List of works - Gye Won Han

5-HT2C Receptor Structures Reveal the Structural Basis of GPCR Polypharmacology.

scientific article published on 19 January 2018

A Structural Basis for the Regulatory Inactivation of DnaA

scientific article

A conserved fold for fimbrial components revealed by the crystal structure of a putative fimbrial assembly protein (BT1062) from Bacteroides thetaiotaomicron at 2.2 Å resolution

scientific article

Agonist-bound structure of the human P2Y12 receptor

scientific article

Allosteric Coupling of Drug Binding and Intracellular Signaling in the A2A Adenosine Receptor

scientific article published on 27 December 2017

Bacterial Pleckstrin Homology Domains: A Prokaryotic Origin for the PH Domain

scientific article

Comparative structural analysis of a novel glutathioneS-transferase (ATU5508) from Agrobacterium tumefaciens at 2.0 A resolution

scientific article published in November 2006

Conformational changes associated with the binding of zinc acetate at the putative active site of Xc TcmJ, a cupin from Xanthomonas campestris pv. campestris

scientific article

Crystal Structure of Histidine Phosphotransfer Protein ShpA, an Essential Regulator of Stalk Biogenesis in Caulobacter crescentus

scientific article

Crystal Structure of a Lipid G Protein–Coupled Receptor ⬇️

scientific article published on February 17, 2012

Crystal Structure of the First Eubacterial Mre11 Nuclease Reveals Novel Features that May Discriminate Substrates During DNA Repair

scientific article

Crystal structure of AICAR transformylase IMP cyclohydrolase (TM1249) from Thermotoga maritima at 1.88 A resolution

scientific article

Crystal structure of Hsp33 chaperone (TM1394) from Thermotoga maritima at 2.20 Å resolution

article

Crystal structure of MtnX phosphatase from Bacillus subtilis at 2.0 angstroms resolution provides a structural basis for bipartite phosphomonoester hydrolysis of 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate

scientific article

Crystal structure of NMA1982 from Neisseria meningitidis at 1.5 angstroms resolution provides a structural scaffold for nonclassical, eukaryotic-like phosphatases

scientific article

Crystal structure of S-adenosylmethionine:tRNA ribosyltransferase-isomerase (QueA) from Thermotoga maritima at 2.0 A resolution reveals a new fold

scientific article

Crystal structure of TM1030 from Thermotoga maritima at 2.3 A resolution reveals molecular details of its transcription repressor function

scientific article published in July 2007

Crystal structure of TM1367 from Thermotoga maritima at 1.90 A resolution reveals an atypical member of the cyclophilin (peptidylprolyl isomerase) fold

scientific article published in June 2006

Crystal structure of a conserved hypothetical protein (gi: 13879369) from Mouse at 1.90 Å resolution reveals a new fold

article

Crystal structure of a metal-dependent phosphoesterase (YP_910028.1) from Bifidobacterium adolescentis: Computational prediction and experimental validation of phosphoesterase activity

scientific article

Crystal structure of a multi-domain human smoothened receptor in complex with a super stabilizing ligand

scientific article

Crystal structure of a novel Sm-like protein of putative cyanophage origin at 2.60 Å resolution

scientific article

Crystal structure of a novel archaeal AAA+ ATPase SSO1545 fromSulfolobus solfataricus

scientific article

Crystal structure of a putative modulator of DNA gyrase (pmbA) from Thermotoga maritima at 1.95 A resolution reveals a new fold

scientific article

Crystal structure of acireductone dioxygenase (ARD) from Mus musculus at 2.06 angstrom resolution

scientific article

Crystal structure of an ADP-ribosylated protein with a cytidine deaminase-like fold, but unknown function (TM1506), from Thermotoga maritima at 2.70 A resolution

scientific article

Crystal structure of an Apo mRNA decapping enzyme (DcpS) from Mouse at 1.83 A resolution

scientific article

Crystal structure of an ORFan protein (TM1622) fromThermotoga maritimaat 1.75 Å resolution reveals a fold similar to the Ran-binding protein Mog1p

article

Crystal structure of an alanine-glyoxylate aminotransferase from Anabaena sp. at 1.70 A resolution reveals a noncovalently linked PLP cofactor

scientific article published in March 2005

Crystal structure of an alpha/beta serine hydrolase (YDR428C) from Saccharomyces cerevisiae at 1.85 A resolution

scientific article

Crystal structure of an indigoidine synthase A (IndA)-like protein (TM1464) from Thermotoga maritima at 1.90 Å resolution reveals a new fold

article

Crystal structure of homoserine O-succinyltransferase from Bacillus cereus at 2.4 A resolution

scientific article

Crystal structure of misoprostol bound to the labor inducer prostaglandin E2 receptor

scientific article published on 03 December 2018

Crystal structure of phosphoribosylformylglycinamidine synthase II (smPurL) from Thermotoga maritima at 2.15 A resolution

scientific article

Crystal structure of rhodopsin bound to arrestin by femtosecond X-ray laser

scientific article

Crystal structure of the ApbE protein (TM1553) from Thermotoga maritima at 1.58 Å resolution

article

Crystal structure of the Fic (Filamentation induced by cAMP) family protein SO4266 (gi|24375750) from Shewanella oneidensis MR-1 at 1.6 Å resolution

scientific article

Crystal structure of the global regulatory protein CsrA from Pseudomonas putida at 2.05 A resolution reveals a new fold

scientific article published in November 2005

Crystal structure of virulence factor CJ0248 from Campylobacter jejuni at 2.25 A resolution reveals a new fold

scientific article

Crystal structures of MW1337R and lin2004: representatives of a novel protein family that adopt a four-helical bundle fold

scientific article

Crystal structures of agonist-bound human cannabinoid receptor CB1.

scientific article published on 05 July 2017

Crystal structures of two novel dye-decolorizing peroxidases reveal a beta-barrel fold with a conserved heme-binding motif

scientific article

Determination of the melanocortin-4 receptor structure identifies Ca2+ as a cofactor for ligand binding

scientific article published on 01 April 2020

Elucidating the active δ-opioid receptor crystal structure with peptide and small-molecule agonists

scientific article published on 27 November 2019

Functional and structural characterization of a thermostable acetyl esterase from Thermotoga maritima

scientific article

Harnessing the power of an X-ray laser for serial crystallography of membrane proteins crystallized in lipidic cubic phase

scientific article published on 15 October 2020

Human GLP-1 receptor transmembrane domain structure in complex with allosteric modulators

scientific article

Identification and structural characterization of heme binding in a novel dye-decolorizing peroxidase, TyrA

scientific article

Lipidic cubic phase injector facilitates membrane protein serial femtosecond crystallography

scientific article

Native phasing of x-ray free-electron laser data for a G protein-coupled receptor.

scientific article

Open and closed conformations of two SpoIIAA-like proteins (YP_749275.1 and YP_001095227.1) provide insights into membrane association and ligand binding

scientific article

Publisher Correction: Crystal structure of misoprostol bound to the labor inducer prostaglandin E2 receptor

scientific article published on 01 February 2019

Serial Femtosecond Crystallography of G Protein-Coupled Receptors

scientific article

Structural Basis for Allosteric Regulation of GPCRs by Sodium Ions

scientific article

Structural Basis for Apelin Control of the Human Apelin Receptor

scientific article published on 11 May 2017

Structural Basis for Ligand Recognition and Functional Selectivity at Angiotensin Receptor

scientific article

Structural Basis for Molecular Recognition at Serotonin Receptors

scientific article

Structural Basis of Murein Peptide Specificity of a γ-D-Glutamyl-L-Diamino Acid Endopeptidase

scientific article

Structural Connection between Activation Microswitch and Allosteric Sodium Site in GPCR Signaling

scientific article published on 26 January 2018

Structural Features for Functional Selectivity at Serotonin Receptors

scientific article

Structural and functional characterizations of SsgB, a conserved activator of developmental cell division in morphologically complex actinomycetes

scientific article

Structural basis for Smoothened receptor modulation and chemoresistance to anticancer drugs

scientific article

Structural basis for bifunctional peptide recognition at human δ-opioid receptor

scientific article

Structural basis for selectivity and diversity in angiotensin II receptors

scientific article

Structural basis of ligand recognition at the human MT1 melatonin receptor

scientific article published on 24 April 2019

Structural basis of ligand selectivity and disease mutations in cysteinyl leukotriene receptors

scientific article published on 06 December 2019

Structural basis of the activation of a metabotropic GABA receptor

scientific article published on 17 June 2020

Structural insights into the extracellular recognition of the human serotonin 2B receptor by an antibody

scientific article published on 17 July 2017

Structural insights on ligand recognition at the human leukotriene B4 receptor 1

scientific article published on 20 May 2021

Structure of BT_3984, a member of the SusD/RagB family of nutrient-binding molecules

scientific article

Structure of Bacteroides thetaiotaomicron BT2081 at 2.05 Å resolution: the first structural representative of a new protein family that may play a role in carbohydrate metabolism

scientific article

Structure of LP2179, the first representative of Pfam family PF08866, suggests a new fold with a role in amino-acid metabolism

scientific article

Structure of a class C GPCR metabotropic glutamate receptor 1 bound to an allosteric modulator

scientific article

Structure of a membrane-attack complex/perforin (MACPF) family protein from the human gut symbiont Bacteroides thetaiotaomicron

scientific article

Structure of a putative NTP pyrophosphohydrolase: YP_001813558.1 from Exiguobacterium sibiricum 255-15

scientific article

Structure of a tryptophanyl-tRNA synthetase containing an iron–sulfur cluster

scientific article

Structure of an agonist-bound human A2A adenosine receptor

scientific article

Structure of an essential bacterial protein YeaZ (TM0874) from Thermotoga maritima at 2.5 Å resolution

scientific article

Structure of the Angiotensin receptor revealed by serial femtosecond crystallography.

scientific article published on 23 April 2015

Structure of the CCR5 Chemokine Receptor-HIV Entry Inhibitor Maraviroc Complex

scientific article

Structure of the Human Dopamine D3 Receptor in Complex with a D2/D3 Selective Antagonist

scientific article

Structure of the Nanobody-Stabilized Active State of the Kappa Opioid Receptor.

scientific article published on 3 January 2018

Structure of the first representative of Pfam family PF04016 (DUF364) reveals enolase and Rossmann-like folds that combine to form a unique active site with a possible role in heavy-metal chelation

scientific article

Structure of the first representative of Pfam family PF09410 (DUF2006) reveals a structural signature of the calycin superfamily that suggests a role in lipid metabolism

scientific article

Structure of the human P2Y12 receptor in complex with an antithrombotic drug

scientific article

Structure of the human glucagon class B G-protein-coupled receptor

scientific article

Structure of the human histamine H1 receptor complex with doxepin

scientific article

Structure of the human smoothened receptor bound to an antitumour agent

scientific article

Structure of the human κ-opioid receptor in complex with JDTic

scientific article

Structure of the γ- D -glutamyl- L -diamino acid endopeptidase YkfC from Bacillus cereus in complex with L -Ala-γ- D -Glu: insights into substrate recognition by NlpC/P60 cysteine peptidases

scientific article

Structure-based mechanism of cysteinyl leukotriene receptor inhibition by antiasthmatic drugs

scientific article published on 09 October 2019

Structures of the first representatives of Pfam family PF06684 (DUF1185) reveal a novel variant of the Bacillus chorismate mutase fold and suggest a role in amino-acid metabolism

scientific article

Structures of the first representatives of Pfam family PF06938 (DUF1285) reveal a new fold with repeated structural motifs and possible involvement in signal transduction

scientific article

Structures of three members of Pfam PF02663 (FmdE) implicated in microbial methanogenesis reveal a conserved α+β core domain and an auxiliary C-terminal treble-clef zinc finger

scientific article

The crystal structure of a bacterial Sufu-like protein defines a novel group of bacterial proteins that are similar to the N-terminal domain of human Sufu

scientific article

The role of a sodium ion binding site in the allosteric modulation of the A(2A) adenosine G protein-coupled receptor

scientific article

The structure of BVU2987 from Bacteroides vulgatus reveals a superfamily of bacterial periplasmic proteins with possible inhibitory function

scientific article

The structure of Haemophilus influenzae prephenate dehydrogenase suggests unique features of bifunctional TyrA enzymes

scientific article

The structure of Jann_2411 (DUF1470) from Jannaschia sp. at 1.45 Å resolution reveals a new fold (the ABATE domain) and suggests its possible role as a transcription regulator

scientific article

The structure of KPN03535 (gi|152972051), a novel putative lipoprotein from Klebsiella pneumoniae , reveals an OB-fold

scientific article

The structure of SSO2064, the first representative of Pfam family PF01796, reveals a novel two-domain zinc-ribbon OB-fold architecture with a potential acyl-CoA-binding role

scientific article

The structure of the first representative of Pfam family PF06475 reveals a new fold with possible involvement in glycolipid metabolism

scientific article

The structure of the first representative of Pfam family PF09836 reveals a two-domain organization and suggests involvement in transcriptional regulation

scientific article

Toward G protein-coupled receptor structure-based drug design using X-ray lasers

scientific article published on 24 October 2019

Two disparate ligand-binding sites in the human P2Y1 receptor

scientific article

X-ray laser diffraction for structure determination of the rhodopsin-arrestin complex

scientific article

XFEL structures of the human MT2 melatonin receptor reveal the basis of subtype selectivity

scientific article published on 24 April 2019

List of works by Gye Won Han

5-HT2C Receptor Structures Reveal the Structural Basis of GPCR Polypharmacology.

A Structural Basis for the Regulatory Inactivation of DnaA

A conserved fold for fimbrial components revealed by the crystal structure of a putative fimbrial assembly protein (BT1062) from Bacteroides thetaiotaomicron at 2.2 Å resolution

Agonist-bound structure of the human P2Y12 receptor

Allosteric Coupling of Drug Binding and Intracellular Signaling in the A2A Adenosine Receptor

Bacterial Pleckstrin Homology Domains: A Prokaryotic Origin for the PH Domain

Comparative structural analysis of a novel glutathioneS-transferase (ATU5508) from Agrobacterium tumefaciens at 2.0 A resolution

Conformational changes associated with the binding of zinc acetate at the putative active site of Xc TcmJ, a cupin from Xanthomonas campestris pv. campestris

Crystal Structure of Histidine Phosphotransfer Protein ShpA, an Essential Regulator of Stalk Biogenesis in Caulobacter crescentus

Crystal Structure of a Lipid G Protein–Coupled Receptor ⬇️

Crystal Structure of the First Eubacterial Mre11 Nuclease Reveals Novel Features that May Discriminate Substrates During DNA Repair

Crystal structure of AICAR transformylase IMP cyclohydrolase (TM1249) from Thermotoga maritima at 1.88 A resolution

Crystal structure of Hsp33 chaperone (TM1394) from Thermotoga maritima at 2.20 Å resolution

Crystal structure of MtnX phosphatase from Bacillus subtilis at 2.0 angstroms resolution provides a structural basis for bipartite phosphomonoester hydrolysis of 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate

Crystal structure of NMA1982 from Neisseria meningitidis at 1.5 angstroms resolution provides a structural scaffold for nonclassical, eukaryotic-like phosphatases

Crystal structure of S-adenosylmethionine:tRNA ribosyltransferase-isomerase (QueA) from Thermotoga maritima at 2.0 A resolution reveals a new fold

Crystal structure of TM1030 from Thermotoga maritima at 2.3 A resolution reveals molecular details of its transcription repressor function

Crystal structure of TM1367 from Thermotoga maritima at 1.90 A resolution reveals an atypical member of the cyclophilin (peptidylprolyl isomerase) fold

Crystal structure of a conserved hypothetical protein (gi: 13879369) from Mouse at 1.90 Å resolution reveals a new fold

Crystal structure of a metal-dependent phosphoesterase (YP_910028.1) from Bifidobacterium adolescentis: Computational prediction and experimental validation of phosphoesterase activity

Crystal structure of a multi-domain human smoothened receptor in complex with a super stabilizing ligand

Crystal structure of a novel Sm-like protein of putative cyanophage origin at 2.60 Å resolution

Crystal structure of a novel archaeal AAA+ ATPase SSO1545 fromSulfolobus solfataricus

Crystal structure of a putative modulator of DNA gyrase (pmbA) from Thermotoga maritima at 1.95 A resolution reveals a new fold

Crystal structure of acireductone dioxygenase (ARD) from Mus musculus at 2.06 angstrom resolution

Crystal structure of an ADP-ribosylated protein with a cytidine deaminase-like fold, but unknown function (TM1506), from Thermotoga maritima at 2.70 A resolution

Crystal structure of an Apo mRNA decapping enzyme (DcpS) from Mouse at 1.83 A resolution

Crystal structure of an ORFan protein (TM1622) fromThermotoga maritimaat 1.75 Å resolution reveals a fold similar to the Ran-binding protein Mog1p

Crystal structure of an alanine-glyoxylate aminotransferase from Anabaena sp. at 1.70 A resolution reveals a noncovalently linked PLP cofactor

Crystal structure of an alpha/beta serine hydrolase (YDR428C) from Saccharomyces cerevisiae at 1.85 A resolution

Crystal structure of an indigoidine synthase A (IndA)-like protein (TM1464) from Thermotoga maritima at 1.90 Å resolution reveals a new fold

Crystal structure of homoserine O-succinyltransferase from Bacillus cereus at 2.4 A resolution

Crystal structure of misoprostol bound to the labor inducer prostaglandin E2 receptor

Crystal structure of phosphoribosylformylglycinamidine synthase II (smPurL) from Thermotoga maritima at 2.15 A resolution

Crystal structure of rhodopsin bound to arrestin by femtosecond X-ray laser

Crystal structure of the ApbE protein (TM1553) from Thermotoga maritima at 1.58 Å resolution

Crystal structure of the Fic (Filamentation induced by cAMP) family protein SO4266 (gi|24375750) from Shewanella oneidensis MR-1 at 1.6 Å resolution

Crystal structure of the global regulatory protein CsrA from Pseudomonas putida at 2.05 A resolution reveals a new fold

Crystal structure of virulence factor CJ0248 from Campylobacter jejuni at 2.25 A resolution reveals a new fold

Crystal structures of MW1337R and lin2004: representatives of a novel protein family that adopt a four-helical bundle fold

Crystal structures of agonist-bound human cannabinoid receptor CB1.

Crystal structures of two novel dye-decolorizing peroxidases reveal a beta-barrel fold with a conserved heme-binding motif

Determination of the melanocortin-4 receptor structure identifies Ca2+ as a cofactor for ligand binding

Elucidating the active δ-opioid receptor crystal structure with peptide and small-molecule agonists

Functional and structural characterization of a thermostable acetyl esterase from Thermotoga maritima

Harnessing the power of an X-ray laser for serial crystallography of membrane proteins crystallized in lipidic cubic phase

Human GLP-1 receptor transmembrane domain structure in complex with allosteric modulators

Identification and structural characterization of heme binding in a novel dye-decolorizing peroxidase, TyrA

Lipidic cubic phase injector facilitates membrane protein serial femtosecond crystallography

Native phasing of x-ray free-electron laser data for a G protein-coupled receptor.

Open and closed conformations of two SpoIIAA-like proteins (YP_749275.1 and YP_001095227.1) provide insights into membrane association and ligand binding

Publisher Correction: Crystal structure of misoprostol bound to the labor inducer prostaglandin E2 receptor

Serial Femtosecond Crystallography of G Protein-Coupled Receptors

Structural Basis for Allosteric Regulation of GPCRs by Sodium Ions

Structural Basis for Apelin Control of the Human Apelin Receptor

Structural Basis for Ligand Recognition and Functional Selectivity at Angiotensin Receptor

Structural Basis for Molecular Recognition at Serotonin Receptors

Structural Basis of Murein Peptide Specificity of a γ-D-Glutamyl-L-Diamino Acid Endopeptidase

Structural Connection between Activation Microswitch and Allosteric Sodium Site in GPCR Signaling

Structural Features for Functional Selectivity at Serotonin Receptors

Structural and functional characterizations of SsgB, a conserved activator of developmental cell division in morphologically complex actinomycetes

Structural basis for Smoothened receptor modulation and chemoresistance to anticancer drugs

Structural basis for bifunctional peptide recognition at human δ-opioid receptor

Structural basis for selectivity and diversity in angiotensin II receptors

Structural basis of ligand recognition at the human MT1 melatonin receptor

Structural basis of ligand selectivity and disease mutations in cysteinyl leukotriene receptors

Structural basis of the activation of a metabotropic GABA receptor

Structural insights into the extracellular recognition of the human serotonin 2B receptor by an antibody

Structural insights on ligand recognition at the human leukotriene B4 receptor 1

Structure of BT_3984, a member of the SusD/RagB family of nutrient-binding molecules

Structure of Bacteroides thetaiotaomicron BT2081 at 2.05 Å resolution: the first structural representative of a new protein family that may play a role in carbohydrate metabolism

Structure of LP2179, the first representative of Pfam family PF08866, suggests a new fold with a role in amino-acid metabolism

Structure of a class C GPCR metabotropic glutamate receptor 1 bound to an allosteric modulator

Structure of a membrane-attack complex/perforin (MACPF) family protein from the human gut symbiont Bacteroides thetaiotaomicron

Structure of a putative NTP pyrophosphohydrolase: YP_001813558.1 from Exiguobacterium sibiricum 255-15

Structure of a tryptophanyl-tRNA synthetase containing an iron–sulfur cluster

Structure of an agonist-bound human A2A adenosine receptor

Structure of an essential bacterial protein YeaZ (TM0874) from Thermotoga maritima at 2.5 Å resolution

Structure of the Angiotensin receptor revealed by serial femtosecond crystallography.