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List of works by Irving Weissman

"Velcro" engineering of high affinity CD47 ectodomain as signal regulatory protein α (SIRPα) antagonists that enhance antibody-dependent cellular phagocytosis

scientific article published on 2 April 2015

31st Annual Meeting and Associated Programs of the Society for Immunotherapy of Cancer (SITC 2016): part one

scientific article (publication date: November 2016)

A CD47-associated super-enhancer links pro-inflammatory signalling to CD47 upregulation in breast cancer

scientific article published on 05 April 2017

A Mechanism for Somatic Brain Mosaicism

scientific article published in February 2016

A Roadmap for Human Liver Differentiation from Pluripotent Stem Cells

scientific article published in February 2018

A cell-surface molecule involved in organ-specific homing of lymphocytes. 1983.

scientific article published on July 2006

A functional subset of CD8 T cells during chronic exhaustion is defined by SIRPα expression

scientific article published in Nature Communications

A molecular cell atlas of the human lung from single cell RNA sequencing

scientific article

A molecular cell atlas of the human lung from single-cell RNA sequencing

scientific article published on 18 November 2020

A neurosurgeon's guide to stem cells, cancer stem cells, and brain tumor stem cells

scientific article published on August 2009

A role for Wnt signalling in self-renewal of haematopoietic stem cells ⬇️

scientific article published on April 27, 2003

Abstract 140: identification, characterization, and prospective isolation of a fibroblast lineage contributing to dermal development, cutaneous scarring, radiation fibrosis, and cancer stroma

scientific article published on 01 March 2014

Abstract 161: identification of cell-intrinsic mechanisms and differentially regulated genetic pathways responsible for the age-related functional decline in aged skeletal stem cells

scientific article published on 01 March 2014

Abstract 89

Abstract: ATAC-seq Reveals Heterogeneity of Fibroblasts During Transition from Scarless Fetal to Scar-Forming Adult Wound Repair.

scientific article

Adult stem cells and regenerative medicine-a symposium report

scientific article published on 26 October 2019

Age-associated changes in human hematopoietic stem cells

scientific article published on 20 October 2016

An antibody against SSEA-5 glycan on human pluripotent stem cells enables removal of teratoma-forming cells

scientific article published on 14 August 2011

An atlas of transcriptional, chromatin accessibility, and surface marker changes in human mesoderm development

scientific article published on 20 December 2016

Antagonistic effect of CCAAT enhancer-binding protein-alpha and Pax5 in myeloid or lymphoid lineage choice in common lymphoid progenitors

scientific article

Anti-CD117 antibody depletes normal and myelodysplastic syndrome human hematopoietic stem cells in xenografted mice

scientific article published on 11 February 2019

Anti-CD47 Treatment Stimulates Phagocytosis of Glioblastoma by M1 and M2 Polarized Macrophages and Promotes M1 Polarized Macrophages In Vivo.

scientific article

Anti-CD47 antibody synergizes with rituximab to promote phagocytosis and eradicate non-Hodgkin lymphoma

scientific article

Anti-CD47 antibody-mediated phagocytosis of cancer by macrophages primes an effective antitumor T-cell response

scientific article

Anti-GD2 synergizes with CD47 blockade to mediate tumor eradication

scientific article published in 2022

Anti-KIT monoclonal antibody inhibits imatinib-resistant gastrointestinal stromal tumor growth

scientific article published on 4 February 2013

Anti-SIRPα antibody immunotherapy enhances neutrophil and macrophage antitumor activity

scientific article published on 20 November 2017

Anti-human CD117 antibody-mediated bone marrow niche clearance in nonhuman primates and humanized NSG mice

scientific article published on 07 January 2019

Antibody Conditioning Enables MHC-Mismatched Hematopoietic Stem Cell Transplants and Organ Graft Tolerance

scientific article published on 13 June 2019

Antibody Therapy Targeting CD47 and CD271 Effectively Suppresses Melanoma Metastasis in Patient-Derived Xenografts.

scientific article

Antibody therapy targeting the CD47 protein is effective in a model of aggressive metastatic leiomyosarcoma

scientific article

Articular cartilage regeneration by activated skeletal stem cells

scientific article published on 17 August 2020

Association of reactive oxygen species levels and radioresistance in cancer stem cells

scientific article (publication date: 9 April 2009)

Automated microfluidic chromatin immunoprecipitation from 2,000 cells.

scientific article published on 27 February 2009

BCL-2 and Mutant NRAS Interact Physically and Functionally in a Mouse Model of Progressive Myelodysplasia

scientific article published on 01 December 2007

BIOLOGY OF HEMATOPOIETIC STEM CELLS AND PROGENITORS: Implications for Clinical Application

scientific article (publication date: April 2003)

BLT-humanized C57BL/6 Rag2-/-γc-/-CD47-/- mice are resistant to GVHD and develop B- and T-cell immunity to HIV infection

scientific article published on 10 September 2013

Bmi-1-green fluorescent protein-knock-in mice reveal the dynamic regulation of bmi-1 expression in normal and leukemic hematopoietic cells

scientific article published on 29 March 2007

Breaking Down the Barriers to Precision Cancer Nanomedicine.

scientific article

Brief Report: External Beam Radiation Therapy for the Treatment of Human Pluripotent Stem Cell-Derived Teratomas

scientific article

CD14-expressing cancer cells establish the inflammatory and proliferative tumor microenvironment in bladder cancer

scientific article

CD24 signalling through macrophage Siglec-10 is a target for cancer immunotherapy

scientific article published on 31 July 2019

CD47 Blockade by Hu5F9-G4 and Rituximab in Non-Hodgkin's Lymphoma

scientific article published on 01 November 2018

CD47 is an adverse prognostic factor and therapeutic antibody target on human acute myeloid leukemia stem cells.

scientific article published on July 2009

CD47 is upregulated on circulating hematopoietic stem cells and leukemia cells to avoid phagocytosis

scientific article

CD47-Targeted Near-Infrared Photoimmunotherapy for Human Bladder Cancer

scientific article published on 19 March 2019

CD47-blocking antibodies restore phagocytosis and prevent atherosclerosis

scientific article published on 20 July 2016

CD47-blocking immunotherapies stimulate macrophage-mediated destruction of small-cell lung cancer

scientific article published on 13 June 2016

CD47-blocking therapies stimulate macrophage cytokine secretion and are effective in a model of peritoneal carcinomatosis

scientific article

CD96 is a leukemic stem cell-specific marker in human acute myeloid leukemia

scholarly article

Calreticulin Is the Dominant Pro-Phagocytic Signal on Multiple Human Cancers and Is Counterbalanced by CD47 ⬇️

scientific article published on December 22, 2010

Cancer stem cell-directed therapies: recent data from the laboratory and clinic

scientific article

Cancer stem cells in bladder cancer: a revisited and evolving concept

scientific article

Cancer stem cells--perspectives on current status and future directions: AACR Workshop on cancer stem cells

scientific article

Cell intrinsic alterations underlie hematopoietic stem cell aging.

scientific article

Changes in integrin expression are associated with altered homing properties of Lin(-/lo)Thy1.1(lo)Sca-1(+)c-kit(+) hematopoietic stem cells following mobilization by cyclophosphamide/granulocyte colony-stimulating factor

scientific article published in February 2002

Characterization of mouse clonogenic megakaryocyte progenitors

scientific article

Cholinergic activation of hematopoietic stem cells: role in tobacco-related disease?

scientific article

Chronic versus acute myelogenous leukemia: a question of self-renewal

scientific article published in December 2004

Circulation and chemotaxis of fetal hematopoietic stem cells

scientific article

Clonal analysis reveals nerve-dependent and independent roles on mammalian hind limb tissue maintenance and regeneration.

scientific article

Clonal evolution of preleukemic hematopoietic stem cells precedes human acute myeloid leukemia.

scientific article

Clonal precursor of bone, cartilage, and hematopoietic niche stromal cells.

scientific article published on 15 July 2013

Clonal reversal of ageing-associated stem cell lineage bias via a pluripotent intermediate

scientific article

Clonal tracking of rhesus macaque hematopoiesis highlights a distinct lineage origin for natural killer cells

scientific article published on April 2014

Clonal-level lineage commitment pathways of hematopoietic stem cells in vivo

scientific article published on 08 January 2019

Clonally expanding smooth muscle cells promote atherosclerosis by escaping efferocytosis and activating the complement cascade

scientific article published on 15 June 2020

Common lymphoid progenitors rapidly engraft and protect against lethal murine cytomegalovirus infection after hematopoietic stem cell transplantation

scientific article published on 27 March 2003

Complex mammalian-like haematopoietic system found in a colonial chordate

scientific article published on 05 December 2018

Comprehensive methylome map of lineage commitment from haematopoietic progenitors

scientific article

Computational correction of index switching in multiplexed sequencing libraries

scientific article published on 01 April 2018

Continuous development precludes radioprotection in a colonial ascidian

scientific article published on 01 March 2004

Coronary arteries form by developmental reprogramming of venous cells

scientific article published on March 2010

Cyclical generation and degeneration of organs in a colonial urochordate involves crosstalk between old and new: a model for development and regeneration

scientific article published on 01 September 2002

Cyclin-A1 represents a new immunogenic targetable antigen expressed in acute myeloid leukemia stem cells with characteristics of a cancer-testis antigen ⬇️

scientific article published on April 23, 2012

De novo mutations in mitochondrial DNA of iPSCs produce immunogenic neoepitopes in mice and humans

scientific article published on 19 August 2019

Decoupling the Functional Pleiotropy of Stem Cell Factor by Tuning c-Kit Signaling

scientific article published in March 2017

Deficiencies in DNA damage repair limit the function of haematopoietic stem cells with age

scientific journal article

Delivery of monocyte lineage cells in a biomimetic scaffold enhances tissue repair

scientific article published on 5 October 2017

Depletion of host Langerhans cells before transplantation of donor alloreactive T cells prevents skin graft-versus-host disease

scientific article published on 18 April 2004

Determinants of skeletal muscle contributions from circulating cells, bone marrow cells, and hematopoietic stem cells

scientific article published in January 2004

Developmental cell death programs license cytotoxic cells to eliminate histocompatible partners

scientific article published on 23 May 2016

Developmental origin of interferon-alpha-producing dendritic cells from hematopoietic precursors

scientific article published in February 2005

Developmental plasticity of lymphoid progenitors

scientific article

Differential DNA damage response in stem and progenitor cells

scientific article published on 01 August 2010

Differential expression of alpha2 integrin separates long-term and short-term reconstituting Lin-/loThy1.1(lo)c-kit+ Sca-1+ hematopoietic stem cells

scientific article

Differential expression of novel potential regulators in hematopoietic stem cells

scientific article

Discriminating cellular heterogeneity using microwell-based RNA cytometry

scientific article published on 25 March 2014

Disrupting the CD47-SIRPα anti-phagocytic axis by a humanized anti-CD47 antibody is an efficacious treatment for malignant pediatric brain tumors.

scientific article

Distinguishing mast cell and granulocyte differentiation at the single-cell level

scientific article

Do pluripotent stem cells exist in adult mice as very small embryonic stem cells?

scientific article

Dynamic Patterns of Clonal Evolution in Tumor Vasculature Underlie Alterations in Lymphocyte-Endothelial Recognition to Foster Tumor Immune Escape

scientific article published on 30 December 2015

Dysregulated integrin αVβ3 and CD47 signaling promotes joint inflammation, cartilage breakdown, and progression of osteoarthritis

scientific article published on 19 September 2019

E. Donnall Thomas (1920–2012) ⬇️

scientific article published on November 29, 2012

E2A proteins maintain the hematopoietic stem cell pool and promote the maturation of myelolymphoid and myeloerythroid progenitors

scholarly article

Early Defect Prethymic in Bone Marrow T Cell Progenitors in Athymic nu/nu Mice

scientific article published on 01 August 2003

Early TCR expression and aberrant T cell development in mice with endogenous prerearranged T cell receptor genes

scientific article published on 01 July 2007

Effects of ultra-high dose rate FLASH irradiation on the tumor microenvironment in Lewis lung carcinoma: role of myosin light chain

scientific article published on 10 November 2020

Efficient endoderm induction from human pluripotent stem cells by logically directing signals controlling lineage bifurcations.

scientific article

Efficient transplantation via antibody-based clearance of hematopoietic stem cell niches

scientific article published on November 2007

Elucidation of the phenotypic, functional, and molecular topography of a myeloerythroid progenitor cell hierarchy.

scientific article

En1 fibroblasts and melanoma.

scientific article

Endochondral ossification is required for haematopoietic stem-cell niche formation

scientific article

Endogenous Wnt signalling in human embryonic stem cells generates an equilibrium of distinct lineage-specified progenitors ⬇️

scientific article published on January 1, 2012

Endoscopic molecular imaging of human bladder cancer using a CD47 antibody

scientific article

Enforced Bcl-2 expression overrides serum and feeder cell requirements for mouse embryonic stem cell self-renewal.

scientific article

Engagement of MHC class I by the inhibitory receptor LILRB1 suppresses macrophages and is a target of cancer immunotherapy.

scientific article published on 27 November 2017

Engineered SIRPα variants as immunotherapeutic adjuvants to anticancer antibodies

scientific article

Engineering high-affinity PD-1 variants for optimized immunotherapy and immuno-PET imaging

scientific article

Engraftment of sorted/expanded human central nervous system stem cells from fetal brain

scientific article published in September 2002

Enhanced survival of pluripotent stem cells under stressful conditions ⬇️

scientific article published on August 15, 2011

Epigenetic and in vivo comparison of diverse MSC sources reveals an endochondral signature for human hematopoietic niche formation

scientific article

Epigenetic characterization of hematopoietic stem cell differentiation using miniChIP and bisulfite sequencing analysis

scholarly article

Eradication of Canine Diffuse Large B-Cell Lymphoma in a Murine Xenograft Model with CD47 Blockade and Anti-CD20.

scientific article

Erratum: Human melanoma-initiating cells express neural crest nerve growth factor receptor CD271

scientific article published in Nature

Ethics. The ISSCR guidelines for human embryonic stem cell research

scientific article published on February 2007

Evaluation of the long-term reconstituting subset of hematopoietic stem cells with CD150

scientific article published on October 2009

Evidence that β7 Integrin Regulates Hematopoietic Stem Cell Homing and Engraftment Through Interaction with MAdCAM-1.

scientific article

Evolution of a protochordate allorecognition locus

scientific article published on 01 February 2004

Evolutionarily conserved resistance to phagocytosis observed in melanoma cells is insensitive to upregulation of pro-phagocytic signals and to CD47 blockade

scientific article published on 01 April 2020

Evolutionary perspective on the hematopoietic system through a colonial chordate: allogeneic immunity and hematopoiesis

scientific article published on 16 January 2020

Existing cardiomyocytes generate cardiomyocytes at a low rate after birth in mice

scientific article

Expression of AA4.1 marks lymphohematopoietic progenitors in early mouse development

scientific article published on 19 May 2009

Expression of BCR/ABL and BCL-2 in myeloid progenitors leads to myeloid leukemias

scientific article published on 30 July 2003

Expression of TCR-Vβ peptides by murine bone marrow cells does not identify T-cell progenitors

scientific article

Extranodal dissemination of non-Hodgkin lymphoma requires CD47 and is inhibited by anti-CD47 antibody therapy

scientific article

First-in-Human, First-in-Class Phase I Trial of the Anti-CD47 Antibody Hu5F9-G4 in Patients With Advanced Cancers

scientific article published on 27 February 2019

Flipping the script on macrophages in leiomyosarcoma

scientific article published on October 2012

Flk2+ common lymphoid progenitors possess equivalent differentiation potential for the B and T lineages

scientific article published on 18 April 2008

Flk2+ myeloid progenitors are the main source of Langerhans cells

scientific article published on November 2005

Flt3 ligand regulates dendritic cell development from Flt3+ lymphoid and myeloid-committed progenitors to Flt3+ dendritic cells in vivo

scientific article

Frequency of cells expressing CD44, a Head and Neck cancer stem cell marker: Correlation with tumor aggressiveness ⬇️

scientific article published on February 14, 2011

Frizzled 9 knock-out mice have abnormal B-cell development

scientific journal article

Functional and transcriptional characterization of human embryonic stem cell-derived endothelial cells for treatment of myocardial infarction

scientific article

Functionally distinct hematopoietic stem cells modulate hematopoietic lineage potential during aging by a mechanism of clonal expansion

scientific article

Gene Expression Commons: an open platform for absolute gene expression profiling

scientific article (publication date: 2012)

Gene expression analysis of purified hematopoietic stem cells and committed progenitors

scientific article published on 06 March 2003

Generation of a monoclonal antibody library against human embryonic stem cells

scientific article

Germ-layer and lineage-restricted stem/progenitors regenerate the mouse digit tip ⬇️

scientific article published on August 24, 2011

Global analysis of proliferation and cell cycle gene expression in the regulation of hematopoietic stem and progenitor cell fates

scientific article

Glycogen synthase kinase 3beta missplicing contributes to leukemia stem cell generation

scholarly article

HG-98IDENTIFICATION OF THE PRE-MALIGNANT CELL OF ORIGIN IN PEDIATRIC GLIOBLASTOMA MULTIFORME.

scientific article published on 30 May 2016

HIF-1α activation in myeloid cells accelerates dextran sodium sulfate-induced colitis progression in mice

scientific article published on 30 July 2018

Haematopoietic stem cells adopt mature haematopoietic fates in ischaemic myocardium

scientific article

Hedgehog-responsive candidate cell of origin for diffuse intrinsic pontine glioma

scientific article

Hematopoietic reconstitution by multipotent adult progenitor cells: precursors to long-term hematopoietic stem cells

scientific article

Hematopoietic reconstitution by multipotent adult progenitor cells: precursors to long-term hematopoietic stem cells.

scientific article

Hematopoietic stem and progenitor cells and the inflammatory response

scientific article

Hematopoietic stem and progenitor cells: clinical and preclinical regeneration of the hematolymphoid system

scientific article

Hematopoietic stem cell aging: mechanism and consequence.

scientific article

Hematopoietic stem cell and progenitor cell mechanisms in myelodysplastic syndromes ⬇️

scientific article published on February 6, 2013

Hematopoietic stem cell quiescence attenuates DNA damage response and permits DNA damage accumulation during aging.

scientific article

Hematopoietic stem cell quiescence is maintained by compound contributions of the retinoblastoma gene family

scientific article published on October 2008

Hematopoietic stem cell transplantation in immunocompetent hosts without radiation or chemotherapy.

scientific article published in August 2016

Hematopoietic stem cell-derived pericytic cells in brain tumor angio-architecture

scientific article published in February 2008

Hematopoietic stem cell: self-renewal versus differentiation

scientific article (publication date: April 2010)

Hematopoietic stem cells and the aging hematopoietic system

scientific article published on October 2008

Hematopoietic stem cells are uniquely selective in their migratory response to chemokines

scientific article

Hematopoietic stem cells: expression profiling and beyond

scientific article published on January 2006

Hematopoietic stem cells: the paradigmatic tissue-specific stem cell

scientific article published on August 2006

Heme oxygenase-1 deficiency leads to disrupted response to acute stress in stem cells and progenitors

scientific article published on 28 May 2008

Heme oxygenase-1 deficiency triggers exhaustion of hematopoietic stem cells

scientific article published on 29 December 2019

Hoxb5 defines the heterogeneity of self-renewal capacity in the hematopoietic stem cell compartment

scientific article published on 05 January 2021

Hoxb5 marks long-term haematopoietic stem cells and reveals a homogenous perivascular niche

scientific article published on February 2016

Human acute myelogenous leukemia stem cells revisited: there's more than meets the eye.

scientific article published on January 2011

Human bone marrow hematopoietic stem cells are increased in frequency and myeloid-biased with age ⬇️

scientific article published on November 28, 2011

Human melanoma-initiating cells express neural crest nerve growth factor receptor CD271

scientific article

Hypoxia-inducible factor-1α regulates microglial functions affecting neuronal survival in the acute phase of ischemic stroke in mice

scientific article published in December 2017

IL-1β-driven neutrophilia preserves antibacterial defense in the absence of the kinase IKKβ

scientific article published on 19 December 2010

IMMU-18. HUMANIZED ANTI-CD47 ANTIBODY COMBINED WITH AN AGONIST ANTI-CD40 ANTIBODY IS AN EFFECTIVE TREATMENT FOR DIPG XENOGRAFTS WITH CRANIOSPINAL DISSEMINATION.

scientific article

IMPS-26HARNESSING THE MYELOID CHECKPOINT CD47-SIRPa AXIS AGAINST ADULT AND PEDIATRIC MALIGNANT BRAIN TUMORS: A NOVEL IMMUNOTHERAPEUTIC MODALITY.

scientific article

Identification and characterization of an injury-induced skeletal progenitor

scientific article

Identification and prospective isolation of a mesothelial precursor lineage giving rise to smooth muscle cells and fibroblasts for mammalian internal organs, and their vasculature ⬇️

scientific article published on November 11, 2012

Identification and specification of the mouse skeletal stem cell

scientific article

Identification of a colonial chordate histocompatibility gene

scientific article

Identification of a hierarchy of multipotent hematopoietic progenitors in human cord blood

scientific article

Identification of human erythroid lineage-committed progenitors

scientific article published in May 2016

Identification of mast cell progenitors in adult mice

scientific article

Identification of mouse cochlear progenitors that develop hair and supporting cells in the organ of Corti

scientific article

Identification of multipotent progenitors that emerge prior to hematopoietic stem cells in embryonic development.

scientific article published on 20 March 2014

Identification of phagocytosis regulators using magnetic genome-wide CRISPR screens

scientific article published on 05 November 2018

Identification of phenotypic neural stem cells in a pediatric astroblastoma.

scientific article published in November 2005

Identification of the Human Skeletal Stem Cell

scientific article published on 01 September 2018

Identification of the earliest natural killer cell–committed progenitor in murine bone marrow ⬇️

scientific article published on September 19, 2011

Identification of the endostyle as a stem cell niche in a colonial chordate

scientific article

Identification of tumorigenic cells and therapeutic targets in pancreatic neuroendocrine tumors

scientific article published on 31 March 2016

Identification, molecular characterization, clinical prognosis, and therapeutic targeting of human bladder tumor-initiating cells

scientific article published on 18 August 2009

Imaging of STAT3 signaling pathway during mouse embryonic stem cell differentiation

scientific article

Immune Priming of the Tumor Microenvironment by Radiation

scientific article published on 15 October 2016

Immunogenicity of In Vitro Maintained and Matured Populations: Potential Barriers to Engraftment of Human Pluripotent Stem Cell Derivatives ⬇️

scientific article published on January 1, 2013

Immunotherapeutic Blockade of CD47 Inhibitory Signaling Enhances Innate and Adaptive Immune Responses to Viral Infection

scientific article published on 01 April 2020

Improving immune-vascular crosstalk for cancer immunotherapy.

scientific article published on 15 January 2018

Improving macrophage responses to therapeutic antibodies by molecular engineering of SIRPα variants

scientific article published on 29 July 2013

In utero depletion of fetal hematopoietic stem cells improves engraftment after neonatal transplantation in mice

scientific article

In vitro assays misrepresent in vivo lineage potentials of murine lymphoid progenitors ⬇️

scientific article published on December 16, 2010

In vivo clonal analysis reveals lineage-restricted progenitor characteristics in mammalian kidney development, maintenance, and regeneration.

scientific article published on 15 May 2014

In vivo directed differentiation of pluripotent stem cells for skeletal regeneration.

scientific article

In vivo evaluation of human hematopoiesis through xenotransplantation of purified hematopoietic stem cells from umbilical cord blood

scientific article published in January 2008

In vivo molecular MRI of cell survival and teratoma formation following embryonic stem cell transplantation into the injured murine myocardium

scientific article

In vivo serial evaluation of superparamagnetic iron-oxide labeled stem cells by off-resonance positive contrast

scientific article published on December 2008

In vivo visualization of embryonic stem cell survival, proliferation, and migration after cardiac delivery

scientific article

Incorporation of naive bone marrow derived cells into the vascular architecture of brain tumor

scientific article published in December 2004

Inhibition of Apoptosis Overcomes Stage-Related Compatibility Barriers to Chimera Formation in Mouse Embryos

scientific article published in November 2016

Innate immune cell activation causes lung fibrosis in a humanized model of long COVID

scientific article published in 2023

Insulin-like growth factor promotes engraftment, differentiation, and functional improvement after transfer of embryonic stem cells for myocardial restoration

scientific article published in January 2004

Irradiation or temozolomide chemotherapy enhances anti-CD47 treatment of glioblastoma

scientific article published on 23 September 2019

Isolation and characterization of a protochordate histocompatibility locus

scientific article published on November 2005

Isolation and functional assessment of mouse skeletal stem cell lineage

scientific article published on 10 May 2018

Isolation and mutational analysis of circulating tumor cells from lung cancer patients with magnetic sifters and biochips.

scientific article

Isolation of adult mouse myogenic progenitors: functional heterogeneity of cells within and engrafting skeletal muscle.

scientific article published in November 2004

Isolation of human fetal liver progenitors and their enhanced proliferation by three-dimensional coculture with endothelial cells

scientific article

Isolation of primitive endoderm, mesoderm, vascular endothelial and trophoblast progenitors from human pluripotent stem cells.

scientific article published on 27 May 2012

James L. Gowans 1924-2020

scientific article published on 01 June 2020

Janus-like opposing roles of CD47 in autoimmune brain inflammation in humans and mice

scientific article

JunB deficiency leads to a myeloproliferative disorder arising from hematopoietic stem cells

scientific article published in October 2004

LYVE1 Marks the Divergence of Yolk Sac Definitive Hemogenic Endothelium from the Primitive Erythroid Lineage.

scientific article published in November 2016

Langerhans cells renew in the skin throughout life under steady-state conditions

scientific article published on 4 November 2002

Learning from host-defense peptides: cationic, amphipathic peptoids with potent anticancer activity

scientific article

Lessons from immuno-oncology: a new era for cancer nanomedicine?

scientific article published on 17 March 2017

Leukemic transformation of hematopoietic progenitors by MLL-GAS7 in the absence of Hoxa7 or Hoxa9.

scientific article

Lift NIH restrictions on chimera research.

scientific article

Lineage infidelity in myeloid cells with TCR gene rearrangement: a latent developmental potential of proT cells revealed by ectopic cytokine receptor signaling

scientific article

Little evidence for developmental plasticity of adult hematopoietic stem cells

scientific article published on 5 September 2002

Live fibroblast harvest reveals surface marker shift in vitro

scientific article published on 17 December 2014

Localized hepatic lobular regeneration by central-vein-associated lineage-restricted progenitors

scientific article published on 22 March 2017

Long-term outcome of patients with metastatic breast cancer treated with high-dose chemotherapy and transplantation of purified autologous hematopoietic stem cells

scientific article

Ly6d marks the earliest stage of B-cell specification and identifies the branchpoint between B-cell and T-cell development

scientific journal article

MB-01NOTCH1 PROMOTES MYC MEDULLOBLASTOMA METASTASIS, INITIATION AND MAINTENANCE.

scientific article published on 21 April 2015

MB-16NOTCH1 PROMOTES GROUP 3 MEDULLOBLASTOMA METASTASIS, INITIATION AND SELF-RENEWAL.

scientific article published on 30 May 2016

MLL-GAS7 transforms multipotent hematopoietic progenitors and induces mixed lineage leukemias in mice

scientific article published on 01 February 2003

Macrophages are critical effectors of antibody therapies for cancer

scientific article

Macrophages as mediators of tumor immunosurveillance

scientific article published on 7 May 2010

Macrophages eat cancer cells using their own calreticulin as a guide: roles of TLR and Btk.

scientific article

Manganese-guided cellular MRI of human embryonic stem cell and human bone marrow stromal cell viability.

scientific article

Mapping the Pairwise Choices Leading from Pluripotency to Human Bone, Heart, and Other Mesoderm Cell Types

scientific article

Memory T and memory B cells share a transcriptional program of self-renewal with long-term hematopoietic stem cells

scholarly article

MiDReG: a method of mining developmentally regulated genes using Boolean implications

scientific article

MicroRNA-125b expands hematopoietic stem cells and enriches for the lymphoid-balanced and lymphoid-biased subsets ⬇️

scientific article published on November 30, 2010

Microglia are effector cells of CD47-SIRPα antiphagocytic axis disruption against glioblastoma

article published in the Proceedings of the National Academy of Sciences of the United States of America

Molecular Pathways: Activating T Cells after Cancer Cell Phagocytosis from Blockade of CD47 "Don't Eat Me" Signals

scientific article

Molecular imaging of embryonic stem cell misbehavior and suicide gene ablation.

scientific article published in January 2007

Molecular signatures of quiescent, mobilized and leukemia-initiating hematopoietic stem cells

scientific article

Multimodal evaluation of in vivo magnetic resonance imaging of myocardial restoration by mouse embryonic stem cells.

scientific article

Multimodality evaluation of the viability of stem cells delivered into different zones of myocardial infarction

scientific article published in July 2008

Myeloerythroid-restricted progenitors are sufficient to confer radioprotection and provide the majority of day 8 CFU-S.

scientific article

Myeloid Cell Origins, Differentiation, and Clinical Implications

scientific article published on October 2016

Myeloid or lymphoid promiscuity as a critical step in hematopoietic lineage commitment

scientific article published in July 2002

Myeloid progenitors protect against invasive aspergillosis and Pseudomonas aeruginosa infection following hematopoietic stem cell transplantation

scientific article published on 08 August 2002

Neogenin-1 distinguishes between myeloid-biased and balanced Hoxb5 + mouse long-term hematopoietic stem cells

scientific article published on 21 November 2019

Neural Placode Tissue Derived From Myelomeningocele Repair Serves as a Viable Source of Oligodendrocyte Progenitor Cells

scientific article published on 29 July 2015

Neural progenitor genes. Germinal zone expression and analysis of genetic overlap in stem cell populations

scientific article published on December 2003

Neuroprotection of host cells by human central nervous system stem cells in a mouse model of infantile neuronal ceroid lipofuscinosis

scientific article published in September 2009

Neutrophil and monocyte kinetics play critical roles in mouse peritoneal adhesion formation

scientific article published on 01 September 2019

New evidence supporting megakaryocyte-erythrocyte potential of flk2/flt3+ multipotent hematopoietic progenitors

scientific article

New tools for studying microglia in the mouse and human CNS.

scientific article published on 16 February 2016

Niche recycling through division-independent egress of hematopoietic stem cells

scientific article

Non-equivalence of Wnt and R-spondin ligands during Lgr5+ intestinal stem-cell self-renewal

scientific article

Normal and Neoplastic Stem Cells

scientific article published on 17 April 2017

Normal and leukemic hematopoiesis: Are leukemias a stem cell disorder or a reacquisition of stem cell characteristics? ⬇️

scientific article published on September 22, 2003

Notch1 regulates the initiation of metastasis and self-renewal of Group 3 medulloblastoma

scientific article published in Nature Communications

Novel hematopoietic progenitor populations revealed by direct assessment of GATA1 protein expression and cMPL signaling events

scientific article published on November 2011

Osteoclast derivation from mouse bone marrow

scientific article published on 6 November 2014

Over-expression of Bcl-2 provides protection in septic mice by a trans effect

scientific article published on 01 September 2003

Overexpression of BCL2 enhances survival of human embryonic stem cells during stress and obviates the requirement for serum factors.

scientific article

PD-1 expression by tumour-associated macrophages inhibits phagocytosis and tumour immunity.

scientific article

PM-08A HUMANIZED CO-TRANSPLANT XENOGRAFT MOUSE MODEL, TO STUDY TOXICITY OF DRUGS TARGETED AGAINST PEDIATRIC BRAIN TUMORS.

scientific article published on 21 April 2015

Parabiosis in mice: a detailed protocol

scientific article published on 06 October 2013

Partial Lobular Hepatectomy: A Surgical Model for Morphologic Liver Regeneration

scientific article published on 31 May 2018

Patients Beware: Commercialized Stem Cell Treatments on the Web

scientific article published on 17 June 2010

Pericytes are progenitors for coronary artery smooth muscle

scientific article published on 19 October 2015

Perturbation of the hematopoietic system during embryonic liver development due to disruption of polyubiquitin gene Ubc in mice.

scientific article

Phagocytosis checkpoints as new targets for cancer immunotherapy

scientific article published on 28 August 2019

Pharmacological rescue of diabetic skeletal stem cell niches.

scientific article

Pioneer factor interactions and unmethylated CpG dinucleotides mark silent tissue-specific enhancers in embryonic stem cells

scholarly article

Plasticity of adult stem cells

scientific article published on March 2004

Position-dependent silencing of germline Vß segments on TCRß alleles containing preassembled VßDJßCß1 genes

scientific article

Practical Immuno-PET Radiotracer Design Considerations for Human Immune Checkpoint Imaging.

scientific article published on 15 December 2016

Pre-Clinical Development of a Humanized Anti-CD47 Antibody with Anti-Cancer Therapeutic Potential

scientific article published on 21 September 2015

Preleukemic mutations in human acute myeloid leukemia affect epigenetic regulators and persist in remission

scientific article

Pro-efferocytic nanoparticles are specifically taken up by lesional macrophages and prevent atherosclerosis

scientific article published on 27 January 2020

Proefferocytic Therapy Promotes Transforming Growth Factor-β Signaling and Prevents Aneurysm Formation.

scientific article published in February 2018

Programmed cell removal by calreticulin in tissue homeostasis and cancer

scientific article published in Nature Communications

Programmed cell removal: a new obstacle in the road to developing cancer ⬇️

scientific article published on 08 December 2011

Prospective isolation of human clonogenic common myeloid progenitors

scientific article

Prospective isolation of human embryonic stem cell-derived cardiovascular progenitors that integrate into human fetal heart tissue

scientific article

Prospective isolation of human erythroid lineage-committed progenitors

scientific article

Prospective separation of normal and leukemic stem cells based on differential expression of TIM3, a human acute myeloid leukemia stem cell marker ⬇️

scientific article published on March 7, 2011

Proteomic analysis of young and old mouse hematopoietic stem cells and their progenitors reveals post-transcriptional regulation in stem cells

scientific article published on 25 November 2020

Pten, tumorigenesis, and stem cell self-renewal

scientific article published in April 2006

Publisher Correction: Notch1 regulates the initiation of metastasis and self-renewal of Group 3 medulloblastoma

scientific article published in Nature Communications

Purified hematopoietic stem cell engraftment of rare niches corrects severe lymphoid deficiencies without host conditioning

scientific article

Quiescent hematopoietic stem cells accumulate DNA damage during aging that is repaired upon entry into cell cycle

scientific article

RUNX3 levels in human hematopoietic progenitors are regulated by aging and dictate erythroid-myeloid balance

scientific article published on 06 June 2019

Rapid lymphocyte reconstitution of unconditioned immunodeficient mice with non-self-renewing multipotent hematopoietic progenitors.

scientific article published on June 2006

Reduced ribosomal protein gene dosage and p53 activation in low-risk myelodysplastic syndrome ⬇️

scientific article published on July 25, 2011

Reductive isolation from bone marrow and blood implicates common lymphoid progenitors as the major source of thymopoiesis

scientific article published on 16 October 2008

Regenerating the field of cardiovascular cell therapy

scientific article published on 18 February 2019

Remodeling of endogenous mammary epithelium by breast cancer stem cells

scientific article

Repeated, Long-Term Cycling of Putative Stem Cells between Niches in a Basal Chordate ⬇️

scientific article published on December 20, 2012

Reply to Soto-Pantoja et al. and Zhao et al.: Targeting CD47 on human solid tumors.

scientific article published on 24 August 2012

Restoring metabolism of myeloid cells reverses cognitive decline in ageing

scientific article published on 20 January 2021

Reversal of autoimmune disease in lupus-prone New Zealand black/New Zealand white mice by nonmyeloablative transplantation of purified allogeneic hematopoietic stem cells

scientific article published on 13 April 2007

SCNT-derived ESCs with mismatched mitochondria trigger an immune response in allogeneic hosts

scientific article published on 20 November 2014

SIRT1 acts as a nutrient-sensitive growth suppressor and its loss is associated with increased AMPK and telomerase activity

scientific article

Screening for genes that regulate the differentiation of human megakaryocytic lineage cells

article published in the Proceedings of the National Academy of Sciences of the United States of America

Self-renewal of the long-term reconstituting subset of hematopoietic stem cells is regulated by Ikaros.

scientific article

Shifting foci of hematopoiesis during reconstitution from single stem cells

scientific article

Similar MLL-associated leukemias arising from self-renewing stem cells and short-lived myeloid progenitors

scientific article

Simple and efficient isolation of hematopoietic stem cells from H2K-zFP transgenic mice

scientific article published on 9 August 2005

Single-cell analysis of early progenitor cells that build coronary arteries

scientific article published in Nature

Single-cell analysis reveals T cell infiltration in old neurogenic niches

scientific article published on 03 July 2019

Single-cell phospho-specific flow cytometric analysis demonstrates biochemical and functional heterogeneity in human hematopoietic stem and progenitor compartments.

scientific article

Skin fibrosis. Identification and isolation of a dermal lineage with intrinsic fibrogenic potential

scientific article

Sleep disruption impairs haematopoietic stem cell transplantation in mice

scientific article published on 14 October 2015

Space-time considerations for hematopoietic stem cell transplantation

scientific article published on August 2008

Stem cells are units of natural selection in a colonial ascidian

scientific article published in December 2005

Stem cells: Blood lines from embryo to adult

scientific article published in Nature

Stems cells and the pathways to aging and cancer

scientific article published on February 2008

Stepwise development of committed progenitors in the bone marrow that generate functional T cells in the absence of the thymus

scientific article

Stimulation of paracrine pathways with growth factors enhances embryonic stem cell engraftment and host-specific differentiation in the heart after ischemic myocardial injury

scientific article published on 9 May 2005

Striving for normality: whole body regeneration through a series of abnormal generations

scientific article published on 8 February 2007

Surface phenotype of Peyer's patch germinal center cells: implications for the role of germinal centers in B cell differentiation. 1982.

scientific article published in August 2005

Surgical adhesions in mice are derived from mesothelial cells and can be targeted by antibodies against mesothelial markers

scientific article published on 01 November 2018

Surgical debulking promotes recruitment of macrophages and triggers glioblastoma phagocytosis in combination with CD47 blocking immunotherapy

scientific article published on 06 January 2017

Surveillance of Stem Cell Fate and Function: A System for Assessing Cell Survival and Collagen Expression In Situ.

scientific article

Sustained in vitro intestinal epithelial culture within a Wnt-dependent stem cell niche

scientific article

Synthesis of a photocaged tamoxifen for light-dependent activation of Cre-ER recombinase-driven gene modification ⬇️

scientific article published on May 28, 2013

T-cell receptor-driven lymphomagenesis in mice derived from a reprogrammed T cell ⬇️

scientific article published on October 18, 2010

THE FATE OF BOTRYLLUS (ASCIDIACEA) LARVAE COSETTLED WITH PARENTAL COLONIES: BENEFICIAL OR DELETERIOUS CONSEQUENCES?

scientific article published in December 1987

TMIC-04. A POTENT MICROGLIAL RESPONSE TO BLOCKING THE CD47-SIRPα ANTI-PHAGOCYTIC AXIS OVERCOMES DEFICIENT MACROPHAGE RECRUITMENT DURING ANTI-CD47 IMMUNOTHERAPY AGAINST GLIOBLASTOMA

scientific article published on 6 November 2017

Targeting macrophage checkpoint inhibitor SIRPa for anticancer therapy

scientific article published on 19 May 2020

Telomerase activation and rejuvenation of telomere length in stimulated T cells derived from serially transplanted hematopoietic stem cells

scientific article

The CD47-SIRPα pathway in cancer immune evasion and potential therapeutic implications

scientific article

The CD47-signal regulatory protein alpha (SIRPa) interaction is a therapeutic target for human solid tumors

scientific article

The GABA receptor GABRR1 is expressed on and functional in hematopoietic stem cells and megakaryocyte progenitors

scientific article published on 26 August 2019

The JAK2 V617F mutation occurs in hematopoietic stem cells in polycythemia vera and predisposes toward erythroid differentiation

scholarly article

The Role of Efferocytosis in Atherosclerosis

scientific article

The adhesion molecule esam1 is a novel hematopoietic stem cell marker

scientific article

The effect of bleeding on hematopoietic stem cell cycling and self-renewal

scientific article published in October 2007

The genome sequence of the colonial chordate, Botryllus schlosseri

scientific article published in 2013

The origin and fate of yolk sac hematopoiesis: application of chimera analyses to developmental studies

scientific article published on January 2010

The origins of the identification and isolation of hematopoietic stem cells, and their capability to induce donor-specific transplantation tolerance and treat autoimmune diseases

scientific article published on November 2008

The road to purified hematopoietic stem cell transplants is paved with antibodies.

scientific article published on 29 August 2012

The safety of embryonic stem cell therapy relies on teratoma removal.

scientific article published on January 2012

Therapeutic Antibody Targeting of CD47 Eliminates Human Acute Lymphoblastic Leukemia ⬇️

scientific article published on December 21, 2010

Therapeutic Targeting of the Macrophage Immune Checkpoint CD47 in Myeloid Malignancies

scientific article published on 01 January 2019

They are not stealthy in the heart: embryonic stem cells trigger cell infiltration, humoral and T-lymphocyte-based host immune response.

scientific article published on September 2005

Three differentiation states risk-stratify bladder cancer into distinct subtypes

scientific article published on 19 January 2012

Tracking single hematopoietic stem cells in vivo using high-throughput sequencing in conjunction with viral genetic barcoding ⬇️

scientific article published on October 2, 2011

Transcription factor profiling in individual hematopoietic progenitors by digital RT-PCR

scholarly article

Transcriptional activation of hypoxia-inducible factor-1 (HIF-1) in myeloid cells promotes angiogenesis through VEGF and S100A8.

scientific article published on 04 February 2014

Transcriptional and functional profiling of human embryonic stem cell-derived cardiomyocytes

scientific article (publication date: 2008)

Transcriptional instability is not a universal attribute of aging.

scientific article published on 8 October 2007

Transcriptional profiling of antigen-dependent murine B cell differentiation and memory formation

scientific article published in November 2007

Tumor-Associated Macrophages Enhance Tumor Hypoxia and Aerobic Glycolysis

scientific article published on 04 January 2019

Tumorigenicity as a clinical hurdle for pluripotent stem cell therapies

scientific article published on 06 August 2013

Tuning cytokine receptor signaling by re-orienting dimer geometry with surrogate ligands

scientific article published on 26 February 2015

Two-step oligoclonal development of male germ cells

scholarly article

Unifying mechanism for different fibrotic diseases

scientific article published on 19 April 2017

Upregulation of CD11A on hematopoietic stem cells denotes the loss of long-term reconstitution potential

scientific article published on 16 October 2014

Upregulation of CD47 Is a Host Checkpoint Response to Pathogen Recognition

scientific article published on 23 June 2020

Use of a KIT-specific monoclonal antibody to bypass imatinib resistance in gastrointestinal stromal tumors

scientific article published on 14 May 2013

VHL loss in renal cell carcinoma leads to up-regulation of CUB domain-containing protein 1 to stimulate PKC{delta}-driven migration

scientific article

Varicella-zoster virus infection of human neural cells in vivo.

scholarly article

Where hematopoietic stem cells live - the bone marrow niche.

scientific article

Wounds Inhibit Tumor Growth In Vivo

scientific article published on 27 February 2019

fester, A candidate allorecognition receptor from a primitive chordate

scientific article published in July 2006

microRNA-29a induces aberrant self-renewal capacity in hematopoietic progenitors, biased myeloid development, and acute myeloid leukemia

scientific article

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