hernia

scientific article published on 01 July 2007

Omphalocele at school age: What do parents report? A call for long-term follow-up of complex omphalocele patients

scientific article published on 30 July 2019

Omphalocele: from diagnosis to growth and development at 2 years of age

scientific article published on 21 March 2018

Ontogeny of hepatic glucuronidation; methods and results

scientific article published on July 2012

Ontogeny of human hepatic and intestinal transporter gene expression during childhood: age matters.

scientific article

Opioid and benzodiazepine withdrawal syndrome: can we predict and prevent it?

scientific article published in February 2015

Optimal sedation in pediatric intensive care patients: a systematic review

scientific article published on 19 June 2013

Oral sucrose for acute pain studied in more than 7000 neonates, but many questions remain

scientific article published on 30 January 2017

Overexpression of lunatic fringe does not affect epithelial cell differentiation in the developing mouse lung.

scientific article published on 10 December 2004

Oxidative injury of the pulmonary circulation in the perinatal period: Short- and long-term consequences for the human cardiopulmonary system

scientific article

P-29: Growth Retardation in Patients with Esophageal Atresia

scientific article published on 01 April 2016

P-34: Motor Performance and Exercise Capacity in Children Born with Esophageal Atresia: A Longitudinal Evaluation

scientific article published on 01 April 2016

P66 Characterization of the pharmacokinetics of acetaminophen and its metabolites in the fetus through integration of placental transfer in a physiologically based pharmacokinetic model

scholarly article

P67 Impact of enantiomer-specific maturational changes in pharmacokinetics on the racemic ketorolac target trough concentration

scholarly article

Paediatric critical incident analysis: lessons learnt on analysis, recommendations and implementation

scientific article published on 31 May 2014

Pain Experience is Somatotopically Organized and Overlaps with Pain Anticipation in the Human Cerebellum

scientific article published on 01 August 2018

Pain Management in Dutch Nursing Homes Leaves Much to Be Desired

Pain Management in Neonatal Intensive Care: Evaluation of the Compliance with Guidelines.

scientific article

Pain and distress caused by endotracheal suctioning in neonates is better quantified by behavioural than physiological items: a comparison based on item response theory modelling

scientific article

Pain control and sedation

scientific article published on 19 May 2006

Pain in Intellectually Disabled Children: Towards Evidence-Based Pharmacotherapy?

scientific article published on 16 June 2015

Pain insensitivity syndrome misinterpreted as inflicted burns

scientific article published on 14 April 2014

Pain management during eye examinations for retinopathy of prematurity: what about procedural adaptations to blunt the pain response?

scientific article published on 07 January 2010

Pain management in intellectually disabled children: Assessment, treatment, and translational research.

scientific article published on January 2010

Pain management in intellectually disabled children: a survey of perceptions and current practices among Dutch anesthesiologists.

scientific article

Pain perception development and maturation.

scientific article

Pain relief in neonates: when to use intravenous paracetamol

scientific article published on 25 March 2011

Pain sensitivity of children with Down syndrome and their siblings: quantitative sensory testing versus parental reports.

scientific article published on 10 June 2015

Paneth cell hyperplasia and metaplasia in necrotizing enterocolitis

scientific article published in March 2011

Paracetamol and metabolite pharmacokinetics in infants.

scientific article published on 22 May 2003

Paracetamol and morphine for infant and neonatal pain; still a long way to go?

scientific article

Paracetamol in Older People: Towards Evidence-Based Dosing?

scientific article published on 01 July 2018

Parental Physical Proximity in End-of-Life Care in the PICU.

scientific article published on 17 February 2016

Parental satisfaction with follow-up services for children with major anatomical congenital anomalies

scientific article published on 31 August 2009

Pathogenetics of alveolar capillary dysplasia with misalignment of pulmonary veins

scientific article

Patient safety culture in a Dutch pediatric surgical intensive care unit: an evaluation using the Safety Attitudes Questionnaire

scientific article

Pediatric Perceived Cognitive Functioning: Psychometric Properties and Normative Data of the Dutch Item Bank and Short Form

scientific article published on 10 June 2019

Pediatric microdose and microtracer studies using 14C in Europe.

scientific article published on 17 July 2015

Pediatric microdose study of [(14)C]paracetamol to study drug metabolism using accelerated mass spectrometry: proof of concept

scientific article

Pediatric pharmacology: current efforts and future goals to improve clinical practice

scientific article

Perceived Motor Competence Differs From Actual Performance in 8-Year-Old Neonatal ECMO Survivors

scientific article published on 12 February 2016

Perinatal maternal stress and serotonin signaling: effects on pain sensitivity in offspring

scientific article published on 06 December 2013

Perioperative management of esophageal atresia/tracheo-esophageal fistula: An analysis of data of 101 consecutive patients

scientific article published on 27 August 2019

Persistent low microcirculatory vessel density in nonsurvivors of sepsis in pediatric intensive care.

scientific article published in January 2011

Persistent postconcussive symptoms in children and adolescents with mild traumatic brain injury receiving initial head computed tomography

scientific article published in 2021

Pharmacodynamic considerations in the treatment of pulmonary hypertension in infants: challenges and future perspectives

scientific article

Pharmacodynamics and Pharmacokinetics of Morphine After Cardiac Surgery in Children With and Without Down Syndrome.

scientific article published on 2 August 2016

Pharmacodynamics of chloral hydrate in former preterm infants

scientific article published on 30 March 2005

Pharmacogenetics and paediatric drug development: issues and consequences to labelling and dosing recommendations.

scientific article published on August 2007

Pharmacokinetic considerations and recommendations in palliative care, with focus on morphine, midazolam and haloperidol.

scientific article published on 15 April 2016

Pharmacokinetic considerations for pediatric patients receiving analgesia in the intensive care unit; targeting postoperative, ECMO and hypothermia patients.

scientific article published on 6 April 2018

Pharmacokinetic modeling of intravenous sildenafil in newborns with congenital diaphragmatic hernia

scientific article published on 18 November 2019

Pharmacokinetics and analgesic effects of intravenous propacetamol vs rectal paracetamol in children after major craniofacial surgery.

scientific article published on 8 May 2008

Pharmacokinetics and pharmacodynamics of midazolam and metabolites in nonventilated infants after craniofacial surgery.

scientific article published in December 2006

Pharmacokinetics of Morphine, Morphine-3-Glucuronide and Morphine-6-Glucuronide in Terminally Ill Adult Patients.

scientific article published on 29 December 2015

Pharmacokinetics of cefotaxime and desacetylcefotaxime in infants during extracorporeal membrane oxygenation.

scientific article

Pharmacokinetics of sufentanil during long-term infusion in critically ill pediatric patients

scientific article

Pharmacological sedation management in the paediatric intensive care unit

scientific article published on 21 August 2016

Pharmacological treatment of neonatal pain: in search of a new equipoise

scientific article

Pharmacotherapy in neonatal and pediatric extracorporeal membrane oxygenation (ECMO).

scientific article published on July 2012

Phenobarbital pharmacokinetics in neonates and infants during extracorporeal membrane oxygenation

scientific article published on 01 May 2018

Physiologically Based Pharmacokinetic Modeling to Characterize Acetaminophen Pharmacokinetics and N-Acetyl-p-Benzoquinone Imine (NAPQI) Formation in Non-Pregnant and Pregnant Women

scientific article published on 01 January 2020

Pilot study on the influence of liver blood flow and cardiac output on the clearance of propofol in critically ill patients

scientific article published on 13 November 2007

Plasma concentrations of oseltamivir and oseltamivir carboxylate in critically ill children on extracorporeal membrane oxygenation support

scientific article

Population Pharmacokinetic Modeling of Acetaminophen and Metabolites in Children After Cardiac Surgery With Cardiopulmonary Bypass

scientific article published on 11 January 2019

Population pharmacodynamic modelling of midazolam induced sedation in terminally ill adult patients.

scientific article published on 27 September 2017

Population pharmacokinetic modelling of intravenous paracetamol in fit older people displays extensive unexplained variability

article

Population pharmacokinetic-pharmacodynamic model of propofol in adolescents undergoing scoliosis surgery with intraoperative wake-up test: a study using Bispectral index and composite auditory evoked potentials as pharmacodynamic endpoints

scientific article published on 22 January 2019

Population pharmacokinetics of haloperidol in terminally ill adult patients.

scientific article

Population pharmacokinetics of intravenous clonidine for sedation during paediatric extracorporeal membrane oxygenation and continuous venovenous hemofiltration.

scientific article published on 12 January 2017

Population pharmacokinetics of midazolam and its metabolites during venoarterial extracorporeal membrane oxygenation in neonates.

scientific article published in June 2010

Population pharmacokinetics of paracetamol across the human age-range from (pre)term neonates, infants, children to adults

scientific article published on 23 January 2014

Postmortem biopsy to obtain lung tissue in congenital diaphragmatic hernia.

scientific article

Postmortem findings and clinicopathological correlation in congenital diaphragmatic hernia

scientific article published on 01 September 2004

Postoperative pain in the neonate: age-related differences in morphine requirements and metabolism

scientific article published on 25 July 2003

Potent inhibition of estrogen sulfotransferase by hydroxylated metabolites of polyhalogenated aromatic hydrocarbons reveals alternative mechanism for estrogenic activity of endocrine disrupters

scientific article published in March 2002

Potentially clinically relevant concentrations of Cefazolin, Midazolam, Propofol, and Sufentanil in auto-transfused blood in congenital cardiac surgery.

scientific article published on 8 June 2018

Pre- and postnatal diagnosis and outcome of fetuses and neonates with esophageal atresia and tracheoesophageal fistula

scientific article published in March 2010

Predicting CYP3A-mediated midazolam metabolism in critically ill neonates, infants, children and adults with inflammation and organ failure.

scientific article

Predicting Unacceptable Pain in Cardiac Surgery Patients Receiving Morphine Maintenance and Rescue Doses: A Model-Based Pharmacokinetic-Pharmacodynamic Analysis

scientific article published on 26 October 2020

Prediction of chronic lung disease, survival and need for ECMO therapy in infants with congenital diaphragmatic hernia: additional value of fetal MRI measurements?

scientific article published in April 2011

Prediction of morphine clearance in the paediatric population : how accurate are the available pharmacokinetic models?

scientific article published on 1 November 2012

Prediction of postnatal outcome in fetuses with a congenital lung malformation: a 2-year follow-up study

scientific article published on 18 November 2020

Prediction of propofol clearance in children from an allometric model developed in rats, children and adults versus a 0.75 fixed-exponent allometric model

scientific article published in April 2010

Predictive Performance of a Recently Developed Population Pharmacokinetic Model for Morphine and its Metabolites in New Datasets of (Preterm) Neonates, Infants and Children.

scientific article published in January 2011

Pregnancy affects the pharmacokinetics of sildenafil and its metabolite in the rabbit.

scientific article

Premature differentiation of vascular smooth muscle cells in human congenital diaphragmatic hernia

scientific article published on 24 September 2012

Prematurity, Opioid Exposure and Neonatal Pain: Do They Affect the Developing Brain?

scientific article published on 11 April 2015

Prenatal Prediction of the Type of Omphalocele Closure by Different Medical Consultants

scientific article

Prenatal exposure to thyroid hormone is necessary for normal postnatal development of murine heart and lungs

scientific article published in August 2004

Prenatal markers and longitudinal follow-up in simple and complex gastroschisis

scientific article published on 14 June 2017

Prenatal prediction of neonatal morbidity in survivors with congenital diaphragmatic hernia: a multicenter study

scientific article published on 01 January 2009

Prenatal prediction of pulmonary hypoplasia: clinical, biometric, and Doppler velocity correlates

scientific article

Prevalence and Implications of Abnormal Laboratory Results in Patients in the Terminal Phase of Life

scientific article published on August 2016

Prevalence and clinical presentation of constipation in children with severe generalized cerebral palsy

scientific article published on 24 May 2010

Prevalence of pain in institutionalized adults with intellectual disabilities: a cross-sectional approach

scientific article

Procedural pain does not raise plasma levels of cortisol or catecholamines in adult intensive care patients after cardiac surgery

scientific article published on 01 January 2016

Proenkephalin as a new biomarker for pediatric acute kidney injury - reference values and performance in children under one year of age

scientific article published on 29 June 2020

Proof of concept: first pediatric [14 C]microtracer study to create metabolite profiles of midazolam

scientific article published on 09 May 2020

Propofol pharmacokinetics and pharmacodynamics for depth of sedation in nonventilated infants after major craniofacial surgery.

scientific article published in March 2006

Propofol pharmacokinetics in preterm and term neonates: the relevance of both postmenstrual and postnatal age.

scientific article published on 13 March 2008

Prospective evaluation of faecal fatty acid excretion in short bowel syndrome in newborns

scientific article published on 01 April 1996

Prospective evaluation of surfactant composition in bronchoalveolar lavage fluid of infants with congenital diaphragmatic hernia and of age-matched controls

scientific article published on 01 March 1998

Prospective evaluation of the absorptive capacity of the bowel after major and minor resections in the neonate

scientific article published on 01 March 1995

Prospective longitudinal evaluation of lung function during the first year of life after extracorporeal membrane oxygenation

scientific article published in March 2011

Prospective longitudinal evaluation of lung function during the first year of life after repair of congenital diaphragmatic hernia

scientific article published on 01 May 2012

Proteomic Analysis of the Developmental Trajectory of Human Hepatic Membrane Transporter Proteins in the First Three Months of Life

scientific article published on 21 April 2016

Proteomics of human liver membrane transporters: a focus on fetuses and newborn infants

scientific article published in November 2018

Protocolized post-operative pain management in infants; do we stick to it?

scientific article published on 19 December 2011

Psychometric evaluation of the Sophia Observation withdrawal symptoms scale in critically ill children

scientific article published in October 2013

Pulmonary function and exercise capacity in survivors of congenital diaphragmatic hernia

scientific article published on 12 March 2009

Pulmonary hypertension associated with congenital diaphragmatic hernia

scientific article published on 01 May 2009

Pulmonary hypertension in human newborns with congenital diaphragmatic hernia is associated with decreased vascular expression of nitric-oxide synthase

scientific article published on 01 January 2006

Pulmonary hypoplasia secondary to oligohydramnios with very premature rupture of fetal membranes

scientific article published on April 1990

Pulmonary surfactant protein A, B, and C mRNA and protein expression in the nitrofen-induced congenital diaphragmatic hernia rat model

scientific article published on 6 August 2003

Pulmonary vascular abnormalities in experimentally induced congenital diaphragmatic hernia in rats

scientific article published on July 1, 1992

Pulmonary vascular development goes awry in congenital lung abnormalities

scientific article

Pulmonary vascular development in congenital diaphragmatic hernia

scientific article published on 24 January 2018

Pulmonary ventilation and micro-structural findings in congenital diaphragmatic hernia.

scientific article published on 9 October 2015

Randomized Controlled Trial Comparing Different Single Doses of Intravenous Paracetamol for Placement of Peripherally Inserted Central Catheters in Preterm Infants.

scientific article published on 31 May 2017

Randomized Controlled Trial on the Influence of Intraoperative Remifentanil versus Fentanyl on Acute and Chronic Pain after Cardiac Surgery

scientific article published on 25 July 2017

Rapid Increase in Clearance of Phenobarbital in Neonates on Extracorporeal Membrane Oxygenation: A Pilot Retrospective Population Pharmacokinetic Analysis

scientific article published on 26 June 2020

Real-time registration of adverse events in Dutch hospitalized children in general pediatric units: first experiences

scientific article published on 22 October 2011

Recovery of cefazolin and clindamycin in in vitro pediatric CPB systems

scientific article published on 06 January 2020

Rectal Omeprazole in Infants With Gastroesophageal Reflux Disease: A Randomized Pilot Trial

scientific article published on 27 June 2020

Rectal acetaminophen does not reduce morphine consumption after major surgery in young infants.

scientific article published on 6 February 2007

Reference intervals for renal injury biomarkers neutrophil gelatinase-associated lipocalin and kidney injury molecule-1 in young infants

scientific article published on July 2015

Reference ranges for serum β-trace protein in neonates and children younger than 1 year of age.

scientific article published in December 2014

Remifentanil during cardiac surgery is associated with chronic thoracic pain 1 yr after sternotomy

scientific article

Remifentanil to relieve pain associated with peripherally inserted central catheters in preterm infants: the new way to go?*.

scientific article published in June 2014

Remifentanil versus fentanyl during cardiac surgery on the incidence of chronic thoracic pain (REFLECT): study protocol for a randomized controlled trial

scientific article published on 27 November 2014

Repeated touch and needle prick stimulation in the neonatal period increases the baseline mechanical sensitivity and post-injury hypersensitivity of adult spinal sensory neurons.

scientific article published on 8 March 2018

Repetitive noxious stimuli during early development affect acute and long-term mechanical sensitivity in rats

scientific article published on 13 May 2019

Reply

Reproducibility of microvascular vessel density analysis in Sidestream dark-field-derived images of healthy term newborns.

scientific article published in January 2015

Rescue morphine in mechanically ventilated newborns associated with combined OPRM1 and COMT genotype

scientific article published on 01 July 2014

Respiratory morbidity and growth after open thoracotomy or thoracoscopic repair of esophageal atresia

scientific article published on 01 November 2012

Retinol status of newborn infants is associated with congenital diaphragmatic hernia

scientific article published on 13 September 2010

Reversal of pulmonary vascular remodeling in pulmonary hypertensive rats

scientific article published on 27 March 2012

Risk Factors of Impaired Neuropsychologic Outcome in School-Aged Survivors of Neonatal Critical Illness

scientific article published on 30 November 2017

Risk and relevance of open lung biopsy in pediatric ECMO patients: the Dutch experience

scientific article published on 14 November 2016

Risk factors for chronic lung disease and mortality in newborns with congenital diaphragmatic hernia

scientific article published on October 30, 2010

Role of nutrition, lifestyle factors, and genes in the pathogenesis of congenital diaphragmatic hernia: human and animal studies

scientific article published on December 2009

Role of oxygen and vascular development in epithelial branching morphogenesis of the developing mouse lung

scientific article published on 17 September 2004

Routine Intubation in Newborns With Congenital Diaphragmatic Hernia

scientific article published on 22 September 2020

Routine enteral nutrition in neonates on extracorporeal membrane oxygenation

scientific article

Routine morphine infusion in preterm newborns who received ventilatory support: a randomized controlled trial

scientific article published in November 2003

SLC22A1/OCT1 Genotype Affects O-desmethyltramadol Exposure in Newborn Infants

scientific article published on 01 August 2016

SOX2 redirects the developmental fate of the intestinal epithelium toward a premature gastric phenotype

scientific article published on 7 June 2012

Safeguarding children's right to health in hospital during COVID-19

scientific article published on 14 September 2020

Salivary cortisol in children with cognitive impairment.

scientific article

Sample collection, biobanking, and analysis

scientific article published on January 2011

Scaling Drug Clearance from Adults to the Young Children for Drugs Undergoing Hepatic Metabolism: A Simulation Study to Search for the Simplest Scaling Method

scientific article published on 08 March 2019

Score for Neonatal Acute Physiology-II Predicts Outcome in Congenital Diaphragmatic Hernia Patients

scientific article

Searching the right way to treat neonatal abstinence syndrome*

scientific article published on 01 February 2014

Second consensus on the assessment of sublingual microcirculation in critically ill patients: results from a task force of the European Society of Intensive Care Medicine

scientific article published on 6 February 2018

Sedation With Midazolam After Cardiac Surgery in Children With and Without Down Syndrome: A Pharmacokinetic-Pharmacodynamic Study

scientific article published on 08 October 2020

Sedation and analgesia in the PICU: many questions remain

Selective Targeting of Serotonin 5-HT1a and 5-HT3 Receptors Attenuates Acute and Long-Term Hypersensitivity Associated With Neonatal Procedural Pain

scientific article published in 2022

Sensorineural hearing loss and language development following neonatal extracorporeal membrane oxygenation

scientific article published in January 2013

Sequestration of Voriconazole and Vancomycin Into Contemporary Extracorporeal Membrane Oxygenation Circuits: An in vitro Study

scientific article published on 27 August 2020

Severity of asphyxia is a covariate of phenobarbital clearance in newborns undergoing hypothermia

scientific article published on 22 January 2018

Severity parameters for asphyxia or hypoxic-ischemic encephalopathy do not explain interindividual variability in the pharmacokinetics of phenobarbital in newborns treated with therapeutic hypothermia

scientific article published on 27 October 2020

Sex differences in inflammatory mechanical hypersensitivity in later life of rats exposed to repetitive needle pricking as neonates

scientific article published in May 2012

Short- and long-term impact of remifentanil on thermal detection and pain thresholds after cardiac surgery: A randomised controlled trial

scientific article published on 01 January 2019

Short-Term Health-Related Quality of Life of Critically Ill Children Following Daily Sedation Interruption

scientific article published on 22 September 2016

Should we use criteria or eyeballing to reject post-interruption tracings?

scientific article published on 01 October 2006

Sildenafil exposure in neonates with pulmonary hypertension after administration via a nasogastric tube

scientific article published on 30 November 2009

Simultaneous assay of sildenafil and desmethylsildenafil in neonatal plasma by ultra-performance liquid chromatography-tandem mass spectrometry

scientific article

Skin conductance peaks could result from changes in vital parameters unrelated to pain

scientific article published on 15 February 2012

Small intestinal MUC2 synthesis in human preterm infants

scientific article published on 26 February 2009

Small noncoding differentially methylated copy-number variants, including lncRNA genes, cause a lethal lung developmental disorder

scientific article

Sophia Observation withdrawal Symptoms-Paediatric Delirium scale: A tool for early screening of delirium in the PICU.

scientific article published on 23 August 2017

Sox2 is important for two crucial processes in lung development: branching morphogenesis and epithelial cell differentiation

scientific journal article

Sox2 regulates the emergence of lung basal cells by directly activating the transcription of Trp63.

scientific article published on August 2014

Spatial and temporal expression of glucocorticoid, retinoid, and thyroid hormone receptors is not altered in lungs of congenital diaphragmatic hernia

scientific article published on 25 October 2006

Sphingolipids in Congenital Diaphragmatic Hernia; Results from an International Multicenter Study

scientific article

Splanchnic bed metabolism of glucose in preterm neonates

scientific article published on 01 May 2004

Standard and individually determined thermal pain stimuli induce similar brain activations

scientific article

Standardized Postnatal Management of Infants with Congenital Diaphragmatic Hernia in Europe: The CDH EURO Consortium Consensus - 2015 Update

scientific article

Standardized postnatal management of infants with congenital diaphragmatic hernia in Europe: the CDH EURO Consortium consensus

scientific article published on October 27, 2010

Standardized reporting for congenital diaphragmatic hernia--an international consensus

scientific article published on December 2013

Steam inhalation therapy: severe scalds as an adverse side effect

scientific article

Strategy for management of newborns with cervical teratoma

scientific article

Striving for an effective but parsimonious use of sedation in pediatric intensive care.

scientific article published on 31 March 2016

Structural and numerical changes of chromosome X in patients with esophageal atresia

scientific article

Successful Use of [14C]Paracetamol Microdosing to Elucidate Developmental Changes in Drug Metabolism

scientific article published on 2 February 2017

Supervised Multidimensional Item Response Theory Modeling of Pediatric Iatrogenic Withdrawal Symptoms

scientific article published on 15 October 2019

Surfactant does not improve survival rate in preterm infants with congenital diaphragmatic hernia.

scientific article published on June 2004

Surfactant phosphatidylcholine metabolism in neonates with meconium aspiration syndrome.

scientific article

Surfactant phosphatidylcholine pool size in human neonates with congenital diaphragmatic hernia requiring ECMO.

scientific article published in March 2003

Surfactant replacement therapy in high-risk congenital diaphragmatic hernia

scientific article published on 01 November 1991

Surfactant replacement therapy on ECMO does not improve outcome in neonates with congenital diaphragmatic hernia

scientific article published in November 2004

Survival after non-aggressive obstetric management in cases of severe fetal anomalies: a retrospective study

scientific article published in December 2005

Systematic evaluation of pain in neonates: effect on the number of intravenous analgesics prescribed

scientific article published on 4 April 2003

Systematic evaluation of the descriptive and predictive performance of paediatric morphine population models

scientific article

TGF-beta signaling is dynamically regulated during the alveolarization of rodent and human lungs

scientific article

Tailor-made drug treatment for children: creation of an infrastructure for data-sharing and population PK-PD modeling

scientific article

Taking Up the Challenge of Measuring Prolonged Pain in (Premature) Neonates

Telephone helpline for parents of children with congenital anomalies

scientific article published on 01 December 2008

The CLOSED trial; CLOnidine compared with midazolam for SEDation of paediatric patients in the intensive care unit: study protocol for a multicentre randomised controlled trial

scientific article published on 21 June 2017

The COMFORT Behavior Scale: a tool for assessing pain and sedation in infants

scientific article published on 01 January 2005

The COMFORT behavior scale: is a shorter observation period feasible?.

scientific article published in March 2012

The COMFORT behaviour scale detects clinically meaningful effects of analgesic and sedative treatment.

scientific article published on 29 July 2014

The COMFORT-Behavior scale is useful to assess pain and distress in 0- to 3-year-old children with Down syndrome

scientific article published on 02 June 2011

The CoDiNOS trial protocol: an international randomised controlled trial of intravenous sildenafil versus inhaled nitric oxide for the treatment of pulmonary hypertension in neonates with congenital diaphragmatic hernia

scientific article published on 05 November 2019

The Critically Ill Adults scale.

scientific article published on 7 March 2005

The Future of Bronchopulmonary Dysplasia: Emerging Pathophysiological Concepts and Potential New Avenues of Treatment.

scientific article

The Impact of Hypothermia on the Pharmacokinetics of Drugs Used in Neonates and Young Infants.

scientific article published on September 2015

The Importance of Parental Connectedness and Relationships With Healthcare Professionals in End-of-Life Care in the PICU.

scientific article published on 11 January 2018

The Microcirculation Is Unchanged in Neonates with Severe Respiratory Failure after the Initiation of ECMO Treatment

scientific article

The Rotterdam Elderly Pain Observation Scale (REPOS) is reliable and valid for non-communicative end-of-life patients.

scientific article

The Sublingual Microcirculation Throughout Neonatal and Pediatric Extracorporeal Membrane Oxygenation Treatment: Is It Altered by Systemic Extracorporeal Support?

scientific article published on 10 July 2019

The VICI-trial: high frequency oscillation versus conventional mechanical ventilation in newborns with congenital diaphragmatic hernia: an international multicentre randomized controlled trial

scientific article

The Val158Met polymorphism of the COMT gene is associated with increased pain sensitivity in morphine-treated patients undergoing a painful procedure after cardiac surgery.

scientific article published on June 2013

The allometric exponent for scaling clearance varies with age: a study on seven propofol datasets ranging from preterm neonates to adults

scientific article published on January 2014

The auditory evoked potential monitor: first data from infants outside the operation room

scientific article published on 01 November 2006

The authors reply

The co-occurrence of congenital diaphragmatic hernia, esophageal atresia/tracheoesophageal fistula, and lung hypoplasia.

scientific article published on January 2005

The cost-effectiveness of treatment for congenital diaphragmatic hernia.

scientific article published in September 2002

The current practice regarding neuro-prognostication for comatose children after cardiac arrest differs between and within European PICUs: A survey

scientific article published on 08 July 2020

The development of descending serotonergic modulation of the spinal nociceptive network: a life span perspective

scientific article published in 2021

The developmental and biological basis of pediatric surgery. Preface.

scientific article published in August 2010

The effect of adult and pediatric cardiopulmonary bypass on pharmacokinetic and pharmacodynamic parameters

scientific article

The effect of critical illness and inflammation on midazolam therapy in children

scientific article published in January 2012

The effect of cumulative energy and protein deficiency on anthropometric parameters in a pediatric ICU population

scientific article published on 01 December 2004

The effect of experimentally induced intestinal perforation at an early developmental stage

scientific article published on 01 December 1981

The effect of inflammation on drug metabolism: a focus on pediatrics

scientific article published on March 2011

The effect of maternal betamethasone and fetal tracheal occlusion on pulmonary vascular morphometry in fetal rabbits with surgically induced diaphragmatic hernia: a placebo controlled morphologic study

scientific article

The effects of analgesia in the vulnerable infant during the perinatal period.

scientific article

The etiology of congenital diaphragmatic hernia: still largely unknown?

scientific article published on 21 May 2009

The fragile spirituality of parents whose children died in the pediatric intensive care unit

scientific article published on 04 October 2019

The gap in referral criteria for pediatric intestinal transplantation

scientific article

The impact of extracorporeal life support and hypothermia on drug disposition in critically ill infants and children.

scientific article published on 29 August 2012

The lungs in congenital diaphragmatic hernia: do we understand?

scientific article published on 01 September 1998

The occurrence of adverse events in low-risk non-survivors in pediatric intensive care patients: an exploratory study

scientific article published on 26 June 2018

The oral bioavailability and metabolism of midazolam in stable critically ill children: a pharmacokinetic microtracing study

scientific article published on 13 May 2020

The outcome of gastroschisis after a prenatal diagnosis or a diagnosis only at birth. Recommendations for prenatal surveillance

scientific article published on 20 February 2008

The prognosis of oncologic patients in the pediatric intensive care unit

scientific article published on 01 March 1996

The pulmonary mesenchymal tissue layer is defective in an in vitro recombinant model of nitrofen-induced lung hypoplasia

scientific article published on 04 November 2011

The relation between viscero-abdominal disproportion and type of omphalocele closure.

scientific article

The role of initial monitoring of routine biochemical nutritional markers in critically ill children

scientific article published on 13 June 2005

The shortened EMpowerment of PArents in THe Intensive Care 30 questionnaire adequately measured parent satisfaction in pediatric intensive care units

scientific article published on 21 June 2013

The timing of ostomy closure in infants with necrotizing enterocolitis: a systematic review

scientific article published on 21 April 2012

The transcription factor GATA6 is essential for branching morphogenesis and epithelial cell differentiation during fetal pulmonary development

scientific article (publication date: February 2001)

The use of comparative genomic hybridization and fluorescent in situ hybridization in postmortem pathology investigation of congenital malformations

scientific article published on 01 March 2010

The use of the Behavioral Pain Scale to assess pain in conscious sedated patients.

scientific article published on 6 November 2009

The validity of the observed-to-expected lung-to-head ratio in congenital diaphragmatic hernia in an era of standardized neonatal treatment; a multicenter study.

scientific article published on 28 April 2017

The validity of the viscero-abdominal disproportion ratio for type of surgical closure in all fetuses with an omphalocele

scientific article published on 29 August 2019

The vulnerable microcirculation in the critically ill pediatric patient

scientific article

Therapeutic Drug Monitoring in Neonates: what makes them unique?

scientific article published on 26 September 2017

Therapeutic targets in neonatal pulmonary hypertension: linking pathophysiology to clinical medicine

scientific article published on February 2008

Thermal detection thresholds in 5-year-old preterm born children; IQ does matter

scientific article published on 13 January 2012

Thermal quantitative sensory testing in healthy Dutch children and adolescents standardized test paradigm and Dutch reference values

scientific article

Thoracoscopic repair in congenital diaphragmatic hernia: patching is safe and reduces the recurrence rate.

scientific article published in May 2010

Timing and Cause of Death in Children Following Return of Circulation After Out-of-Hospital Cardiac Arrest: A Single-Center Retrospective Cohort Study

scientific article published on 07 October 2020

Towards evidence-based dosing regimens in children on the basis of population pharmacokinetic pharmacodynamic modelling

scientific article

Towards integrative neuromonitoring of the surgical newborn: A systematic review

scientific article published on 13 May 2020

Towards integrative physiological monitoring of the critically ill: from cardiovascular to microcirculatory and cellular function monitoring at the bedside.

scientific article published on 12 March 2013

Towards personalized treatment of pain using a quantitative systems pharmacology approach.

scientific article

Training-induced white matter microstructure changes in survivors of neonatal critical illness: A randomized controlled trial

scientific article published on 27 June 2019

Tramadol concentrations in blood and in cerebrospinal fluid in a neonate.

scientific article published on 21 January 2005

Tramadol disposition in the very young: an attempt to assess in vivo cytochrome P-450 2D6 activity.

scientific article

Transcription Factor SOX2 Affects the Developmental Fate of Intestinal Epithelium

scholarly article published in May 2011

Traumatic brain injury: integrated approaches to improve prevention, clinical care, and research

scientific article published on 6 November 2017

Treatment of rat congenital diaphragmatic hernia with sildenafil and NS-304, selexipag's active compound, at the pseudoglandular stage improves lung vasculature

scientific article published on 10 May 2018

Trial Recruitment in the Pediatric Intensive Care: Ask Consent Before You Start?!

scientific article

Ultrasound markers predicting complex gastroschisis and adverse outcome: a longitudinal prospective nationwide cohort study

scientific article published on 15 October 2019

Unique Tracheal Fluid MicroRNA Signature Predicts Response to FETO in Patients With Congenital Diaphragmatic Hernia.

scientific article published on 5 January 2015

Universal Follow-Up After Extracorporeal Membrane Oxygenation: Baby Steps Toward Establishing an International Standard of Care

scientific article published in November 2017

Unraveling the Genetics of Congenital Diaphragmatic Hernia: An Ongoing Challenge

scientific article published in 2022

Update in pediatric lung disease 2009.

scientific article published on April 2010

Update in pediatric lung disease 2013.

scientific article published on May 2014

Update on pain assessment in sick neonates and infants

scientific article published on 22 August 2012

Urinary Neutrophil Gelatinase-Associated Lipocalin Predicts Renal Injury Following Extracorporeal Membrane Oxygenation

scientific article published on 26 June 2015

Urinary neutrophil gelatinase-associated lipocalin identifies critically ill young children with acute kidney injury following intensive care admission: a prospective cohort study

scientific article published on 21 April 2015

Urogenital tract abnormalities associated with esophageal atresia and tracheoesophageal fistula.

scientific article published on February 1989

Using three-dimensional ultrasound in predicting complex gastroschisis: A longitudinal, prospective, multicenter cohort study

scientific article published on 25 October 2019

VACTERL Association Etiology: The Impact of de novo and Rare Copy Number Variations

scientific article published on February 2013

Validation of a Prediction Rule for Mortality in Congenital Diaphragmatic Hernia

scientific article published on 05 March 2020

Validation of disease-specific biomarkers for the early detection of bronchopulmonary dysplasia

scientific article published in 2022

Validation of skinfold measurements and bioelectrical impedance analysis in children with severe cerebral palsy: a review

scientific article published on 14 August 2009

Validation of the Direct Nasopharyngeal Sampling Method for Collection of Expired Air in Preterm Neonates

scientific article published on November 6, 2003

Validation of the Rotterdam Elderly Pain Observation Scale in the Hospital Setting

scientific article published on 13 January 2019

Validation of the SOS-PD scale for assessment of pediatric delirium: a multicenter study

Valproic acid-induced hyperammonemic encephalopathy in a full-term neonate: a brief review and case report.

scientific article

Variability in pain expression characteristics in former preterm infants.

scientific article published in January 2005

Vascular abnormalities in human newborns with pulmonary hypertension

scientific article published on April 2011

Videomicroscopic investigation of the microcirculation requires uniform definitions

scientific article published on June 2017

Vitamin A decreases the incidence and severity of nitrofen-induced congenital diaphragmatic hernia in rats.

scientific article

Weaning of opioids and benzodiazepines at home after critical illness in infants: a cost-effective approach.

scientific article published in January 2010

What is the dose of intravenous paracetamol for pain relief in neonates?

scientific article published on 26 May 2017

Whole-exome resequencing reveals recessive mutations in TRAP1 in individuals with CAKUT and VACTERL association

scientific article published on 23 October 2013

Withdrawal symptoms in children after long-term administration of sedatives and/or analgesics: a literature review. "Assessment remains troublesome"

scientific article

Withdrawal symptoms in critically ill children after long-term administration of sedatives and/or analgesics: a first evaluation

scientific article

Working Memory Training Following Neonatal Critical Illness: A Randomized Controlled Trial.

scientific article published on 5 April 2018

['Acute respiratory distress syndrome' (ARDS) as a serious complication of influenza]

scientific article published on 01 January 2009

['Acute respiratory distress syndrome' (ARDS) as a serious complication of influenza]

scientific article published on 01 January 2010

[Individualized dosing guidelines for children]

scientific article published in January 2013

[Multidisciplinary care of patient's safety at the child intensive care]

scientific article published on 01 February 2009