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List of works by Ewa Lech-Marańda

2-Chlorodeoxyadenosine (2-CDA) does not Change the Expression of Fas Antigen on Chronic Lymphocytic Leukaemia Cells ⬇️

scientific article published on January 1, 2000

A 5-year follow-up to evaluate the efficacy and safety of ofatumumab added to fludarabine and cyclophosphamide in patients with relapsed chronic lymphocytic leukemia: final analysis of the COMPLEMENT 2 trial

scientific article published on 28 February 2020

A Specific CD44lo CD25lo Subpopulation of Regulatory T Cells Inhibits Anti-Leukemic Immune Response and Promotes the Progression in a Mouse Model of Chronic Lymphocytic Leukemia

scientific article published on 28 February 2022

A multicenter, open, non-comparative, phase II study of the combination of cladribine (2-chlorodeoxyadenosine), cytarabine, and G-CSF as induction therapy in refractory acute myeloid leukemia - a report of the Polish Adult Leukemia Group (PALG).

scientific article published in September 2003

A multicenter, open, noncomparative, phase II study of the combination of cladribine (2-chlorodeoxyadenosine), cytarabine, granulocyte colony-stimulating factor and mitoxantrone as induction therapy in refractory acute myeloid leukemia: a report of

scientific article published on 27 April 2005

A novel, dual pan-PIM/FLT3 inhibitor SEL24 exhibits broad therapeutic potential in acute myeloid leukemia.

scientific article published on 30 March 2018

Bendamustine alone or with rituximab modifies expression of apoptosis-regulating genes and proteins of CLL cells, depending on IGVH mutational status

scientific article published on 06 September 2018

Bendamustine as monotherapy and in combination regimens for the treatment of chronic lymphocytic leukemia and non-hodgkin lymphoma: a retrospective analysis

scientific article

Biology and clinical pharmacology of tumor necrosis factor alpha

scientific article published on 01 June 1997

Blinatumomab versus Chemotherapy for Advanced Acute Lymphoblastic Leukemia

scientific article published on March 2017

Brentuximab Vedotin with Chemotherapy for Stage III or IV Hodgkin's Lymphoma

scientific article published on 10 December 2017

Brentuximab vedotin with chemotherapy for stage III or IV classical Hodgkin lymphoma (ECHELON-1): 5-year update of an international, open-label, randomised, phase 3 trial

Brentuximab vedotin with chemotherapy for stage III/IV classical Hodgkin lymphoma: 3-year update of the ECHELON-1 study

scientific article published on 01 March 2020

Case-adjusted bortezomib-based strategy in routine therapy of relapsed/refractory multiple myeloma shown to be highly effective--a report by Polish Myeloma Study Group.

scientific article

Circulating VEGF and its soluble receptors sVEGFR-1 and sVEGFR-2 in patients with acute leukemia

scientific article

Cladribine combined with cyclophosphamide and mitoxantrone is an active salvage therapy in advanced non-Hodgkin's lymphoma.

scientific article

Cladribine in combination with mitoxantrone and cyclophosphamide(CMC) in the treatment of heavily pre-treated patients with advanced indolent lymphoid malignancies.

scientific article

Clinical characteristics and treatment outcomes in IgE multiple myeloma: A case-control study.

scientific article

Clofarabine as a novel nucleoside analogue approved to treat patients with haematological malignancies: mechanism of action and clinical activity

scientific article

Combination regimen of cladribine (2-chlorodeoxyadenosine), cytarabine and G-CSF (CLAG) as induction therapy for patients with relapsed or refractory acute myeloid leukemia

scientific article

Comparable Efficacy of Idelalisib Plus Rituximab and Ibrutinib in Relapsed/refractory Chronic Lymphocytic Leukemia: A Retrospective Case Matched Study of the Polish Adult Leukemia Group (PALG)

scientific article published on 01 May 2018

Comparison of high-resolution melting analysis with direct sequencing for the detection of recurrent mutations in DNA methyltransferase 3A and isocitrate dehydrogenase 1 and 2 genes in acute myeloid leukemia patients.

scientific article published on 13 May 2015

Current status of older and new purine nucleoside analogues in the treatment of lymphoproliferative diseases.

scientific article published on 23 March 2009

Cytotoxic activity of the selected pyridinium salts against murine leukemia L1210

scientific article published on 01 March 2007

Decreased Activity of Blood Acid Sphingomyelinase in the Course of Multiple Myeloma

scientific article published on 30 November 2019

Defective Sphingolipids Metabolism and Tumor Associated Macrophages as the Possible Links Between Gaucher Disease and Blood Cancer Development

article

Depsipeptide (FK228) as a novel histone deacetylase inhibitor: mechanism of action and anticancer activity

scientific article published on October 2007

Early induction intensification with cladribine, cytarabine, and mitoxantrone (CLAM) in AML patients treated with the DAC induction regimen: a prospective, non-randomized, phase II study of the Polish Adult Leukemia Group (PALG)

scientific article published on 29 October 2019

Efficacy and safety of lenalidomide treatment in multiple myeloma (MM) patients--Report of the Polish Myeloma Group

scientific article published on 15 November 2015

Efficacy and safety of oral panobinostat plus subcutaneous bortezomib and oral dexamethasone in patients with relapsed or relapsed and refractory multiple myeloma (PANORAMA 3): an open-label, randomised, phase 2 study

scientific article published on 04 December 2020

Efficacy of high-dose corticosteroid-based treatment for chronic lymphocytic leukemia patients with p53 abnormalities in the era of B-cell receptor inhibitors

scientific article published on 10 July 2020

Elevated IL-10 plasma levels correlate with poor prognosis in diffuse large B-cell lymphoma

scientific article published on 01 March 2006

Evaluation of circulating endothelial cells as noninvasive marker of angiogenesis in patients with chronic lymphocytic leukemia

scientific article published on 01 January 2009

Exposure-adjusted adverse events comparing blinatumomab with chemotherapy in advanced acute lymphoblastic leukemia

scientific article published on 01 July 2018

FOXO1 activation is an effector of SYK and AKT inhibition in tonic BCR signal-dependent diffuse large B-cell lymphomas.

scientific article published on 19 November 2015

FOXO1 promotes resistance of non-Hodgkin lymphomas to anti-CD20-based therapy

scientific article published on 25 January 2018

Genetic polymorphisms in the proximal IL-10 promoter and susceptibility to non-Hodgkin lymphoma

scientific article published on 01 November 2007

HDAC6 inhibition upregulates CD20 levels and increases the efficacy of anti-CD20 monoclonal antibodies

scientific article

HLA-G and MHC Class II Protein Expression in Diffuse Large B-Cell Lymphoma

scientific article published on 14 December 2015

Hematological malignancies in Polish population: what are the predictors of outcome in patients admitted to Intensive Care Unit?

scientific article published on 02 May 2020

Hepatitis B virus screening in patients with non-Hodgkin lymphoma in clinical practice in Poland - a report of the Polish Lymphoma Research Group

scientific article published on 18 July 2019

High incidence of intact or fragmented immunoglobulin in urine of patients with multiple myeloma

scientific article published on 13 May 2015

Hodgkin's lymphoma mimicking tuberculosis in cervical lymph nodes

scientific article published on March 2014

Human leukocyte antigen-G polymorphisms influence the clinical outcome in diffuse large B-cell lymphoma

scientific article published on 01 March 2015

Human leukocyte antigens HLA DRB1 influence clinical outcome of chronic lymphocytic leukemia?

scientific article published on 01 May 2007

Human leukocyte antigens class II and tumor necrosis factor genetic polymorphisms are independent predictors of non-Hodgkin lymphoma outcome

scientific article published in October 2002

Immunogenicity of influenza vaccination in patients with non-Hodgkin lymphoma

scientific article published on 08 March 2007

Increased expression of E3 ubiquitin ligases targeting p53 in CLL patients with wild-type TP53 exhibits associations with clinical features of the disease.

scientific article published on 16 November 2015

Infectious complications in patients with acute myeloid leukemia treated according to the protocol with daunorubicin and cytarabine with or without addition of cladribine. A multicenter study by the Polish Adult Leukemia Group (PALG).

scientific article

Influence of cladribine alone and in combination with cyclophosphamide or cyclophosphamide and mitoxantrone on bone marrow angiogenesis in chronic lymphocytic leukemia

scientific article published on 01 May 2007

Influence of gemcitabine (2',2'-difluoro-deoxycytidine) and 2-chlorodeoxyadenosine on growth of normal and leukemic cells in vitro

scientific article published on 01 November 2000

Inhibition of thioredoxin-dependent HO removal sensitizes malignant B-cells to pharmacological ascorbate

scientific article published on 29 November 2018

Interleukin-10 gene promoter polymorphisms influence the clinical outcome of diffuse large B-cell lymphoma

scientific article published on 30 December 2003

Intragenic Variations in BTLA Gene Influence mRNA Expression of BTLA Gene in Chronic Lymphocytic Leukemia Patients and Confer Susceptibility to Chronic Lymphocytic Leukemia

scientific article published on 08 December 2016

Long-term Efficacy of Ibrutinib in Relapsed or Refractory Chronic Lymphocytic Leukemia: Results of the Polish Adult Leukemia Study Group Observational Study

scientific article published on 01 July 2020

Long-term results of the Polish Adult Leukemia Group PALG-CLL2 phase III randomized study comparing cladribine-based combinations in chronic lymphocytic leukemia.

scientific article published on 14 November 2013

MEK Inhibition Sensitizes Precursor B-Cell Acute Lymphoblastic Leukemia (B-ALL) Cells to Dexamethasone through Modulation of mTOR Activity and Stimulation of Autophagy

scientific article

Microenvironment-induced PIM kinases promote CXCR4-triggered mTOR pathway required for chronic lymphocytic leukaemia cell migration.

scientific article published on 17 April 2018

Necrotizing gastritis in a patient in severe neutropenia

scientific article published on December 2014

Novel and emerging drugs for acute lymphoblastic leukemia

scientific article published on June 2012

Novel purine nucleoside analogues for hematological malignancies

scientific article published on June 2008

Novel systemic drugs for cutaneous T-cell lymphoma

scientific article published on January 2011

Outcomes of treatment with dose-adjusted EPOCH-R or R-CHOP in primary mediastinal large B-cell lymphoma

scientific article published on 27 October 2019

Pharmacological and clinical studies on purine nucleoside analogs--new anticancer agents

scientific article

Plasma TNF-alpha and IL-10 level-based prognostic model predicts outcome of patients with diffuse large B-Cell lymphoma in different risk groups defined by the International Prognostic Index

scientific article published on 27 February 2010

Polish experience of lenalidomide in the treatment of lower risk myelodysplastic syndrome with isolated del(5q).

scientific article

Polymorphism in IKZF1 gene affects clinical outcome in diffuse large B-cell lymphoma

scientific article

Polymorphisms of TNF and IL-10 genes and clinical outcome of patients with chronic lymphocytic leukemia

scientific article

Pretreatment levels of vascular endothelial growth factor in plasma predict a complete remission rate and time to relapse or progression in patients with diffuse large B-cell lymphoma

scientific article published on 3 January 2013

Prognostic value of the bone marrow microvessel density in progressive B-cell chronic lymphocytic leukemia

scientific article published on 01 July 2010

Prophylaxis and therapy of central nervous system involvement in adult acute lymphoblastic leukemia: recommendations of the Polish Adult Leukemia Group

scientific article published on 01 June 2008

Prophylaxis of hepatitis B virus (HBV) infection reactivation - recommendations of the Working Group for prevention of HBV reactivation

scientific article published on 05 September 2019

Przeszczepienie krwiotwórczych komórek macierzystych w nawrotowej wtórnej limfohistiocytozie hemofagocytarnej

scientific article published on 7 April 2017

Purine nucleoside analogs as immunosuppressive and antineoplastic agents: mechanism of action and clinical activity

scientific article published on January 2006

Quiz. Correct answer to the quiz. Check your diagnosis Hodgkin’s lymphoma mimicking tuberculosis in cervical lymph nodes

scientific article published in 2014

Randomized comparison of cladribine alone or in combination with cyclophosphamide, and cyclophosphamide, vincristine and prednisone in previously untreated low-grade B-cell non-Hodgkin lymphoma patients: final report of the Polish Lymphoma Research

scientific article published on 01 July 2008

Randomized phase 2 study of otlertuzumab and bendamustine versus bendamustine in patients with relapsed chronic lymphocytic leukaemia

scientific article published on 15 December 2016

Real-life experience with bortezomib-based regimens in elderly comorbid patients with newly diagnosed multiple myeloma - Polish retrospective multicenter analysis

scientific article published on 14 September 2017

Rituximab plus fludarabine and cyclophosphamide or other agents in chronic lymphocytic leukemia

scientific article published on October 2010

SYK inhibition targets acute myeloid leukemia stem cells by blocking their oxidative metabolism

scientific article published on 06 November 2020

Safe administration of rituximab in patients with chronic lymphocytic leukemia and a history of obinutuzumab‑associated anaphylaxis

scientific article published on 31 August 2018

Serum tumor necrosis factor-α and interleukin-10 levels as markers to predict outcome of patients with chronic lymphocytic leukemia in different risk groups defined by the IGHV mutation status

scientific article published on 04 September 2012

Sorafenib improves rituximab and ofatumumab efficacy by decreasing the expression of complement regulatory proteins

scientific article published on 10 April 2015

Targeting the thioredoxin system as a novel strategy against B-cell acute lymphoblastic leukemia

scientific article published on 05 April 2019

The efficacy and safety of pomalidomide in relapsed/refractory multiple myeloma in a “real-world” study: Polish Myeloma Group experience

scientific article published on 12 July 2018

The interaction of gemcitabine and cytarabine on murine leukemias L1210 or P388 and on human normal and leukemic cell growth in vitro

scientific article

Toll-like receptors and their role in carcinogenesis and anti-tumor treatment.

scientific article published on 18 December 2008

Toll-like receptors and their role in hematologic malignancies

scientific article published on April 2009

Treatment adherence in chronic myeloid leukaemia patients receiving tyrosine kinase inhibitors

scientific article

Treatment of elderly patients with acute myeloid leukemia adjusted for performance status and presence of comorbidities: a Polish Adult Leukemia Group study

scientific article published on 21 January 2015

Use of L-asparaginase in acute lymphoblastic leukemia: recommendations of the Polish Adult Leukemia Group

scientific article published on 01 November 2008

Zalecenia Polskiej Grupy Szpiczakowej dotyczące rozpoznawania i leczenia szpiczaka plazmocytowego oraz innych dyskrazji plazmocytowych na rok 2015

scientific article published in May 2015

Zalecenia Polskiej Grupy Szpiczakowej dotyczące rozpoznawania i leczenia szpiczaka plazmocytowego oraz innych dyskrazji plazmocytowych na rok 2016

scientific article published in April 2016

Zalecenia Polskiej Grupy Szpiczakowej dotyczące rozpoznawania i leczenia szpiczaka plazmocytowego oraz innych dyskrazji plazmocytowych na rok 2017

scientific article published in April 2017

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