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List of works by Joseph P Noel

A Red Algal Bourbonane Sesquiterpene Synthase Defined by Microgram-Scale NMR-Coupled Crystalline Sponge X-ray Diffraction Analysis

scientific article published on 30 October 2017

A chemical, genetic, and structural analysis of the nuclear bile acid receptor FXR

scientific article (publication date: April 2003)

A coupled in vitro/in vivo approach for engineering a heterologous Type III PKS to enhance polyketide biosynthesis in Saccharomyces cerevisiae.

scientific article published on 19 February 2018

A single-vial analytical and quantitative gas chromatography-mass spectrometry assay for terpene synthases

scientific article

A soluble, magnesium-independent prenyltransferase catalyzes reverse and regular C-prenylations and O-prenylations of aromatic substrates

scientific article published on 22 May 2007

Absence of substrate channeling between active sites in the Agrobacterium tumefaciens IspDF and IspE enzymes of the methyl erythritol phosphate pathway

scientific article published on March 2006

Activity Mapping the Acyl Carrier Protein - Elongating Ketosynthase Interaction in Fatty Acid Biosynthesis

scientific article published on 28 August 2020

Algal neurotoxin biosynthesis repurposes the terpene cyclase structural fold into an N-prenyltransferase

scientific article published on 26 May 2020

An Arabidopsis thaliana gene for methylsalicylate biosynthesis, identified by a biochemical genomics approach, has a role in defense

scientific article published in December 2003

An Arabidopsis thaliana methyltransferase capable of methylating farnesoic acid

scientific article

An aldol switch discovered in stilbene synthases mediates cyclization specificity of type III polyketide synthases

scientific article published in September 2004

An enzyme-coupled colorimetric assay for S-adenosylmethionine-dependent methyltransferases

scientific article published in March 2004

Architectures, mechanisms and molecular evolution of natural product methyltransferases

scientific article

Author response

Biochemical and structural characterization of benzenoid carboxyl methyltransferases involved in floral scent production in Stephanotis floribunda and Nicotiana suaveolens

scientific article

Biosynthesis of Dictyostelium discoideum differentiation-inducing factor by a hybrid type I fatty acid-type III polyketide synthase

scientific article

Biosynthesis of coral settlement cue tetrabromopyrrole in marine bacteria by a uniquely adapted brominase-thioesterase enzyme pair

scientific article (publication date: 5 April 2016)

Biosynthesis of plant volatiles: nature's diversity and ingenuity

scientific article

Biosynthesis of t-anethole in anise: characterization of t-anol/isoeugenol synthase and an O-methyltransferase specific for a C7-C8 propenyl side chain

scientific article

Biosynthetic potential of sesquiterpene synthases: alternative products of tobacco 5-epi-aristolochene synthase

scientific article

Biosynthetic potential of sesquiterpene synthases: product profiles of Egyptian Henbane premnaspirodiene synthase and related mutants

scientific article

Bisabolyl-derived sesquiterpenes from tobacco 5-epi-aristolochene synthase-catalyzed cyclization of (2Z,6E)-farnesyl diphosphate

scientific article published in March 2010

Chapter Seven Properties and metabolic engineering of alfalfa phenylpropanoid pathway O-methyltransferases

Chapter two Structural, functional, and evolutionary basis for methylation of plant small molecules

article

Characterization of phenylpropene O-methyltransferases from sweet basil: facile change of substrate specificity and convergent evolution within a plant O-methyltransferase family

scientific article

Chemical biology: Synthetic metabolism goes green

scientific article published on November 2010

Chemodiversity in Selaginella: a reference system for parallel and convergent metabolic evolution in terrestrial plants

scientific article (publication date: 2013)

Chemoenzymatic syntheses of prenylated aromatic small molecules using Streptomyces prenyltransferases with relaxed substrate specificities

scientific article published on 24 July 2008

Cloning and expression of IspDF from Mesorhizobium loti. Characterization of a bifunctional protein that catalyzes non-consecutive steps in the methylerythritol phosphate pathway

scientific article

Co-evolution of Hormone Metabolism and Signaling Networks Expands Plant Adaptive Plasticity

scientific article

Confluence of structural and chemical biology: plant polyketide synthases as biocatalysts for a bio-based future.

scientific article published on 05 March 2013

Conformational flexibility underlies ubiquitin ligation mediated by the WWP1 HECT domain E3 ligase

scientific article

Contribution of isopentenyl phosphate to plant terpenoid metabolism

article

Coordination of auxin and ethylene biosynthesis by the aminotransferase VAS1.

scientific article published on 03 February 2013

Corrigendum to "Unveiling the functional diversity of the alpha/beta hydrolase superfamily in the plant kingdom" [Curr Opin Struct Biol 2016, 41:233-246].

scientific article published on 21 November 2016

Critical Role of WW Domain Phosphorylation in Regulating Phosphoserine Binding Activity and Pin1 Function ⬇️

scientific article published on November 26, 2001

Cryptochrome 1 interacts with PIF4 to regulate high temperature-mediated hypocotyl elongation in response to blue light

scientific article

Crystal structure of a bacterial type III polyketide synthase and enzymatic control of reactive polyketide intermediates

scientific journal article

Crystal structures of alfalfa caffeoyl coenzyme A 3-O-methyltransferase

scientific article published on 25 February 2005

Delusional disorder: an unusual presentation

scientific article published on October 2014

Determinants for Dephosphorylation of the RNA Polymerase II C-Terminal Domain by Scp1

scientific article

Digging for answers, smelling a hint of success and tasting triumph

scientific article published on November 2007

Discovery and characterization of a marine bacterial SAM-dependent chlorinase

scientific article

Discovery of Two Cyanobacterial Phenylalanine Ammonia Lyases:  Kinetic and Structural Characterization † , ‡

scientific article

Discovery of a metabolic alternative to the classical mevalonate pathway

scientific article published on 10 December 2013

Dissecting modular synthases through inhibition: A complementary chemical and genetic approach

scientific article published on 25 November 2019

Divergent perspectives on GM food

scientific article published on 01 December 2002

Dynamic Conformational States Dictate Selectivity toward the Native Substrate in a Substrate-Permissive Acyltransferase

scientific article published on 2 November 2016

Emergent Decarboxylase Activity and Attenuation of α/β-Hydrolase Activity during the Evolution of Methylketone Biosynthesis in Tomato ⬇️

scientific article published on April 20, 2012

Enzymatic functions of wild tomato methylketone synthases 1 and 2.

scientific article published on 6 July 2010

Eugenol and isoeugenol, characteristic aromatic constituents of spices, are biosynthesized via reduction of a coniferyl alcohol ester

scientific article

Evolution of chalcone isomerase from a non-catalytic ancestor

Evolution of chalcone isomerase from a noncatalytic ancestor

scientific article published on 23 April 2018

Evolution of the chalcone-isomerase fold from fatty-acid binding to stereospecific catalysis

scientific article

Evolving biosynthetic tangos negotiate mechanistic landscapes

scientific article published on April 2008

Expanding the biosynthetic repertoire of plant type III polyketide synthases by altering starter molecule specificity

scientific article

Expanding the library and substrate diversity of the pyrrolysyl-tRNA synthetase to incorporate unnatural amino acids containing conjugated rings

scientific article

Expression and characterization of the type III polyketide synthase 1,3,6,8-tetrahydroxynaphthalene synthase from Streptomyces coelicolor A3(2) ⬇️

scientific journal article

Flavin-mediated dual oxidation controls an enzymatic Favorskii-type rearrangement

scientific article

Floral benzenoid carboxyl methyltransferases: from in vitro to in planta function

scientific article

Formation of a Novel Macrocyclic Alkaloid from the Unnatural Farnesyl Diphosphate Analogue Anilinogeranyl Diphosphate by 5-Epi-Aristolochene Synthase

scientific article

Functional analyses of caffeic acid O-Methyltransferase and Cinnamoyl-CoA-reductase genes from perennial ryegrass (Lolium perenne).

scientific article published on 15 October 2010

Functional analysis of members of the isoflavone and isoflavanone O-methyltransferase enzyme families from the model legume Medicago truncatula.

scientific article

Functional characterization of premnaspirodiene oxygenase, a cytochrome P450 catalyzing regio- and stereo-specific hydroxylations of diverse sesquiterpene substrates

scientific article

Gating mechanism of elongating β-ketoacyl-ACP synthases

scientific article published on 07 April 2020

Gene library synthesis by structure-based combinatorial protein engineering.

scientific article published in January 2004

Genetic basis for the biosynthesis of the pharmaceutically important class of epoxyketone proteasome inhibitors.

scientific article

Genetically Encoding Unnatural Amino Acids in Neural Stem Cells and Optically Reporting Voltage-Sensitive Domain Changes in Differentiated Neurons ⬇️

scientific article published on August 1, 2011

Genetically encoding photoswitchable click amino acids in Escherichia coli and mammalian cells

scientific article

Genetically encoding unnatural amino acids for cellular and neuronal studies

scientific article

Harvesting the biosynthetic machineries that cultivate a variety of indispensable plant natural products

scientific article

Identification of a 3-aminoimidazo[1,2-a]pyridine inhibitor of HIV-1 reverse transcriptase

scientific article

Identifying and manipulating structural determinates linking catalytic specificities in terpene synthases

scholarly article

Interception of the enzymatic conversion of farnesyl diphosphate to 5-epi-aristolochene by using a fluoro substrate analogue: 1-fluorogermacrene A from (2E,6Z)-6-fluorofarnesyl diphosphate.

scientific article published on October 2007

Interfacial plasticity facilitates high reaction rate of E. coli FAS malonyl-CoA:ACP transacylase, FabD

scientific article published on 14 September 2020

Kinetic analysis of Escherichia coli 2-C-methyl-D-erythritol-4-phosphate cytidyltransferase, wild type and mutants, reveals roles of active site amino acids

scientific article published in September 2004

Kinetic and molecular analysis of 5-epiaristolochene 1,3-dihydroxylase, a cytochrome P450 enzyme catalyzing successive hydroxylations of sesquiterpenes

scientific article

Laetirobin from the Parasitic Growth ofLaetiporus sulphureusonRobinia pseudoacacia

article

Local auxin metabolism regulates environment-induced hypocotyl elongation

scientific article published on 21 March 2016

Mechanism-Based Post-Translational Modification and Inactivation in Terpene Synthases

scientific article

Mechanism-based cross-linking probes capture the <i>Escherichia coli</i> ketosynthase FabB in conformationally distinct catalytic states

scientific article published in 2022

Metabolic engineering of sesquiterpene metabolism in yeast

scientific article

Metabolite induction of Caenorhabditis elegans dauer larvae arises via transport in the pharynx

scientific article published on April 2008

Methylation of gibberellins by Arabidopsis GAMT1 and GAMT2

scientific article

Methylation of sulfhydryl groups: a new function for a family of small molecule plant O-methyltransferases

scientific article

Modulation of auxin formation by the cytosolic phenylalanine biosynthetic pathway

scientific article published on 13 April 2020

Molecular architectures of benzoic acid-specific type III polyketide synthases

scientific article published on 30 November 2017

Multiple biochemical and morphological factors underlie the production of methylketones in tomato trichomes

scientific article published on 2 October 2009

Mutation of Archaeal Isopentenyl Phosphate Kinase Highlights Mechanism and Guides Phosphorylation of Additional Isoprenoid Monophosphates

scientific article

New auxin analogs with growth-promoting effects in intact plants reveal a chemical strategy to improve hormone delivery

scholarly article

Orthologs of the archaeal isopentenyl phosphate kinase regulate terpenoid production in plants

scientific article

Physical Constraints on Sesquiterpene Diversity Arising from Cyclization of the Eudesm-5-yl Carbocation ⬇️

scientific article published on July 26, 2011

Plant-like biosynthetic pathways in bacteria: from benzoic acid to chalcone

scientific article

Publisher Correction: Evolution of chalcone isomerase from a noncatalytic ancestor

scientific article published on 01 October 2018

Quantitative exploration of the catalytic landscape separating divergent plant sesquiterpene synthases

scientific article

Rapid Synthesis of Auxin via a New Tryptophan-Dependent Pathway Is Required for Shade Avoidance in Plants

scientific article

Reaction mechanism of chalcone isomerase. pH dependence, diffusion control, and product binding differences

scientific article

Role of hydrogen bonds in the reaction mechanism of chalcone isomerase

scientific article

S-Adenosyl-L-methionine hydrolase (adenosine-forming), a conserved bacterial and archaeal protein related to SAM-dependent halogenases.

scientific article published on September 2008

Smoke-derived karrikin perception by the α/β-hydrolase KAI2 from Arabidopsis ⬇️

scientific article published on April 23, 2013

Spectral and structural comparison between bright and dim green fluorescent proteins in Amphioxus

scientific article published on 27 June 2014

Stereochemical Basis for Engineered Pyrrolysyl-tRNA Synthetase and the Efficient in Vivo Incorporation of Structurally Divergent Non-native Amino Acids

scientific article

Stereochemistry and deuterium isotope effects associated with the cyclization-rearrangements catalyzed by tobacco epiaristolochene and hyoscyamus premnaspirodiene synthases, and the chimeric CH4 hybrid cyclase

scientific article

Strigolactone perception and deactivation by a hydrolase receptor DWARF14

scientific article published in Nature Communications

Structural Basis for Dual Functionality of Isoflavonoid O-Methyltransferases in the Evolution of Plant Defense Responses

scientific article

Structural Basis for High-Affinity Peptide Inhibition of Human Pin1

scientific article

Structural Basis for Substrate Recognition in the Salicylic Acid Carboxyl Methyltransferase Family

scientific article

Structural Basis for the Modulation of Lignin Monomer Methylation by Caffeic Acid/5-Hydroxyferulic Acid 3/5-O-Methyltransferase

scientific article

Structural Determinants and Modulation of Substrate Specificity in Phenylalanine-Tyrosine Ammonia-Lyases

scientific article

Structural Elucidation of Cisoid and Transoid Cyclization Pathways of a Sesquiterpene Synthase Using 2-Fluorofarnesyl Diphosphates

scientific article published on 16 April 2010

Structural and Kinetic Analysis of Prolyl-isomerization/Phosphorylation Cross-Talk in the CTD Code

scientific article

Structural and functional analysis of the phosphoryl transfer reaction mediated by the human small C-terminal domain phosphatase, Scp1

scientific article

Structural and kinetic basis for substrate selectivity in Populus tremuloides sinapyl alcohol dehydrogenase

scientific article

Structural basis for specific ligation of the peroxisome proliferator-activated receptor δ.

scientific article published on 20 March 2017

Structural basis for the design of potent and species-specific inhibitors of 3-hydroxy-3-methylglutaryl CoA synthases

scholarly article

Structural basis for the modulation of CDK-dependent/independent activity of cyclin D1.

scientific article

Structural basis for the promiscuous biosynthetic prenylation of aromatic natural products

scientific article

Structural basis of steroid hormone perception by the receptor kinase BRI1

scientific article

Structural elucidation of chalcone reductase and implications for deoxychalcone biosynthesis.

scientific article

Structural studies of cinnamoyl-CoA reductase and cinnamyl-alcohol dehydrogenase, key enzymes of monolignol biosynthesis.

scientific article

Structural, Biochemical, and Phylogenetic Analyses Suggest That Indole-3-Acetic Acid Methyltransferase Is an Evolutionarily Ancient Member of the SABATH Family

scientific article

Structure and mechanism of 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase. An enzyme in the mevalonate-independent isoprenoid biosynthetic pathway

scientific article

Structure and reaction mechanism of basil eugenol synthase

scientific article

Structure of the Mg-chelatase cofactor GUN4 reveals a novel hand-shaped fold for porphyrin binding

scientific article

Structure, Biochemistry, and Inhibition of Essential 4′-Phosphopantetheinyl Transferases from Two Species of Mycobacteria

scientific article

Structure-Function Analyses of a Caffeic Acid O-Methyltransferase from Perennial Ryegrass Reveal the Molecular Basis for Substrate Preference ⬇️

scientific article published on December 21, 2010

Structure-function relationships in plant phenylpropanoid biosynthesis

scientific article (publication date: June 2005)

Structure-function-folding relationship in a WW domain

scientific article

Structure–Function Analyses of Plant Type III Polyketide Synthases

scientific article published on January 1, 2012

Substrate Specificity and Engineering of Mevalonate 5-Phosphate Decarboxylase

scientific article published on 17 July 2019

The chalcone synthase superfamily of type III polyketide synthases

scientific article (publication date: February 2003)

The lack of floral synthesis and emission of isoeugenol in Petunia axillaris subsp. parodii is due to a mutation in the isoeugenol synthase gene

scientific article

The multiple phenylpropene synthases in both Clarkia breweri and Petunia hybrida represent two distinct protein lineages

scientific article

The phosphopantetheinyl transferases: catalysis of a post-translational modification crucial for life

scientific article (publication date: 2014)

The rise of chemodiversity in plants

scientific article

The structure of the membrane distal phosphatase domain of RPTPalpha reveals interdomain flexibility and an SH2 domain interaction region

scientific article

Type III polyketide synthase beta-ketoacyl-ACP starter unit and ethylmalonyl-CoA extender unit selectivity discovered by Streptomyces coelicolor genome mining ⬇️

scientific article published on November 2006

Unveiling the functional diversity of the alpha/beta hydrolase superfamily in the plant kingdom

scientific article published on 20 September 2016

[Structure of the Mg-chelatase cofactor GUN4 reveals a novel hand-shaped fold for porphyrin binding]

scientific article published on 01 November 2005

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